Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1782, Issue 9, 2008, Pages 517-522

  Macedo, Bárbara ^a   Batista, Ana Rita ^a,b   Ferreira, Nelson ^a,b   Almeida, Maria Rosário ^a,b   Saraiva, Maria João ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Amyloid; Apoptosis; Cytotoxicity; ER stress; Protein aggregation; Tauroursodeoxycholic acid (TUDCA)

Indexed keywords

3 NITROTYROSINE; BIOLOGICAL MARKER; DEATH RECEPTOR; PREALBUMIN; TAUROURSODEOXYCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FAMILIAL AMYLOID POLYNEUROPATHY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TRANSGENIC MOUSE; WESTERN BLOTTING;

AMYLOID NEUROPATHIES, FAMILIAL; ANIMALS; ANTIGENS, CD95; APOPTOSIS; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; GASTROINTESTINAL TRACT; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; METHIONINE; MICE; MICE, TRANSGENIC; MOLECULAR CHAPERONES; MUTANT PROTEINS; MUTATION; OXIDATION-REDUCTION; PREALBUMIN; PROTEIN STRUCTURE, QUATERNARY; TAUROCHENODEOXYCHOLIC ACID; THERMODYNAMICS; TYROSINE;

MUS MUSCULUS;

EID: 49349097870     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2008.05.005     Document Type: Article

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