Troglitazone but not conjugated linoleic acid reduces gene expression and activity of matrix-metalloproteinases-2 and -9 in PMA-differentiated THP-1 macrophages

Journal of Nutritional Biochemistry

Volumn 19, Issue 9, 2008, Pages 594-603

  Ringseis, Robert ^a   Schulz, Nadja ^a   Saal, Daniela ^a   Eder, Klaus ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Atherosclerosis; Conjugated linoleic acid; Macrophages; Matrix metalloproteinase; NF B; Peroxisome proliferator activated receptor

Indexed keywords

CONJUGATED LINOLEIC ACID; DNA; FATTY ACID; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LINOLEIC ACID; LIPID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHORBOL 13 ACETATE 12 MYRISTATE; TROGLITAZONE;

ARTICLE; ATHEROSCLEROTIC PLAQUE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEGRADATION; DISEASE COURSE; DNA BINDING; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; ISOMER; LEUKEMIA CELL; MACROPHAGE; MYELOID LEUKEMIA; STATISTICAL SIGNIFICANCE; TRANSACTIVATION;

CELL SURVIVAL; CELLS, CULTURED; CHROMANS; GENE EXPRESSION; HUMANS; LINOLEIC ACIDS, CONJUGATED; LIPID METABOLISM; MACROPHAGES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NF-KAPPA B; PPAR GAMMA; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; THIAZOLIDINEDIONES; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 48649087711     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.08.003     Document Type: Article

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