N-glycans and the N terminus of protein C inhibitor affect the cofactor-enhanced rates of thrombin inhibition

Journal of Biological Chemistry

Volumn 283, Issue 27, 2008, Pages 18601-18611

  Sun, Wei ^a   Parry, Simon ^a   Panico, Maria ^b,c   Morris, Howard R ^d   Kjellberg, Margareta ^a   Engström, Åke ^a   Dell, Anne ^b   Schedin Weiss, Sophia ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c M SCAN Ltd   (United Kingdom)

^d LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BLOOD; COMPUTER PERIPHERAL EQUIPMENT; ESTERIFICATION; GLYCOPROTEINS; GLYCOSYLATION; POLYSACCHARIDES;

ATHEROSCLEROTIC PLAQUES; COFACTOR; FUNCTIONAL DIFFERENCES; GLYCAN STRUCTURES; GLYCANS; GLYCOSYLATED; N TERMINUSES; PROTEIN C INHIBITORS; SERINE PROTEASE INHIBITORS; SOLUTION CONDITIONS; TERMINAL REGIONS; THROMBIN INHIBITIONS; THROMBOMODULIN;

INTERFACES (COMPUTER);

ASPARAGINE; EPITOPE; FUCOSE; GLYCAN DERIVATIVE; HEPARIN; PLASMINOGEN ACTIVATOR INHIBITOR; SIALYL LEWIS X ANTIGEN; THROMBIN; THROMBOMODULIN; PLASMINOGEN ACTIVATOR INHIBITOR 3; POLYSACCHARIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; HUMAN; HYPERCOAGULABILITY; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN STRUCTURE; ATHEROSCLEROSIS; CHEMISTRY; ENZYME SPECIFICITY; GLYCOSYLATION; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; THROMBOPHILIA;

TETRA;

ATHEROSCLEROSIS; GLYCOSYLATION; HEPARIN; HUMANS; POLYSACCHARIDES; PROTEIN C INHIBITOR; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; THROMBIN; THROMBOMODULIN; THROMBOPHILIA;

EID: 49649093374     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800608200     Document Type: Article

References (42)

1. Silverman, G. A., Bird, P. I., Carrell, R. W., Church, F. C., Coughlin, P. B., Gettins, P. G., Irving, J. A., Lomas, D. A., Luke, C. J., Moyer, R. W., Pemberton, P. A., Remold-O'Donnell, E., Salvesen, G. S., Travis, J., and Whisstock, J. C. (2001) J. Biol. Chem. 276, 33293-33296
2. Pike, R. N., Bottomley, S. P., Irving, J. A., Bird, P. I., and Whisstock, J. C. (2002) IUBMB Life 54, 1-7
3. Gettins, P. G. (2002) Chem. Rev. 102, 4751-4804
4. Krebs, M., Uhrin, P., Vales, A., Prendes-Garcia, M. J., Wojta, J., Geiger, M., and Binder, B. R. (1999) J. Invest. Dermatol. 113, 32-37
5. Pike, R. N., Buckle, A. M., le Bonniec, B. F., and Church, F. C. (2005) FEBS J. 272, 4842-4851
6. Geiger, M. (2007) Thromb. Haemost. 97, 343-347
7. Geiger, M., Zechmeister-Machhart, M., Uhrin, P., Hufnagl, P., Ecke, S., Priglinger, U., Xu, J., Zheng, X., and Binder, B. R. (1996) Immunopharmacology 32, 53-56
8. Kazama, Y., Masahiro, N., Yamagishi, R., Takahashi, K., Sakuragawa, N., and Koide, T. (1987) Thromb. Res. 48, 179-185
9. Pratt, C. W., and Church, F. C. (1992) J. Biol. Chem. 267, 8789-8794
10. Ecke, S., Geiger, M., and Binder, B. R. (1992) Ann. N. Y. Acad. Sci. 667, 84-86
11. Rezaie, A. R., Cooper, S. T., Church, F. C., and Esmon, C. T. (1995) J. Biol. Chem. 270, 25336-25339
12. Marlar, R. A., and Griffin, J. H. (1980) J. Clin. Invest. 66, 1186-1189
13. Elisen, M. G., Maseland, M. H., Church, F. C., Bouma, B. N., and Meijers, J. C. (1996) Thromb. Haemost. 75, 760-766
14. Laurell, M., Carlson, T. H., and Stenflo, J. (1988) Thromb. Haemost. 60, 334-339
15. Laurell, M., and Stenflo, J. (1989) Thromb. Haemost. 62, 885-891
16. Strandberg, K., Kjellberg, M., Erb, E. M., Persson, U., Mosher, D. F., Villoutreix, B. O., and Stenflo, J. (2000) Biochemistry 39, 15713-15720
17. Olson, S. T., Bjork, I., and Shore, J. D. (1993) Methods Enzymol. 222, 525-559
18. Dell, A., Khoo, K. H., Panico, M., McDowell, R. A., Etienne, A. T., Reason, A. J., and Morris, H. R. (1993) Glycobiology: A Practical Approach, pp. 187-222, Oxford University Press, Oxford
19. Streusand, V. J., Björk, I., Gettins, P. G., Petitou, M., and Olson, S. T. (1995) J. Biol. Chem. 270, 9043-9051
20. Olson, S. T. (1988) J. Biol. Chem. 263, 1698-1708
21. Pineda, A. O., Cantwell, A. M., Bush, L. A., Rose, T., and Di Cera, E. (2002) J. Biol. Chem. 277, 32015-32019
22. Yang, L., Manithody, C., Walston, T. D., Cooper, S. T., and Rezaie, A. R. (2003) J. Biol. Chem. 278, 37465-37470
23. Li, W., Adams, T. E., Nangalia, J., Esmon, C. T., and Huntington, J. A. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 4661-4666
24. Medzihradszky, K. F. (2005) Methods Enzymol. 405, 116-138
25. Izutani, W., Fujita, M., Nishizawa, K., and Koga, J. (2001) Thromb. Res. 104, 65-74
26. Spik, G., Coddeville, B., Strecker, G., Montreuil, J., Regoeczi, E., Chindemi, P. A., and Rudolph, J. R. (1991) Eur. J. Biochem. 195, 397-405
27. Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C., and Ferrin, T. E. (2004) J. Comput. Chem. 25, 1605-1612
28. Di Cera, E., Page, M. J., Bah, A., Bush-Pelc, L. A., and Garvey, L. C. (2007) Phys. Chem. Chem. Phys. 9, 1291-1306
29. Suzuki, K., Nishioka, J., and Hashimoto, S. (1983) J. Biol. Chem. 258, 163-168
30. Strukova, S. (2006) Front. Biosci. 11, 59-80
31. Malleier, J. M., Oskolkova, O., Bochkov, V., Jerabek, I., Sokolikova, B., Perkmann, T., Breuss, J., Binder, B. R., and Geiger, M. (2007) Blood 109, 4769-4776
32. Hayashi, T., Nishioka, J., Nakagawa, N., Kamada, H., Gabazza, E. C., Kobayashi, T., Hattori, A., and Suzuki, K. (2007) J. Thromb. Haemost. 5, 1477-1485
33. Fujita, M., Izutani, W., and Komurasaki, Y. (2000) Thromb. Haemost. 84, 54-58
34. Nishii, Y., Gabazza, E. C., Fujimoto, H., Nakahara, H., Takagi, T., Bruno, N., D'Alessandro-Gabazza, C. N., Maruyama, J., Maruyama, K., Hayashi, T., Adachi, Y., Suzuki, K., and Taguchi, O. (2006) J. Thromb. Haemost. 4, 2331-2339
35. Kaplan, H. A., Welply, J. K., and Lennarz, W. J. (1987) Biochim. Biophys. Acta 906, 161-173
36. Ben-Dor, S., Esterman, N., Rubin, E., and Sharon, N. (2004) Glycobiology 14, 95-101
37. Fujita, M., Izutani, W., Takahashi, K., Nishizawa, K., Shirono, H., and Koga, J. (2002) Thromb. Res. 105, 95-102
38. Suzuki, K. (1984) Semin. Thromb. Hemost. 10, 154-161
39. Shirk, R. A., Elisen, M. G., Meijers, J. C., and Church, F. C. (1994) J. Biol. Chem. 269, 28690-28695
40. Li, W., Adams, T. E., Kjellberg, M., Stenflo, J., and Huntington, J. A. (2007) J. Biol. Chem. 282, 13759-13768
41. Kuhn, L. A., Griffin, J. H., Fisher, C. L., Greengard, J. S., Bouma, B. N., Espana, F., and Tainer, J. A. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 8506-8510
42. Fortenberry, Y. M., Whinna, H. C., Cooper, S. T., Myles, T., Leung, L. L., and Church, F. C. (2007) J. Thromb. Haemost. 5, 1486-1492