Stereoselective metabolism and tissue retention in rats of the individual enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

Carcinogenesis

Volumn 25, Issue 7, 2004, Pages 1237-1242

  Zimmerman, Cheryl L ^a   Wu, Zheng ^a   Upadhyaya, Pramod ^a   Hecht, Stephen S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANOL; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CARCINOGEN; GLUCURONIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT; BILE FLOW; BLOOD LEVEL; CANNULATION; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; CHIRALITY; CONTROLLED STUDY; DETOXIFICATION; ENANTIOMER; GAS CHROMATOGRAPHY; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LUNG CARCINOGENESIS; MALE; METABOLITE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; STEREOCHEMISTRY; TISSUE DISTRIBUTION; TISSUE METABOLISM; TOBACCO; TOXICOKINETICS; URINARY EXCRETION;

ANIMALS; MALE; NITROSAMINES; ORGAN SPECIFICITY; PYRIDINES; RATS; RATS, INBRED F344; TIME FACTORS;

EID: 3242760756     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh120     Document Type: Article

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