Human neutrophil peptides upregulate expression of COX-2 and endothelin-1 by inducing oxidative stress

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 6, 2008, Pages

  Syeda, Farisa ^a,b,c   Tullis, Elizabeth ^a,b   Slutsky, Arthur S ^a,c   Zhang, Haibo ^a,b,c,d  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d Queen Wing   (Canada)

Author keywords

Immunity; Inflammation; Leukocyte

Indexed keywords

3 NITROTYROSINE; ACETYLCYSTEINE; ANGIOTENSIN II; BETA ACTIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; ENDOTHELIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; OXYGEN RADICAL; PEPTIDE DERIVATIVE; PROSTACYCLIN; 3-NITROTYROSINE; DRUG DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDE; PROTEIN KINASE INHIBITOR; PTGS1 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; SCAVENGER; TYROSINE;

ARTICLE; BLOOD VESSEL TONE; CARDIOVASCULAR DISEASE; CELL ACTIVATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; UPREGULATION; VASCULAR ENDOTHELIUM; CELL CULTURE; DRUG EFFECT; ENZYMOLOGY; METABOLISM; TIME;

ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CELLS, CULTURED; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENDOTHELIAL CELLS; ENDOTHELIN-1; EPOPROSTENOL; FREE RADICAL SCAVENGERS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUTROPHILS; NF-KAPPA B; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PROTEIN KINASE INHIBITORS; TIME FACTORS; TYROSINE; UP-REGULATION;

EID: 49249092790     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00211.2008     Document Type: Article

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