-
3
-
-
33748323116
-
-
(b) Popsavin, M.; Spaiæ, S.; Svirèev, M.; Kojiæ, V.; Bogdanoviæ, G.; Popsavin, V. Bioorg. Med. Chem. Lett. 2006, 16, 5317-5320.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 5317-5320
-
-
Popsavin, M.1
Spaiæ, S.2
Svirèev, M.3
Kojiæ, V.4
Bogdanoviæ, G.5
Popsavin, V.6
-
4
-
-
0015114233
-
-
(c) Modi, J. D.; Sabnis, S. S.; Deliwala, C. V. J. Med. Chem. 1971, 14, 887-888.
-
(1971)
J. Med. Chem
, vol.14
, pp. 887-888
-
-
Modi, J.D.1
Sabnis, S.S.2
Deliwala, C.V.3
-
5
-
-
0031923545
-
-
Ojika, M.; Suzuki, Y.; Tsukamoto, A.; Sakagami, Y.; Fudou, R.; Yoshimura, T.; Yamanaka, S. J. Antibiot. 1998, 51, 275-281.
-
(1998)
J. Antibiot
, vol.51
, pp. 275-281
-
-
Ojika, M.1
Suzuki, Y.2
Tsukamoto, A.3
Sakagami, Y.4
Fudou, R.5
Yoshimura, T.6
Yamanaka, S.7
-
6
-
-
0032541553
-
-
(b) Suzuki, Y.; Ojika, M.; Sakagami, Y.; Fudou, R.; Yamanka, S. Tetrahedron 1998, 54, 11399-11404.
-
(1998)
Tetrahedron
, vol.54
, pp. 11399-11404
-
-
Suzuki, Y.1
Ojika, M.2
Sakagami, Y.3
Fudou, R.4
Yamanka, S.5
-
7
-
-
4444333859
-
-
(c) Liu, C.-L.; Li, Z.-M.; Zhong, B. J. Fluorine Chem. 2004, 125, 1287-1290.
-
(2004)
J. Fluorine Chem
, vol.125
, pp. 1287-1290
-
-
Liu, C.-L.1
Li, Z.-M.2
Zhong, B.3
-
8
-
-
0037366612
-
-
(d) Ingle, R. D.; Bhingolikar, V. E.; Bondge, S. P.; Mane, R. A. Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 2003, 42B, 695-698.
-
(2003)
Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem
, vol.42 B
, pp. 695-698
-
-
Ingle, R.D.1
Bhingolikar, V.E.2
Bondge, S.P.3
Mane, R.A.4
-
9
-
-
13844306055
-
-
Bagley, M. C.; Dale, J. W.; Merritt, E. A.; Xiong, X. Chem. Rev. 2005, 105, 685-714.
-
(2005)
Chem. Rev
, vol.105
, pp. 685-714
-
-
Bagley, M.C.1
Dale, J.W.2
Merritt, E.A.3
Xiong, X.4
-
10
-
-
34250159079
-
-
(b) Bondock, S.; Khalifa, W.; Fadda, A. A. Eur. J. Med. Chem. 2007, 42, 948-954.
-
(2007)
Eur. J. Med. Chem
, vol.42
, pp. 948-954
-
-
Bondock, S.1
Khalifa, W.2
Fadda, A.A.3
-
11
-
-
34247877632
-
-
(c) Shiradkar, M. R.; Murahari, K. K.; Gangadasu, H. R.; Suresh, T.; Kalyan, C. A.; Panchal, D.; Kaur, R.; Burange, P.; Ghogare, J.; Mokale, V.; Raut, M. Bioorg. Med. Chem. 2007, 15, 3997-4008.
-
(2007)
Bioorg. Med. Chem
, vol.15
, pp. 3997-4008
-
-
Shiradkar, M.R.1
Murahari, K.K.2
Gangadasu, H.R.3
Suresh, T.4
Kalyan, C.A.5
Panchal, D.6
Kaur, R.7
Burange, P.8
Ghogare, J.9
Mokale, V.10
Raut, M.11
-
12
-
-
27644574520
-
-
(d) Hughes, R. A.; Thompson, S. P.; Alcaraz, L.; Moody, C. J. J. Am. Chem. Soc. 2005, 127, 15644-15651.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 15644-15651
-
-
Hughes, R.A.1
Thompson, S.P.2
Alcaraz, L.3
Moody, C.J.4
-
13
-
-
4644312840
-
-
(e) Pucci, M. J.; Branson, J. J.; Barrett, J. F.; DenBleyker, K. L.; Discotto, L. F.; Fung-Tome, J. C.; Ueda, Y. Antimicrob. Agents Chemother. 2004, 48, 3697-3701.
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, pp. 3697-3701
-
-
Pucci, M.J.1
Branson, J.J.2
Barrett, J.F.3
DenBleyker, K.L.4
Discotto, L.F.5
Fung-Tome, J.C.6
Ueda, Y.7
-
14
-
-
2942587365
-
-
Shankaran, K.; Donnelly, K. L.; Shah, S. K.; Guthikonda, R. N.; MacCoss, M.; Mills, S. G.; Gould, S. L.; Malkowitz, L.; Siciliano, S. J.; Springer, M. S.; Carella, A.; Carver, G.; Hazuda, D.; Holmes, K.; Kessler, J.; Lineberger, J.; Miller, M. D.; Emini, E. A.; Schleif, W. A. Bioorg. Med. Chem. Lett. 2004, 14, 3419-3424.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, pp. 3419-3424
-
-
Shankaran, K.1
Donnelly, K.L.2
Shah, S.K.3
Guthikonda, R.N.4
MacCoss, M.5
Mills, S.G.6
Gould, S.L.7
Malkowitz, L.8
Siciliano, S.J.9
Springer, M.S.10
Carella, A.11
Carver, G.12
Hazuda, D.13
Holmes, K.14
Kessler, J.15
Lineberger, J.16
Miller, M.D.17
Emini, E.A.18
Schleif, W.A.19
-
15
-
-
0034712243
-
-
(b) Sharma, S. K.; Tandon, M.; Lown, J. W. J. Org. Chem. 2000, 65, 1102-1107.
-
(2000)
J. Org. Chem
, vol.65
, pp. 1102-1107
-
-
Sharma, S.K.1
Tandon, M.2
Lown, J.W.3
-
16
-
-
34247198421
-
-
Dabideen, D. R.; Cheng, K. F.; Aljabari, B.; Miller, E. J.; Pavlov, V. A.; Al-Abed, Y. J. Med. Chem. 2007, 50, 1993-1997.
-
(2007)
J. Med. Chem
, vol.50
, pp. 1993-1997
-
-
Dabideen, D.R.1
Cheng, K.F.2
Aljabari, B.3
Miller, E.J.4
Pavlov, V.A.5
Al-Abed, Y.6
-
17
-
-
49049111234
-
-
Shin, H. I.; Choi, H. W.; Heo, T. H.; Lee, K. W.; Lee, J. H.; Park, K. S. Isoxazoline derivative and novel process for its preparation. PCT Int. Appl. WO 2006/090997 A1, 2006.
-
(b) Shin, H. I.; Choi, H. W.; Heo, T. H.; Lee, K. W.; Lee, J. H.; Park, K. S. Isoxazoline derivative and novel process for its preparation. PCT Int. Appl. WO 2006/090997 A1, 2006.
-
-
-
-
18
-
-
4644303166
-
-
Hwang, I. T.; Hong, K. S.; Choi, J. S.; Kim, H. R.; Jeon, D. J.; Cho, K. Y. Pestic. Biochem. Physiol. 2004, 80, 123-130.
-
(2004)
Pestic. Biochem. Physiol
, vol.80
, pp. 123-130
-
-
Hwang, I.T.1
Hong, K.S.2
Choi, J.S.3
Kim, H.R.4
Jeon, D.J.5
Cho, K.Y.6
-
19
-
-
49049121988
-
-
(b) Hwang, I. T.; Kim, H. R.; Jeon, D. J.; Hong, K. S.; Song, J. H.; Cho, K. Y. J. Agric. Food. Chem. 2005, 53, 8639-8643.
-
(2005)
J. Agric. Food. Chem
, vol.53
, pp. 8639-8643
-
-
Hwang, I.T.1
Kim, H.R.2
Jeon, D.J.3
Hong, K.S.4
Song, J.H.5
Cho, K.Y.6
-
20
-
-
33544461091
-
-
Mishra, R. C.; Tewari, N.; Verma, S. S.; Tripathi, R. P.; Kumar, M.; Shukla, P. K. J. Carbohydr. Chem. 2004, 23, 353-374.
-
(2004)
J. Carbohydr. Chem
, vol.23
, pp. 353-374
-
-
Mishra, R.C.1
Tewari, N.2
Verma, S.S.3
Tripathi, R.P.4
Kumar, M.5
Shukla, P.K.6
-
21
-
-
0033675037
-
-
(b) Zadroøna, I.; Kurkowska, J.; Kruszewska, H.; Makuch, I. Farmaco 2000, 55, 499-501.
-
(2000)
Farmaco
, vol.55
, pp. 499-501
-
-
Zadroøna, I.1
Kurkowska, J.2
Kruszewska, H.3
Makuch, I.4
-
22
-
-
34948891969
-
-
(c) Gaonkar, S. L.; Rai, K. M. L.; Prabhuswamy, B. Med. Chem. Res. 2007, 15, 407-417.
-
(2007)
Med. Chem. Res
, vol.15
, pp. 407-417
-
-
Gaonkar, S.L.1
Rai, K.M.L.2
Prabhuswamy, B.3
-
23
-
-
0028970008
-
-
Kwon, T.; Heiman, A. S.; Oriaku, E. T.; Yoon, K.; Lee, H. J. J. Med. Chem. 1995, 38, 1048-1051.
-
(1995)
J. Med. Chem
, vol.38
, pp. 1048-1051
-
-
Kwon, T.1
Heiman, A.S.2
Oriaku, E.T.3
Yoon, K.4
Lee, H.J.5
-
24
-
-
32144438852
-
-
The authors of this paper indicate that the identification of isoxazoline antedrug metabolites are, at this point, undetermined
-
(b) Park, K.-K.; Ko, D.-H.; You, Z.; Khan, M. O. F.; Lee, H. J. Steroids 2006, 71, 183-188, The authors of this paper indicate that the identification of isoxazoline antedrug metabolites are, at this point, undetermined.
-
(2006)
Steroids
, vol.71
, pp. 183-188
-
-
Park, K.-K.1
Ko, D.-H.2
You, Z.3
Khan, M.O.F.4
Lee, H.J.5
-
25
-
-
49049092076
-
-
Pilkington, B. L.; Russell, S. E.; Whittle, A. J.; Mound, W. R.; Turnbull, M. D.; Kozakiewicz, A. M.; Hughes, D. J.; Whittingham, W. G. Preparation of imidazoline-5-ones as agrochemical fungicides. U.K. Patent Appl. GB 2327676 A 19990203, 1999.
-
Pilkington, B. L.; Russell, S. E.; Whittle, A. J.; Mound, W. R.; Turnbull, M. D.; Kozakiewicz, A. M.; Hughes, D. J.; Whittingham, W. G. Preparation of imidazoline-5-ones as agrochemical fungicides. U.K. Patent Appl. GB 2327676 A 19990203, 1999.
-
-
-
-
26
-
-
49049120051
-
-
Pasteris, R. J.; Hanagan, M. A.; Shapiro, R. Fungicidal azocyclic amides. PCT Int. Appl. WO 2008/013925 A2, 2008.
-
Pasteris, R. J.; Hanagan, M. A.; Shapiro, R. Fungicidal azocyclic amides. PCT Int. Appl. WO 2008/013925 A2, 2008.
-
-
-
-
28
-
-
49049097229
-
-
Costea, L.; Oniga, O.; Ionescu, M.; Tiperciuc, B.; Ghiran, D. Farmacia 2005, 53, 67-75.
-
(2005)
Farmacia
, vol.53
, pp. 67-75
-
-
Costea, L.1
Oniga, O.2
Ionescu, M.3
Tiperciuc, B.4
Ghiran, D.5
-
29
-
-
49049089086
-
-
(b) Preda, L.; Oniga, O.; Tiperciuc, B.; Verite, P.; Crisan, O.; Ghiran, D. Farmacia 2003, 51, 65-71.
-
(2003)
Farmacia
, vol.51
, pp. 65-71
-
-
Preda, L.1
Oniga, O.2
Tiperciuc, B.3
Verite, P.4
Crisan, O.5
Ghiran, D.6
-
30
-
-
0025369098
-
-
(c) Singh, S. P.; Sehgal, S.; Sharma, P. K. Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 1990, 29B, 533-538.
-
(1990)
Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem
, vol.29 B
, pp. 533-538
-
-
Singh, S.P.1
Sehgal, S.2
Sharma, P.K.3
-
31
-
-
33748734270
-
-
Varma, R. S.; Kumar, D.; Liesen, P. J. J. Chem. Soc., Perkin Trans. 1 1998, 24, 4093-4096.
-
(1998)
J. Chem. Soc., Perkin Trans. 1
, vol.24
, pp. 4093-4096
-
-
Varma, R.S.1
Kumar, D.2
Liesen, P.J.3
-
32
-
-
0012710353
-
-
Öhler, E.; El-Badawi, M.; Zbiral, E. Chem. Ber. 1985, 118, 4099-4130.
-
(1985)
Chem. Ber
, vol.118
, pp. 4099-4130
-
-
Öhler, E.1
El-Badawi, M.2
Zbiral, E.3
-
33
-
-
33846563007
-
-
For a related transformation, see
-
For a related transformation, see: Dixon, S. M.; Milinkevich, K. A.; Fujii, J.; Liu, R.; Yao, N.; Lam, K. S.; Kurth, M. J. J. Comb. Chem. 2007, 9, 143-157.
-
(2007)
J. Comb. Chem
, vol.9
, pp. 143-157
-
-
Dixon, S.M.1
Milinkevich, K.A.2
Fujii, J.3
Liu, R.4
Yao, N.5
Lam, K.S.6
Kurth, M.J.7
-
34
-
-
21744456872
-
-
Master, H. E.; Khan, S. I.; Poojari, K. A. Bioorg. Med. Chem. 2005, 13, 4891-4899.
-
(2005)
Bioorg. Med. Chem
, vol.13
, pp. 4891-4899
-
-
Master, H.E.1
Khan, S.I.2
Poojari, K.A.3
-
35
-
-
57249107792
-
-
(b) Kad, G. L.; Bhandari, M.; Kaur, J.; Rathee, R.; Singh, J. Green Chem. 2001, 3, 275-277.
-
(2001)
Green Chem
, vol.3
, pp. 275-277
-
-
Kad, G.L.1
Bhandari, M.2
Kaur, J.3
Rathee, R.4
Singh, J.5
-
36
-
-
0035811450
-
-
(c) Simoni, D.; Roberti, M.; Invidiata, F. P.; Rondanin, R.; Baruchello, R.; Malagutti, C.; Mazzali, A.; Rossi, M.; Grimaudo, S.; Capone, F.; Dusonchet, L.; Meli, M.; Raimondi, M. V.; Landino, M.; D'Alessandro, N.; Tolomeo, M.; Arindam, D.; Lu, S.; Benbrook, D. M. J. Med. Chem. 2001, 44, 2308-2318.
-
(2001)
J. Med. Chem
, vol.44
, pp. 2308-2318
-
-
Simoni, D.1
Roberti, M.2
Invidiata, F.P.3
Rondanin, R.4
Baruchello, R.5
Malagutti, C.6
Mazzali, A.7
Rossi, M.8
Grimaudo, S.9
Capone, F.10
Dusonchet, L.11
Meli, M.12
Raimondi, M.V.13
Landino, M.14
D'Alessandro, N.15
Tolomeo, M.16
Arindam, D.17
Lu, S.18
Benbrook, D.M.19
-
38
-
-
0030962376
-
-
(e) Zhang, L.; Chung, J. C.; Costello, T. D.; Valvis, I.; Ma, P.; Kauffman, S.; Ward, R. J. Org. Chem. 1997, 62, 2466-2470.
-
(1997)
J. Org. Chem
, vol.62
, pp. 2466-2470
-
-
Zhang, L.1
Chung, J.C.2
Costello, T.D.3
Valvis, I.4
Ma, P.5
Kauffman, S.6
Ward, R.7
-
39
-
-
33845358503
-
-
(f) Yano, J. K.; Denton, T. T.; Cerny, M. A.; Zhang, X.; Johnson, E. F.; Cashman, J. R. J. Med. Chem. 2006, 49, 6987-7001.
-
(2006)
J. Med. Chem
, vol.49
, pp. 6987-7001
-
-
Yano, J.K.1
Denton, T.T.2
Cerny, M.A.3
Zhang, X.4
Johnson, E.F.5
Cashman, J.R.6
-
40
-
-
0000699576
-
-
Lee, G. A. Synthesis 1982, 6, 508-509.
-
(1982)
Synthesis
, vol.6
, pp. 508-509
-
-
Lee, G.A.1
-
42
-
-
33847404358
-
-
For recent examples, see ref 15, as well as Bruncko, M, Oost, T. K, Belli, B. A, Ding, H, Joseph, M. K, Kunzer, A, Martineau, D, McClellan, W. J, Mitten, M, Ng, S.-C, Nimmer, P. M, Oltersdorf, T, Park, C.-M, Petras, A. M, Shoemaker, A. R, Song, X, Wang, X, Wendt, M. D, Zhang, H, Fesik, S. W, Rosenberg, S. H, Elmore, S. W. J. Med. Chem. 2007, 50, 641-662
-
For recent examples, see ref 15, as well as Bruncko, M.; Oost, T. K.; Belli, B. A.; Ding, H.; Joseph, M. K.; Kunzer, A.; Martineau, D.; McClellan, W. J.; Mitten, M.; Ng, S.-C.; Nimmer, P. M.; Oltersdorf, T.; Park, C.-M.; Petras, A. M.; Shoemaker, A. R.; Song, X.; Wang, X.; Wendt, M. D.; Zhang, H.; Fesik, S. W.; Rosenberg, S. H.; Elmore, S. W. J. Med. Chem. 2007, 50, 641-662.
-
-
-
-
43
-
-
33845284816
-
-
(b) Xu, J.; Wang, J.; Ellis, E. D.; Hamme, A. T., II Synthesis 2006, 22, 3815-3818.
-
(2006)
Synthesis
, vol.22
, pp. 3815-3818
-
-
Xu, J.1
Wang, J.2
Ellis, E.D.3
Hamme II, A.T.4
-
44
-
-
33750059496
-
-
(c) Beccalli, E. M.; Broggini, G.; Martinelli, M.; Masciocchi, N.; Sottocornola, S. Org. Lett. 2006, 8, 4521-4524.
-
(2006)
Org. Lett
, vol.8
, pp. 4521-4524
-
-
Beccalli, E.M.1
Broggini, G.2
Martinelli, M.3
Masciocchi, N.4
Sottocornola, S.5
-
45
-
-
33751314587
-
-
Barr, L.; Lincoln, S. F.; Easton, C. J. Chem. - Eur. J. 2006, 12, 8571-8580.
-
(2006)
Chem. - Eur. J
, vol.12
, pp. 8571-8580
-
-
Barr, L.1
Lincoln, S.F.2
Easton, C.J.3
-
46
-
-
49049120448
-
-
See Supporting Information for computed proton NMR chemical shift values for the 5,5- and 4,4-disubstitued isoxazoline regioisomers
-
(b) See Supporting Information for computed proton NMR chemical shift values for the 5,5- and 4,4-disubstitued isoxazoline regioisomers.
-
-
-
|