-
1
-
-
0033751632
-
(20M). Severe combined immunodeficiencies (SCID)
-
Fischer, A (20M). Severe combined immunodeficiencies (SCID). Clin Exp Immunol 122: 143-149.
-
Clin Exp Immunol
, vol.122
, pp. 143-149
-
-
Fischer, A.1
-
2
-
-
10144253125
-
RAG mutations in human B cell-negative SCID
-
Schwarz, K, Gauss, GH, Ludwig, L, Pannicke, U, Li, Z, Lindner, D et al. (1996). RAG mutations in human B cell-negative SCID. Science 274: 97-99.
-
(1996)
Science
, vol.274
, pp. 97-99
-
-
Schwarz, K.1
Gauss, G.H.2
Ludwig, L.3
Pannicke, U.4
Li, Z.5
Lindner, D.6
-
3
-
-
0035917489
-
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
-
Moshous, D, Callebaut, I, de Chasseval, R, Comeo, B, Cavazzana-Calvo, M, Le Deist F et al. (2001). Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 105: 177-186.
-
(2001)
Cell
, vol.105
, pp. 177-186
-
-
Moshous, D.1
Callebaut, I.2
de Chasseval, R.3
Comeo, B.4
Cavazzana-Calvo, M.5
Le Deist, F.6
-
4
-
-
23644452672
-
The repair of DNA damages/modifications during the maturation of the immune system: Lessons from human primary immunodeficiency disorders and animal models
-
Revy, P, Buck, D, le Deist, F and de Villartay, JP (2005). The repair of DNA damages/modifications during the maturation of the immune system: lessons from human primary immunodeficiency disorders and animal models. Adv Immunol 87: 237-295.
-
(2005)
Adv Immunol
, vol.87
, pp. 237-295
-
-
Revy, P.1
Buck, D.2
le Deist, F.3
de Villartay, J.P.4
-
5
-
-
0029971123
-
Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts
-
Nicolas, N, Finnie, NJ, Cavazzana-Calvo, M, Papadopoulo, D, Le Deist, F, Fischer, A et al. (1996). Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts. Eur J Immunol 26: 1118-1122.
-
(1996)
Eur J Immunol
, vol.26
, pp. 1118-1122
-
-
Nicolas, N.1
Finnie, N.J.2
Cavazzana-Calvo, M.3
Papadopoulo, D.4
Le Deist, F.5
Fischer, A.6
-
6
-
-
0037809601
-
Novel Artemis gene mutations of radiosensitive severe combined immunodeficiency in Japanese families
-
Kobayashi, N, Agematsu, K, Sugita, K, Sako, M, Nonoyama, S, Yachie, A et al. (2003). Novel Artemis gene mutations of radiosensitive severe combined immunodeficiency in Japanese families. Hum Genet 112 348-352.
-
(2003)
Hum Genet
, vol.112
, pp. 348-352
-
-
Kobayashi, N.1
Agematsu, K.2
Sugita, K.3
Sako, M.4
Nonoyama, S.5
Yachie, A.6
-
7
-
-
0037441592
-
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow
-
Noordzij, JG, Verkaik, NS, van der Burg, M, van Veelen, LR, de Bruin-Versteeg, S, Wiegant, W et al. (2003). Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow. Blood 101: 1446-1452.
-
(2003)
Blood
, vol.101
, pp. 1446-1452
-
-
Noordzij, J.G.1
Verkaik, N.S.2
van der Burg, M.3
van Veelen, L.R.4
de Bruin-Versteeg, S.5
Wiegant, W.6
-
8
-
-
0037312006
-
Partial T and B lymphocyte immunodeficiency and predisposition to lymphorna in patients with hypomorphic mutations in Artemis
-
Moshous, D, Pannetier, C, de Chasseval, R, le Deist, F, Cavazzana-Calvo, M, Romana, S et al. (2003). Partial T and B lymphocyte immunodeficiency and predisposition to lymphorna in patients with hypomorphic mutations in Artemis. J Clin Invest 111: 381-387.
-
(2003)
J Clin Invest
, vol.111
, pp. 381-387
-
-
Moshous, D.1
Pannetier, C.2
de Chasseval, R.3
le Deist, F.4
Cavazzana-Calvo, M.5
Romana, S.6
-
9
-
-
0037442176
-
Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: Report of the European experience 1968-99
-
Antoine, C, Muller, S, Cant, A, Cavazzana-Calvo, M, Veys, P, Vossen, J et al. (2003). Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: Report of the European experience 1968-99. Lancet 361: 553-560.
-
(2003)
Lancet
, vol.361
, pp. 553-560
-
-
Antoine, C.1
Muller, S.2
Cant, A.3
Cavazzana-Calvo, M.4
Veys, P.5
Vossen, J.6
-
10
-
-
0036932453
-
Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice
-
Rooney, S, Sekiguchi, J, Zhu, C, Cheng, HL, Manis, J, Whitlow, S et al. (2002). Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice. Mol Cell 10 1379-1390.
-
(2002)
Mol Cell
, vol.10
, pp. 1379-1390
-
-
Rooney, S.1
Sekiguchi, J.2
Zhu, C.3
Cheng, H.L.4
Manis, J.5
Whitlow, S.6
-
11
-
-
13544259957
-
Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation
-
Li, L, Salido, E, Zhou, Y, Bhattacharyya, S, Yannone, SM, Dunn, E et al. (2005). Targeted disruption of the Artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation. J Immunol 174: 2420-2428.
-
(2005)
J Immunol
, vol.174
, pp. 2420-2428
-
-
Li, L.1
Salido, E.2
Zhou, Y.3
Bhattacharyya, S.4
Yannone, S.M.5
Dunn, E.6
-
12
-
-
0037416138
-
Defective DNA repair and increased genomic instability in Artemis-deficient murine cells
-
Rooney, S, Alt, FW, Lombard, D, Whitlow, S, Eckersdorff, M, Fleming, J et al. (2003). Defective DNA repair and increased genomic instability in Artemis-deficient murine cells. J Exp Med 197 553-565.
-
(2003)
J Exp Med
, vol.197
, pp. 553-565
-
-
Rooney, S.1
Alt, F.W.2
Lombard, D.3
Whitlow, S.4
Eckersdorff, M.5
Fleming, J.6
-
13
-
-
20244376003
-
Damaging-agent sensitivity of Artemis-deficient cell lines
-
Musio, A, Marrella, V, Sobacchi, C, Rucci, F, Fariselli, L, Giliani, S et al. (2005). Damaging-agent sensitivity of Artemis-deficient cell lines. Eur J Immunol 35: 1250-1256.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1250-1256
-
-
Musio, A.1
Marrella, V.2
Sobacchi, C.3
Rucci, F.4
Fariselli, L.5
Giliani, S.6
-
14
-
-
33846021317
-
Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle
-
Darroudi, F, Wiegant, W, Meijers, M, Friedl, AA, van der Burg, M, Fomina, J et al. (2007). Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle. Mutat Res 615: 111-124.
-
(2007)
Mutat Res
, vol.615
, pp. 111-124
-
-
Darroudi, F.1
Wiegant, W.2
Meijers, M.3
Friedl, A.A.4
van der Burg, M.5
Fomina, J.6
-
15
-
-
0034985720
-
Enhanced transgene expression in cord blood CD34(+)-derived hematopoietic cells, including developing T cells and NOD/SCID mouse repopulating cells, following transduction with modified trip lentiviral vectors
-
Sirven, A, Ravet, E, Chameau, P, Zennou, V, Coulombel, L, Guetard, D et al. (2001). Enhanced transgene expression in cord blood CD34(+)-derived hematopoietic cells, including developing T cells and NOD/SCID mouse repopulating cells, following transduction with modified trip lentiviral vectors. Mol Ther 3: 438-448.
-
(2001)
Mol Ther
, vol.3
, pp. 438-448
-
-
Sirven, A.1
Ravet, E.2
Chameau, P.3
Zennou, V.4
Coulombel, L.5
Guetard, D.6
-
16
-
-
0037134031
-
Murine leukemia induced by retroviral gene marking
-
Li, Z, Dullmann, J, Schiedlmeier, B, Schmidt M, von Kalle, C, Meyer, J et al. (2002). Murine leukemia induced by retroviral gene marking. Science 296: 497.
-
(2002)
Science
, vol.296
, pp. 497
-
-
Li, Z.1
Dullmann, J.2
Schiedlmeier, B.3
Schmidt, M.4
von Kalle, C.5
Meyer, J.6
-
17
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina, S, Von Kalle, C, Schmidt M, McCormack, MP, Wulffraat, N, Leboulch, P et al. (2003). LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302: 415-419.
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
McCormack, M.P.4
Wulffraat, N.5
Leboulch, P.6
-
18
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
Wu, X, Li, Y, Crise, B and Burgess, SM (2003). Transcription start regions in the human genome are favored targets for MLV integration. Science 300: 1749-1751.
-
(2003)
Science
, vol.300
, pp. 1749-1751
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
-
19
-
-
25144490586
-
Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells
-
Calmels, B, Ferguson, C, Laukkanen, MO, Adler, R, Faulhaber, M, Kim, HJ et al. (2005). Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells. Blood 106 2530-2533.
-
(2005)
Blood
, vol.106
, pp. 2530-2533
-
-
Calmels, B.1
Ferguson, C.2
Laukkanen, M.O.3
Adler, R.4
Faulhaber, M.5
Kim, H.J.6
-
20
-
-
34249890562
-
Gene therapy for severe combined immunodeficiency. are we there yet?
-
Cavazzana-Calvo, M and Fischer, A (2007). Gene therapy for severe combined immunodeficiency. are we there yet? J Clin Invest 117 1456-1465.
-
(2007)
J Clin Invest
, vol.117
, pp. 1456-1465
-
-
Cavazzana-Calvo, M.1
Fischer, A.2
-
21
-
-
0031570783
-
NADH oxidase activity from sera altered by capsaicin is widely distributed among cancer patients
-
Morre, DJ, Caldwell, S, Mayorga, A, Wu, LY and Morre, DM (1997). NADH oxidase activity from sera altered by capsaicin is widely distributed among cancer patients. Arch Biochem Biophys 342: 224-230.
-
(1997)
Arch Biochem Biophys
, vol.342
, pp. 224-230
-
-
Morre, D.J.1
Caldwell, S.2
Mayorga, A.3
Wu, L.Y.4
Morre, D.M.5
-
22
-
-
0037455919
-
Sera from cancer patients contain two oscillating ECTO-NOX activities with different period lengths
-
Wang, S, Morre, DM and Morre, DJ (2003). Sera from cancer patients contain two oscillating ECTO-NOX activities with different period lengths. Cancer Lett 190: 135-141.
-
(2003)
Cancer Lett
, vol.190
, pp. 135-141
-
-
Wang, S.1
Morre, D.M.2
Morre, D.J.3
-
23
-
-
30144444329
-
Long-term immune reconstitution in RAG-1-deficient mice treated by retroviral gene therapy: A balance between efficiency and toxicity
-
Lagresle-Peyrou, C, Yates, F, Malassis-Seris, M, Hue, C, Morillon, E, Garrigue, A et al. (2006). Long-term immune reconstitution in RAG-1-deficient mice treated by retroviral gene therapy: A balance between efficiency and toxicity. Blood 107: 63-72.
-
(2006)
Blood
, vol.107
, pp. 63-72
-
-
Lagresle-Peyrou, C.1
Yates, F.2
Malassis-Seris, M.3
Hue, C.4
Morillon, E.5
Garrigue, A.6
-
24
-
-
33750833078
-
Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer
-
Mostoslavsky, G, Fabian, AJ, Rooney, S, Alt, FW and Mulligan, RC (2006). Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer. Proc Natl Acad Sci USA 103: 16406-16411.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16406-16411
-
-
Mostoslavsky, G.1
Fabian, A.J.2
Rooney, S.3
Alt, F.W.4
Mulligan, R.C.5
-
25
-
-
33947210723
-
Importance of murine study design for testing toxicity of retroviral vectors in support of phase 1 trials
-
Will, E, Bailey, J, Schuesler, T, Modlich, U, Balcik, B, Burzynski, B et al. (2007). Importance of murine study design for testing toxicity of retroviral vectors in support of phase 1 trials. Mol Ther 15 782-791.
-
(2007)
Mol Ther
, vol.15
, pp. 782-791
-
-
Will, E.1
Bailey, J.2
Schuesler, T.3
Modlich, U.4
Balcik, B.5
Burzynski, B.6
-
26
-
-
33847636598
-
Murine leukemia following irradiation conditioning for transplantation of lentivirally-modified hematopoietic stem cells
-
Siapati, EK, Bigger, BW, Kashofer, K, Themis, M, Thrasher, AJ and Bonnet, D (2007). Murine leukemia following irradiation conditioning for transplantation of lentivirally-modified hematopoietic stem cells. Eur J Haematol 78: 303-313.
-
(2007)
Eur J Haematol
, vol.78
, pp. 303-313
-
-
Siapati, E.K.1
Bigger, B.W.2
Kashofer, K.3
Themis, M.4
Thrasher, A.J.5
Bonnet, D.6
-
27
-
-
1442306125
-
Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells
-
Rooney, S, Sekiguchi, J, Whitlow, S, Eckersdorff, M, Manis, JP, Lee, C et al. (2004). Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells. Proc Natl Acad Sci USA 101: 2410-2415.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2410-2415
-
-
Rooney, S.1
Sekiguchi, J.2
Whitlow, S.3
Eckersdorff, M.4
Manis, J.P.5
Lee, C.6
-
28
-
-
38649123723
-
Lentiviral gene-corrected CD34+ cells isolated from Artemis-deficient patients differentiate into functional B cells following injection into NOD-SCID mice
-
Lagresle-Peyrou, C, Benjelloun, F, Hue, C, Andre-Schmutz, I, Bonhomme, D, Malassis-Séris, M et al. (2007). Lentiviral gene-corrected CD34+ cells isolated from Artemis-deficient patients differentiate into functional B cells following injection into NOD-SCID mice. Mol Ther 16: 396-403.
-
(2007)
Mol Ther
, vol.16
, pp. 396-403
-
-
Lagresle-Peyrou, C.1
Benjelloun, F.2
Hue, C.3
Andre-Schmutz, I.4
Bonhomme, D.5
Malassis-Séris, M.6
-
29
-
-
0034646513
-
HIV-1 genome nuclear import is mediated by a central DNA flap
-
Zennou, V, Petit, C, Guetard, D, Nerhbass, U, Montagnier, L and Chameau, P (2000). HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 101: 173-185.
-
(2000)
Cell
, vol.101
, pp. 173-185
-
-
Zennou, V.1
Petit, C.2
Guetard, D.3
Nerhbass, U.4
Montagnier, L.5
Chameau, P.6
-
30
-
-
0027251463
-
The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments
-
Pannetier, C, Cochet, M, Darche, S, Casrouge, A, Zoller, M and Kourilsky, P (1993). The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments. Proc Natl Acad Sci USA 90: 4319-4323.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4319-4323
-
-
Pannetier, C.1
Cochet, M.2
Darche, S.3
Casrouge, A.4
Zoller, M.5
Kourilsky, P.6
-
31
-
-
20144389599
-
A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice
-
Charrier, S, Stockholm, D, Seye, K, Opolon, P, Taveau, M, Gross, DA et al. (2005). A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice. Gene Ther 12: 597-606.
-
(2005)
Gene Ther
, vol.12
, pp. 597-606
-
-
Charrier, S.1
Stockholm, D.2
Seye, K.3
Opolon, P.4
Taveau, M.5
Gross, D.A.6
-
32
-
-
0037108189
-
Polyclonal long-term repopulating stem cell clones in a primate model
-
Schmidt, M, Zickler, P, Hoffmann, G, Haas, S, Wissler, M, Muessig, A et al. (2002). Polyclonal long-term repopulating stem cell clones in a primate model. Blood 100: 2737-2743.
-
(2002)
Blood
, vol.100
, pp. 2737-2743
-
-
Schmidt, M.1
Zickler, P.2
Hoffmann, G.3
Haas, S.4
Wissler, M.5
Muessig, A.6
-
33
-
-
34548829881
-
Spectral karyotyping analysis of human and mouse chromosomes
-
Padilla-Nash, HM, Barenboim-Stapleton, L, Difilippantonio, MJ and Ried, T (2006). Spectral karyotyping analysis of human and mouse chromosomes. Nat Protoc 1: 3129-3142.
-
(2006)
Nat Protoc
, vol.1
, pp. 3129-3142
-
-
Padilla-Nash, H.M.1
Barenboim-Stapleton, L.2
Difilippantonio, M.J.3
Ried, T.4
|