Agonist treatment did not affect association of mu opioid receptors with lipid rafts and cholesterol reduction had opposite effects on the receptor-mediated signaling in rat brain and CHO cells

Brain Research

Volumn 1184, Issue 1, 2007, Pages 46-56

  Huang, Peng ^a   Xu, Wei ^a   Yoon, Su In ^a   Chen, Chongguang ^a   Chong, Parkson Lee Gau ^a   Unterwald, Ellen M ^a   Liu Chen, Lee Yuan ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Brain; Cholesterol; Lipid rafts; Methyl cyclodextrin; Morphine; mu Opioid receptor

Indexed keywords

BUFFER; CHOLESTEROL; DELTA OPIATE RECEPTOR; DETERGENT; DIPRENORPHINE; ETORPHINE; GANGLIOSIDE GM1; GUANINE NUCLEOTIDE BINDING PROTEIN; METHYL BETA CYCLODEXTRIN; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST;

ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN NERVE CELL; CAUDATE NUCLEUS; CAVEOLA; CELL FRACTIONATION; CELL FREE SYSTEM; CELL MEMBRANE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; GENETIC TRANSFECTION; IN VIVO STUDY; LIPID RAFT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; SUCROSE DENSITY GRADIENT CENTRIFUGATION; THALAMUS NUCLEUS; WESTERN BLOTTING;

ANIMALS; BINDING, COMPETITIVE; BRAIN; CAVEOLIN 1; CHO CELLS; CHOLESTEROL; CRICETINAE; CRICETULUS; DIPRENORPHINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETORPHINE; MALE; MEMBRANE MICRODOMAINS; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION; TRANSFECTION;

RATTUS;

EID: 36348983962     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.09.096     Document Type: Article

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