Electrically neutral microheterogeneity of human plasma transthyretin (prealbumin) detected by isoelectric focusing in urea gradients

Electrophoresis

Volumn 20, Issue 7, 1999, Pages 1349-1364

  Altland, Klaus ^a   Winter, Pia ^a   Sauerborn, Markus Karl ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Conformational stability; Electrically silent mutations; Familial amyloidotic polyneuropathy; Human transthyretin; Urea titration

Indexed keywords

AMINO ACIDS; CONFORMATIONS; ELECTROPHORESIS; METABOLISM; MONOMERS; PLASMA (HUMAN); PLASMA STABILITY;

CONFORMATIONAL STABILITIES; ELECTRICALLY SILENT MUTATION; FAMILIAL AMYLOIDOTIC POLYNEUROPATHY; HUMAN PLASMAS; HUMAN TRANSTHYRETIN; ISOELECTRIC FOCUSING; SILENT MUTATIONS; TRANSTHYRETIN; UREA GRADIENT; UREA TITRATION;

UREA;

PREALBUMIN; UREA;

AMYLOID NEUROPATHY; ARTICLE; CONFORMATION; ELECTROPHORESIS; GENE MUTATION; HUMAN; ISOELECTRIC FOCUSING; PROTEIN EXPRESSION;

EID: 0032994562     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2683(19990601)20:7<1349::AID-ELPS1349>3.0.CO;2-5     Document Type: Article

References (29)

1. Kanda, Y., Goodman, D. S., Canfield, R. E., Morgan, F. J., J. Biol. Chem. 1974, 249, 6796-6805.
2. Blake, C. C. F., Swan, I. D. A., Rerat, C., Berthou, J., Laurant, A., Rerat, B., J. Mol. Biol. 1971, 61, 217-224.
3. Monaco, H. L., Rizzi, M., Coda, A., Science 1995, 268, 1039-1041.
4. Altland, K., Rauh, S., Hackler, R., Electrophoresis 1981, 2, 148-155.
5. Altland, K., Becher, P., Banzhoff, A., Electrophoresis 1987, 8, 293-297.
6. Benson, M. D., in: Sciver, C. R., Beaudet, A. L., Sly, W. S., Valle, D. (Eds.), The Metabolic Basis of Inherited Diseases, McGraw-Hill, New York 1995, Vol. 3, pp.4139-4191.
7. Creighton, T. E., Methods Enzymol. 1986, 131, 156-172.
8. Altland, K., Banzhoff, A., Hackler, R., Rossmann, U., Electrophoresis 1984, 5, 379-381.
9. Altland, K., Hackler, R., in: Neuhoff, V. (Ed.), Electrophoresis '84, Verlag Chemie, Weinheim 1984, pp. 362-377.
10. Altland, K., Banzhoff, A., Electrophoresis 1986, 7, 529-533.
11. Patestos, N. P., Fauth, M., Radola, B. J., Electrophoresis 1988, 9, 488-496.
12. Patestos, N. P., Fauth, M., Radola, B. J., in: Radola, B. J. (Ed.), Electrophoresis Forum '89, Technische Universität, München 1989, pp. 321-325.
13. Merril, C. R., Harrington, M. G., Clin. Chem. 1984, 30, 1838-1942.
14. Turk, D., Ph. D. Thesis, Technical University München 1992.
15. Harrison, H. H., Gordon, E. D., Nichols, W. C., Benson, M. D., Am. J. Med. Genet. 1991, 39, 442.
16. Almeida, M. R., Altland, K., Rauh, S., Gawinowicz, M. A., Moreira, P., Costa, P. P., Saraiva, M. J. M., Biochim. Biophys. Acta 1991, 1097, 224-226.
17. Uemichi, T., Murrell, J. R., Zeldenrust, S., Benson, M. D., J. Med. Genet. 1992, 29, 888-891.
18. Jenne, D. E., Denzel, K., Blätzinger, P., Winter, P., Obermaier, B., Linke, R. P., Altland, K., Proc. Natl. Acad. Sci. USA 1996, 93, 6302-6307.
19. Ferlini, A., Salvi, F. Uncini, A., El-Chamie, J., Winter, P., Altland, K., Repetto, M., Littardi, M., Campoleoni, A., Vezzoni, P., Patrosso, M. C., Clin. Genet. 1996, 49, 10-14.
20. Alves, I. L., Altland, K., Almeida, M. R., Winter, P., Saraiva, M. J. M., Hum. Mutation 1997, 9, 226-233.
21. Hamilton, J. A., Steinrauf, L. K., Braden, B. C., Liepnicks, J., Benson, M. D., Holmgren, G., Sandgren, O., Stehen, L., J. Biol. Chem. 1993, 268, 2416-2424.
22. Duan, W., Richardson, S. J., Babon, J. J., Heyes, R. J., Southwell, B. R., Harms, P. J., Wettenhall, R. E. H., Dziegielewska, K. M., Selwood, L., Bradley, A. J., Brack, C. M., Schreiber, G., Eur. J. Biochem. 1995, 227, 396-406.
23. Folding, P., Fex, G., Scand. J. Clin. Lab. Invest. 1984, 44, 231-238.
24. Hutchinson, W. L., Alves, I. L., Saraiva, M. J., Pepys, M. B., Neuromusc. Disord. 1996, 6, Suppl. 1, S16.
25. Terasaki, H., Ando, Y., Suhr, O., Ohlsoson, P.-I., Obayashi, K., Yamashita, T., Yoshimatsu, S., Suga, M., Uchino, M., Ando, M., Biochem. Biophys, Res. Comm. 1998, 249, 26-30.
26. Brune, D. C., Anal. Biochem. 1992, 207, 285-290.
27. Altland, K., Becher, P., Rossmann, U., Bjellqvist, B., Electrophoresis 1988, 9, 474-485.
28. Altland, K., Hackler, R., Rossmann, U., Electrophoresis 1986, 7, 251-259.
29. Altland, K., Benson, M. D., Ferlini, A., Husby, G., Linke, R. P., Salvi, F., Saraiva, M. J. M., Skinner, M., Sletten, K., Steinmetz, A., Winter, P., Neuromusc. Disord. 1996, 6, Suppl. 1, S21.