Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development

BMC Biology

Volumn 5, Issue , 2007, Pages

  Schwab, Kristopher R ^a   Patterson, Larry T ^a   Hartman, Heather A ^a   Song, Ni ^a   Lang, Richard A ^a   Lin, Xinhua ^a   Potter, S Steven ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CHEMOKINE; CXCL13 CHEMOKINE; KALLIKREIN; KALLIKREIN 5; NUCLEAR PROTEIN; PYGOPUS 1 PROTEIN; PYGOPUS 2 PROTEIN; RENIN; RENIN 2; SODIUM GLUCOSE COTRANSPORTER 2; TIMELESS PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WNT PROTEIN; PYGOPUS 2 PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; CLEFT PALATE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMBRYO; EVOLUTION; EXENCEPHALY; GENE EXPRESSION; GENE MUTATION; GROWTH RETARDATION; HOMOZYGOSITY; IN SITU HYBRIDIZATION; KIDNEY DEVELOPMENT; LENS DISEASE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STROMA CELL; ANIMAL; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; KIDNEY; MOUSE MUTANT; MUTATION; PRENATAL DEVELOPMENT; REPORTER GENE; URETER;

ARMADILLO; MAMMALIA; PYGOPUS;

ANIMALS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; MICE; MICE, MUTANT STRAINS; MICROSCOPY, CONFOCAL; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; URETER; WNT PROTEINS;

EID: 34247892478     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-5-15     Document Type: Article

References (39)

1. Saxen L Sariola H Early organogenesis of the kidney Pediatr Nephrol 1987 1 385-392 10.1007/BF00849241 3153305
2. Carroll TJ Park JS Hayashi S Majumdar A McMahon AP Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system Dev Cell 2005 9 283-292 10.1016/j.devcel.2005.05.016 16054034
3. Stark K Vainio S Vassileva G McMahon AP Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4 Nature 1994 372 679-683 10.1038/372679a0 7990960
4. Majumdar A Vainio S Kispert A McMahon J McMahon AP Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development Development 2003 130 3175-3185 10.1242/dev.00520 12783789
5. Du SJ Purcell SM Christian JL McGrew LL Moon RT Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos Mol Cell Biol 1995 15 2625-2634 230492 7739543
6. Maurus D Heligon C Burger-Schwarzler A Brandli AW Kuhl M Noncanonical Wnt-4 signaling and EAF2 are required for eye development in Xenopus laevis Embo J 2005 24 1181-1191 556406 15775981 10.1038/sj.emboj.7600603
7. Pandur P Lasche M Eisenberg LM Kuhl M Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis Nature 2002 418 636-641 10.1038/nature00921 12167861
8. Belenkaya TY Han C Standley HJ Lin X Houston DW Heasman J Lin X pygopus Encodes a nuclear protein essential for wingless/Wnt signaling Development 2002 129 4089-4101 12163411
9. Kramps T Peter O Brunner E Nellen D Froesch B Chatterjee S Murone M Zullig S Basler K Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex Cell 2002 109 47-60 10.1016/S0092-8674(02)00679-7 11955446
10. Parker DS Jemison J Cadigan KM Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila Development 2002 129 2565-2576 12015286
11. Thompson B Townsley F Rosin-Arbesfeld R Musisi H Bienz M A new nuclear component of the Wnt signalling pathway Nat Cell Biol 2002 4 367-373 10.1038/ncb786 11988739
12. Townsley FM Cliffe A Bienz M Pygopus and Legless target Armadillo/ beta-catenin to the nucleus to enable its transcriptional co-activator function Nat Cell Biol 2004 6 626-633 10.1038/ncb1141 15208637
13. Stadeli R Basler K Dissecting nuclear Wingless signalling: Recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins Mech Dev 2005 122 1171-1182 10.1016/j.mod.2005.07.004 16169192
14. Li B Mackay DR Ma J Dai X Cloning and developmental expression of mouse pygopus 2, a putative Wnt signaling component Genomics 2004 84 398-405 10.1016/j.ygeno.2004.04.007 15234002
15. Schwenk F Baron U Rajewsky K A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells Nucleic Acids Res 1995 23 5080-5081 307516 8559668 10.1093/ nar/23.24.5080
16. Gray PA Fu H Luo P Zhao Q Yu J Ferrari A Tenzen T Yuk DI Tsung EF Cai Z Mouse brain organization revealed through direct genome-scale TF expression analysis Science 2004 306 2255-2257 10.1126/science.1104935 15618518
17. Pritchard-Jones K Fleming S Davidson D Bickmore W Porteous D Gosden C Bard J Buckler A Pelletier J Housman D The candidate Wilms' tumour gene is involved in genitourinary development Nature 1990 346 194-197 10.1038/ 346194a0 2164159
18. Vestweber D Kemler R Ekblom P Cell-adhesion molecule uvomorulin during kidney development Dev Biol 1985 112 213-221 10.1016/ 0012-1606(85)90135-6 3902535
19. Fan QW Kadomatsu K Uchimura K Muramatsu T Embigin/basigin subgroup of the immunoglobulin superfamily: Different modes of expression during mouse embryogenesis and correlated expression with carbohydrate antigenic markers Dev Growth Differ 1998 40 277-286 10.1046/ j.1440-169X.1998.t01-1-00003.x 9639355
20. Kispert A Vainio S Shen L Rowitch DH McMahon AP Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips Development 1996 122 3627-3637 8951078
21. Maretto S Cordenonsi M Dupont S Braghetta P Broccoli V Hassan AB Volpin D Bressan GM Piccolo S Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors Proc Natl Acad Sci USA 2003 100 3299-3304 152286 12626757 10.1073/pnas.0434590100
22. Davies JA Garrod DR Induction of early stages of kidney tubule differentiation by lithium ions Dev Biol 1995 167 50-60 10.1006/ dbio.1995.1006 7851662
23. van den Heuvel LP Assink K Willemsen M Monnens L Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2) Hum Genet 2002 111 544-547 10.1007/ s00439-002-0820-5 12436245
24. van Montfoort JE Schmid TE Adler ID Meier PJ Hagenbuch B Functional characterization of the mouse organic-anion-transporting polypeptide 2 Biochim Biophys Acta 2002 1564 183-188 10.1016/S0005-2736(02)00445-5 12101011
25. Borgono CA Michael IP Diamandis EP Human tissue kallikreins: Physiologic roles and applications in cancer Mol Cancer Res 2004 2 257-280 15192120
26. Cheng ZJ Tikkanen I Vapaatalo H Mervaala EM Vascular effects of COX inhibition and AT1 receptor blockade in transgenic rats harboring mouse renin-2 gene J Physiol Pharmacol 2002 53 597-613 12512695
27. Niimura F Kon V Ichikawa I The renin-angiotensin system in the development of the congenital anomalies of the kidney and urinary tract Curr Opin Pediatr 2006 18 161-166 10.1097/01.mop.0000193288.56528.40 16601496
28. Li Z Stuart RO Qiao J Pavlova A Bush KT Pohl M Sakurai H Nigam SK A role for Timeless in epithelial morphogenesis during kidney development Proc Natl Acad Sci USA 2000 97 10038-10043 27664 10963667 10.1073/ pnas.97.18.10038
29. Shtutman M Zhurinsky J Simcha I Albanese C D'Amico M Pestell R Ben-Ze'ev A The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway Proc Natl Acad Sci USA 1999 96 5522-5527 21892 10318916 10.1073/ pnas.96.10.5522
30. Xu L Corcoran RB Welsh JW Pennica D Levine AJ WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene Genes Dev 2000 14 585-595 316421 10716946
31. Tao Q Yokota C Puck H Kofron M Birsoy B Yan D Asashima M Wylie CC Lin X Heasman J Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos Cell 2005 120 857-871 10.1016/j.cell.2005.01.013 15797385
32. Mosimann C Hausmann G Basler K Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/ Armadillo Cell 2006 125 327-341 10.1016/j.cell.2006.01.053 16630820
33. Krieghoff E Behrens J Mayr B Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention J Cell Sci 2006 119 1453-1463 10.1242/jcs.02864 16554443
34. Bell SM Schreiner CM Waclaw RR Campbell K Potter SS Scott WJ Sp8 is crucial for limb outgrowth and neuropore closure Proc Natl Acad Sci USA 2003 100 12195-12200 218735 14526104 10.1073/pnas.2134310100
35. Patterson LT Pembaur M Potter SS Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney Development 2001 128 2153-2161 11493536
36. Schwab K Hartman HA Liang HC Aronow BJ Patterson LT Potter SS Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development Dev Biol 2006 293 540-554 10.1016/j.ydbio.2006.02.023 16581055
37. Rozen S Skaletsky H Primer3 on the WWW for general users and for biologist programmers Methods Mol Biol 2000 132 365-386 10547847
38. Livak KJ Schmittgen TD Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 2001 25 402-408 10.1006/meth.2001.1262 11846609
39. List of target genes of Wnt/b-catenin signaling http://www.stanford.edu/~rnusse/pathways/targets.html