-
2
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E., Nguyen B., Havstad S., et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345 (2001) 1368
-
(2001)
N Engl J Med
, vol.345
, pp. 1368
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
-
3
-
-
27144553471
-
The microcirculation is the motor of sepsis
-
Ince C. The microcirculation is the motor of sepsis. Crit Care 9 (2005) S13
-
(2005)
Crit Care
, vol.9
-
-
Ince, C.1
-
4
-
-
4444233598
-
Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock
-
Sakr Y., Dubois M.J., De Backer D., et al. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 32 (2004) 1825
-
(2004)
Crit Care Med
, vol.32
, pp. 1825
-
-
Sakr, Y.1
Dubois, M.J.2
De Backer, D.3
-
5
-
-
0036039753
-
Opening the microcirculation: Can vasodilators be useful in sepsis?
-
Buwalda M., and Ince C. Opening the microcirculation: Can vasodilators be useful in sepsis?. Intensive Care Med 28 (2002) 1208
-
(2002)
Intensive Care Med
, vol.28
, pp. 1208
-
-
Buwalda, M.1
Ince, C.2
-
6
-
-
0033796625
-
Dynamic study of the distribution of microcirculatory blood flow in multiple splanchnic organs in septic shock
-
Hiltebrand L.B., Krejci V., Banic A., et al. Dynamic study of the distribution of microcirculatory blood flow in multiple splanchnic organs in septic shock. Crit Care Med 28 (2000) 3233
-
(2000)
Crit Care Med
, vol.28
, pp. 3233
-
-
Hiltebrand, L.B.1
Krejci, V.2
Banic, A.3
-
7
-
-
0029792273
-
Splanchnic ischemia and gut mucosal injury in sepsis and the multiple organ dysfunction syndrome
-
Pastores S.M., Katz D.P., and Kvetan V. Splanchnic ischemia and gut mucosal injury in sepsis and the multiple organ dysfunction syndrome. Am J Gastroenterol 91 (1996) 1697
-
(1996)
Am J Gastroenterol
, vol.91
, pp. 1697
-
-
Pastores, S.M.1
Katz, D.P.2
Kvetan, V.3
-
8
-
-
23744461829
-
Intraoperative splanchnic hypoperfusion, increased intestinal permeability, down-regulation of monocyte class II major histocompatibility complex expression, exaggerated acute phase response, and sepsis
-
Holland J., Carey M., Hughes N., et al. Intraoperative splanchnic hypoperfusion, increased intestinal permeability, down-regulation of monocyte class II major histocompatibility complex expression, exaggerated acute phase response, and sepsis. Am J Surg 190 (2005) 393
-
(2005)
Am J Surg
, vol.190
, pp. 393
-
-
Holland, J.1
Carey, M.2
Hughes, N.3
-
9
-
-
0028333046
-
Clearance of circulating endothelin-1 by ETB receptors in rats
-
Fukuroda T., Fujikawa T., Ozaki S., et al. Clearance of circulating endothelin-1 by ETB receptors in rats. Biochem Biophys Res Commun 199 (1994) 1461
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 1461
-
-
Fukuroda, T.1
Fujikawa, T.2
Ozaki, S.3
-
10
-
-
0025904585
-
Elevated plasma levels of endothelin in patients with sepsis syndrome
-
Weitzberg E., Lundberg J.M., and Rudehill A. Elevated plasma levels of endothelin in patients with sepsis syndrome. Circ Shock 33 (1991) 222
-
(1991)
Circ Shock
, vol.33
, pp. 222
-
-
Weitzberg, E.1
Lundberg, J.M.2
Rudehill, A.3
-
11
-
-
16044366592
-
Roles of ET-1 in endotoxin-induced microcirculatory disturbance in rat small intestine
-
Miura S., Fukumura D., Kurose I., et al. Roles of ET-1 in endotoxin-induced microcirculatory disturbance in rat small intestine. Am J Physiol 271 (1996) G461
-
(1996)
Am J Physiol
, vol.271
-
-
Miura, S.1
Fukumura, D.2
Kurose, I.3
-
12
-
-
0031840653
-
The endothelin receptor antagonist bosentan restores gut oxygen delivery and reverses intestinal mucosal acidosis in porcine endotoxin shock
-
Oldner A., Wanecek M., Goiny M., et al. The endothelin receptor antagonist bosentan restores gut oxygen delivery and reverses intestinal mucosal acidosis in porcine endotoxin shock. Gut 42 (1998) 696
-
(1998)
Gut
, vol.42
, pp. 696
-
-
Oldner, A.1
Wanecek, M.2
Goiny, M.3
-
13
-
-
0027423335
-
Endothelins mediate intestinal hypoperfusion during bacteremia
-
Wilson M.A., Steeb G.D., and Garrison R.N. Endothelins mediate intestinal hypoperfusion during bacteremia. J Surg Res 55 (1993) 168
-
(1993)
J Surg Res
, vol.55
, pp. 168
-
-
Wilson, M.A.1
Steeb, G.D.2
Garrison, R.N.3
-
14
-
-
0032766706
-
Pharmacology of tezosentan, new endothelin receptor antagonist designed for parenteral use
-
Clozel M., Ramuz H., Clozel J.P., et al. Pharmacology of tezosentan, new endothelin receptor antagonist designed for parenteral use. J Pharmacol Exp Ther 290 (1999) 840
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 840
-
-
Clozel, M.1
Ramuz, H.2
Clozel, J.P.3
-
15
-
-
2442557223
-
Differentiated and dose-related cardiovascular effects of a dual endothelin receptor antagonist in endotoxin shock
-
Konrad D., Oldner A., Rossi P., et al. Differentiated and dose-related cardiovascular effects of a dual endothelin receptor antagonist in endotoxin shock. Crit Care Med 32 (2004) 1192
-
(2004)
Crit Care Med
, vol.32
, pp. 1192
-
-
Konrad, D.1
Oldner, A.2
Rossi, P.3
-
16
-
-
34447305776
-
Effects of the dual endothelin receptor antagonist tezosentan and hypertonic saline/dextran on porcine endotoxin shock
-
Somell A., Weitzberg E., Suneson A., et al. Effects of the dual endothelin receptor antagonist tezosentan and hypertonic saline/dextran on porcine endotoxin shock. Acta Physiol (Oxf) 190 (2007) 291
-
(2007)
Acta Physiol (Oxf)
, vol.190
, pp. 291
-
-
Somell, A.1
Weitzberg, E.2
Suneson, A.3
-
17
-
-
16644392866
-
Tezosentan counteracts endotoxin-induced pulmonary edema and improves gas exchange
-
Rossi P., Wanecek M., Konrad D., et al. Tezosentan counteracts endotoxin-induced pulmonary edema and improves gas exchange. Shock 21 (2004) 543
-
(2004)
Shock
, vol.21
, pp. 543
-
-
Rossi, P.1
Wanecek, M.2
Konrad, D.3
-
18
-
-
20444388435
-
Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase C
-
Kuklin V., Kirov M., Sovershaev M., et al. Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase C. Crit Care 9 (2005) R211
-
(2005)
Crit Care
, vol.9
-
-
Kuklin, V.1
Kirov, M.2
Sovershaev, M.3
-
19
-
-
0036185717
-
Effects of tezosentan, a dual endothelin receptor antagonist, on the cardiovascular and renal systems of neonatal piglets during endotoxic shock
-
Chin A., Radhakrishnan J., Fornell L., et al. Effects of tezosentan, a dual endothelin receptor antagonist, on the cardiovascular and renal systems of neonatal piglets during endotoxic shock. J Pediatr Surg 37 (2002) 482
-
(2002)
J Pediatr Surg
, vol.37
, pp. 482
-
-
Chin, A.1
Radhakrishnan, J.2
Fornell, L.3
-
20
-
-
0037253077
-
Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock
-
Krejci V., Hiltebrand L.B., Erni D., et al. Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock. Crit Care Med 31 (2003) 203
-
(2003)
Crit Care Med
, vol.31
, pp. 203
-
-
Krejci, V.1
Hiltebrand, L.B.2
Erni, D.3
-
21
-
-
9344219968
-
Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic rats
-
Urbanowicz W., Sogni P., Moreau R., et al. Tezosentan, an endothelin receptor antagonist, limits liver injury in endotoxin challenged cirrhotic rats. Gut 53 (2004) 1844
-
(2004)
Gut
, vol.53
, pp. 1844
-
-
Urbanowicz, W.1
Sogni, P.2
Moreau, R.3
-
22
-
-
0022487050
-
Evaluation of laser-Doppler flowmetry as a measure of tissue blood flow
-
Smits G.J., Roman R.J., and Lombard J.H. Evaluation of laser-Doppler flowmetry as a measure of tissue blood flow. J Appl Physiol 61 (1986) 666
-
(1986)
J Appl Physiol
, vol.61
, pp. 666
-
-
Smits, G.J.1
Roman, R.J.2
Lombard, J.H.3
-
23
-
-
0032790980
-
Principles and practice of the laser-Doppler perfusion technique
-
Leahy M.J., de Mul F.F., Nilsson G.E., et al. Principles and practice of the laser-Doppler perfusion technique. Technol Health Care 7 (1999) 143
-
(1999)
Technol Health Care
, vol.7
, pp. 143
-
-
Leahy, M.J.1
de Mul, F.F.2
Nilsson, G.E.3
-
24
-
-
0026086481
-
Biochemical and functional characterization of endothelin peptides with special reference to vascular effects
-
Hemsen A. Biochemical and functional characterization of endothelin peptides with special reference to vascular effects. Acta Physiol Scand 602 Suppl (1991) 1
-
(1991)
Acta Physiol Scand
, vol.602
, Issue.SUPPL
, pp. 1
-
-
Hemsen, A.1
-
25
-
-
31344453457
-
The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects
-
De Backer D., Creteur J., Dubois M.J., et al. The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects. Crit Care Med 34 (2006) 403
-
(2006)
Crit Care Med
, vol.34
, pp. 403
-
-
De Backer, D.1
Creteur, J.2
Dubois, M.J.3
-
26
-
-
34247171377
-
Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis
-
Boerma E.C., van der Voort P.H., Spronk P.E., et al. Relationship between sublingual and intestinal microcirculatory perfusion in patients with abdominal sepsis. Crit Care Med 35 (2007) 1055
-
(2007)
Crit Care Med
, vol.35
, pp. 1055
-
-
Boerma, E.C.1
van der Voort, P.H.2
Spronk, P.E.3
-
28
-
-
0032801699
-
Differentiated effects on splanchnic homeostasis by selective and non-selective endothelin receptor antagonism in porcine endotoxaemia
-
Oldner A., Wanecek M., Weitzberg E., et al. Differentiated effects on splanchnic homeostasis by selective and non-selective endothelin receptor antagonism in porcine endotoxaemia. Br J Pharmacol 127 (1999) 1793
-
(1999)
Br J Pharmacol
, vol.127
, pp. 1793
-
-
Oldner, A.1
Wanecek, M.2
Weitzberg, E.3
-
29
-
-
0032013150
-
Endothelin (ET)-1 induced mucosal damage in the rat small intestine: Role of ET(A) receptors
-
Massberg S., Boros M., Leiderer R., et al. Endothelin (ET)-1 induced mucosal damage in the rat small intestine: Role of ET(A) receptors. Shock 9 (1998) 177
-
(1998)
Shock
, vol.9
, pp. 177
-
-
Massberg, S.1
Boros, M.2
Leiderer, R.3
-
30
-
-
0031962181
-
Endothelin 1 induces leukocyte adhesion in submucosal venules of the rat small intestine
-
Boros M., Massberg S., Baranyi L., et al. Endothelin 1 induces leukocyte adhesion in submucosal venules of the rat small intestine. Gastroenterology 114 (1998) 103
-
(1998)
Gastroenterology
, vol.114
, pp. 103
-
-
Boros, M.1
Massberg, S.2
Baranyi, L.3
-
31
-
-
33846439016
-
Tezosentan reduces the microvascular filtration coefficient in isolated lungs from rats subjected to cecum ligation and puncture
-
Kuklin V., Sovershaev M., Andreasen T., et al. Tezosentan reduces the microvascular filtration coefficient in isolated lungs from rats subjected to cecum ligation and puncture. Crit Care 9 (2005) R677
-
(2005)
Crit Care
, vol.9
-
-
Kuklin, V.1
Sovershaev, M.2
Andreasen, T.3
-
32
-
-
0027471933
-
Endothelin-1-induced increases in microvascular permeability in isolated, perfused rat lungs requires leukocytes and plasma
-
Helset E., Kjaeve J., and Hauge A. Endothelin-1-induced increases in microvascular permeability in isolated, perfused rat lungs requires leukocytes and plasma. Circ Shock 39 (1993) 15
-
(1993)
Circ Shock
, vol.39
, pp. 15
-
-
Helset, E.1
Kjaeve, J.2
Hauge, A.3
-
33
-
-
0029948525
-
Endothelin-1 synthesis and receptor-mediated activity in porcine lymph vessels
-
Reeder L.B., and Ferguson M.K. Endothelin-1 synthesis and receptor-mediated activity in porcine lymph vessels. J Surg Res 63 (1996) 215
-
(1996)
J Surg Res
, vol.63
, pp. 215
-
-
Reeder, L.B.1
Ferguson, M.K.2
-
34
-
-
0031867470
-
Differential expression of inducible nitric oxide synthase messenger RNA along the longitudinal and crypt-villus axes of the intestine in endotoxemic rats
-
Morin M.J., Unno N., Hodin R.A., et al. Differential expression of inducible nitric oxide synthase messenger RNA along the longitudinal and crypt-villus axes of the intestine in endotoxemic rats. Crit Care Med 26 (1998) 1258
-
(1998)
Crit Care Med
, vol.26
, pp. 1258
-
-
Morin, M.J.1
Unno, N.2
Hodin, R.A.3
-
35
-
-
0029809991
-
Endotoxic shock alters distribution of blood flow within the intestinal wall
-
Revelly J.P., Ayuse T., Brienza N., et al. Endotoxic shock alters distribution of blood flow within the intestinal wall. Crit Care Med 24 (1996) 1345
-
(1996)
Crit Care Med
, vol.24
, pp. 1345
-
-
Revelly, J.P.1
Ayuse, T.2
Brienza, N.3
-
36
-
-
0032907841
-
Involvement of endothelin/nitric oxide balance in hepatic ischemia/reperfusion injury
-
Scommotau S., Uhlmann D., Loffler B.M., et al. Involvement of endothelin/nitric oxide balance in hepatic ischemia/reperfusion injury. Langenbecks Arch Surg 384 (1999) 65
-
(1999)
Langenbecks Arch Surg
, vol.384
, pp. 65
-
-
Scommotau, S.1
Uhlmann, D.2
Loffler, B.M.3
-
37
-
-
2142762360
-
Effects of dopamine, dobutamine, and dopexamine on microcirculatory blood flow in the gastrointestinal tract during sepsis and anesthesia
-
Hiltebrand L.B., Krejci V., and Sigurdsson G.H. Effects of dopamine, dobutamine, and dopexamine on microcirculatory blood flow in the gastrointestinal tract during sepsis and anesthesia. Anesthesiology 100 (2004) 1188
-
(2004)
Anesthesiology
, vol.100
, pp. 1188
-
-
Hiltebrand, L.B.1
Krejci, V.2
Sigurdsson, G.H.3
-
38
-
-
33750700881
-
A time-dependent balance between endothelins and nitric oxide regulating portal resistance after endotoxin
-
Pannen B.H., Bauer M., Zhang J.X., et al. A time-dependent balance between endothelins and nitric oxide regulating portal resistance after endotoxin. Am J Physiol 271 (1996) H1953
-
(1996)
Am J Physiol
, vol.271
-
-
Pannen, B.H.1
Bauer, M.2
Zhang, J.X.3
-
39
-
-
0036833386
-
Potentiated hepatic microcirculatory response to endothelin-1 during polymicrobial sepsis
-
Baveja R., Kresge N., Ashburn J.H., et al. Potentiated hepatic microcirculatory response to endothelin-1 during polymicrobial sepsis. Shock 18 (2002) 415
-
(2002)
Shock
, vol.18
, pp. 415
-
-
Baveja, R.1
Kresge, N.2
Ashburn, J.H.3
-
40
-
-
0028910029
-
Alternations in liver hemodynamics in an intact porcine model of endotoxin shock
-
Ayuse T., Brienza N., Revelly J.P., et al. Alternations in liver hemodynamics in an intact porcine model of endotoxin shock. Am J Physiol 268 (1995) H1106
-
(1995)
Am J Physiol
, vol.268
-
-
Ayuse, T.1
Brienza, N.2
Revelly, J.P.3
-
41
-
-
34447270217
-
Tezosentan attenuates organ injury and mesenteric blood flow decrease in endotoxemia and cecal ligation and puncture
-
Erdem A., Meltem Sevgili A., et al. Tezosentan attenuates organ injury and mesenteric blood flow decrease in endotoxemia and cecal ligation and puncture. J Surg Res 141 (2007) 211
-
(2007)
J Surg Res
, vol.141
, pp. 211
-
-
Erdem, A.1
Meltem Sevgili, A.2
-
42
-
-
10244260306
-
Functional link between ETB receptors and eNOS maintain tissue oxygenation in the normal liver
-
Paxian M., Keller S.A., Baveja R., et al. Functional link between ETB receptors and eNOS maintain tissue oxygenation in the normal liver. Microcirculation 11 (2004) 435
-
(2004)
Microcirculation
, vol.11
, pp. 435
-
-
Paxian, M.1
Keller, S.A.2
Baveja, R.3
-
43
-
-
33644795431
-
LPS inhibits endothelin-1-induced endothelial NOS activation in hepatic sinusoidal cells through a negative feedback involving caveolin-1
-
Kamoun W.S., Karaa A., Kresge N., et al. LPS inhibits endothelin-1-induced endothelial NOS activation in hepatic sinusoidal cells through a negative feedback involving caveolin-1. Hepatology 43 (2006) 182
-
(2006)
Hepatology
, vol.43
, pp. 182
-
-
Kamoun, W.S.1
Karaa, A.2
Kresge, N.3
-
46
-
-
33645102148
-
Sublingual capnometry tracks microcirculatory changes in septic patients
-
Creteur J., De Backer D., Sakr Y., et al. Sublingual capnometry tracks microcirculatory changes in septic patients. Intensive Care Med 32 (2006) 516
-
(2006)
Intensive Care Med
, vol.32
, pp. 516
-
-
Creteur, J.1
De Backer, D.2
Sakr, Y.3
-
47
-
-
0025942757
-
Increased glucose uptake by intestinal mucosa and muscularis in hypermetabolic sepsis
-
Lang C.H., Obih J.C., Bagby G.J., et al. Increased glucose uptake by intestinal mucosa and muscularis in hypermetabolic sepsis. Am J Physiol 261 (1991) G287
-
(1991)
Am J Physiol
, vol.261
-
-
Lang, C.H.1
Obih, J.C.2
Bagby, G.J.3
-
48
-
-
0036174522
-
Endotoxin-induced mitochondrial damage correlates with impaired respiratory activity
-
Crouser E.D., Julian M.W., Blaho D.V., et al. Endotoxin-induced mitochondrial damage correlates with impaired respiratory activity. Crit Care Med 30 (2002) 276
-
(2002)
Crit Care Med
, vol.30
, pp. 276
-
-
Crouser, E.D.1
Julian, M.W.2
Blaho, D.V.3
|