Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and ΔF508 CFTR

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1783, Issue 9, 2008, Pages 1585-1594

  Okiyoneda, Tsukasa ^a   Niibori, Akiko ^a   Harada, Kazutsune ^a   Kohno, Taijun ^a   Michalak, Marek ^b   Duszyk, Marek ^b   Wada, Ikuo ^c   Ikawa, Masahito ^d   Shuto, Tsuyoshi ^a   Suico, Mary Ann ^a   Kai, Hirofumi ^a  

^a Department of Molecular Medicine   (Japan)

^b UNIVERSITY OF ALBERTA   (Canada)

^c FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Calnexin; Calnexin knockout; CFTR; ER quality control

Indexed keywords

CALNEXIN; CHLORIDE CHANNEL; PROTEASOME; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRAIN BHK; CHO CELL; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYSTIC FIBROSIS; ENDOPLASMIC RETICULUM; IMMUNOCYTOCHEMISTRY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROCESSING; ANIMAL; CELL LINE; CHEMISTRY; EPITHELIUM; GENE DELETION; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY;

MUS;

ANIMALS; CALNEXIN; CELL LINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOPLASMIC RETICULUM; EPITHELIUM; MICE; MICE, KNOCKOUT; PROTEIN FOLDING; SEQUENCE DELETION;

EID: 49149090813     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2008.04.002     Document Type: Article

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