Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow

Blood

Volumn 101, Issue 4, 2003, Pages 1446-1452

  Noordzij, Jeroen G ^b   Verkaik, Nicole S ^b   Van der Burg, Mirjam ^b   Van Veelen, Lieneke R ^b   De Bruin Versteeg, Sandra ^b   Wiegant, Wouter ^b   Vossen, Jaak M J J ^b   Weemaes, Corry M R ^b   De Groot, Ronald ^b   Zdzienicka, Malgorzata Z ^b   Van Gent, Dik C ^b   Van Dongen, Jacques J M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; GENE PRODUCT; PROTEIN ARTEMIS; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTEMIS GENE; ARTICLE; B LYMPHOCYTE; BONE MARROW EXAMINATION; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DISEASE CLASSIFICATION; DNA REPAIR; DNA STRAND BREAKAGE; FEMALE; FIBROBLAST; GENE ACTIVATION; GENE DELETION; GENE FUNCTION; GENE MUTATION; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOGENETICS; IONIZING RADIATION; MALE; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PHENOTYPE; PRE B LYMPHOCYTE; PRIORITY JOURNAL; RADIOSENSITIVITY; RAG GENE; RECOMBINANT GENE; SEQUENCE HOMOLOGY;

EID: 0037441592     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-01-0187     Document Type: Article

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