-
1
-
-
0024462104
-
Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain
-
Maekawa T, Sakura H, Kanei-Ishii C, Sudo T, Yoshimura T, Fujisawa J, Yoshida M, Ishii S. Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain. Embo J 1989; 8:2023-8.
-
(1989)
Embo J
, vol.8
, pp. 2023-2028
-
-
Maekawa, T.1
Sakura, H.2
Kanei-Ishii, C.3
Sudo, T.4
Yoshimura, T.5
Fujisawa, J.6
Yoshida, M.7
Ishii, S.8
-
2
-
-
0030007235
-
Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain
-
Li XY, Green MR. Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain. Genes Dev 1996; 10:517-27.
-
(1996)
Genes Dev
, vol.10
, pp. 517-527
-
-
Li, X.Y.1
Green, M.R.2
-
3
-
-
0028905076
-
Transcription factor ATF2 regulation by the JNK signal transduction pathway
-
Gupta S, Campbell D, Derijard B, Davis RJ. Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 1995; 267:389-93.
-
(1995)
Science
, vol.267
, pp. 389-393
-
-
Gupta, S.1
Campbell, D.2
Derijard, B.3
Davis, R.J.4
-
5
-
-
0029808748
-
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
-
Whitmarsh AJ, Davis RJ. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med 1996; 74:589-607.
-
(1996)
J Mol Med
, vol.74
, pp. 589-607
-
-
Whitmarsh, A.J.1
Davis, R.J.2
-
6
-
-
18444411948
-
Growth factors can activate ATF2 via a two-step mechanism: Phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38
-
Ouwens DM, de Ruiter ND, van der Zon GC, Carter AP, Schouten J, van der Burgt C, Kooistra K, Bos JL, Maassen JA, van Dam H. Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38. Embo J 2002; 21:3782-93.
-
(2002)
Embo J
, vol.21
, pp. 3782-3793
-
-
Ouwens, D.M.1
de Ruiter, N.D.2
van der Zon, G.C.3
Carter, A.P.4
Schouten, J.5
van der Burgt, C.6
Kooistra, K.7
Bos, J.L.8
Maassen, J.A.9
van Dam, H.10
-
7
-
-
35248898241
-
ATF2 on the double - activating transcription factor and DNA damage response protein
-
Bhoumik A, Lopez-Bergami P, Ronai Z. ATF2 on the double - activating transcription factor and DNA damage response protein. Pigment Cell Res 2007; 20:498-506.
-
(2007)
Pigment Cell Res
, vol.20
, pp. 498-506
-
-
Bhoumik, A.1
Lopez-Bergami, P.2
Ronai, Z.3
-
8
-
-
0025878233
-
Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity
-
Hai T, Curran T. Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc Natl Acad Sci USA 1991; 88:3720-4.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3720-3724
-
-
Hai, T.1
Curran, T.2
-
9
-
-
0028092929
-
Interaction of nuclear proteins with an AP-1/CRE-like promoter sequence in the human TNFalpha gene
-
Newell CL, Deisseroth AB, Lopez-Berestein G. Interaction of nuclear proteins with an AP-1/CRE-like promoter sequence in the human TNFalpha gene. J Leukoc Biol 1994; 56:27-35.
-
(1994)
J Leukoc Biol
, vol.56
, pp. 27-35
-
-
Newell, C.L.1
Deisseroth, A.B.2
Lopez-Berestein, G.3
-
10
-
-
0034725037
-
Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation
-
Fuchs SY, Tappin I, Ronai Z. Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation. J Biol Chem 2000; 275:12560-4.
-
(2000)
J Biol Chem
, vol.275
, pp. 12560-12564
-
-
Fuchs, S.Y.1
Tappin, I.2
Ronai, Z.3
-
11
-
-
33644853153
-
Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization
-
Liu H, Deng X, Shyu YJ, Li JJ, Taparowsky EJ, Hu CD. Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization. Embo J 2006; 25:1058-69.
-
(2006)
Embo J
, vol.25
, pp. 1058-1069
-
-
Liu, H.1
Deng, X.2
Shyu, Y.J.3
Li, J.J.4
Taparowsky, E.J.5
Hu, C.D.6
-
12
-
-
19444363740
-
ATM-dependent phosphorylation of ATF2 is required for the DNA damage response
-
Bhoumik A, Takahashi S, Breitweiser W, Shiloh Y, Jones N, Ronai Z. ATM-dependent phosphorylation of ATF2 is required for the DNA damage response. Mol Cell 2005; 18:577-87.
-
(2005)
Mol Cell
, vol.18
, pp. 577-587
-
-
Bhoumik, A.1
Takahashi, S.2
Breitweiser, W.3
Shiloh, Y.4
Jones, N.5
Ronai, Z.6
-
14
-
-
48849111940
-
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM
-
Sun Y, Jiang X, Chen S, Fernandes N, Price BD. A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM. Proc Natl Acad Sci USA 2008; 17605-14.
-
(2008)
Proc Natl Acad Sci USA
, pp. 17605-17614
-
-
Sun, Y.1
Jiang, X.2
Chen, S.3
Fernandes, N.4
Price, B.D.5
-
15
-
-
0346365379
-
Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival
-
Berger AJ, Kluger HM, Li N, Kielhorn E, Halaban R, Ronai Z, Rimm DL. Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival. Cancer Res 2003; 63:8103-7.
-
(2003)
Cancer Res
, vol.63
, pp. 8103-8107
-
-
Berger, A.J.1
Kluger, H.M.2
Li, N.3
Kielhorn, E.4
Halaban, R.5
Ronai, Z.6
Rimm, D.L.7
-
16
-
-
0036735367
-
An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis
-
Bhoumik A, Huang TG, Ivanov V, Gangi L, Qiao RF, Woo SL, Chen SH, Ronai Z. An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis. J Clin Invest 2002; 110:643-50.
-
(2002)
J Clin Invest
, vol.110
, pp. 643-650
-
-
Bhoumik, A.1
Huang, T.G.2
Ivanov, V.3
Gangi, L.4
Qiao, R.F.5
Woo, S.L.6
Chen, S.H.7
Ronai, Z.8
-
17
-
-
0035128195
-
Activating transcription factor 2-derived peptides alter resistance of human tumor cell lines to ultraviolet irradiation and chemical treatment
-
Bhoumik A, Ivanov V, Ronai Z. Activating transcription factor 2-derived peptides alter resistance of human tumor cell lines to ultraviolet irradiation and chemical treatment. Clin Cancer Res 2001; 7:331-42.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 331-342
-
-
Bhoumik, A.1
Ivanov, V.2
Ronai, Z.3
-
18
-
-
0031723586
-
Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo
-
Huguier S, Baguet J, Perez S, van Dam H, Castellazzi M. Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo. Mol Cell Biol 1998; 18:7020-9.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7020-7029
-
-
Huguier, S.1
Baguet, J.2
Perez, S.3
van Dam, H.4
Castellazzi, M.5
-
19
-
-
0035971496
-
Distinct roles of Jun: Fos and Jun: ATF dimers in oncogenesis
-
van Dam H, Castellazzi M. Distinct roles of Jun: Fos and Jun: ATF dimers in oncogenesis. Oncogene 2001; 20:2453-64.
-
(2001)
Oncogene
, vol.20
, pp. 2453-2464
-
-
van Dam, H.1
Castellazzi, M.2
-
20
-
-
8544259596
-
Inhibition of melanoma growth and metastasis by ATF2-derived peptides
-
Bhoumik A, Gangi L, Ronai Z. Inhibition of melanoma growth and metastasis by ATF2-derived peptides. Cancer Res 2004; 64:8222-30.
-
(2004)
Cancer Res
, vol.64
, pp. 8222-8230
-
-
Bhoumik, A.1
Gangi, L.2
Ronai, Z.3
-
21
-
-
0032576820
-
ATF2 confers radiation resistance to human melanoma cells
-
Ronai Z, Yang YM, Fuchs SY, Adler V, Sardana M, Herlyn M. ATF2 confers radiation resistance to human melanoma cells. Oncogene 1998; 16:523-31.
-
(1998)
Oncogene
, vol.16
, pp. 523-531
-
-
Ronai, Z.1
Yang, Y.M.2
Fuchs, S.Y.3
Adler, V.4
Sardana, M.5
Herlyn, M.6
-
22
-
-
1642447684
-
Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity
-
Bhoumik A, Jones N, Ronai Z. Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity. Proc Natl Acad Sci USA 2004; 101:4222-7.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4222-4227
-
-
Bhoumik, A.1
Jones, N.2
Ronai, Z.3
-
23
-
-
0037034199
-
Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1
-
Recio JA, Merlino G. Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1. Oncogene 2002; 21:1000-8.
-
(2002)
Oncogene
, vol.21
, pp. 1000-1008
-
-
Recio, J.A.1
Merlino, G.2
-
24
-
-
40749118426
-
Retinoic acid decreases ATF-2 phosphorylation and sensitizes melanoma cells to taxol-mediated growth inhibition
-
Huang Y, Minigh J, Miles S, Niles RM. Retinoic acid decreases ATF-2 phosphorylation and sensitizes melanoma cells to taxol-mediated growth inhibition. J Mol Signal 2008; 3:3.
-
(2008)
J Mol Signal
, vol.3
, pp. 3
-
-
Huang, Y.1
Minigh, J.2
Miles, S.3
Niles, R.M.4
-
25
-
-
33847223782
-
Reduced levels of ATF-2 predispose mice to mammary tumors
-
Maekawa T, Shinagawa T, Sano Y, Sakuma T, Nomura S, Nagasaki K, Miki Y, Saito-Ohara F, Inazawa J, Kohno T, Yokota J, Ishii S. Reduced levels of ATF-2 predispose mice to mammary tumors. Mol Cell Biol 2007; 27:1730-44.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1730-1744
-
-
Maekawa, T.1
Shinagawa, T.2
Sano, Y.3
Sakuma, T.4
Nomura, S.5
Nagasaki, K.6
Miki, Y.7
Saito-Ohara, F.8
Inazawa, J.9
Kohno, T.10
Yokota, J.11
Ishii, S.12
-
26
-
-
39149145109
-
ATF-2 controls transcription of Maspin and GADD45 alpha genes independently from p53 to suppress mammary tumors
-
Maekawa T, Sano Y, Shinagawa T, Rahman Z, Sakuma T, Nomura S, Licht JD, Ishii S. ATF-2 controls transcription of Maspin and GADD45 alpha genes independently from p53 to suppress mammary tumors. Oncogene 2008; 27:1045-54.
-
(2008)
Oncogene
, vol.27
, pp. 1045-1054
-
-
Maekawa, T.1
Sano, Y.2
Shinagawa, T.3
Rahman, Z.4
Sakuma, T.5
Nomura, S.6
Licht, J.D.7
Ishii, S.8
-
27
-
-
40349089638
-
Suppressor role of activating transcription factor 2 (ATF2) in skin cancer
-
Bhoumik A, Fichtman B, Derossi C, Breitwieser W, Kluger HM, Davis S, Subtil A, Meltzer P, Krajewski S, Jones N, Ronai Z. Suppressor role of activating transcription factor 2 (ATF2) in skin cancer. Proc Natl Acad Sci USA 2008; 105:1674-9.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 1674-1679
-
-
Bhoumik, A.1
Fichtman, B.2
Derossi, C.3
Breitwieser, W.4
Kluger, H.M.5
Davis, S.6
Subtil, A.7
Meltzer, P.8
Krajewski, S.9
Jones, N.10
Ronai, Z.11
-
28
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm JS, Schroeter EH, Schrijvers V, Wolfe MS, Ray WJ, Goate A, Kopan R. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature 1999; 398:518-22.
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
29
-
-
0037145062
-
Presenilin couples the paired phosphorylation of beta-catenin independent of axin: Implications for beta-catenin activation in tumorigenesis
-
Kang DE, Soriano S, Xia X, Eberhart CG, De Strooper B, Zheng H, Koo EH. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell 2002; 110:751-62.
-
(2002)
Cell
, vol.110
, pp. 751-762
-
-
Kang, D.E.1
Soriano, S.2
Xia, X.3
Eberhart, C.G.4
De Strooper, B.5
Zheng, H.6
Koo, E.H.7
-
30
-
-
0035845481
-
Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis
-
Xia X, Qian S, Soriano S, Wu Y, Fletcher AM, Wang XJ, Koo EH, Wu X, Zheng H. Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proc Natl Acad Sci USA 2001; 98:10863-8.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10863-10868
-
-
Xia, X.1
Qian, S.2
Soriano, S.3
Wu, Y.4
Fletcher, A.M.5
Wang, X.J.6
Koo, E.H.7
Wu, X.8
Zheng, H.9
-
31
-
-
0033545845
-
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
-
Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, Ben-Ze'ev A. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci USA 1999; 96:5522-7.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
Albanese, C.4
D'Amico, M.5
Pestell, R.6
Ben-Ze'ev, A.7
-
32
-
-
0033119801
-
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999; 398:422-6.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
33
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
Nicolas M, Wolfer A, Raj K, Kummer JA, Mill P, van Noort M, Hui CC, Clevers H, Dotto GP, Radtke F. Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 2003; 33:416-21.
-
(2003)
Nat Genet
, vol.33
, pp. 416-421
-
-
Nicolas, M.1
Wolfer, A.2
Raj, K.3
Kummer, J.A.4
Mill, P.5
van Noort, M.6
Hui, C.C.7
Clevers, H.8
Dotto, G.P.9
Radtke, F.10
-
34
-
-
0027288979
-
Overexpression of cyclin D1 in mouse skin carcinogenesis
-
Bianchi AB, Fischer SM, Robles AI, Rinchik EM, Conti CJ. Overexpression of cyclin D1 in mouse skin carcinogenesis. Oncogene 1993; 8:1127-33.
-
(1993)
Oncogene
, vol.8
, pp. 1127-1133
-
-
Bianchi, A.B.1
Fischer, S.M.2
Robles, A.I.3
Rinchik, E.M.4
Conti, C.J.5
-
35
-
-
35748940970
-
Presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway
-
Repetto E, Yoon IS, Zheng H, Kang DE. Presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway. J Biol Chem 2007; 282:31504-16.
-
(2007)
J Biol Chem
, vol.282
, pp. 31504-31516
-
-
Repetto, E.1
Yoon, I.S.2
Zheng, H.3
Kang, D.E.4
-
36
-
-
0032529165
-
Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
-
Robles AI, Rodriguez-Puebla ML, Glick AB, Trempus C, Hansen L, Sicinski P, Tennant RW, Weinberg RA, Yuspa SH, Conti CJ. Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo. Genes Dev 1998; 12:2469-74.
-
(1998)
Genes Dev
, vol.12
, pp. 2469-2474
-
-
Robles, A.I.1
Rodriguez-Puebla, M.L.2
Glick, A.B.3
Trempus, C.4
Hansen, L.5
Sicinski, P.6
Tennant, R.W.7
Weinberg, R.A.8
Yuspa, S.H.9
Conti, C.J.10
-
37
-
-
34547539177
-
Presenilin/gamma- secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression
-
Zhang YW, Wang R, Liu Q, Zhang H, Liao FF, Xu H. Presenilin/gamma- secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression. Proc Natl Acad Sci USA 2007; 104:10613-8.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 10613-10618
-
-
Zhang, Y.W.1
Wang, R.2
Liu, Q.3
Zhang, H.4
Liao, F.F.5
Xu, H.6
-
38
-
-
9244240316
-
Overexpression of activating transcription factor-2 is required for tumor growth and progression in mouse skin tumors
-
Papassava P, Gorgoulis VG, Papaevangeliou D, Vlahopoulos S, van Dam H, Zoumpourlis V. Overexpression of activating transcription factor-2 is required for tumor growth and progression in mouse skin tumors. Cancer Res 2004; 64:8573-84.
-
(2004)
Cancer Res
, vol.64
, pp. 8573-8584
-
-
Papassava, P.1
Gorgoulis, V.G.2
Papaevangeliou, D.3
Vlahopoulos, S.4
van Dam, H.5
Zoumpourlis, V.6
-
39
-
-
0026642195
-
Induction of apoptosis in fibroblasts by c-myc protein
-
Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ, Hancock DC. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992; 69:119-28.
-
(1992)
Cell
, vol.69
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
Waters, C.M.7
Penn, L.Z.8
Hancock, D.C.9
-
41
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
-
Radtke F, Raj K. The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer 2003; 3:756-67.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
42
-
-
0033536072
-
Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations
-
Song W, Nadeau P, Yuan M, Yang X, Shen J, Yankner BA. Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations. Proc Natl Acad Sci USA 1999; 96:6959-63.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6959-6963
-
-
Song, W.1
Nadeau, P.2
Yuan, M.3
Yang, X.4
Shen, J.5
Yankner, B.A.6
-
43
-
-
38349047019
-
ETS transcription factors: Oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer
-
Turner DP, Watson DK. ETS transcription factors: oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer. Expert Rev Anticancer Ther 2008; 8:33-42.
-
(2008)
Expert Rev Anticancer Ther
, vol.8
, pp. 33-42
-
-
Turner, D.P.1
Watson, D.K.2
|