Calebin-A induces apoptosis and modulates MAPK family activity in drug resistant human gastric cancer cells

European Journal of Pharmacology

Volumn 591, Issue 1-3, 2008, Pages 252-258

  Li, Yan ^a   Li, Shaoqing ^a   Han, Yueheng ^a   Liu, Junye ^a   Zhang, Jian ^a   Li, Fuyang ^a   Wang, Yun ^b   Liu, Xinping ^a   Yao, Libo ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b Xi'an Greenpharma Natural Medicine Lab   (China)

Author keywords

Apoptosis; Calebin A; Curcuma longa; MAPK; MDR; P glycoprotein

Indexed keywords

CALEBIN A; CISPLATIN; CURCUMA LONGA EXTRACT; DOXORUBICIN; GLYCOPROTEIN P; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VINCRISTINE;

APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CANCER;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CINNAMATES; CURCUMA; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG THERAPY, COMBINATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; MONOTERPENES; P-GLYCOPROTEIN; STOMACH NEOPLASMS; VINCRISTINE;

EID: 48749106729     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.06.065     Document Type: Article

References (37)

1. Anuchapreeda S., Leechanachai P., Smith M.M., Ambudkar S.V., and Limtrakul P.N. Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells. Biochem. Pharmacol. 64 (2002) 573-582
2. Araujo C.C., and Leon L.L. Biological activities of Curcuma longa L. Mem. Inst. Oswaldo Cruz 96 (2001) 723-728
3. Barancik M., Bohacova V., Kvackajova J., Hudecova S., Krizanova O., and Breier A. SB203580, a specific inhibitor of p38-MAPK pathway, is a new reversal agent of P-glycoprotein-mediated multidrug resistance. Eur. J. Pharm. Sci. 14 (2001) 29-36
4. Bielak-Mijewska A., Piwocka K., Magalska A., and Sikora E. P-glycoprotein expression does not change the apoptotic pathway induced by curcumin in HL-60 cells. Cancer Chemother. Pharmacol. 53 (2004) 179-185
5. Cano-Gauci D.F., and Riordan J.R. Action of calcium antagonists on multidrug resistant cells. Specific cytotoxicity independent of increased cancer drug accumulation. Biochem. Pharmacol. 36 (1987) 2115-2123
6. Chaudhary P.M., and Roninson I.B. Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 66 (1991) 85-94
7. Chearwae W., Anuchapreeda S., Nandigama K., Ambudkar S.V., and Limtrakul P. Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder. Biochem. Pharmacol. 68 (2004) 2043-2052
8. Chen Y.R., and Tan T.H. Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin. Oncogene 17 (1998) 173-178
9. Chen H., Zhang Z.S., Zhang Y.L., and Zhou D.Y. Curcumin inhibits cell proliferation by interfering with the cell cycle and inducing apoptosis in colon carcinoma cells. Anticancer Res. 19 (1999) 3675-3680
10. Choi J.H., Lim H.Y., Joo H.J., Kim H.S., Yi J.W., Kim H.C., Cho Y.K., Kim M.W., and Lee K.B. Expression of multidrug resistance-associated protein1, P-glycoprotein, and thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection. Br. J. Cancer 86 (2002) 1578-1585
11. Choi B.H., Kim C.G., Lim Y., Shin S.Y., and Lee Y.H. Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway. Cancer Lett. 259 (2008) 111-118
12. Ding S., Chamberlain M., McLaren A., Goh L., Duncan I., and Wolf C.R. Cross-talk between signalling pathways and the multidrug resistant protein MDR-1. Br. J. Cancer 85 (2001) 1175-1184
13. Duvoix A., Blasius R., Delhalle S., Schnekenburger M., Morceau F., Henry E., Dicato M., and Diederich M. Chemopreventive and therapeutic effects of curcumin. Cancer Lett. 223 (2005) 181-190
14. Emanuel S.L., Chamberlin H.A., and Cohen D. Antimitotic drugs cause increased tumorigenicity of multidrug resistant cells. Int. J. Oncol. 14 (1999) 487-494
15. Endicott J.A., and Ling V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu. Rev. Biochem. 58 (1989) 137-171
16. Ji B.S., He L., and Liu G.Q. Reversal of P-glycoprotein-mediated multidrug resistance by CJX1, an amlodipine derivative, in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells. Life Sci. 77 (2005) 2221-2232
17. Kowalski P., Stein U., Scheffer G.L., and Lage H. Modulation of the atypical multidrug-resistant phenotype by a hammerhead ribozyme directed against the ABC transporter BCRP/MXR/ABCG2. Cancer Gene Ther. 9 (2002) 579-586
18. Lee Y.J., Galoforo S.S., Berns C.M., Chen J.C., Davis B.H., Sim J.E., Corry P.M., and Spitz D.R. Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells. J. Biol. Chem. 273 (1998) 5294-5299
19. Li Y., Liu J., Liu X., Xing K., Wang Y., Li F., and Yao L. Resveratrol-induced cell inhibition of growth and apoptosis in MCF7 human breast cancer cells are associated with modulation of phosphorylated Akt and caspase-9. Appl. Biochem. Biotechnol. 135 (2006) 181-192
20. Limtrakul P., Khantamat O., and Pintha K. Inhibition of P-glycoprotein activity and reversal of cancer multidrug resistance by Momordica charantia extract. Cancer Chemother. Pharmacol. 54 (2004) 525-530
21. Ludwig A., Dietel M., and Lage H. Identification of differentially expressed genes in classical and atypical multidrug-resistant gastric carcinoma cells. Anticancer Res. 22 (2002) 3213-3221
22. Mandlekar S., Yu R., Tan T.H., and Kong A.N. Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells. Cancer Res. 60 (2000) 5995-6000
23. Mansilla S., Rojas M., Bataller M., Priebe W., and Portugal J. Circumvention of the multidrug-resistance protein (MRP-1) by an antitumor drug through specific inhibition of gene transcription in breast tumor cells. Biochem. Pharmacol. 73 (2007) 934-942
24. Osborn M.T., and Chambers T.C. Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J. Biol. Chem. 271 (1996) 30950-30955
25. Park S.Y., and Kim D.S. Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease. J. Nat. Prod. 65 (2002) 1227-1231
26. Qureshi S., Shah A.H., and Ageel A.M. Toxicity studies on Alpinia galanga and Curcuma longa. Planta Med. 58 (1992) 124-127
27. Ramachandran C., and You W. Differential sensitivity of human mammary epithelial and breast carcinoma cell lines to curcumin. Breast Cancer Res. Treat. 54 (1999) 269-278
28. Shi Y., Han Y., Wang X., Zhao Y., Ning X., Xiao B., and Fan D. MGr1-Ag is associated with multidrug-resistant phenotype of gastric cancer cells. Gastric Cancer 5 (2002) 154-159
29. Sikic B.I., Fisher G.A., Lum B.L., Halsey J., Beketic-Oreskovic L., and Chen G. Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein. Cancer Chemother. Pharmacol. 40 (1997) S13-S19 Suppl
30. Simoni D., Rizzi M., Rondanin R., Baruchello R., Marchetti P., Invidiata F.P., Labbozzetta M., Poma P., Carina V., Notarbartolo M., Alaimo A., and D'Alessandro N. Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells. Bioorg. Med. Chem. Lett. 18 (2008) 845-849
31. Singer S.J. Some early history of membrane molecular biology. Annu. Rev. Physiol. 66 (2004) 1-27
32. Tan B., Piwnica-Worms D., and Ratner L. Multidrug resistance transporters and modulation. Curr. Opin. Oncol. 12 (2000) 450-458
33. Tang X.Q., Bi H., Feng J.Q., and Cao J.G. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VINCRISTINE. Acta Pharmacol. Sin. 26 (2005) 1009-1016
34. Tew K.D. Glutathione-associated enzymes in anticancer drug resistance. Cancer Res. 54 (1994) 4313-4320
35. Wang Y., Blandino G., Oren M., and Givol D. Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs. Oncogene 17 (1998) 1923-1930
36. Wu Y., Hiwasa T., Isogai E., Sonoda T., Kita K., Chen Z., Sugaya S., Yamamori H., Tanzawa H., and Suzuki N. Activation of MAP kinases by 5-fluorouracil in a 5-fluorouracil-resistant variant human cell line derived from a KT breast cancer cell line. Int. J. Oncol. 13 (1998) 1241-1245
37. Zhang L., Yu J., Park B.H., Kinzler K.W., and Vogelstein B. Role of BAX in the apoptotic response to anticancer agents. Science 290 (2000) 989-992