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Volumn 1, Issue 19, 2008, Pages

TCR triggering by the pMHC complex: Valency, affinity, and dynamics

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 48849110994     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/stke.119pe21     Document Type: Review
Times cited : (19)

References (37)
  • 2
    • 34447286463 scopus 로고    scopus 로고
    • Molecular mechanisms involved in T cell receptor triggering
    • K. Choudhuri, P. A. van der Merwe, Molecular mechanisms involved in T cell receptor triggering. Semin. Immunol. 19, 255-261 (2007).
    • (2007) Semin. Immunol , vol.19 , pp. 255-261
    • Choudhuri, K.1    Van Der Merwe, P.A.2
  • 3
    • 32244435875 scopus 로고    scopus 로고
    • Deconstructing the form and function of the TCR/CD3 complex
    • M. S. Kuhns, M. M. Davis, K. C. Garcia, Deconstructing the form and function of the TCR/CD3 complex. Immunity 24, 133-139 (2006).
    • (2006) Immunity , vol.24 , pp. 133-139
    • Kuhns, M.S.1    Davis, M.M.2    Garcia, K.C.3
  • 4
    • 14944346245 scopus 로고    scopus 로고
    • How T cells "see" antigen
    • M. Krogsgaard, M. M. Davis, How T cells "see" antigen. Nat. Immunol. 6, 239-245 (2005).
    • (2005) Nat. Immunol , vol.6 , pp. 239-245
    • Krogsgaard, M.1    Davis, M.M.2
  • 5
    • 0037188899 scopus 로고    scopus 로고
    • Recruitment of Nck by CD3ε reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation
    • D. Gil, W. W. Schamel, M. Montoya, F. Sanchez-Madrid, B. Alarcon, Recruitment of Nck by CD3ε reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Cell 109, 901-912 (2002).
    • (2002) Cell , vol.109 , pp. 901-912
    • Gil, D.1    Schamel, W.W.2    Montoya, M.3    Sanchez-Madrid, F.4    Alarcon, B.5
  • 7
    • 0029100015 scopus 로고
    • Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness
    • J. P. Abastado, Y. C. Lone, A. Casrouge, G. Boulot, P. Kourilsky, Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness. J. Exp. Med. 182, 439-447 (1995).
    • (1995) J. Exp. Med , vol.182 , pp. 439-447
    • Abastado, J.P.1    Lone, Y.C.2    Casrouge, A.3    Boulot, G.4    Kourilsky, P.5
  • 8
    • 0033575788 scopus 로고    scopus 로고
    • Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation
    • S. Casares, C. S. Zong, D. L. Radu, A. Miller, C. A. Bona, T. D. Brumeanu, Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation. J. Exp. Med. 190, 543-553 (1999).
    • (1999) J. Exp. Med , vol.190 , pp. 543-553
    • Casares, S.1    Zong, C.S.2    Radu, D.L.3    Miller, A.4    Bona, C.A.5    Brumeanu, T.D.6
  • 10
    • 0033710093 scopus 로고    scopus 로고
    • The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers
    • J. R. Cochran, T. O. Cameron, L. J. Stern, The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers. Immunity 12, 241-250 (2000).
    • (2000) Immunity , vol.12 , pp. 241-250
    • Cochran, J.R.1    Cameron, T.O.2    Stern, L.J.3
  • 11
    • 31144479383 scopus 로고    scopus 로고
    • CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement
    • J. D. Stone, L. J. Stern, CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement. J. Immunol. 176, 1498-1505 (2006).
    • (2006) J. Immunol , vol.176 , pp. 1498-1505
    • Stone, J.D.1    Stern, L.J.2
  • 13
    • 15044358353 scopus 로고    scopus 로고
    • Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
    • M. Krogsgaard, Q. J. Li, C. Sumen, J. B. Huppa, M. Huse, M. M. Davis, Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity. Nature 434, 238-243 (2005).
    • (2005) Nature , vol.434 , pp. 238-243
    • Krogsgaard, M.1    Li, Q.J.2    Sumen, C.3    Huppa, J.B.4    Huse, M.5    Davis, M.M.6
  • 14
    • 0142134858 scopus 로고    scopus 로고
    • Supported planar bilayers in studies on immune cell adhesion and communication
    • J. T. Groves, M. L. Dustin, Supported planar bilayers in studies on immune cell adhesion and communication. J. Immunol. Methods 278, 19-32 (2003).
    • (2003) J. Immunol. Methods , vol.278 , pp. 19-32
    • Groves, J.T.1    Dustin, M.L.2
  • 15
    • 34447647655 scopus 로고    scopus 로고
    • Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist
    • M. Huse, L. O. Klein, A. T. Girvin, J. M. Faraj, Q. J. Li, M. S. Kuhns, M. M. Davis, Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist. Immunity 27, 76-88 (2007).
    • (2007) Immunity , vol.27 , pp. 76-88
    • Huse, M.1    Klein, L.O.2    Girvin, A.T.3    Faraj, J.M.4    Li, Q.J.5    Kuhns, M.S.6    Davis, M.M.7
  • 16
    • 40149108609 scopus 로고    scopus 로고
    • Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity
    • Z. Ma, K. A. Sharp, P. A. Janmey, T. H. Finkel, Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity. PLoS Biol. 6, e43 (2008).
    • (2008) PLoS Biol , vol.6
    • Ma, Z.1    Sharp, K.A.2    Janmey, P.A.3    Finkel, T.H.4
  • 17
    • 0034235794 scopus 로고    scopus 로고
    • Cutting edge: Hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation
    • S. K. Bromley, D. A. Peterson, M. D. Gunn, M. L. Dustin, Cutting edge: Hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation. J. Immunol. 165, 15-19 (2000).
    • (2000) J. Immunol , vol.165 , pp. 15-19
    • Bromley, S.K.1    Peterson, D.A.2    Gunn, M.D.3    Dustin, M.L.4
  • 20
    • 4143146469 scopus 로고    scopus 로고
    • T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation
    • C. Sumen, M. L. Dustin, M. M. Davis, T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation. J. Cell Biol. 166, 579-590 (2004).
    • (2004) J. Cell Biol , vol.166 , pp. 579-590
    • Sumen, C.1    Dustin, M.L.2    Davis, M.M.3
  • 22
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • C. R. Monks, B. A. Freiberg, H. Kupfer, N. Sciaky, A. Kupfer, Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86 (1998).
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 23
    • 27544441784 scopus 로고    scopus 로고
    • Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
    • G. Campi, R. Varma, M. L. Dustin, Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J. Exp. Med. 202, 1031-1036 (2005).
    • (2005) J. Exp. Med , vol.202 , pp. 1031-1036
    • Campi, G.1    Varma, R.2    Dustin, M.L.3
  • 24
    • 0025286210 scopus 로고
    • Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation
    • C. V. Harding, E. R. Unanue, Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation. Nature 346, 574-576 (1990).
    • (1990) Nature , vol.346 , pp. 574-576
    • Harding, C.V.1    Unanue, E.R.2
  • 25
    • 0031458442 scopus 로고    scopus 로고
    • The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells
    • K. Kimachi, M. Croft, H. M. Grey, The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells. Eur. J. Immunol. 27, 3310-3317 (1997)
    • (1997) Eur. J. Immunol , vol.27 , pp. 3310-3317
    • Kimachi, K.1    Croft, M.2    Grey, H.M.3
  • 26
    • 0034041461 scopus 로고    scopus 로고
    • Determination of the relationship between T cell responsiveness and the number of MHC-peptide complexes using specific monoclonal antibodies
    • P. A. Reay, K. Matsui, K. Haase, C. Wulfing, Y. H. Chien, M. M. Davis, Determination of the relationship between T cell responsiveness and the number of MHC-peptide complexes using specific monoclonal antibodies. J. Immunol. 164, 5626-5634 (2000).
    • (2000) J. Immunol , vol.164 , pp. 5626-5634
    • Reay, P.A.1    Matsui, K.2    Haase, K.3    Wulfing, C.4    Chien, Y.H.5    Davis, M.M.6
  • 27
    • 33746011209 scopus 로고    scopus 로고
    • T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
    • R. Varma, G. Campi, T. Yokosuka, T. Saito, M. L. Dustin, T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 25, 117-127 (2006).
    • (2006) Immunity , vol.25 , pp. 117-127
    • Varma, R.1    Campi, G.2    Yokosuka, T.3    Saito, T.4    Dustin, M.L.5
  • 28
    • 0037167816 scopus 로고    scopus 로고
    • Direct observation of ligand recognition by T cells
    • D. J. Irvine, M. A. Purbhoo, M. Krogsgaard, M. M. Davis, Direct observation of ligand recognition by T cells. Nature 419, 845-849 (2002).
    • (2002) Nature , vol.419 , pp. 845-849
    • Irvine, D.J.1    Purbhoo, M.A.2    Krogsgaard, M.3    Davis, M.M.4
  • 29
    • 0037452755 scopus 로고    scopus 로고
    • T-cell activation: The power of one
    • R. N. Germain, T-cell activation: The power of one. Curr. Biol. 13, R137-R139 (2003).
    • (2003) Curr. Biol , vol.13
    • Germain, R.N.1
  • 31
    • 0031868557 scopus 로고    scopus 로고
    • Toward a predictive understanding of molecular recognition
    • Z. Weng, C. Delisi, Toward a predictive understanding of molecular recognition. Immunol. Rev. 163, 251-266 (1998).
    • (1998) Immunol. Rev , vol.163 , pp. 251-266
    • Weng, Z.1    Delisi, C.2
  • 32
    • 0020606611 scopus 로고
    • Membrane fluidity and the probability of complement fixation
    • C. Delisi, F.W. Wiegel, Membrane fluidity and the probability of complement fixation. J. Theor. Biol. 102, 307-322 (1983).
    • (1983) J. Theor. Biol , vol.102 , pp. 307-322
    • Delisi, C.1    Wiegel, F.W.2
  • 33
    • 42049101786 scopus 로고    scopus 로고
    • The receptor deformation model of TCR triggering
    • Z. Ma, P. A. Janmey, T. H. Finkel, The receptor deformation model of TCR triggering. FASEB J. 22, 1002-1008 (2008).
    • (2008) FASEB J , vol.22 , pp. 1002-1008
    • Ma, Z.1    Janmey, P.A.2    Finkel, T.H.3
  • 34
    • 0034232037 scopus 로고    scopus 로고
    • The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
    • M. L. Dustin, J. A. Cooper, The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling. Nat. Immunol. 1, 23-29 (2000).
    • (2000) Nat. Immunol , vol.1 , pp. 23-29
    • Dustin, M.L.1    Cooper, J.A.2
  • 35
  • 36
    • 0029809142 scopus 로고    scopus 로고
    • Normal T cells express two T cell antigen receptor populations, one of which is linked to the cytoskeleton via ζ chain and displays a unique activation-dependent phosphorylation pattern
    • S. Caplan, M. Baniyash, Normal T cells express two T cell antigen receptor populations, one of which is linked to the cytoskeleton via ζ chain and displays a unique activation-dependent phosphorylation pattern. J. Biol. Chem. 271, 20705-20712 (1996).
    • (1996) J. Biol. Chem , vol.271 , pp. 20705-20712
    • Caplan, S.1    Baniyash, M.2
  • 37
    • 0028851581 scopus 로고
    • Tyrosine-phosphorylated T cell receptor ζ chain associates with the actin cytoskeleton upon activation of mature T lymphocytes
    • M. M. Rozdzial, B. Malissen, T. H. Finkel, Tyrosine-phosphorylated T cell receptor ζ chain associates with the actin cytoskeleton upon activation of mature T lymphocytes. Immunity 3, 623-633 (1995).
    • (1995) Immunity , vol.3 , pp. 623-633
    • Rozdzial, M.M.1    Malissen, B.2    Finkel, T.H.3


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