Validation of the Medical Research Council and a newly developed prognostic index in patients with malignant glioma: How useful are prognostic indices in routine clinical practice?

Journal of Neuro-Oncology

Volumn 59, Issue 1, 2002, Pages 39-47

  Akman, Fadime ^a   Cooper, Rachel A ^a   Şen, Mehmet ^a   Tanriver, Yildiray ^a   Kentli, Süleyman ^a  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

High grade gliomas; Prognostic index; Survival

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN BIOPSY; CALCULATION; CANCER GRADING; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL PRACTICE; CLINICAL PROTOCOL; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE DURATION; EXCISION; FEMALE; GLIOBLASTOMA; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL DECISION MAKING; MEDICAL RESEARCH; MEDICAL SOCIETY; MULTIVARIATE ANALYSIS; PATIENT CODING; POSTOPERATIVE CARE; PROGNOSIS; SCORING SYSTEM; STATISTICAL ANALYSIS; SURVIVAL RATE; SURVIVAL TIME; VALIDATION PROCESS;

ADULT; AGED; AGED, 80 AND OVER; BIOPSY; BRAIN NEOPLASMS; COMBINED MODALITY THERAPY; FEMALE; GLIOMA; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; SURVIVAL RATE;

EID: 0036679237     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016353614525     Document Type: Article

References (35)

1. Combined modality therapy of operated astrocytomas grades III and IV. Confirmation of the value of post-operative irradiation and lack of potentiation of bleomycin on survival time
2. Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas: A cooperative clinical trial
3. Comparison of post-operative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas
4. A randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgery
5. Final report of phase I/II trial of hyperfractionated and accelerated hyperfractionated radiation therapy with carmustine for adults with supratentorial malignant gliomas. Radiation Therapy Oncology Group Study 83-02
6. Accelerated hyperfractionated radiotherapy for malignant gliomas
7. Modifying radical radiotherapy in high grade gliomas: Shortening the treatment time through acceleration
8. Misonidasole combined with hyperfractionation in the management of malignant glioma
9. Survival and quality of life after continuous accelerated radiotherapy of glioblastomas
10. Malignant astrocytoma. Hyperfractionated and standard radiotherapy with chemotherapy in a randomized prospective clinical trial
11. Superfractionation radiation therapy in the treatment of malignant astrocytoma
12. Randomized trial of three chemotherapy regimens and two radiotherapy regimens in postoperative treatment of malignant glioma. Brain Tumor Cooperative Group Trial 8001
13. Multi-drug versus single agent chemotherapy for high grade astrocytoma; Results of a meta-analysis
14. Phase I and pharmacokinetic study of preirradiation chemotherapy with BCNU, cisplatin, etoposide, and accelerated radiation therapy in patients with high-grade glioma
15. A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme
16. Randomized trial of procarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma. A Medical Research Council Trial
17. Prognostic factors for high-grade malignant glioma: Development of a prognostic index
18. Application of the MRC brain tumour prognostic index to patients with malignant glioma not managed in randomised control trial
19. Supratentorial anaplastic gliomas in adults: The prognostic importance of extent of resection and prior low-grade glioma
20. Radiation therapy with uneven fractionation for malignant gliomas
21. Accelerated radiotherapy with concomitant ACNU/Ara-C for the treatment of malignant glioma
22. The new WHO classification of brain tumors
23. Influence of location and extent of surgical resection on survival of patients with glioblastoma multiforme: Results of three consecutive Radiation Therapy Oncology Group (RTOG) clinical trials
24. Clinicopathologic study of 85 similarly treated patients with anaplastic astrocytic tumors. An analysis of DNA content (ploidy), cellular proliferation, and p53 expression
25. Selection of eligible patients with supratentorial glioblastoma multiforme for gross total resection
26. Does extent of surgery influence outcome for astrocytoma with atypical or anaplastic foci (AAF)? A report from three Radiation Therapy Oncology Group (RTOG) trials
27. Highly anaplastic astrocytoma: A review of 357 patients treated between 1977 and 1989
28. Radiation therapy and bromodeoxyuridine chemotherapy followed by procarbazine, lomustine, and vincristine for the treatment of anaplastic gliomas
29. Radiosurgery in the initial management of malignant gliomas: Survival comparison with the RTOG recursive partitioning analysis
30. Long-term survival in malignant glioma. Prognostic factors
31. Prognostic factors in high-grade malignant glioma. A multivariate analysis of 76 cases with postoperative radiotherapy
32. Potential pitfalls in the use of p-values and in interpretation on significance levels
33. A study of the effect of misonidazole in conjunction with radiotherapy for the treatment of grades 3 and 4 astrocytoma
34. A Medical Research Council trial of two radiotherapy doses in the treatment of grades 3 and 4 astrocytoma. The Medical Research Council Brain Tumour Working Party
35. Supratentorial malignant glioma: An analysis of radiation therapy in 178 cases