A novel β-lactam antibiotic activates tumor cell apoptotic program by inducing DNA damage

Molecular Pharmacology

Volumn 61, Issue 6, 2002, Pages 1348-1358

  Smith, David M ^a,b   Kazi, Aslamuzzaman ^a   Smith, Lisa ^a   Long, Timothy E ^a,c   Heldreth, Bart ^a,c   Turos, Edward ^a,c   Ping Dou, Q ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; PROTEIN BID; SYNAPTOPHYSIN;

APOPTOSIS; ARTICLE; BREAST CANCER; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVATION; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROSTATE CANCER; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

ANTI-BACTERIAL AGENTS; APOPTOSIS; BETA-LACTAMS; CASPASES; CELL DIVISION; CYTOCHROME C GROUP; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVATION; HUMANS; JURKAT CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; S PHASE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0036262532     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.6.1348     Document Type: Article

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