Effect of cranberry juice concentrate on chemically-induced urinary bladder cancers

Oncology Reports

Volumn 19, Issue 6, 2008, Pages 1565-1570

  Prasain, Jeevan K ^a   Jones, Kenneth ^a   Moore, Ray ^d   Barnes, Stephen ^a,d   Leahy, Marge ^e   Roderick, Robin ^e   Juliana, M Margaret ^b   Grubbs, Clinton J ^c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c Kentucky   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e Ocean Spray Cranberries Inc   (United States)

Author keywords

Cancer; Chemical carcinogen; Cranberry juice; Urinary bladder

Indexed keywords

CRANBERRY EXTRACT; N BUTYL N (4 HYDROXYBUTYL)NITROSAMINE; QUERCETIN; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CANCER; BLOOD SAMPLING; CHEMICAL COMPOSITION; CHEMICALLY INDUCED DISORDER; CONTROLLED STUDY; CRANBERRY JUICE; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; FISCHER 344 RAT; HISTOPATHOLOGY; LIQUID CHROMATOGRAPHY; LOW DRUG DOSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; URINALYSIS; ANIMAL; BLADDER TUMOR; CHEMISTRY; CRANBERRY; MASS SPECTROMETRY; PATHOLOGY; PHYTOTHERAPY; RAT;

ANIMALS; BUTYLHYDROXYBUTYLNITROSAMINE; CHROMATOGRAPHY, LIQUID; FEMALE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, INBRED F344; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; URINARY BLADDER NEOPLASMS; VACCINIUM MACROCARPON;

EID: 48849087451     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Wakai K, Takashi M, Okamura K, et al: Foods and nutrients in relation to bladder cancer risk: a case-control study in Aichi Prefecture, Central Japan. Nutr Cancer 38: 13-22, 2000.
2. Nagano J, Kong S, Preston DL, et al: Bladder-cancer incidence in relation to vegetable and fruit consumption: a prospective study of atomic-bomb survivors. Int J Cancer 86: 132-138, 2000.
3. Chen JJ, Ye ZQ and Koo MW: Growth inhibition and cell cycle arrest effects of epigallocatechin gallate in the NBT-II bladder tumour cell line. BJU Int 93: 1082-1086, 2004.
4. Kemberling JK, Hampton JA, Keck RW, Gomez MA and Selman SH: Inhibition of bladder tumor growth by the green tea derivative epigallocatechin-3-gallate. J Urol 170: 773-776, 2003.
5. Vinson JA, Su X, Zubik L and Bose P: Phenol antioxidant quantity and quality in foods: fruits. J Agric Food Chem 49: 5315-5321, 2001.
6. Howell AB and Foxman B: Cranberry juice and adhesion of antibiotic-resistent uropathogens. JAMA 287: 3082-3083, 2002.
7. Larocca LM, Giustacchini M, Maggiano N, et al: Growth-inhibitory effect of quercetin and presence of type II estrogen binding sites in primary human transitional cell carcinomas. J Urol 152: 1029-1033, 1994.
8. Hirose M, Fukushima S, Sakata T, Inui M and Ito N: Effect of quercetin on two-stage carcinogenesis of the rat urinary bladder. Cancer Lett 21: 23-27, 1983.
9. Seeram NP, Adams LS, Hardy ML and Heber D: Total cranberry extract versus its phytochemical constituents: antiproliferative and synergistic effects against human tumor cells. J Agric Food Chem 52: 2512-2517, 2004.
10. Grubbs CJ, Lubet RA, Koki AT, et al: Celecoxib inhibits N-butyl-N-(4-hydroxybutyl) -nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats. Cancer Res 60: 5599-5602, 2000.
11. Yan X, Murphy BT, Hammond GB, Vinson JA and Neto CC: Antioxidant activities and antitumor screening of extracts from cranberry fruit ( Vaccinium macrocarpon). J Agric Food Chem 50: 5844-5849, 2002.
12. Singleton VL and Rossi JA: Colorimetry of total phenolics with phosphomolydic-phosphotungstic acid reagents. Am J Enol Vitic 16: 144-158, 1965.
13. Prior RL, Wu X and Schaich K: Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements. J Agric Food Chem 53: 4290-4302, 2005.
14. McCormick DL, Ronan SS, Becci PJ and Moon RC: Influence of total dose and dose schedule on induction of urinary bladder cancer in the mouse by N-butyl-N-(4-hydroxybutyl)nitrosamine. Carcinogenesis 2: 251-254, 1981.
15. Becci PJ, Thompson HJ, Strum JM, Brown CC and Sporn MB: N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in C57BL/6 X DBA/2 F1 mice as a useful model for study of chemoprevention of cancer with retinoids. Cancer Res 41: 927-932, 1981.
16. Grubbs CJ, Moon RC, Squire RA, et al: 13-cis-Retinoic acid: inhibition of bladder carcinogenesis induced in rats by N-butyl-N-(4-hydroxybutyl) nitrosamine. Science 198: 743-744, 1977.
17. Lubet RA, Huebner K, Fong LYY, et al: 4-Hydroxybutyl-(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin. Carcinogenesis 26: 571-578, 2005.
18. Vinh PQ, Sugie S, Tanaka T, et al: Chemopreventive effects of a flavonoid antioxidant silymarin on N-butyl-N-(4-hydroxy-butyl) nitrosamine-induced urinary bladder carcinogenesis in male ICR mice. Jpn J Cancer Res 93: 42-49, 2002.
19. Okazaki K, Umemura T, Imazawa T, et al: Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl) nitrosamine in rats after initiation. Cancer Sci 94: 948-952, 2003.
20. Kandil FE, Smith MA, Rogers RB, et al: Composition of a chemopreventive proanthocyanidin-rich fraction from cranberry fruits responsible for the inhibition of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced ornithine decarboxylase (ODC) activity. J Agric Food Chem 50: 1063-1069, 2002.
21. Sun J, Chu YF, Wu X and Liu RH: Antioxidant and anti-proliferative activities of common fruits. J Agric and Food Chem 50: 7449-7454, 2002.
22. Guthrie N: Effect of cranberry juice and products on human breast cancer cell growth. Proc Exper Biology Conf 53: 13, 2000.
23. Rao KV, Detriac CJ, Steele VE, et al: Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder. Carcinogenesis 17: 1435-1438, 1996.
24. Moon RC, Kelloff GJ, Detriac CJ, et al: Chemoprevention of OH-BBN induced bladder cancer in mice by piroxicam. Carcinogenesis 14: 1487-1489, 1993.
25. Okajima E, Denda A, Ozono S, et al: Chemopreventive effects of nimesulide, a selective cyclooxygense-2 inhibitor, on the development of rat urinary bladder carcinomas initiated by N-butyl-N-(4-hydroxybutyl) nitrosamine. Cancer Res 58: 3028-3031, 1998.
26. Ariga T: The antioxidative function, preventive action on disease and utilization of proanthocyanidins. Biofactors 21: 197-201, 2004.
27. Valentova K, Stejskal D, Bednar P, et al: Biosafety, antioxidant status, and metabolities in urine after consumption of dried cranberry juice in healthy women: a pilot double-blind placebo-controlled trial. J Agric Food Chem 55: 3217-3224, 2007.
28. Roy S, Khanna S, Alessio HM, et al: Anti-angiogenic property of edible berries. Free Radic Res 36: 1023-1031, 2002.
29. Moon JH, Tsushida T, Nakahara K and Terao J: Identification of quercetin 3-O-beta-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin. Free Radic Biol Med 30: 1274-1285, 2001.
30. Wittig J, Herderich M, Graefe EU and Veit M: Identification of quercetin glucuronides in human plasma by high-performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Biomed Sci Appl 753: 237-243, 2001.
31. Graf BA, Mullen W, Caldwell ST, et al: Disposition and metabolism of [2-14C] quercetin-4′-glucoside in rats. Drug Metab Dispos 33: 1036-1043 2005.
32. Hong YJ and Mitchell AE: Metabolic profiling of flavonol metabolites in human urine by liquid chromatography and tandem mass spectrometry. J Agric Food Chem 52: 6794-6801, 2004.
33. Fabre N, Rustan I, de Hoffmann E and Quetin-Leclercq J: Determination of flavone, flavonol and flavanone aglycones by negative ion liquid chromatography electrospray ion trap mass spectrometry. J Am Soc Mass Spectrom. 12: 707-715, 2001.
34. Meng X, Maliakal P, Lu H, Lee MJ and Yang CS: Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice. J Agric Food Chem 52: 935-942, 2004.
35. de Vries JH, Hollman PC, van Amersfoort I, Olthof MR and Katan MB: Red wine is a poor source of bioavailable flavonols in men. J Nutr 131: 745-748, 2001.
36. Hollman PC, van Trijp JM, Buysman MN, et al: Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man. FEBS Lett 418: 52-156, 1997.