A comparison of the pharmacological properties of recombinant human and rat α1β2γ2L GABAA receptors in Xenopus oocytes

Clinical and Experimental Pharmacology and Physiology

Volumn 35, Issue 9, 2008, Pages 1002-1011

  Rahman, Mozibur ^a   Borra, Vijaya B ^a   Isaksson, Monica ^a   Johansson, Inga Maj ^a   Ragagnin, Gianna ^a   Bäckström, Torbjörn ^a   Wang, Ming De ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

2L and 2S isoforms; GABA; Human and rat 1 2 2L receptors; Neurosteroids

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 3BETA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1BETA2GAMMA2L; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1BETA2GAMMA2S; 5ALPHA PREGNAN 3ALPHA,21 DIOL 20 ONE; 5ALPHA PREGNAN 3BETA,20 DIOL; 5ALPHA PREGNAN 3BETA,20BETA DIOL; 5ALPHA PREGNANE 3ALPHA,20ALPHA DIOL; 5BETA PREGNAN 3ALPHA,21 DIOL 20 ONE; 5BETA PREGNAN 3BETA,20 DIOL; 5BETA PREGNAN 3BETA,21 DIOL 20 ONE; 5BETA PREGNANE 3ALPHA,20BETA DIOL; ANDROSTANEDIOL; DELTA4 PREGNAN 3ALPHA OL 20 ONE; ELTANOLONE; PENTOBARBITAL; PREGNENOLONE SULFATE; RECOMBINANT RECEPTOR; UC 1010; UC 1011; UC 1015; UC 1019; UC 1020;

ALLOSTERISM; ANIMAL CELL; ARTICLE; COMPARATIVE STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; IC 50; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; RECEPTOR UPREGULATION; XENOPUS;

ALLOSTERIC REGULATION; ANIMALS; CATALYTIC DOMAIN; CLONING, MOLECULAR; ELECTROPHYSIOLOGY; FEMALE; HUMANS; OOCYTES; PREGNENOLONE; PROTEIN ISOFORMS; PROTEIN SUBUNITS; RATS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

EID: 48749102675     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2008.04946.x     Document Type: Article

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