Essential thrombin residues for inhibition by protein C inhibitor with the cofactors heparin and thrombomodulin

Journal of Thrombosis and Haemostasis

Volumn 5, Issue 7, 2007, Pages 1486-1492

  Fortenberry, Yolanda M ^a,e   Whinna, H C ^a   Cooper, S T ^b   Myles, T ^c   Leung, L L K ^c   Church, F C ^a,d  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WISCONSIN LA CROSSE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Department of Pharmacology ^*

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antithrombin; Chondroitin sulfate; Protein C inhibitor; Serpins; Thrombin; Thrombomodulin

Indexed keywords

ANTITHROMBIN; ARGININE; CHONDROITIN SULFATE; GLUTAMINE; GLYCINE; HEPARIN COFACTOR; LYSINE; PLASMINOGEN ACTIVATOR INHIBITOR 3; SERINE PROTEINASE INHIBITOR; SODIUM; THROMBIN; THROMBOMODULIN; TYROSINE;

ARTICLE; BINDING SITE; CATALYSIS; COMPETITIVE INHIBITION; CONTROLLED STUDY; HUMAN; MUTANT; NONHUMAN; PRIORITY JOURNAL; RABBIT; RESIDUE ANALYSIS;

AMINO ACID SUBSTITUTION; BINDING SITES; HEPARIN; HUMANS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEIN C INHIBITOR; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; THROMBIN; THROMBOMODULIN;

EID: 34250744633     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2007.02574.x     Document Type: Article

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