Targeting human CD34+ hematopoietic stem cells with anti-CD45 X anti-myosin light-chain bispecific antibody preserves cardiac function in myocardial infarction

Journal of Applied Physiology

Volumn 104, Issue 6, 2008, Pages 1793-1800

  Zhao, Ting C ^a,e   Tseng, Andy ^a   Yano, Naohiro ^a   Tseng, YiTang ^a   Davol, Pamela A ^b   Lee, Randall J ^c   Lum, Lawrence G ^d   Padbury, James F ^a  

^a BROWN UNIVERSITY   (United States)

^b ROGER WILLIAMS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

^e WOMEN AND INFANTS HOSPITAL   (United States)

Author keywords

Bispecific antibody; CD34+ hematopoietic stem cell; Mouse; Myocardium

Indexed keywords

BISPECIFIC ANTIBODY; CD34 ANTIBODY; CD45 ANTIGEN; MYOSIN ANTIBODY; MYOSIN LIGHT CHAIN; CD34 ANTIGEN; PTPRC PROTEIN, MOUSE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE FIBROSIS; HEART VENTRICLE FUNCTION; HEMATOPOIETIC STEM CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; ISOLATED HEART; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; DISEASE MODEL; FIBROSIS; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART VENTRICLE REMODELING; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; ANTIBODIES, BISPECIFIC; ANTIGENS, CD34; ANTIGENS, CD45; DISEASE MODELS, ANIMAL; FIBROSIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED ICR; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOSIN LIGHT CHAINS; NEOVASCULARIZATION, PHYSIOLOGIC; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 49649102917     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01109.2007     Document Type: Article

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