Ethiopatogenia of functional hypothalamic amenorrhea Interactions of central nervous system and peripherical neuropeptides responses;Etiopatogenia de la amenorrea hipotalámica funcional Interacción de las respuestas hormonales del Sistema Nervioso Central y Neuropéptidos Periféricos

Revista Argentina de Endocrinologia y Metabolismo

Volumn 45, Issue 2, 2008, Pages 75-88

  Fiszlejder, L ^a  

^a Hospital Carlos G   (United States)

Author keywords

Amenorrhea; CRH GnRH; Etiopathogenia; Ghrelin; Homeostasis; Leptine

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; C REACTIVE PROTEIN; CORTICOTROPIN; ESTROGEN; GHRELIN; HORMONE; INSULIN; LEPTIN; MELATONIN; NEUROPEPTIDE; OPIATE; PROGESTERONE; PROLACTIN; SOMATOMEDIN C;

AMENORRHEA; APPETITE; ATTENUATION; BODY COMPOSITION; CALORIC INTAKE; CARDIOVASCULAR RISK; CENTRAL NERVOUS SYSTEM; DISEASE CLASSIFICATION; DOPAMINERGIC SYSTEM; ENERGY EXPENDITURE; ESTROGEN DEFICIENCY; GASTROINTESTINAL TRACT; GONAD DYSFUNCTION; HOMEOSTASIS; HORMONE RESPONSE; HUMAN; LIVER; MALNUTRITION; MENSTRUAL CYCLE; MENTAL STRESS; METABOLISM; OSTEOPENIA; PANCREAS; PATHOGENESIS; PATHOPHYSIOLOGY; PHYSICAL ACTIVITY; PHYSIOLOGICAL STRESS; PROTEIN INTERACTION; REVIEW; SATIETY; THYROID GLAND;

EID: 48749099186     PISSN: 03264610     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (67)

1. Hayes F. J., Weld C. K., Martin K. A.y col. Gonadotropin releasing hormone deficiency; differential diagnosis and treatment. The Endocrinologist 9:36-44.1999
2. Yen S. C. Female hypogonstropic hypogonadism. Hypothalamic amenorrhea syndome. Endocinol. and. Metabol. Clinics N. A 22: 29-58.1993
3. Filicori M., Santoro N., Merrian G. R., y col. Characterization of the physiological pattern of episodic gonadotropin secretion trhoughout the human menstrual cycle. J. Clin. Endocinol. Metab. 62:1136-1143. 1986.
4. Berga S. L., Mortola J. F., Girton L. y col. Neuroendocrine aberrations in gonadal function disorders En Yen S.S.S.C.,Jaffe R.B.. Reproductive Endocrinology. Philadelphia W. B. Saunders p 576 -630.1991.
5. Reame N. F., Sauder S. E., Case G. D. y col. Pulsatile gonadotropin secretion in women with hypothalamic amenorrhea: evidence that reduced frecuency of gonadotropin releasing hormone secretion is the mechanism of persitent anovulation. J. Clin. Endocrinol. 61:851 -858. 1985
6. Crowley W. F., Filicoti M., Spratt D. I. y col. The physiology of gonadotropin releasing hormone secretion in men and women. Rec. Prog. Hormon. Res. 41:473-531.1985
7. Longcope C, Pratt J. H., Schneider S. H., y col. Aromatization of androgens by muscle and adipose tissue in vivo. J. Clin. Endocrinol. Metab. 45:146-154.1978..
8. Yen S. S. C. The human menstrual cycle: Neuendocrine regulation. En Yen S. S. D., Jaffe R.B. (ed) Reproductive Endocrinology. Philadelphia W.B. Saunders p 273-308.1991.
9. Gambacciani M., Yen S. S. C., Rasmussen D. D. GnRH release from the mediumbasal hipothalamus in vitro inhibition by corticotropin releasing factor. Neuroendocrinology. 43:533-536.1986.
10. Petraglia F., Sutton S., Vale W. y col. Corticotropin-releasing- factor decreases plaasma lutrnizing hormone levels in female sing hormone levels in female rats by inhibiting gonadotropin releasing hormone release into hypophisial-portal circulation. Endocrinology 120:1083-1088. 1987.
11. Kaye W. H, Gwrtsman H. E., George D. T. y col. Elevated cerebrospinal fluid levels of inmunoreactive corticotropin-realising-hormone in anorexia nervosa; relation to state of nutrition,adrenal function and intensity of depression. J. Clin. Endocrinol. Metab. 64:203 -208. 1987.
12. Matsunne H., Hirato K., Yanahara T. y col. Aromatization by skeletal muscle. J. Clin. Endocrinol. Metab. 63:717-720.1986.
13. Longcope C., Kato T., Horton R., y col. Aromatization by splanic tissue in men. J. Clin. Endocrinol. Metab. 58:1089-1099. 1984.
14. Schweikert H. U., Milevich L, Wilson J. D., Aromatization of androstenedione by cultured human fibroblast J. Clin. Endocrinol. Metab 43:785-891 1976.
15. Schweikert H. U., Milevich L., Wilsun J. D., Aromatization of androstenedione by isolated human hairs J. Clin. Endocrinol. Metab. 40:413-420. 1974.
16. Frish R. E., Canick J. A., Tulschinsky D. Human fatty marrow aromatices androgen to estrogen J. Clin. Endocrinol. 51: 394-403. 1980.
17. Yen S.S.C. Chronic anovulation due to CNS-Hypothalamic-Pituitary dysfunction en Reproductive Endolrinology. Yen S. S. C. y Jaffe R.B. Saunders W. B. pp 631-688 .1991.
18. Miller D.S., Reid R., Cetel N. y col. Pulsatile administration of low dose gonadotropin-releasing hormone (GnRH) for the induction of ovulation and pregnancy in patients with hypotalamic amenorrhea JAMA 250:2937, 1983.
19. Eastour B., Pugeat M., Lang F., Dechaud H., y col. Sex hormone binding globulin in womem with anorexia nervosa. Clin. Endocrinol. (Oxf) 24 :571-576, 1986.
20. Sirinathsinghji D. J., Mills I.H. Concentration patterns of plasma dehydroeandrosterona A5androstenediol and their sulphate testosterone and cortisol in normal healthi women and in women with anorexia nervosa. Acta Endocrinol. (Copenh). 108:255-260 1985.
21. Devesa J., Perez Fernandez, Bokser L. y col. Adrenal androgen swcretion and dopaminergic activity in anorexia nervosa. Hormon Metab. Res. 20 : 57-60 .1988.
22. Winterer L., Gwirsman H. E., George D. T. y col. Adrenocorticotropin stimulated adrenal androgen secretion in anorexia nervosa impareid secretion at low weith with normalization after long term weight recovery. J. Clin. Endocrinol. Metab. 61:693-697. 1985.
23. Genazzani A. D., Bersi C., Luisi S., y col. Increased adrenal steroid secretion in response to CRF in women with hypothalamic amenorrhea .J. Steroid Biochem Mol. Biol. 78: 247-252 2001
24. Rickenlund A. Carstrom K.,Elcblom B. Y col. Hyperandrogenicity is an alternative mechanism underlying oligomenorrhea or amenorrhea in female athletes and my improve physical perfomamce. Fertil. Steril. 79:947-955.2003.
25. Rickenlund A,Thoren M.,Calstrom K., y col. Diurnal profiles testosterona and pitutary hormones suggest different mechanism for menstrual disturbances in endurance athletes. J. Endocrinol. Endocrinol. Metab. 89:702-704.2004.
26. Zummoff B., Walsh B.T., Katz J. L. y col. Sub normal plasma dehydroisoanddrosterone to cortisol ratio in anorexia nervosa, second hormone parameter of ontogenic regresion J Clin Endocrinol Metab 56:.668-672. 1983.
27. Coleman D. L., Schwizer R. W., Leiter E.H., Effect of genetic background on the therapeutic effects of dehidroepiandrosterone (DHEA) in diabetes obesity mutans and age normal mice. Diabetes. 33:26-34.1984.
28. Lucas J. A., Hammed S. A., Casey L. M. y col. Prevention autoantibody formation and prolonged survival in New Zeland black /New Zeland withe F1 mice fed' by dehydroepiandrosterone. J. Clin. Invest 55:2091-2099. 1985.
29. Barret Conner F., Khaw K.T., Yen S.S.C. A prospective study of dehydrodepiandrosterone sulfate mortality and cardiovascular disease. J. Engl J. Med. 315:1519-1530. 1986.
30. Bulbrook R.D., Hayward J. L. Spicer C. C. Relation betwin urinary androgen and corticoid secretion ,excretion and subsequent breast cancer Lancet 2 :395-403. 1975
31. Thoman M. L.,Weilgle W. O. The cellular and subcellular immnosenscece. Adv. Immunol. 46:221-232. 1989.
32. Soykara L.A., Misra M., Frenchman A. y col. Abnormal bone mineral accruall in adolescent girls with anorexia nervosa. J. Clin. Endocrinol. Metab. 87 : 4177-4185. 2002
33. Miller K. K., Lawson E. A., Marthur V. y col. Androgens in woman with anorexia nervosa and normal -with woman wirh hypothalamic amenorrhea. J. Clin. Endocrinol Metab. 92 :1334-1339.2007.
34. Chan J. L, Hest K., De Paroli A. M., Veldhuis J. L. y col. The rol of falling leptin levels in the neuroendocrine and metabolic adptation to short term starvation in healty men. J. Clin. Invesr. 111 : 1409-1421.2003.
35. Miller K K. Parulekar M.S., Schonfeld E. y col. J.Cin. Endocrinol. Metab. Dreased leptin levels in normal weight vomen with hypothalamic amenorrhea:the effects of body composition and nutritional intake. J. Clin. Endocrinol. Metab. 83:2909-2312 1998.
36. Meller K. K., Grispoon S., Gleysteen S. y col. Preservation of neuroendocrine control of reproductive function despite severe undernutrition. J. Clin. Endocrinol. Metab. 89 :4434-4438, 2004.
37. Rigotti N. N. A., Neer R. M., States S. J. y col. The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass. JAMA 265 :1133-1138.1991.
38. Pittas A. G., Joseph N. A, and Greenberg A. S. Adipocytokines and insulin resistance. J.Clin.Metab. 89 : 447-452. 2004
39. Zigman J.M. and Elmquist Minireview From anorexia to obesity -the yin and yang 9f body weight control. Endocrinology. 144 : 3749-3756. 2003.
40. Weigle D. S., Cummigs D. E., Neswby P. D., y col. Roles of lepin and ghrelin in the loss of body weight caused by a low fat, high carboydrate diet. J. Clin Endocrinol. Metab. 88:1577-1586. 2003.
41. Pittas A.G. Ghrelin: more than a natural GH secretagogue and / or an orexigenic factor. Clin. Endocrinol: 62:1-17. 2005 .
42. Biller B. M. K. , Federoff H. J., Koening J. L. y col. Abnormal cortisol secretion and response to cortocotropin -releasing - hormone in women with hypotalamic amenorrhea J. Clin. Endocrinol.. Metab.70:331-317.1990 .
43. Suh B., Liu J., Berga S. y col. Hypercortisolism in patients with functional hypothalamic amenorrhea. J. Clin.Endocrinol. Metab. 66: 733-738. 1988 .
44. Miller K. K., Klibanski A. Amenorrireic bone loss. J.Clin.Endocrinol Metab. 84:1775-1783. 1999
45. Ding J. K., Sheckter C. B., Drink water B. I. y col . High serum cortisol levels in exercise associated amenorrhea. Ann. Intern. Med. 108:530-534. 1988
46. Loucks A. B, Mortola J. F., Girton L. y col. Alterations in the hypothamic pituitary ovarian and the hypothalamic pituitary axes in the athetic women. J. Clin. Endocrinol. Metab. 68:402-411. 1989.
47. Warren M. P. and Ftied J.L. Hypothalamic Amenorrhea. The effectes of environmental stress on the reproductive system. A central effect of the central nervous system. Endocrinol Metab. Clin N. A. 30:611-629 .2001 .
48. Suh B., Liu J., Berga S. y col. Hypercortisolism in patients with functional hypothalamic amenorrhea J.Clin .Endocrinol. Metab. 66:733-739. 1988 .
49. Warren M. P., Vousonghan F., Geer E. B. y col. Fnctional hypotalamic amenorrhea :hypoleptinemia and disordened eating. J.Clin. Endocrinol .Metab. 84. 873-877. 1999 .
50. Ostberg J. E., Storryt C., Donaldt A. E. y col. A dose-response study hormone replacement in young hypogonadal women: effects on intima media thckness and metabolism. Clin. Endocrinology .66 : 557-564 .2007 .
51. Lawson E. A., Miller K. K., Mathur V. A. y col. Hormonal and nutritional effects on cardiovascular risk markers in young women .J.Clin. Endocrinol.Metab. 92:3089-3094 .2007.
52. Weinbrenner T., Zuger M., Jacobi G, y col. Lipoprotein metabolism in patients with anorexia nervosa :case control study investigating the mechanisms leading to hypercholesterolemia Br J.Nur.91:959-969.2004.
53. Ohwada R., Hotta M., Takano. Etiology of hypercholesterolemia in patients with anorexia nervosa. Int. J. Eat.Disord. 39:598-601. 2006.
54. Ridker P.M. ,Rifai N.,Rose L. y col. Comparison of C reactive protein and low density lipoproteins cholesterol levels in the prediction of ferst cardiovascular events N. Engl. J. Med. 347:1557-1565. 2002.
55. Signorini A., De Filippo E., Panico S., De Caprio C. y col. Long-term mortality in anorexia nervosa: a reprt after an 8 year follow-up and a review of the most recent literature. Eur.J. Clin Nutr. 61 :119-122. 2007.
56. Ridker P. M., Hennkens C. K., Buring J. E. y col. C-reative protein and others markers of inflamation in in the prediction of cardiovascular disease in women. N. Engl. J. Med. 342:836-843. 2000.
57. Albert C. M., Ma J., Rifai N, y col. Propestive study of C-reactive protein, homocycisteine and plasma lipid levels as predictors of sudden cardiac death. Circulation. 105:2598-2599. 2002.
58. Herzog D. B., Grenwood D. N., Dover D. J. y col. Mortality in eating disorders : descriptive study. Int.J.Eat.Disord. 28:20-26. 2000.
59. Raitakari M., Mansikkanieni K., Marnemi J. y col. Distribution and determinants of serum high- sensivity C-reactive protein in a population of young adults : the Cardiovascular Risk in young Eins Study. J. Intern. Med. 258 : 428-434. 2005.
60. Bailargeon J. P., Mc Clish D. K., Essah P. A. y col. Association between the current use of low- dose oral contraceptives and cardiovascular arterial disease: a meta-anallysis. J. Endocrinol. Metab. 90 : 3863-3870. 2005.
61. Writing Group for the Women's Health Initiative Investigators Risk and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Healt Initiative randomized controlled trial JAMA 288 : 321-333. 2002.
62. Rosi R., Burst F., Veronesi B. y col. Effects of progestins on estrogen-induces increase in C-reactive protein in postmenopausel women. Maturitas. 49 :315-320. 2004 .
63. Reuben D. B., Palla S. L., Hu P. y col. Progestings affect mechanism of estrogen- induced C-reactive ptotein stimulation. Am. J. Med.: 119-167 167. 2006.
64. Vitale C., Cormodi A., Gebara O. y col. Intreleukin-6 and folow-metiated dilatation as markers of increased vascular inflamation im women receiving hormone therapy. Menopause. 12:552-558. 2005 .
65. Sesnilo G., Miller K. K., Haydem D. y col. Inflatory cardiovascujar risk markers in women with hypopituitarism. J. Clin. Endocrinol. Metab. 86:5574-5781. 2002.
66. Vongpatanasin W., Tuncel M., Wang Z. y col. Differential effects of oral versus transdermal estrogen replacement therapy on C-reactive protein in postmenopausal women. J.Am Coll. Cardiol. 41: 1358-1363. 2002.
67. Ohwada R., Hotta M., OIKAWA S. y col. Etiology of hypercholesterolemia in patients with anorexia nervosa. Int J. Eat Disord. 39 : 598-601. 2006.