Caspase cleavage of phospholipase D1 in vitro alters its regulation and reveals a novel property of the "loop" region

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1781, Issue 8, 2008, Pages 376-382

  Riebeling, Christian ^a   Bourgoin, Sylvain ^b   Shields, Dennis ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Apoptosis; Caspase; Phosphatidic acid; Phospholipase D; Regulatory domain

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 8; GUANOSINE TRIPHOSPHATASE; PHOSPHOLIPASE D1; PHOSPHOLIPASE D2; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HELA CELLS; HUMANS; MICE; PHOSPHOLIPASE D; PROTEIN STRUCTURE, SECONDARY; TETRADECANOYLPHORBOL ACETATE;

EID: 48649107037     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2008.05.007     Document Type: Article

References (49)

1. Exton J.H. Phospholipase D: enzymology, mechanisms of regulation, and function. Physiol. Rev. 77 (1997) 303-320
2. Becker K.P., and Hannun Y.A. Protein kinase C and phospholipase D: intimate interactions in intracellular signaling. Cell. Mol. Life Sci. 62 (2005) 1448-1461
3. Jenkins G.H., Fisette P.L., and Anderson R.A. Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J. Biol. Chem. 269 (1994) 11547-11554
4. Fang Y., Park I.H., Wu A.L., Du G., Huang P., Frohman M.A., Walker S.J., Brown H.A., and Chen J. PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1. Curr. Biol. 13 (2003) 2037-2044
5. Kim J.H., Kim H.W., Jeon H., Suh P.G., and Ryu S.H. Phospholipase D1 regulates cell migration in a lipase activity-independent manner. J. Biol. Chem. 281 (2006) 15747-15756
6. Jones D., Morgan C., and Cockcroft S. Phospholipase D and membrane traffic. Potential roles in regulated exocytosis, membrane delivery and vesicle budding. Biochim. Biophys. Acta 1439 (1999) 229-244
7. Siddhanta A., and Shields D. Secretory vesicle budding from the trans-Golgi network is mediated by phosphatidic acid levels. J. Biol. Chem. 273 (1998) 17995-17998
8. Lee C.S., Kim I.S., Park J.B., Lee M.N., Lee H.Y., Suh P.G., and Ryu S.H. The phox homology domain of phospholipase D activates dynamin GTPase activity and accelerates EGFR endocytosis. Nat. Cell Biol. 8 (2006) 477-484
9. Zeniou-Meyer M., Zabari N., Ashery U., Chasserot-Golaz S., Haeberle A.M., Demais V., Bailly Y., Gottfried I., Nakanishi H., Neiman A.M., Du G., Frohman M.A., Bader M.F., and Vitale N. Phospholipase D1 production of phosphatidic acid at the plasma membrane promotes exocytosis of large dense-core granules at a late stage. J. Biol. Chem. 282 (2007) 21746-21757
10. Foster D.A. Regulation of mTOR by phosphatidic acid?. Cancer Res. 67 (2007) 1-4
11. Nozawa Y. Roles of phospholipase D in apoptosis and pro-survival. Biochim. Biophys. Acta 1585 (2002) 77-86
12. Hammond S.M., Altshuller Y.M., Sung T.C., Rudge S.A., Rose K., Engebrecht J., Morris A.J., and Frohman M.A. Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family. J. Biol. Chem. 270 (1995) 29640-29643
13. Colley W.C., Sung T.C., Roll R., Jenco J., Hammond S.M., Altshuller Y., Bar-Sagi D., Morris A.J., and Frohman M.A. Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization. Curr. Biol. 7 (1997) 191-201
14. Okamura S., and Yamashita S. Purification and characterization of phosphatidylcholine phospholipase D from pig lung. J. Biol. Chem. 269 (1994) 31207-31213
15. Hammond S.M., Jenco J.M., Nakashima S., Cadwallader K., Gu Q., Cook S., Nozawa Y., Prestwich G.D., Frohman M.A., and Morris A.J. Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha. J. Biol. Chem. 272 (1997) 3860-3868
16. Ganley I.G., Walker S.J., Manifava M., Li D., Brown H.A., and Ktistakis N.T. Interaction of phospholipase D1 with a casein-kinase-2-like serine kinase. Biochem. J. 354 (2001) 369-378
17. Jenco J.M., Rawlingson A., Daniels B., and Morris A.J. Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins. Biochemistry 37 (1998) 4901-4909
18. Liscovitch M., Chalifa V., Pertile P., Chen C.S., and Cantley L.C. Novel function of phosphatidylinositol 4,5-bisphosphate as a cofactor for brain membrane phospholipase D. J. Biol. Chem. 269 (1994) 21403-21406
19. Freyberg Z., Sweeney D., Siddhanta A., Bourgoin S., Frohman M., and Shields D. Intracellular localization of phospholipase D1 in mammalian cells. Mol. Biol. Cell. 12 (2001) 943-955
20. Freyberg Z., Bourgoin S., and Shields D. Phospholipase D2 is localized to the rims of the Golgi apparatus in Mammalian cells. Mol. Biol. Cell 13 (2002) 3930-3942
21. Freyberg Z., Siddhanta A., and Shields D. "Slip, sliding away": phospholipase D and the Golgi apparatus. Trends Cell Biol. 13 (2003) 540-546
22. Du G., Huang P., Liang B.T., and Frohman M.A. Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis. Mol. Biol. Cell. 15 (2004) 1024-1030
23. Lehman N., Ledford B., Di Fulvio M., Frondorf K., McPhail L.C., and Gomez-Cambronero J. Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR. FASEB J. (2007)
24. Chen Y., Zheng Y., and Foster D.A. Phospholipase D confers rapamycin resistance in human breast cancer cells. Oncogene 22 (2003) 3937-3942
25. Riebeling C., Müller C., and Geilen C.C. Expression and regulation of phospholipase D isoenzymes in human melanoma cells and primary melanocytes. Melanoma Res. 13 (2003) 555-562
26. Kasai T., Ohguchi K., Nakashima S., Ito Y., Naganawa T., Kondo N., and Nozawa Y. Increased activity of oleate-dependent type phospholipase D during actinomycin D-induced apoptosis in Jurkat T cells. J. Immunol. 161 (1998) 6469-6474
27. Kang J.H., Shin I., and Han J.S. Changes of phospholipase D activity in TNF-alpha and anti-Fas/Apo1 monoclonal antibody induced apoptosis in HL-60 and A20 cells. Exp. Mol. Med. 30 (1998) 21-27
28. Chen J.S., Chai M.Q., Chen H.H., Zhao S., and Song J.G. Regulation of phospholipase D activity and ceramide production in daunorubicin-induced apoptosis in A-431 cells. Biochim. Biophys. Acta 1488 (2000) 219-232
29. Lee S.Y., Oh J.Y., Lee M.J., Jang M.J., Park H.Y., Kim J.W., Min do S., Park Y.M., Chang Y.C., Bae Y.S., and Kwak J.Y. Anti-apoptotic mechanism and reduced expression of phospholipase D in spontaneous and Fas-stimulated apoptosis of human neutrophils. Eur. J. Immunol. 34 (2004) 2760-2770
30. Xie Z., Ho W.T., and Exton J.H. Association of N- and C-terminal domains of phospholipase D is required for catalytic activity. J. Biol. Chem. 273 (1998) 34679-34682
31. Garcia-Calvo M., Peterson E.P., Rasper D.M., Vaillancourt J.P., Zamboni R., Nicholson D.W., and Thornberry N.A. Purification and catalytic properties of human caspase family members. Cell Death Differ. 6 (1999) 362-369
32. Marcil J., Harbour D., Naccache P.H., and Bourgoin S. Human phospholipase D1 can be tyrosine-phosphorylated in HL-60 granulocytes. J. Biol. Chem. 272 (1997) 20660-20664
33. Liu X., Kim C.N., Yang J., Jemmerson R., and Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86 (1996) 147-157
34. Bligh E.G., and Dyer W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37 (1959) 911-917
35. Nakashima T., Sekiguchi T., Kuraoka A., Fukushima K., Shibata Y., Komiyama S., and Nishimoto T. Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells. Molecular and cellular biology 13 (1993) 6367-6374
36. Yamazaki M., Zhang Y., Watanabe H., Yokozeki T., Ohno S., Kaibuchi K., Shibata H., Mukai H., Ono Y., Frohman M.A., and Kanaho Y. Interaction of the small G protein RhoA with the C terminus of human phospholipase D1. J. Biol. Chem. 274 (1999) 6035-6038
37. Sung T.C., Zhang Y., Morris A.J., and Frohman M.A. Structural analysis of human phospholipase D1. J. Biol. Chem. 274 (1999) 3659-3666
38. Mancini M., Machamer C.E., Roy S., Nicholson D.W., Thornberry N.A., Casciola-Rosen L.A., and Rosen A. Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis. J. Cell Biol. 149 (2000) 603-612
39. Brown H.A., Gutowski S., Moomaw C.R., Slaughter C., and Sternweis P.C. ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity. Cell 75 (1993) 1137-1144
40. Liscovitch M. Phosphatidylethanol biosynthesis in ethanol-exposed NG108-15 neuroblastoma X glioma hybrid cells. Evidence for activation of a phospholipase D phosphatidyl transferase activity by protein kinase C. J. Biol. Chem. 264 (1989) 1450-1456
41. Thornberry N.A., Rano T.A., Peterson E.P., Rasper D.M., Timkey T., Garcia-Calvo M., Houtzager V.M., Nordstrom P.A., Roy S., Vaillancourt J.P., Chapman K.T., and Nicholson D.W. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272 (1997) 17907-17911
42. Stennicke H.R., Renatus M., Meldal M., and Salvesen G.S. Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8. Biochem. J. 350 (2000) 563-568
43. Ha S.H., Kim D.H., Kim I.S., Kim J.H., Lee M.N., Lee H.J., Kim J.H., Jang S.K., Suh P.G., and Ryu S.H. PLD2 forms a functional complex with mTOR/raptor to transduce mitogenic signals. Cell Signal 18 (2006) 2283-2291
44. Kook S., and Exton J.H. Identification of interaction sites of protein kinase Calpha on phospholipase D1. Cell. Signal 17 (2005) 1423-1432
45. Zhong M., Shen Y., Zheng Y., Joseph T., Jackson D., and Foster D.A. Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells. Biochem. Biophys. Res. Commun. 302 (2003) 615-619
46. Chen Y., Rodrik V., and Foster D.A. Alternative phospholipase D/mTOR survival signal in human breast cancer cells. Oncogene 24 (2005) 672-679
47. Mejillano M., Yamamoto M., Rozelle A.L., Sun H.Q., Wang X., and Yin H.L. Regulation of apoptosis by phosphatidylinositol 4,5-bisphosphate inhibition of caspases, and caspase inactivation of phosphatidylinositol phosphate 5-kinases. J. Biol. Chem. 276 (2001) 1865-1872
48. Sanjay A., Fu J., and Kreibich G. DAD1 is required for the function and the structural integrity of the oligosaccharyltransferase complex. J. Biol. Chem. 273 (1998) 26094-26099
49. Cai S., and Exton J.H. Determination of interaction sites of phospholipase D1 for RhoA. Biochem. J. 355 (2001) 779-785