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Volumn 9, Issue 7, 2008, Pages 1214-1240

Key labeling technologies to tackle sizeable problems in RNA structural biology

Author keywords

Dynamics; FRET; Isotopic labeling; Ligation; NMR; Raman; RNA dynamics and folding and structure; X ray crystallography

Indexed keywords

CARBON 13; DEUTERIUM; FLUORINE; NITROGEN 15; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RIBOZYME; RNA; RNA POLYMERASE;

EID: 48649103008     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms9071214     Document Type: Review
Times cited : (44)

References (117)
  • 1
    • 48649090442 scopus 로고    scopus 로고
    • Gesteland, R.F, Cech, T.R, Atkins. J.F, Eds, Cold Spring Harbor Laboratory Press: New York
    • Gesteland, R.F.; Cech, T.R.; Atkins. J.F. (Eds) RNA World; Cold Spring Harbor Laboratory Press: New York, 2006; pp 1-768.
    • (2006) RNA World , pp. 1-768
  • 2
    • 34548395468 scopus 로고    scopus 로고
    • The ribosome in focus: New structures bring new insights
    • Korostelev, A.; Noller, H.F. The ribosome in focus: new structures bring new insights. Trends Biochem. Sci. 2007, 32, 434-441.
    • (2007) Trends Biochem. Sci , vol.32 , pp. 434-441
    • Korostelev, A.1    Noller, H.F.2
  • 3
    • 39749138785 scopus 로고    scopus 로고
    • A structural understanding of the dynamic ribosome machine
    • Steitz, TA. A structural understanding of the dynamic ribosome machine. Nat. Rev. Mol. Cell. Biol. 2008, 9, 242-253.
    • (2008) Nat. Rev. Mol. Cell. Biol , vol.9 , pp. 242-253
    • Steitz, T.A.1
  • 4
    • 33745050151 scopus 로고    scopus 로고
    • Cryo-electron microscopy of spliceosomal components
    • Stark, H.; Lührmann, R. Cryo-electron microscopy of spliceosomal components. Annu. Rev. Biophys. Biomol. Struct. 2006, 35, 435-457.
    • (2006) Annu. Rev. Biophys. Biomol. Struct , vol.35 , pp. 435-457
    • Stark, H.1    Lührmann, R.2
  • 5
    • 42249093677 scopus 로고    scopus 로고
    • Isolation of an active step I spliceosome and composition of its RNP core
    • Bessonov, S.; Anokhina, M.; Will, C. L.; Urlaub, H.; Luhrmann, R Isolation of an active step I spliceosome and composition of its RNP core. Nature 2008, 452, 846-850.
    • (2008) Nature , vol.452 , pp. 846-850
    • Bessonov, S.1    Anokhina, M.2    Will, C.L.3    Urlaub, H.4    Luhrmann, R.5
  • 7
    • 34548454557 scopus 로고    scopus 로고
    • Wakeman, C.A.; Winkler, W.C.; Dann, C.E. 3rd. Structural features of metabolite-sensing riboswitches. Trends Biochem. Sci. 2007, 32, 415-424.
    • Wakeman, C.A.; Winkler, W.C.; Dann, C.E. 3rd. Structural features of metabolite-sensing riboswitches. Trends Biochem. Sci. 2007, 32, 415-424.
  • 8
    • 34347401399 scopus 로고    scopus 로고
    • R Riboswitches: Small-molecule recognition by gene regulatory RNAs
    • Edwards, T.E.; Klein, D.J.; Ferré-DAmaré, A.R Riboswitches: small-molecule recognition by gene regulatory RNAs. Curr. Opin. Struct. Biol. 2007, 17, 273-279.
    • (2007) Curr. Opin. Struct. Biol , vol.17 , pp. 273-279
    • Edwards, T.E.1    Klein, D.J.2    Ferré-DAmaré, A.3
  • 9
    • 33847698971 scopus 로고    scopus 로고
    • The relationship between non-protein-coding DNA and eukaryotic complexity
    • Taft, R.J.; Pheasant, M.; Mattick, J.S. The relationship between non-protein-coding DNA and eukaryotic complexity. Bioessays 2007, 29, 288-99.
    • (2007) Bioessays , vol.29 , pp. 288-299
    • Taft, R.J.1    Pheasant, M.2    Mattick, J.S.3
  • 12
    • 0000353016 scopus 로고    scopus 로고
    • The use of NMR methods for conformational studies of nucleic acids
    • Wijmenga, S. S.; van Buuren, B.N.M. The use of NMR methods for conformational studies of nucleic acids. Prog. NMR Spectrosc. 1998, 32, 287-387.
    • (1998) Prog. NMR Spectrosc , vol.32 , pp. 287-387
    • Wijmenga, S.S.1    van Buuren, B.N.M.2
  • 13
    • 10744232623 scopus 로고    scopus 로고
    • New NMR experiments for RNA nucleobase resonance assignment and chemical shift analysis of an RNA UUCG tetraloop
    • Furtig, B.; Richter, C.; Bermel, W.; Schwalbe, H. New NMR experiments for RNA nucleobase resonance assignment and chemical shift analysis of an RNA UUCG tetraloop. J. Biomol. NMR 2004, 28, 69-79.
    • (2004) J. Biomol. NMR , vol.28 , pp. 69-79
    • Furtig, B.1    Richter, C.2    Bermel, W.3    Schwalbe, H.4
  • 14
    • 24744459633 scopus 로고    scopus 로고
    • NMR methods for studying the structure and dynamics of RNA
    • Latham, M. P.; Brown, D. J.; McCallum, S. A.; Pardi, A. NMR methods for studying the structure and dynamics of RNA. Chembiochem. 2005, 6, 1492-1505.
    • (2005) Chembiochem , vol.6 , pp. 1492-1505
    • Latham, M.P.1    Brown, D.J.2    McCallum, S.A.3    Pardi, A.4
  • 17
    • 33847302075 scopus 로고    scopus 로고
    • Preparation and crystallization of RNA
    • Golden, B. L. Preparation and crystallization of RNA. Methods Mol. Biol. 2007, 363, 239-257.
    • (2007) Methods Mol. Biol , vol.363 , pp. 239-257
    • Golden, B.L.1
  • 18
    • 0034101184 scopus 로고    scopus 로고
    • Solving large RNA structures by X-ray crystallography
    • Cate, J. H.; Doudna, J. A. Solving large RNA structures by X-ray crystallography. Methods Enzymol. 2000, 317, 169-180.
    • (2000) Methods Enzymol , vol.317 , pp. 169-180
    • Cate, J.H.1    Doudna, J.A.2
  • 19
    • 4344596976 scopus 로고    scopus 로고
    • Crystallization of RNA and RNA-protein complexes
    • Ke, A.; Doudna, J. A. Crystallization of RNA and RNA-protein complexes. Methods 2004, 34, 408-414.
    • (2004) Methods , vol.34 , pp. 408-414
    • Ke, A.1    Doudna, J.A.2
  • 20
    • 0034840624 scopus 로고    scopus 로고
    • RNA oligonucleotide synthesis via 5′-silyl-2′- orthoester chemistry
    • Scaringe, SA. RNA oligonucleotide synthesis via 5′-silyl-2′- orthoester chemistry. Methods 2001, 23, 206-217.
    • (2001) Methods , vol.23 , pp. 206-217
    • Scaringe, S.A.1
  • 21
    • 0023623129 scopus 로고
    • In vitro RNA synthesis with SP6 RNA polymerase
    • Krieg, PA.; Melton, DA. In vitro RNA synthesis with SP6 RNA polymerase. Methods Enzymol. 1987, 155, 397-415.
    • (1987) Methods Enzymol , vol.155 , pp. 397-415
    • Krieg, P.A.1    Melton, D.A.2
  • 22
    • 0024819449 scopus 로고
    • Synthesis of small RNAs using T7 RNA polymerase
    • Milligan, J.F.; Uhlenbeck, O.C. Synthesis of small RNAs using T7 RNA polymerase. Methods Enzymol. 1989, 180, 51-62.
    • (1989) Methods Enzymol , vol.180 , pp. 51-62
    • Milligan, J.F.1    Uhlenbeck, O.C.2
  • 23
    • 0027991544 scopus 로고
    • In vitro transcription: Preparative RNA yields in analytical scale reactions
    • Pokrovskaya, I.D.; Gurevich, V.V. In vitro transcription: preparative RNA yields in analytical scale reactions. Anal. Biochem. 1994, 220, 420-423.
    • (1994) Anal. Biochem , vol.220 , pp. 420-423
    • Pokrovskaya, I.D.1    Gurevich, V.V.2
  • 25
    • 0031686310 scopus 로고    scopus 로고
    • T7 RNA polymerase produces 5′ end heterogeneity during in vitro transcription from certain templates
    • Pleiss, J.A.; Derrick, M.L.; Uhlenbeck, O.C. T7 RNA polymerase produces 5′ end heterogeneity during in vitro transcription from certain templates. RNA 1998, 4, 1313-1317.
    • (1998) RNA , vol.4 , pp. 1313-1317
    • Pleiss, J.A.1    Derrick, M.L.2    Uhlenbeck, O.C.3
  • 26
    • 0032916514 scopus 로고    scopus 로고
    • More mistakes by T7 RNA polymerase at the 5′ ends of in vitro-transcribed RNAs
    • Helm, M.; Brulé, H.; Giegé, R.; Florentz, C. More mistakes by T7 RNA polymerase at the 5′ ends of in vitro-transcribed RNAs. RNA 1999, 5, 618-621.
    • (1999) RNA , vol.5 , pp. 618-621
    • Helm, M.1    Brulé, H.2    Giegé, R.3    Florentz, C.4
  • 27
    • 0024269992 scopus 로고
    • RNA synthesis: Strategies for the use of bacteriophage RNA polymerases
    • Krupp, G. RNA synthesis: strategies for the use of bacteriophage RNA polymerases. Gene 1988, 72, 75-89.
    • (1988) Gene , vol.72 , pp. 75-89
    • Krupp, G.1
  • 28
    • 0025748046 scopus 로고
    • Synthesis and purification of large amounts of RNA oligonucleotides
    • Wyatt, J. R.; Chastain, M.; Puglisi, J. D. Synthesis and purification of large amounts of RNA oligonucleotides. Biotechniques 1991, 11, 764-769.
    • (1991) Biotechniques , vol.11 , pp. 764-769
    • Wyatt, J.R.1    Chastain, M.2    Puglisi, J.D.3
  • 29
    • 0028820398 scopus 로고
    • Biochemical and NMR studies of RNA conformation with an emphasis on RNA pseudoknots
    • Puglisi, J.D.; Wyatt, J.R. Biochemical and NMR studies of RNA conformation with an emphasis on RNA pseudoknots. Methods Enzymol. 1995, 261, 323-350.
    • (1995) Methods Enzymol , vol.261 , pp. 323-350
    • Puglisi, J.D.1    Wyatt, J.R.2
  • 30
    • 0025817050 scopus 로고
    • A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3′ end blocked for transesterification
    • Grosshans, C.A.; Cech, T.R. A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3′ end blocked for transesterification. Nucleic Acids Res. 1991, 19, 3875-3880.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3875-3880
    • Grosshans, C.A.1    Cech, T.R.2
  • 31
    • 0029919746 scopus 로고    scopus 로고
    • Use of cis- and trans-ribozymes to remove 5′ and 3′ heterogeneities from milligrams of in vitro transcribed RNA
    • Ferré-D'Amaré, A.R.; Doudna, JA. Use of cis- and trans-ribozymes to remove 5′ and 3′ heterogeneities from milligrams of in vitro transcribed RNA. Nucleic Acids Res. 1996, 24, 977-978.
    • (1996) Nucleic Acids Res , vol.24 , pp. 977-978
    • Ferré-D'Amaré, A.R.1    Doudna, J.A.2
  • 32
    • 0030012860 scopus 로고    scopus 로고
    • th; Kool, E.T. Non-hydrogen bonding 'terminator' nucleosides increase the 3′-end homogeneity of enzymatic RNA and DNA synthesis. Nucleic Acids Res. 1996, 24, 2044-2052.
    • th; Kool, E.T. Non-hydrogen bonding 'terminator' nucleosides increase the 3′-end homogeneity of enzymatic RNA and DNA synthesis. Nucleic Acids Res. 1996, 24, 2044-2052.
  • 33
    • 0032827799 scopus 로고    scopus 로고
    • A simple and efficient method to reduce nontemplated nucleotide addition at the 3 terminus of RNAs transcribed by T7 RNA polymerase
    • Kao, C.; Zheng, M.; Rüdisser, S. A simple and efficient method to reduce nontemplated nucleotide addition at the 3 terminus of RNAs transcribed by T7 RNA polymerase. RNA 1999, 5, 1268-1272.
    • (1999) RNA , vol.5 , pp. 1268-1272
    • Kao, C.1    Zheng, M.2    Rüdisser, S.3
  • 34
    • 1342269713 scopus 로고    scopus 로고
    • Superior 5′ homogeneity of RNA from ATP-initiated transcription under the T7 phi 2.5 promoter
    • Coleman, T.M.; Wang, G.; Huang, F. Superior 5′ homogeneity of RNA from ATP-initiated transcription under the T7 phi 2.5 promoter. Nucleic Acids Res. 2004, 32, el4.
    • (2004) Nucleic Acids Res , vol.32
    • Coleman, T.M.1    Wang, G.2    Huang, F.3
  • 35
    • 23344446294 scopus 로고    scopus 로고
    • Resolution enhanced homonuclear carbon decoupled triple resonance experiments for unambiguous RNA structural characterization
    • Dayie, K.T. Resolution enhanced homonuclear carbon decoupled triple resonance experiments for unambiguous RNA structural characterization. J. Biomol. NMR 2005, 32, 129-139.
    • (2005) J. Biomol. NMR , vol.32 , pp. 129-139
    • Dayie, K.T.1
  • 36
    • 34547659860 scopus 로고    scopus 로고
    • Recombinant RNA technology: The tRNA scaffold
    • Ponchon, L.; Dardel, F. Recombinant RNA technology: the tRNA scaffold. Nat. Methods 2007, 4, 571-576.
    • (2007) Nat. Methods , vol.4 , pp. 571-576
    • Ponchon, L.1    Dardel, F.2
  • 38
    • 0029805728 scopus 로고    scopus 로고
    • HPLC purification of RNA for crystallography and NMR
    • Anderson, A. C.; Scaringe, S. A.; Earp, B. E.; Frederick, C. A. HPLC purification of RNA for crystallography and NMR. RNA 1996, 2, 110-117.
    • (1996) RNA , vol.2 , pp. 110-117
    • Anderson, A.C.1    Scaringe, S.A.2    Earp, B.E.3    Frederick, C.A.4
  • 39
    • 0032855035 scopus 로고    scopus 로고
    • High-performance liquid chromatography purification of homogenous-length RNA produced by trans cleavage with a hammerhead ribozyme
    • Shields, T. P.; Mollova, E.; Ste Marie, L.; Hansen, M. R.; Pardi, A. High-performance liquid chromatography purification of homogenous-length RNA produced by trans cleavage with a hammerhead ribozyme. RNA 1999, 5, 1259-1267.
    • (1999) RNA , vol.5 , pp. 1259-1267
    • Shields, T.P.1    Mollova, E.2    Ste Marie, L.3    Hansen, M.R.4    Pardi, A.5
  • 40
    • 0342601355 scopus 로고    scopus 로고
    • Structure of an RNA hairpin loop with a 5′-CGUUUCG-3′ loop motif by heteronuclear NMR spectroscopy and distance geometry
    • Sich, C.; Ohlenschlager, O.; Ramachandran, R.; Gorlach, M.; Brown, L. R. Structure of an RNA hairpin loop with a 5′-CGUUUCG-3′ loop motif by heteronuclear NMR spectroscopy and distance geometry. Biochemistry 1997, 36, 13989-4002.
    • (1997) Biochemistry , vol.36 , pp. 13989-14002
    • Sich, C.1    Ohlenschlager, O.2    Ramachandran, R.3    Gorlach, M.4    Brown, L.R.5
  • 41
    • 0035864172 scopus 로고    scopus 로고
    • RNA analysis by ion-pair reversed-phase high performance liquid chromatography
    • Azarani, A.; Hecker, K. H. RNA analysis by ion-pair reversed-phase high performance liquid chromatography. Nucleic Acids Res. 2001, 29, e7.
    • (2001) Nucleic Acids Res , vol.29
    • Azarani, A.1    Hecker, K.H.2
  • 42
    • 0036219133 scopus 로고    scopus 로고
    • RNA footprinting analysis using ion pair reverse phase liquid chromatography
    • Dickman, M. J.; Conroy, M. J.; Grasby, J. A.; Hornby, D. P. RNA footprinting analysis using ion pair reverse phase liquid chromatography. RNA 2002, 8, 247-251.
    • (2002) RNA , vol.8 , pp. 247-251
    • Dickman, M.J.1    Conroy, M.J.2    Grasby, J.A.3    Hornby, D.P.4
  • 43
    • 0026611261 scopus 로고
    • Preparation of 13C and 15N labelled RNAs for heteronuclear multi-dimensional NMR studies
    • Nikonowicz, E. P.; Sirr, A.; Legault, P.; Jucker, F. M.; Baer, L. M.; Pardi, A. Preparation of 13C and 15N labelled RNAs for heteronuclear multi-dimensional NMR studies. Nucleic Acids Res. 1992, 20,4507-4513.
    • (1992) Nucleic Acids Res , vol.20 , pp. 4507-4513
    • Nikonowicz, E.P.1    Sirr, A.2    Legault, P.3    Jucker, F.M.4    Baer, L.M.5    Pardi, A.6
  • 44
    • 0026744912 scopus 로고
    • Preparation of isotopically labeled ribonucleotides for multidimensional NMR spectroscopy of RNA
    • Batey, R.T.; Inada, M.; Kujawinski, E.; Puglisi, J.D.; Williamson, J.R. Preparation of isotopically labeled ribonucleotides for multidimensional NMR spectroscopy of RNA. Nucleic Acids Res. 1992, 20, 4515-4523.
    • (1992) Nucleic Acids Res , vol.20 , pp. 4515-4523
    • Batey, R.T.1    Inada, M.2    Kujawinski, E.3    Puglisi, J.D.4    Williamson, J.R.5
  • 45
    • 18144435106 scopus 로고    scopus 로고
    • Rapid preparation of RNA samples for NMR spectroscopy and X-ray crystallography
    • Cheong, H.K.; Hwang, E.; Lee, C.; Choi, B.S.; Cheong, C. Rapid preparation of RNA samples for NMR spectroscopy and X-ray crystallography. Nucleic Acids Res. 2004, 32, e84.
    • (2004) Nucleic Acids Res , vol.32
    • Cheong, H.K.1    Hwang, E.2    Lee, C.3    Choi, B.S.4    Cheong, C.5
  • 46
    • 2442638925 scopus 로고    scopus 로고
    • A general method for rapid and nondenaturing purification of RNAs
    • Kieft, J.S.; Batey, RT. A general method for rapid and nondenaturing purification of RNAs. RNA 2004, 10, 988-995.
    • (2004) RNA , vol.10 , pp. 988-995
    • Kieft, J.S.1    Batey, R.T.2
  • 47
    • 34447527363 scopus 로고    scopus 로고
    • Improved native affinity purification of RNA
    • Batey, R.T.; Kieft, J.S. Improved native affinity purification of RNA. RNA 2007, 13, 1384-1389.
    • (2007) RNA , vol.13 , pp. 1384-1389
    • Batey, R.T.1    Kieft, J.S.2
  • 48
    • 0028248993 scopus 로고
    • 6xHis-Ni-NTA chromatography as a superior technique in recombinant protein expression/purification
    • Crowe, J.; Döbeli, H.; Gentz, R.; Hochuli, E.; Stüber, D.; Henco, K. 6xHis-Ni-NTA chromatography as a superior technique in recombinant protein expression/purification. Methods Mol. Biol. 1994, 31, 371-387.
    • (1994) Methods Mol. Biol , vol.31 , pp. 371-387
    • Crowe, J.1    Döbeli, H.2    Gentz, R.3    Hochuli, E.4    Stüber, D.5    Henco, K.6
  • 49
    • 1642586299 scopus 로고    scopus 로고
    • Control of gene expression by a natural metabolite-responsive ribozyme
    • Winkler, W.C.; Nahvi, A.; Roth, A.; Collins, JA. Breaker, R.R. Control of gene expression by a natural metabolite-responsive ribozyme. Nature 2004, 428, 281-286.
    • (2004) Nature , vol.428 , pp. 281-286
    • Winkler, W.C.1    Nahvi, A.2    Roth, A.3    Collins, J.A.4    Breaker, R.R.5
  • 50
    • 33746920364 scopus 로고    scopus 로고
    • Evidence for preorganization of the glmS ribozyme ligand binding pocket
    • Hampel, K. J.; Tinsley, M. M. Evidence for preorganization of the glmS ribozyme ligand binding pocket. Biochemistry 2006, 45, 7861-7871.
    • (2006) Biochemistry , vol.45 , pp. 7861-7871
    • Hampel, K.J.1    Tinsley, M.M.2
  • 51
    • 1942501609 scopus 로고    scopus 로고
    • Large-scale preparation and purification of polyacrylamide-free RNA oligonucleotides
    • Lukavsky, P.J.; Puglisi, J.D. Large-scale preparation and purification of polyacrylamide-free RNA oligonucleotides. RNA 2004, 10, 889-893.
    • (2004) RNA , vol.10 , pp. 889-893
    • Lukavsky, P.J.1    Puglisi, J.D.2
  • 52
    • 33846446409 scopus 로고    scopus 로고
    • Rapid purification of RNAs using fast performance liquid chromatography (FPLC)
    • Kim, I.; McKenna, S.A.; Viani-Puglisi, E.; Puglisi, J.D. Rapid purification of RNAs using fast performance liquid chromatography (FPLC). RNA 2007, 13, 289-294.
    • (2007) RNA , vol.13 , pp. 289-294
    • Kim, I.1    McKenna, S.A.2    Viani-Puglisi, E.3    Puglisi, J.D.4
  • 54
    • 0027529636 scopus 로고
    • Selective isotopic enrichment of synthetic RNA: Application to the HIV-1 TAR element
    • Michnicka, M. J.; Harper, J. W.; King, G. C. Selective isotopic enrichment of synthetic RNA: application to the HIV-1 TAR element. Biochemistry 1993, 32, 395-400.
    • (1993) Biochemistry , vol.32 , pp. 395-400
    • Michnicka, M.J.1    Harper, J.W.2    King, G.C.3
  • 56
    • 0025193295 scopus 로고
    • Biosynthetic incorporation of 15N and 13C for assignment and interpretation of nuclear magnetic resonance spectra of proteins
    • Mcintosh, L. P.; Dahlquist, F. W. Biosynthetic incorporation of 15N and 13C for assignment and interpretation of nuclear magnetic resonance spectra of proteins. Q. Rev. Biophys. 1990, 23, 1-38.
    • (1990) Q. Rev. Biophys , vol.23 , pp. 1-38
    • Mcintosh, L.P.1    Dahlquist, F.W.2
  • 57
    • 0031114540 scopus 로고    scopus 로고
    • Assignment methodology for larger RNA oligonucleotides: Application to an ATP-binding RNA aptamer
    • Dieckmann, T.; Feigon, J. Assignment methodology for larger RNA oligonucleotides: application to an ATP-binding RNA aptamer. J Biomol NMR 1997, 9, 259-272.
    • (1997) J Biomol NMR , vol.9 , pp. 259-272
    • Dieckmann, T.1    Feigon, J.2
  • 58
    • 0028885514 scopus 로고
    • Multidimensional heteronuclear NMR experiments for structure determination of isotopically labeled RNA
    • Pardi, A. Multidimensional heteronuclear NMR experiments for structure determination of isotopically labeled RNA. Methods Enzymol. 1995, 261, 350-380.
    • (1995) Methods Enzymol , vol.261 , pp. 350-380
    • Pardi, A.1
  • 59
    • 24744459633 scopus 로고    scopus 로고
    • NMR methods for studying the structure and dynamics of RNA
    • Latham, M.P.; Brown, D.J.; McCallum, S.A.; Pardi, A. NMR methods for studying the structure and dynamics of RNA. Chembiochem. 2005, 6, 1492-1505.
    • (2005) Chembiochem , vol.6 , pp. 1492-1505
    • Latham, M.P.1    Brown, D.J.2    McCallum, S.A.3    Pardi, A.4
  • 60
    • 0029800791 scopus 로고    scopus 로고
    • Improved large scale culture of Methylophilus methylotrophus for 13C/15N labeling and random fractional deuteration of ribonucleotides
    • Batey, R. T.; Cloutier, N.; Mao, H.; Williamson, J. R. Improved large scale culture of Methylophilus methylotrophus for 13C/15N labeling and random fractional deuteration of ribonucleotides. Nucleic Acids Res. 1996, 24, 4836-4837.
    • (1996) Nucleic Acids Res , vol.24 , pp. 4836-4837
    • Batey, R.T.1    Cloutier, N.2    Mao, H.3    Williamson, J.R.4
  • 61
    • 1442286437 scopus 로고    scopus 로고
    • NMR structure of the 101-nucleotide core encapsidation signal of the Moloney murine leukemia virus
    • D'Souza, V.; Dey, A.; Habib, D.; Summers, M.F. NMR structure of the 101-nucleotide core encapsidation signal of the Moloney murine leukemia virus. J. Mol. Biol. 2004, 337, 427-442.
    • (2004) J. Mol. Biol , vol.337 , pp. 427-442
    • D'Souza, V.1    Dey, A.2    Habib, D.3    Summers, M.F.4
  • 62
    • 1242340502 scopus 로고    scopus 로고
    • New applications of 2D filtered/edited NOESY for assignment and structure elucidation of RNA and RNA-protein complexes
    • Peterson, R. D.; Theimer, C. A.; Wu, H.; Feigon, J. New applications of 2D filtered/edited NOESY for assignment and structure elucidation of RNA and RNA-protein complexes. J. Biomol. NMR 2004, 28, 59-67.
    • (2004) J. Biomol. NMR , vol.28 , pp. 59-67
    • Peterson, R.D.1    Theimer, C.A.2    Wu, H.3    Feigon, J.4
  • 63
    • 85047669369 scopus 로고
    • Preparation of carbon-13 labeled ribonucleotides using acetate as an isotope source
    • Hoffman, D.W.; Holland, J.A. Preparation of carbon-13 labeled ribonucleotides using acetate as an isotope source. Nucleic Acids Res. 1995, 23, 3361-3362.
    • (1995) Nucleic Acids Res , vol.23 , pp. 3361-3362
    • Hoffman, D.W.1    Holland, J.A.2
  • 64
    • 33747880448 scopus 로고    scopus 로고
    • Alternate-site isotopic labeling of ribonucleotides for NMR studies of ribose conformational dynamics in RNA
    • Johnson, J.E. Jr.; Julien, K.R.; Hoogstraten, C.G. Alternate-site isotopic labeling of ribonucleotides for NMR studies of ribose conformational dynamics in RNA. J. Biomol. NMR 2006, 35, 261-274.
    • (2006) J. Biomol. NMR , vol.35 , pp. 261-274
    • Johnson Jr., J.E.1    Julien, K.R.2    Hoogstraten, C.G.3
  • 65
    • 38949194231 scopus 로고    scopus 로고
    • Metabolic labeling: Taking advantage of bacterial pathways to prepare spectroscopically useful isotope patterns in proteins and nucleic acids
    • Hoogstraten, C. G.; Johnson, J.E. Jr. Metabolic labeling: Taking advantage of bacterial pathways to prepare spectroscopically useful isotope patterns in proteins and nucleic acids. Concepts in Magnetic Resonance Part A 2008, 32A, 34-55.
    • (2008) Concepts in Magnetic Resonance Part A , vol.32 A , pp. 34-55
    • Hoogstraten, C.G.1    Johnson Jr., J.E.2
  • 67
    • 0014424848 scopus 로고
    • High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease
    • Markley, J.L.; Putter, I.; Jardetzky, O. High-resolution nuclear magnetic resonance spectra of selectively deuterated staphylococcal nuclease. Science 1968, 161, 1249-1251.
    • (1968) Science , vol.161 , pp. 1249-1251
    • Markley, J.L.1    Putter, I.2    Jardetzky, O.3
  • 68
    • 0025269342 scopus 로고
    • Deuterium labelling in NMR structural analysis of larger proteins
    • LeMaster, D.M. Deuterium labelling in NMR structural analysis of larger proteins. Q. Rev. Biophys. 1990, 23, 133-174.
    • (1990) Q. Rev. Biophys , vol.23 , pp. 133-174
    • LeMaster, D.M.1
  • 69
    • 0028520420 scopus 로고
    • Effect of deuteration on the amide proton relaxation rates in proteins. Heteronuclear NMR experiments on villin 14T
    • Markus, M.A.; Dayie, K.T.; Matsudaira, P.; Wagner, G. Effect of deuteration on the amide proton relaxation rates in proteins. Heteronuclear NMR experiments on villin 14T. J. Magn. Reson. B. 1994, 105, 192-195.
    • (1994) J. Magn. Reson. B , vol.105 , pp. 192-195
    • Markus, M.A.1    Dayie, K.T.2    Matsudaira, P.3    Wagner, G.4
  • 70
    • 0031576691 scopus 로고    scopus 로고
    • 13C-Labeled RNA for NMR Studies Using Enzymatic Synthesis
    • 13C-Labeled RNA for NMR Studies Using Enzymatic Synthesis. J. Am. Chem. Soc. 1997, 119, 12100-12108.
    • (1997) J. Am. Chem. Soc , vol.119 , pp. 12100-12108
    • Tolbert, T.J.1    Williamson, J.R.2
  • 72
    • 0031595590 scopus 로고    scopus 로고
    • 15N multidimensional NMR to study the structure and dynamics of proteins
    • 15N multidimensional NMR to study the structure and dynamics of proteins. Annu. Rev. Biophys. Biomol. Struct. 1998, 27, 357-406.
    • (1998) Annu. Rev. Biophys. Biomol. Struct , vol.27 , pp. 357-406
    • Gardner, K.H.1    Kay, L.E.2
  • 73
    • 0035223403 scopus 로고    scopus 로고
    • 2H-labeled RNA oligonucleotides in nuclear magnetic resonance studies
    • 2H-labeled RNA oligonucleotides in nuclear magnetic resonance studies. Methods Enzymol. 2001, 338, 320-341.
    • (2001) Methods Enzymol , vol.338 , pp. 320-341
    • Nikonowicz, E.P.1
  • 75
    • 22444437410 scopus 로고    scopus 로고
    • RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex
    • Davis, J.H.; Tonelli, M.; Scott, L.G.; Jaeger, L.; Williamson, J.R.; Butcher, S.E. RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex. J. Mol. Biol. 2005, 351, 371-382.
    • (2005) J. Mol. Biol , vol.351 , pp. 371-382
    • Davis, J.H.1    Tonelli, M.2    Scott, L.G.3    Jaeger, L.4    Williamson, J.R.5    Butcher, S.E.6
  • 76
    • 48649108036 scopus 로고    scopus 로고
    • Erratum in: J. Mol. Biol. 2006, 360, 742.
    • Erratum in: J. Mol. Biol. 2006, 360, 742.
  • 77
    • 0029836175 scopus 로고    scopus 로고
    • Preparation of Specifically Deuterated RNA for NMR Studies Using a Combination of Chemical and Enzymatic Synthesis
    • Tolbert, T.J.; Williamson, J.R. Preparation of Specifically Deuterated RNA for NMR Studies Using a Combination of Chemical and Enzymatic Synthesis. J. Am. Chem. Soc. 1996, 118, 7929-7940.
    • (1996) J. Am. Chem. Soc , vol.118 , pp. 7929-7940
    • Tolbert, T.J.1    Williamson, J.R.2
  • 79
    • 0000689621 scopus 로고
    • Synthesis of phosphoenolypyruvate and its use in ATP cofactor regeneration
    • Hirschbein, B.L.; Mazenod, F.P.; Whitesides, G.M. Synthesis of phosphoenolypyruvate and its use in ATP cofactor regeneration. J. Org. Chem. 1982, 47, 3765-3766.
    • (1982) J. Org. Chem , vol.47 , pp. 3765-3766
    • Hirschbein, B.L.1    Mazenod, F.P.2    Whitesides, G.M.3
  • 80
    • 0024829415 scopus 로고
    • Preparation of phosphoenolpyruvate from D-(-)-3-phosphoglyceric acid for use in regeneration of ATP
    • Simon, E.S.; Grabowski, S.; Whitesides, G.M. Preparation of phosphoenolpyruvate from D-(-)-3-phosphoglyceric acid for use in regeneration of ATP. J. Am. Chem. Soc. 1989, 111, 8920-8921.
    • (1989) J. Am. Chem. Soc , vol.111 , pp. 8920-8921
    • Simon, E.S.1    Grabowski, S.2    Whitesides, G.M.3
  • 81
    • 0028087716 scopus 로고
    • Enzymic Synthesis of NAD+ with the Specific Incorporation of Atomic Labels
    • Rising, K.A.; Schramm, V.L. Enzymic Synthesis of NAD+ with the Specific Incorporation of Atomic Labels. J. Am. Chem. Soc. 1994, 116, 6531-6536.
    • (1994) J. Am. Chem. Soc , vol.116 , pp. 6531-6536
    • Rising, K.A.1    Schramm, V.L.2
  • 83
    • 36849007038 scopus 로고    scopus 로고
    • Synthesis of 5-fluoropyrimidine nucleotides as sensitive NMR probes of RNA structure
    • Hennig, M.; Scott, L.G.; Sperling, E.; Bermel, W.; Williamson, J.R. Synthesis of 5-fluoropyrimidine nucleotides as sensitive NMR probes of RNA structure. J. Am. Chem. Soc. 2007, 129, 14911-14921.
    • (2007) J. Am. Chem. Soc , vol.129 , pp. 14911-14921
    • Hennig, M.1    Scott, L.G.2    Sperling, E.3    Bermel, W.4    Williamson, J.R.5
  • 84
    • 36549045524 scopus 로고    scopus 로고
    • Molecular replacement
    • Toth, EA. Molecular replacement. Methods Mol. Biol. 2007, 364, 121-148.
    • (2007) Methods Mol. Biol , vol.364 , pp. 121-148
    • Toth, E.A.1
  • 85
    • 0029856189 scopus 로고    scopus 로고
    • X-ray crystallography of large RNAs: Heavy-atom derivatives by RNA engineering
    • Golden, B. L.; Gooding, A. R.; Podell, E. R.; Cech, T. R X-ray crystallography of large RNAs: heavy-atom derivatives by RNA engineering. RNA 1996, 2, 1295-1305.
    • (1996) RNA , vol.2 , pp. 1295-1305
    • Golden, B.L.1    Gooding, A.R.2    Podell, E.R.3    Cech, T.R.4
  • 86
    • 0034086512 scopus 로고    scopus 로고
    • Heavy atom derivatives of RNA
    • Golden, B. L. Heavy atom derivatives of RNA. Methods Enzymol. 2000, 317, 124-132.
    • (2000) Methods Enzymol , vol.317 , pp. 124-132
    • Golden, B.L.1
  • 87
    • 0034089091 scopus 로고    scopus 로고
    • Purification, crystallization, and X-ray diffraction analysis of small ribozymes
    • Wedekind, J. E.; McKay, D. B. Purification, crystallization, and X-ray diffraction analysis of small ribozymes. Methods Enzymol. 2000, 317, 149-168.
    • (2000) Methods Enzymol , vol.317 , pp. 149-168
    • Wedekind, J.E.1    McKay, D.B.2
  • 88
    • 0030781084 scopus 로고    scopus 로고
    • Use of chemically modified nucleotides to determine a 62-nucleotide RNA crystal structure: A survey of phosphorothioates, Br, Pt and Hg
    • Correll, C. C.; Freeborn, B.; Moore, P. B.; Steitz, T. A. Use of chemically modified nucleotides to determine a 62-nucleotide RNA crystal structure: a survey of phosphorothioates, Br, Pt and Hg. J. Biomol. Struct. Dyn. 1997, 15, 165-172.
    • (1997) J. Biomol. Struct. Dyn , vol.15 , pp. 165-172
    • Correll, C.C.1    Freeborn, B.2    Moore, P.B.3    Steitz, T.A.4
  • 89
    • 0034604296 scopus 로고    scopus 로고
    • 2.8 A crystal structure of the malachite green aptamer
    • Baugh, C.; Grate, D.; Wilson, C. 2.8 A crystal structure of the malachite green aptamer. J. Mol. Biol. 2000, 301, 117-128.
    • (2000) J. Mol. Biol , vol.301 , pp. 117-128
    • Baugh, C.1    Grate, D.2    Wilson, C.3
  • 90
    • 33746228126 scopus 로고    scopus 로고
    • Tertiary contacts distant from the active site prime a ribozyme for catalysis
    • Martick, M.; Scott, W. G., Tertiary contacts distant from the active site prime a ribozyme for catalysis. Cell 2006, 126, 309-320.
    • (2006) Cell , vol.126 , pp. 309-320
    • Martick, M.1    Scott, W.G.2
  • 91
    • 0034695419 scopus 로고    scopus 로고
    • Crystallization and structure determination of a hepatitis delta virus ribozyme: Use of the RNA-binding protein UIA as a crystallization module
    • Ferre-D'Amare, A. R.; Doudna, J. A., Crystallization and structure determination of a hepatitis delta virus ribozyme: use of the RNA-binding protein UIA as a crystallization module. J. Mol. Biol. 2000, 295, 541-556.
    • (2000) J. Mol. Biol , vol.295 , pp. 541-556
    • Ferre-D'Amare, A.R.1    Doudna, J.A.2
  • 92
    • 0032497521 scopus 로고    scopus 로고
    • Crystal structure of a hepatitis delta virus ribozyme
    • Ferre-D'Amare, A. R.; Zhou, K.; Doudna, J. A., Crystal structure of a hepatitis delta virus ribozyme. Nature 1998, 395, 567-574.
    • (1998) Nature , vol.395 , pp. 567-574
    • Ferre-D'Amare, A.R.1    Zhou, K.2    Doudna, J.A.3
  • 93
    • 41649093743 scopus 로고    scopus 로고
    • Selenium Derivatization of Nucleic Acids for Phase and Structure Determination in Nucleic Acid X-ray Crystallography
    • Sheng, J.; Huang, Z. Selenium Derivatization of Nucleic Acids for Phase and Structure Determination in Nucleic Acid X-ray Crystallography. Int. J. Mol. Sci. 2008, 9, 258-271.
    • (2008) Int. J. Mol. Sci , vol.9 , pp. 258-271
    • Sheng, J.1    Huang, Z.2
  • 94
    • 33746267483 scopus 로고    scopus 로고
    • Efficient substrate cleavage catalyzed by hammerhead ribozymes derivatized with selenium for X-ray crystallography
    • Brandt, G.; Carrasco, N.; Huang, Z. Efficient substrate cleavage catalyzed by hammerhead ribozymes derivatized with selenium for X-ray crystallography. Biochemistry 2006, 45, 8972-8977.
    • (2006) Biochemistry , vol.45 , pp. 8972-8977
    • Brandt, G.1    Carrasco, N.2    Huang, Z.3
  • 95
    • 34447260753 scopus 로고    scopus 로고
    • A general strategy to solve the phase problem in RNA crystallography
    • Keel, A.Y.; Rambo, R.P.; Batey, R.T.; Kieft, J.S. A general strategy to solve the phase problem in RNA crystallography. Structure 2007, 15, 761-772.
    • (2007) Structure , vol.15 , pp. 761-772
    • Keel, A.Y.1    Rambo, R.P.2    Batey, R.T.3    Kieft, J.S.4
  • 96
    • 0024282471 scopus 로고
    • Chemical reactions within DNA duplexes. Cyanogen bromide as an effective oligodeoxyribonucleotide coupling agent
    • Sokolova, N.I.; Ashirbekova, D.T.; Dolinnaya, N.G.; Shabarova, Z.A. Chemical reactions within DNA duplexes. Cyanogen bromide as an effective oligodeoxyribonucleotide coupling agent. FEBS Lett. 1988, 232, 153-155.
    • (1988) FEBS Lett , vol.232 , pp. 153-155
    • Sokolova, N.I.1    Ashirbekova, D.T.2    Dolinnaya, N.G.3    Shabarova, Z.A.4
  • 97
    • 0025760436 scopus 로고
    • The use of BrCN for assembling modified DNA duplexes and DNA-RNA hybrids; comparison with water-soluble carbodiimide
    • Dolinnaya, N.G.; Sokolova, N.I.; Ashirbekova, D.T.; Shabarova, Z.A. The use of BrCN for assembling modified DNA duplexes and DNA-RNA hybrids; comparison with water-soluble carbodiimide. Nucleic Acids Res. 1991, 19, 3067-3072.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3067-3072
    • Dolinnaya, N.G.1    Sokolova, N.I.2    Ashirbekova, D.T.3    Shabarova, Z.A.4
  • 98
    • 36849040522 scopus 로고    scopus 로고
    • A novel approach to the synthesis of DNA and RNA lariats
    • Mitra, D.; Damha, M.J. A novel approach to the synthesis of DNA and RNA lariats. J. Org. Chem. 2007, 72, 9491-9500.
    • (2007) J. Org. Chem , vol.72 , pp. 9491-9500
    • Mitra, D.1    Damha, M.J.2
  • 99
    • 0034131335 scopus 로고    scopus 로고
    • Joining of RNAs by splinted ligation
    • Moore, M.J.; Query, C.C. Joining of RNAs by splinted ligation. Methods Enzymol. 2000, 317, 109-123.
    • (2000) Methods Enzymol , vol.317 , pp. 109-123
    • Moore, M.J.1    Query, C.C.2
  • 100
    • 0020971301 scopus 로고
    • Joining of RNA molecules with RNA ligase
    • Romaniuk, P.J.; Uhlenbeck, O.C. Joining of RNA molecules with RNA ligase. Methods Enzymol. 1983, 100, 52-59.
    • (1983) Methods Enzymol , vol.100 , pp. 52-59
    • Romaniuk, P.J.1    Uhlenbeck, O.C.2
  • 101
    • 38449121473 scopus 로고    scopus 로고
    • Preparation of large RNA oligonucleotides with complementary isotope-labeled segments for NMR structural studies
    • Tzakos, A.G.; Easton, L.E.; Lukavsky, P.J. Preparation of large RNA oligonucleotides with complementary isotope-labeled segments for NMR structural studies. Nat. Protoc. 2007, 2, 2139-2147.
    • (2007) Nat. Protoc , vol.2 , pp. 2139-2147
    • Tzakos, A.G.1    Easton, L.E.2    Lukavsky, P.J.3
  • 102
    • 33751118289 scopus 로고    scopus 로고
    • An RNA ligase-mediated method for the efficient creation of large, synthetic RNAs
    • Stark, M.R.; Pleiss, J.A.; Deras, M.; Scaringe, S.A.; Rader, S.D. An RNA ligase-mediated method for the efficient creation of large, synthetic RNAs. RNA 2006, 12, 2014-2019.
    • (2006) RNA , vol.12 , pp. 2014-2019
    • Stark, M.R.1    Pleiss, J.A.2    Deras, M.3    Scaringe, S.A.4    Rader, S.D.5
  • 103
    • 0037077562 scopus 로고    scopus 로고
    • NMR study of 100 kDa HCV IRES RNA using segmental isotope labeling
    • Kim, I.; Lukavsky, P.J.; Puglisi, J.D. NMR study of 100 kDa HCV IRES RNA using segmental isotope labeling. J. Am. Chem. Soc. 2002, 124, 9338-9339.
    • (2002) J. Am. Chem. Soc , vol.124 , pp. 9338-9339
    • Kim, I.1    Lukavsky, P.J.2    Puglisi, J.D.3
  • 104
    • 0026687314 scopus 로고
    • Regioselective ligation of oligoribonucleotides using DNA splints
    • Bain, J.D.; Switzer, C. Regioselective ligation of oligoribonucleotides using DNA splints. Nucleic Acids Res. 1992, 20, 4372.
    • (1992) Nucleic Acids Res , vol.20 , pp. 4372
    • Bain, J.D.1    Switzer, C.2
  • 105
    • 37549019376 scopus 로고    scopus 로고
    • Recent advances in DNA catalysis
    • Höbartner, C.; Silverman, S.K. Recent advances in DNA catalysis. Biopolymers 2007, 87, 279-292.
    • (2007) Biopolymers , vol.87 , pp. 279-292
    • Höbartner, C.1    Silverman, S.K.2
  • 106
    • 25444501848 scopus 로고    scopus 로고
    • General deoxyribozyme-catalyzed synthesis of native 3′-5′ RNA linkages
    • Purtha, W.E.; Coppins, R.L.; Smalley, M.K.; Silverman, S.K. General deoxyribozyme-catalyzed synthesis of native 3′-5′ RNA linkages. J. Am. Chem. Soc. 2005, 127, 13124-13125.
    • (2005) J. Am. Chem. Soc , vol.127 , pp. 13124-13125
    • Purtha, W.E.1    Coppins, R.L.2    Smalley, M.K.3    Silverman, S.K.4
  • 107
    • 20344368389 scopus 로고    scopus 로고
    • How retroviruses select their genomes
    • D'Souza, V.; Summers, M.F. How retroviruses select their genomes. Nat. Rev. Microbiol. 2005, 3, 643-655.
    • (2005) Nat. Rev. Microbiol , vol.3 , pp. 643-655
    • D'Souza, V.1    Summers, M.F.2
  • 108
    • 4944256277 scopus 로고    scopus 로고
    • Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus
    • D'Souza, V.; Summers, M.F. Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus. Nature 2004, 431, 586-590.
    • (2004) Nature , vol.431 , pp. 586-590
    • D'Souza, V.1    Summers, M.F.2
  • 109
    • 27844569938 scopus 로고    scopus 로고
    • Group II introns: Ribozymes that splice RNA and invade DNA
    • Gesteland, R.F, Cech, T.R, Atkins, J.F, Eds Cold Spring Harbor Laboratory Press: New York, 3rd Ed, Chapter 17, p
    • rd Ed., Chapter 17, p 469.
    • (2006) RNA World , pp. 469
    • Pyle, A.M.1    Lambowitz, A.M.2
  • 110
    • 33748163502 scopus 로고    scopus 로고
    • Fluorescence and solution NMR study of the active site of a 160-kDa group II intron ribozyme
    • Gumbs, O.H.; Padgett, R.A.; Dayie, K.T. Fluorescence and solution NMR study of the active site of a 160-kDa group II intron ribozyme. RNA 2006, 12, 1693-1707.
    • (2006) RNA , vol.12 , pp. 1693-1707
    • Gumbs, O.H.1    Padgett, R.A.2    Dayie, K.T.3
  • 111
    • 31044440894 scopus 로고    scopus 로고
    • Structure of a self-splicing group II intron catalytic effector domain 5: Parallels with spliceosomal U6 RNA
    • Seetharaman, M.; Eldho, N.V.; Padgett, R.A.; Dayie, K.T. Structure of a self-splicing group II intron catalytic effector domain 5: parallels with spliceosomal U6 RNA. RNA 2006, 12, 235-247.
    • (2006) RNA , vol.12 , pp. 235-247
    • Seetharaman, M.1    Eldho, N.V.2    Padgett, R.A.3    Dayie, K.T.4
  • 112
    • 33845771847 scopus 로고    scopus 로고
    • Internal bulge and tetraloop of the catalytic domain 5 of a group II intron ribozyme are flexible: Implications for catalysis
    • Eldho, N.V.; Dayie, K.T. Internal bulge and tetraloop of the catalytic domain 5 of a group II intron ribozyme are flexible: implications for catalysis. J Mol Biol. 2007, 365, 930-944.
    • (2007) J Mol Biol , vol.365 , pp. 930-944
    • Eldho, N.V.1    Dayie, K.T.2
  • 114
    • 35548979485 scopus 로고    scopus 로고
    • Substitution of the use of radioactivity by fluorescence for biochemical studies of RNA
    • Ying, B. W.; Fourmy, D.; Yoshizawa, S. Substitution of the use of radioactivity by fluorescence for biochemical studies of RNA. RNA 2007, 13, 2042-2050.
    • (2007) RNA , vol.13 , pp. 2042-2050
    • Ying, B.W.1    Fourmy, D.2    Yoshizawa, S.3
  • 115
    • 34347264055 scopus 로고    scopus 로고
    • Solution NMR studies of the maturation intermediates of a 13 MDa viral capsid
    • Szymczyna, B.R.; Gan, L.; Johnson, J.E.; Williamson, J.R Solution NMR studies of the maturation intermediates of a 13 MDa viral capsid. J. Am. Chem. Soc. 2007, 129, 7867-7876.
    • (2007) J. Am. Chem. Soc , vol.129 , pp. 7867-7876
    • Szymczyna, B.R.1    Gan, L.2    Johnson, J.E.3    Williamson, J.R.4
  • 116
    • 41749109563 scopus 로고    scopus 로고
    • Crystal structure of a self-spliced group II intron
    • Toor, N.; Keating, K S.; Taylor, S. D.; Pyle, A. M. Crystal structure of a self-spliced group II intron. Science 2008, 320, 77-82.
    • (2008) Science , vol.320 , pp. 77-82
    • Toor, N.1    Keating, K.S.2    Taylor, S.D.3    Pyle, A.M.4
  • 117
    • 48649104354 scopus 로고    scopus 로고
    • A glimpse into the active site of the Group II intron and maybe the spliceosome too
    • in Press
    • Dayie, K.T.; Padgett, R.A. A glimpse into the active site of the Group II intron and maybe the spliceosome too. RNA, 2008, in Press.
    • (2008) RNA
    • Dayie, K.T.1    Padgett, R.A.2


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