Anti-tumor activity of N-thiolated β-lactam antibiotics

Cancer Letters

Volumn 268, Issue 1, 2008, Pages 63-69

  Chen, Di ^a   Falsetti, Samuel C ^b   Frezza, Michael ^a   Milacic, Vesna ^a   Kazi, Aslamuzzaman ^b   Cui, Qiuzhi Cindy ^a   Long, Timothy E ^c   Turos, Edward ^c   Dou, Q Ping ^a  

^a KARMANOS CANCER INSTITUTE   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c Center for Molecular Diversity in Drug Design Discovery and Delivery   (United States)

Author keywords

Lactam; Anti tumor activity; Apoptosis; Breast cancer; DNA damage

Indexed keywords

BETA LACTAM ANTIBIOTIC; BETA LACTAM L1; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HEAT SHOCK PROTEIN 70;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST TUMOR; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DRUG STRUCTURE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MOUSE; NICK END LABELING; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL ANALYSIS; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIGENS, DIFFERENTIATION; APOPTOSIS; BREAST NEOPLASMS; DNA DAMAGE; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; JURKAT CELLS; MICE; MICE, NUDE; MONOBACTAMS; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 48349148109     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.03.047     Document Type: Article

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