Growth inhibition and cell cycle arrest effects of epigallocatechin gallate in the NBT-II bladder tumour cell line

BJU International

Volumn 93, Issue 7, 2004, Pages 1082-1086

  Chen, J J ^a,b   Ye, Z Q ^b   Koo, M W L ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Bladder cancer; Cell cycle; Cyclin D1; Epigallocatechin gallate; Green tea

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; DNA; EPIGALLOCATECHIN GALLATE; POLYPHENOL; RETINOBLASTOMA PROTEIN; ANTINEOPLASTIC AGENT; CATECHIN; DRUG DERIVATIVE;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; BLADDER TUMOR; CANCER INHIBITION; CELL CULTURE; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; EVALUATION; FLOW CYTOMETRY; GROWTH INHIBITION; INCUBATION TIME; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TEA; TIME; TUMOR CELL LINE; WESTERN BLOTTING; ARTICLE; CELL DIVISION; DRUG SCREENING; HUMAN; METHODOLOGY; PATHOLOGY; PHYTOTHERAPY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMELLIA SINENSIS; CATECHIN; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; FLOW CYTOMETRY; HUMANS; PHYTOTHERAPY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; URINARY BLADDER NEOPLASMS;

EID: 2542511546     PISSN: 14644096     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2004.04785.x     Document Type: Conference Paper

References (24)

1. Yang CS, Landau JM, Huang MT, Newmark HL. Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu Rev Nutr 2001; 21: 381-406
2. National Cancer Institute DCPC. Chemoprevention Branch and Agent development Committee. Clinical development plan: tea extracts, green tea polyphenols, epigallocatechin gallate. J Cell Biochem 1996; 265: 236-57
3. Yang CS, Lee MJ, Chen L, Yang GY. Polyphenols as inhibitors of carcinogenesis. Environ Health Perspect 1997; 105 (Suppl 4): 971-6
4. Katiyar SK, Ahamad N, Mukhtar H. Green tea and skin. Arch Dermatol 2000; 136: 989-94
5. Kelsey JL, Cannon MD. Epidemiology of breast cancer. Epidermiol Rev 1990; 12: 228-40
6. Kathryn KT, Hafer LJ, Kim DW et al. Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture. J Cell Biochem 2001; 82: 387-98
7. Chen ZP, Schell JB, Ho CT, Chen KY. Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts. Cancer Lett 1998; 129: 173-9
8. Pianetti S, Guo SQ, Kavanagh KT, Sonenshein GE. Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/Neu signaling, proliferation, and transformed phenotype of breast cancer cells. Cancer Res 2002; 62: 652-5
9. Liang YC, Lin-shiau SY, Chen CF, Lin JK. Suppression of Extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin gallate in human A431 epidermoid carcinoma cells. J Cell Biochem 1997; 67: 55-65
10. Masuda M, Suzui M, Weinstein B. Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines. Clin Cancer Res 2001; 7: 4220-9
11. Ahmad N, Cheng P, Mukhtar H. Cell cycle dysregulation by green tea polyphenol epigallocatechin-3 gallate. Biochem Biophys Res Commun 2000; 275: 328-34
12. Gupta S, Hussain T, Mukhtar H. Molecular pathway for (-)- epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells. Arch Biochem Biophys 2003; 410: 177-85
13. Gupta S, Ahamad N, Nieminen AL, Mukhtar H. Growth inhibition, cell cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells. Toxicol Appl Pharmacol 2000; 164: 82-90
14. Schmidt BA, Rose A, Steinhoff C, Strohmeyer T, Hartmann M, Ackermann R. Up-regulation of cyclin-dependent kinase 4/cyclin D2 expression but down-regulation of cyclin-dependent kinase 2/cyclin E in testicular germ cell tumors. Cancer Res 2001; 61: 4214-21
15. Fradet Y. Recent advances in the management of superficial bladder tumors. Can J Urol 2002; 9: 1544-50
16. Sato D. Inhibition of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rats by green tea. Int J Urol 1999; 6: 93-9
17. Lee CCR, Fukushima S. Alterations in cyclin D1, P53, and the cell cycle related elements: implications for distinct genetic pathways of urinary bladder carcinogenesis. Urol Oncol 1998; 4: 58-72
18. Joyce D, Albanese C, Steer J, Fu MF, Bouzahzah B, Pestell RG. NF-κB and cell cycle regulation: the cyclin connection. Cytokine Growth Factor Rev 2001; 12: 73-90
19. Grana X, Reddy P. Cell cycle control in mammalian cells, role of cyclins, cyclin-dependent kinases and growth suppressor genes, and cyclin-dependent kinase inhibitors. Oncogene 1995; 11: 211-9
20. Sherr CJ, Roberts JM. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 1995; 9: 1149-63
21. Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AS. NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol 1999; 19: 5785-99
22. Ahmad N, Gupta S, Mukhtar H. Green tea polyphenol epigallocatechin-3- gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells. Arch Biochem Biophys 2000; 376: 338-46
23. Pennisi E. Superoxide relay ras protein's oncogenic message. Science 1997; 275: 1567-8
24. Liang YC, Lin-Shiau SY, Chen CF, Lin JK. Suppression of extracellular signals and cell proliferation through EGF receptor binding by (-)-epigallocatechin-3-gallate in human A431 epidermoid carcinoma cells. J Cell Biochem 1997; 67: 55-65