메뉴 건너뛰기




Volumn 26, Issue 7, 2008, Pages 718-724

The effect of dalteparin, a kind of low molecular weight heparin, on lung adenocarcinoma A549 cell line in vitro

Author keywords

Dalteparin; Low molecular weight heparin; Lung adenocarcinoma; p21WAF1; p27 KIP1

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DALTEPARIN; LOW MOLECULAR WEIGHT HEPARIN;

EID: 48249094625     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900801935631     Document Type: Article
Times cited : (17)

References (45)
  • 1
    • 20244376337 scopus 로고    scopus 로고
    • The effect of low molecular weight heparin on survival in patients with advanced malignancy
    • Klerk, C.P.; Smorenburg, S.M.; Otten, H.M.; et al. The effect of low molecular weight heparin on survival in patients with advanced malignancy. J Clin Oncol 2005, 23, 2130-2135.
    • (2005) J Clin Oncol , vol.23 , pp. 2130-2135
    • Klerk, C.P.1    Smorenburg, S.M.2    Otten, H.M.3
  • 2
    • 3042704507 scopus 로고    scopus 로고
    • Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: The fragmin advanced malignancy outcome study (FAMOUS)
    • Kakkar, A.K.; Levine, M.N.; Kadziola, Z.; et al. Low molecular weight heparin, therapy with dalteparin, and survival in advanced cancer: the fragmin advanced malignancy outcome study (FAMOUS). J Clin Oncol 2004, 22, 1944-1948.
    • (2004) J Clin Oncol , vol.22 , pp. 1944-1948
    • Kakkar, A.K.1    Levine, M.N.2    Kadziola, Z.3
  • 3
    • 12844289104 scopus 로고    scopus 로고
    • A randomized clinical trial of combination chemotherapy with and without low-molecular-weight heparin in small cell lung cancer
    • Altinbas, M.; Coskun, H.S.; Er, O.; et al. A randomized clinical trial of combination chemotherapy with and without low-molecular-weight heparin in small cell lung cancer. J Thromb Haemost 2004, 2(8), 1266-1271.
    • (2004) J Thromb Haemost , vol.2 , Issue.8 , pp. 1266-1271
    • Altinbas, M.1    Coskun, H.S.2    Er, O.3
  • 4
    • 34248202262 scopus 로고    scopus 로고
    • Low molecular weight heparin (LMWH) increases the efficacy of cisplatinum plus gemcitabine combination in advanced pancreatic cancer
    • Icli, F.; Akbulut, H.; Utkan, G.; et al. Low molecular weight heparin (LMWH) increases the efficacy of cisplatinum plus gemcitabine combination in advanced pancreatic cancer. J Surg Oncol 2007, 95(6), 507-512.
    • (2007) J Surg Oncol , vol.95 , Issue.6 , pp. 507-512
    • Icli, F.1    Akbulut, H.2    Utkan, G.3
  • 5
    • 0017576983 scopus 로고
    • Suppression by heparin of smooth muscle cell proliferation in injured arteries
    • Clowes, A.W.; Karnovsky, M.J. Suppression by heparin of smooth muscle cell proliferation in injured arteries. Nature 1977, 265(5595), 625-626.
    • (1977) Nature , vol.265 , Issue.5595 , pp. 625-626
    • Clowes, A.W.1    Karnovsky, M.J.2
  • 6
    • 0018873310 scopus 로고
    • Inhibition of rat arterial smooth muscle cell proliferation by heparin. In vivo studies with anticoagulant and nonanticoagulant heparin
    • Guyton, J.R.; Rosenberg, R.D.; Clowes, A.W.; et al. Inhibition of rat arterial smooth muscle cell proliferation by heparin. In vivo studies with anticoagulant and nonanticoagulant heparin. Circ Res 1980, 46(5), 625-634.
    • (1980) Circ Res , vol.46 , Issue.5 , pp. 625-634
    • Guyton, J.R.1    Rosenberg, R.D.2    Clowes, A.W.3
  • 7
    • 0032926525 scopus 로고    scopus 로고
    • Heparin inhibits proliferation of myometrial and leiomyomal smooth muscle cells through the induction of alpha-smooth muscle actin, calponin h1 and p27
    • Horiuchi, A.; Nikaido, T.; Ya-Li, Z.; et al. Heparin inhibits proliferation of myometrial and leiomyomal smooth muscle cells through the induction of alpha-smooth muscle actin, calponin h1 and p27. Mol Hum Reprod 1999, 5(2), 139-145.
    • (1999) Mol Hum Reprod , vol.5 , Issue.2 , pp. 139-145
    • Horiuchi, A.1    Nikaido, T.2    Ya-Li, Z.3
  • 8
    • 0022181969 scopus 로고
    • Heparin inhibits mesangial cell proliferation in habu-venom-induced glomerular injury
    • Coffey, A.K.; Karnovsky M.J. Heparin inhibits mesangial cell proliferation in habu-venom-induced glomerular injury. Am J Pathol 1985, 120(2), 248-255.
    • (1985) Am J Pathol , vol.120 , Issue.2 , pp. 248-255
    • Coffey, A.K.1    Karnovsky, M.J.2
  • 9
    • 0028788010 scopus 로고
    • Heparin and PGE2 inhibit DNA synthesis in human airway smooth muscle cells in culture
    • Johnson, P.R.; Armour, C.L.; Carey, D.; et al. Heparin and PGE2 inhibit DNA synthesis in human airway smooth muscle cells in culture. Am J Physiol 1995, 269(4 Pt 1), L514-519
    • (1995) Am J Physiol , vol.269 , Issue.4 PART 1
    • Johnson, P.R.1    Armour, C.L.2    Carey, D.3
  • 10
    • 0033022310 scopus 로고    scopus 로고
    • Apoptotic effects of heparin on lymphoblasts, neutrophils, and mononuclear cells: Results of a preliminary in vitro study
    • Erduran, E.; Tekelioǧlu, Y.; Gedik, Y.; et al. Apoptotic effects of heparin on lymphoblasts, neutrophils, and mononuclear cells: results of a preliminary in vitro study. Am J Hemato 1999, 61(2), 90-93.
    • (1999) Am J Hemato , vol.61 , Issue.2 , pp. 90-93
    • Erduran, E.1    Tekelioǧlu, Y.2    Gedik, Y.3
  • 11
    • 0037441895 scopus 로고    scopus 로고
    • Cell cycle deregulation in B-cell lymphomas
    • Margarita, S.B.; Abel, S.A.; Miguel, A.P. Cell cycle deregulation in B-cell lymphomas. Blood 2003, 101(4), 1220-1235.
    • (2003) Blood , vol.101 , Issue.4 , pp. 1220-1235
    • Margarita, S.B.1    Abel, S.A.2    Miguel, A.P.3
  • 12
    • 0028959979 scopus 로고
    • Mammalian antiproliferative signals and their targets
    • Massaque, J.; Polyak, K. Mammalian antiproliferative signals and their targets. Curr Opin Genet Dev 1995, 5(1), 91-96.
    • (1995) Curr Opin Genet Dev , vol.5 , Issue.1 , pp. 91-96
    • Massaque, J.1    Polyak, K.2
  • 13
    • 0034092911 scopus 로고    scopus 로고
    • Regulation of the Cdk inhibitor p27 and its deregulation in cancer
    • Slingerland, J.; Pagano, M. Regulation of the Cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol 2000, 183(1), 10-17.
    • (2000) J Cell Physiol , vol.183 , Issue.1 , pp. 10-17
    • Slingerland, J.1    Pagano, M.2
  • 14
    • 0037112178 scopus 로고    scopus 로고
    • Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence
    • Zou, X.; Ray, D.; Aziyu, A.; et al. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes Dev 2002, 16(22), 2923-2934.
    • (2002) Genes Dev , vol.16 , Issue.22 , pp. 2923-2934
    • Zou, X.1    Ray, D.2    Aziyu, A.3
  • 15
    • 27644564685 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p27Kip1, but not p21WAF1/Cip1, is required for inhibition of hypoxia-induced pulmonary hypertension and remodeling by heparin in mice
    • Yu, L.; Quinn, D.A.; Garg, H.G.; et al. Cyclin-dependent kinase inhibitor p27Kip1, but not p21WAF1/Cip1, is required for inhibition of hypoxia-induced pulmonary hypertension and remodeling by heparin in mice. Circ Res 2005, 97(9), 937-945.
    • (2005) Circ Res , vol.97 , Issue.9 , pp. 937-945
    • Yu, L.1    Quinn, D.A.2    Garg, H.G.3
  • 16
    • 0034326271 scopus 로고    scopus 로고
    • Unfractionated and low molecular weight heparin affect fibrin structure and angiogenesis in vitro
    • Collen, A.; Smorenburg, S.M.; Peters, E.; et al. Unfractionated and low molecular weight heparin affect fibrin structure and angiogenesis in vitro. Cancer Res 2000, 60(21), 6196-6200.
    • (2000) Cancer Res , vol.60 , Issue.21 , pp. 6196-6200
    • Collen, A.1    Smorenburg, S.M.2    Peters, E.3
  • 17
    • 48249090198 scopus 로고    scopus 로고
    • Nasir, F.A.; Patel, H.K.; Scully M.F. The low molecular weight heparin dalteparin sodium inhibits angiogenesis and induces apoptosis in an experimental tumor model. Blood 2003, 102(3), Abstract.
    • Nasir, F.A.; Patel, H.K.; Scully M.F. The low molecular weight heparin dalteparin sodium inhibits angiogenesis and induces apoptosis in an experimental tumor model. Blood 2003, 102(3), Abstract.
  • 18
    • 0035853111 scopus 로고    scopus 로고
    • Heparin and cancer revisited: Mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis
    • Borsig, L.; Wong, R.; Feramisco, J.; et al. Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis. Proc Natl Acad Sci USA 2001, 98(6), 3352-3357
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.6 , pp. 3352-3357
    • Borsig, L.1    Wong, R.2    Feramisco, J.3
  • 19
    • 16544390675 scopus 로고    scopus 로고
    • Endothelial P-selectin as a target of heparin action in experimental melanoma lung metastasis
    • Ludwig, R.J.; Boehme, B.; Podda, M.; et al. Endothelial P-selectin as a target of heparin action in experimental melanoma lung metastasis. Cancer Res 2004, 64(8), 2743-2750.
    • (2004) Cancer Res , vol.64 , Issue.8 , pp. 2743-2750
    • Ludwig, R.J.1    Boehme, B.2    Podda, M.3
  • 20
    • 0032519957 scopus 로고    scopus 로고
    • Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents
    • Koenig, A.; Norgard-Sumnicht, K.; Linhardt, R.; et al. Differential interactions of heparin and heparan sulfate glycosaminoglycans with the selectins. Implications for the use of unfractionated and low molecular weight heparins as therapeutic agents. J Clin Invest 1998, 101(4), 877-889.
    • (1998) J Clin Invest , vol.101 , Issue.4 , pp. 877-889
    • Koenig, A.1    Norgard-Sumnicht, K.2    Linhardt, R.3
  • 21
    • 0036086066 scopus 로고    scopus 로고
    • Low-molecular-weight heparins inhibit CCL21-induced T cell adhesion and migration
    • Christopherson, K.W.; Campbell, J.J.; Travers, J.B.; et al. Low-molecular-weight heparins inhibit CCL21-induced T cell adhesion and migration. J Pharmacol Exp Ther 2002, 302(1), 290-295.
    • (2002) J Pharmacol Exp Ther , vol.302 , Issue.1 , pp. 290-295
    • Christopherson, K.W.1    Campbell, J.J.2    Travers, J.B.3
  • 22
    • 0035109328 scopus 로고    scopus 로고
    • The complex effects of heparins on cancer progression and metastasis in experimental studies
    • Smorenburg, S.M.; Van, N.C.J.F. The complex effects of heparins on cancer progression and metastasis in experimental studies. Pharmacol Rev 2001, 53(1), 93-105.
    • (2001) Pharmacol Rev , vol.53 , Issue.1 , pp. 93-105
    • Smorenburg, S.M.1    Van, N.C.J.F.2
  • 23
    • 2442545704 scopus 로고    scopus 로고
    • Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells
    • Ishii, T.; Fujishiro, M.; Masudav M.; et al. Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells. Eur Respir J 2004, 23(5), 665-670.
    • (2004) Eur Respir J , vol.23 , Issue.5 , pp. 665-670
    • Ishii, T.1    Fujishiro, M.2    Masudav, M.3
  • 24
    • 0029980043 scopus 로고    scopus 로고
    • Gottlieb, T.M.; Oren, M. p53 in growth control and neoplasia. Biochim Biophys Acta 1996, 1287(2-3), 77-l02.
    • Gottlieb, T.M.; Oren, M. p53 in growth control and neoplasia. Biochim Biophys Acta 1996, 1287(2-3), 77-l02.
  • 25
    • 0026652346 scopus 로고
    • A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F
    • Helin, K.; Lees, J.A.; Vidal, M.; et al. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell 1992, 70(2), 337-350.
    • (1992) Cell , vol.70 , Issue.2 , pp. 337-350
    • Helin, K.1    Lees, J.A.2    Vidal, M.3
  • 26
    • 0032484989 scopus 로고    scopus 로고
    • Retinoblastoma protein recruits histone deacetylase to repress transcription
    • Brehm, A.; Miska, E.A.; McCance, D.J.; et al. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature (Lond) 1998, 391(6667), 597-601.
    • (1998) Nature (Lond) , vol.391 , Issue.6667 , pp. 597-601
    • Brehm, A.1    Miska, E.A.2    McCance, D.J.3
  • 27
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr, C.J.; Roberts, J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999, 13(12), 1501-1512.
    • (1999) Genes Dev , vol.13 , Issue.12 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 28
    • 0029144632 scopus 로고
    • Unfractionated heparin and low molecular weight heparin do not inhibit the growth of proliferating human arterial smooth muscle cells in culture
    • Stavenow, L.; Lindblad, B.; Xu, C.B.; Unfractionated heparin and low molecular weight heparin do not inhibit the growth of proliferating human arterial smooth muscle cells in culture. Eur J Vasc Endovasc Surg 1995, 10(2), 215-219.
    • (1995) Eur J Vasc Endovasc Surg , vol.10 , Issue.2 , pp. 215-219
    • Stavenow, L.1    Lindblad, B.2    Xu, C.B.3
  • 29
    • 0025142604 scopus 로고
    • Inhibition of BC3H-1 cell growth by heparin is related to decreased mitogenic signaling
    • Vannucchi, S.; Pasquali, F.; Chiarugi, V.P.; et al. Inhibition of BC3H-1 cell growth by heparin is related to decreased mitogenic signaling. Biochem Biophys Res Commun 1990, 170(1), 89-95.
    • (1990) Biochem Biophys Res Commun , vol.170 , Issue.1 , pp. 89-95
    • Vannucchi, S.1    Pasquali, F.2    Chiarugi, V.P.3
  • 30
    • 33947098035 scopus 로고    scopus 로고
    • Antiangiogenic and apoptotic properties of a novel amphiphilic folate-heparin-lithocholate derivative having cellular internality for cancer therapy
    • Yu, M.K.; Lee, D.Y.; Kim, Y.S.; et al. Antiangiogenic and apoptotic properties of a novel amphiphilic folate-heparin-lithocholate derivative having cellular internality for cancer therapy. Pharm Res 2007, 24(4), 705-714.
    • (2007) Pharm Res , vol.24 , Issue.4 , pp. 705-714
    • Yu, M.K.1    Lee, D.Y.2    Kim, Y.S.3
  • 31
    • 0034624331 scopus 로고    scopus 로고
    • The p21 (cip1/waf1) cyclin-dependent kinase inhibitor enhances the cytotoxic effect of cisplatin in human ovarian carcinoma cells
    • Lincet, H.; Poulain, L.; Remy, J.S.; et al. The p21 (cip1/waf1) cyclin-dependent kinase inhibitor enhances the cytotoxic effect of cisplatin in human ovarian carcinoma cells. Cancer Lett 2000, 161(1), 17-26.
    • (2000) Cancer Lett , vol.161 , Issue.1 , pp. 17-26
    • Lincet, H.1    Poulain, L.2    Remy, J.S.3
  • 32
    • 0035128134 scopus 로고    scopus 로고
    • Suppression of mammary carcinoma growth in vitro and in vivo by inducible expression of the Cdk inhibitor p21
    • Shibata, M.A.; Yoshidome, K.; Shibata, E.; et al. Suppression of mammary carcinoma growth in vitro and in vivo by inducible expression of the Cdk inhibitor p21. Cancer Gene Ther 2001, 8(1), 23-35.
    • (2001) Cancer Gene Ther , vol.8 , Issue.1 , pp. 23-35
    • Shibata, M.A.1    Yoshidome, K.2    Shibata, E.3
  • 33
    • 0033577936 scopus 로고    scopus 로고
    • Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells
    • Fotedar, R.; Brickner, H.; Saadatmandi, N.; et al. Effect of p21waf1/cip1 transgene on radiation induced apoptosis in T cells. Oncogene 1999, 18(24), 3652-3658.
    • (1999) Oncogene , vol.18 , Issue.24 , pp. 3652-3658
    • Fotedar, R.1    Brickner, H.2    Saadatmandi, N.3
  • 34
    • 0036024544 scopus 로고    scopus 로고
    • Overexpression of p27(Kip1) induces growth arrest and apoptosis in an oral cancer cell line
    • Supriatno; Harada, K.; Hoque, M.O.; et al. Overexpression of p27(Kip1) induces growth arrest and apoptosis in an oral cancer cell line. Oral Oncol 2002, 38(7), 730-736.
    • (2002) Oral Oncol , vol.38 , Issue.7 , pp. 730-736
    • Supriatno1    Harada, K.2    Hoque, M.O.3
  • 35
    • 0031439355 scopus 로고    scopus 로고
    • Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27
    • Katayose, Y.; Kim, M.; Rakkar, A.N.; et al. Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res 1997, 57(24), 5441-5445.
    • (1997) Cancer Res , vol.57 , Issue.24 , pp. 5441-5445
    • Katayose, Y.1    Kim, M.2    Rakkar, A.N.3
  • 36
    • 1942445228 scopus 로고    scopus 로고
    • Poly(beta-amino ester)s promote cellular uptake of heparin and cancer cell death
    • Berry, D.; Lynn, D.M.; Sasisekharan, R.; et al. Poly(beta-amino ester)s promote cellular uptake of heparin and cancer cell death. Chem Biol 2004, 11(4), 487-498.
    • (2004) Chem Biol , vol.11 , Issue.4 , pp. 487-498
    • Berry, D.1    Lynn, D.M.2    Sasisekharan, R.3
  • 37
    • 36249012577 scopus 로고    scopus 로고
    • In vitro investigation of the apoptotic effect of heparin on lymphoblasts by using flow cytometric DNA analysis and fluorometric caspase-3 and -8 activities
    • Erduran, E.; Deger, O.; Albayrak, D.; et al. In vitro investigation of the apoptotic effect of heparin on lymphoblasts by using flow cytometric DNA analysis and fluorometric caspase-3 and -8 activities. DNA Cell Biol 2007, 26(11), 803-808.
    • (2007) DNA Cell Biol , vol.26 , Issue.11 , pp. 803-808
    • Erduran, E.1    Deger, O.2    Albayrak, D.3
  • 38
    • 3042804046 scopus 로고    scopus 로고
    • In vitro determination of the apoptotic effect of heparin on lymphoblasts using DNA analysis and measurements of Fas and Bcl-2 proteins by flow cytometry
    • Erduran, E.; Tekelioglu, Y.; Gedik, Y.; et al. In vitro determination of the apoptotic effect of heparin on lymphoblasts using DNA analysis and measurements of Fas and Bcl-2 proteins by flow cytometry. Pediatr Hematol Oncol 2004, 21(5), 383-391.
    • (2004) Pediatr Hematol Oncol , vol.21 , Issue.5 , pp. 383-391
    • Erduran, E.1    Tekelioglu, Y.2    Gedik, Y.3
  • 39
    • 0033080402 scopus 로고    scopus 로고
    • Transcriptional regulation of the p21(WAF1/CIP1) gene
    • Gartel, A.L.; Tyner, A.L. Transcriptional regulation of the p21(WAF1/CIP1) gene. Exp Cell Res 1999, 246(2), 280-289.
    • (1999) Exp Cell Res , vol.246 , Issue.2 , pp. 280-289
    • Gartel, A.L.1    Tyner, A.L.2
  • 40
    • 0033623850 scopus 로고    scopus 로고
    • Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination
    • Sheaff, R.J.; Singer, J.D.; Swanger, J.; et al. Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination. Mol Cell 2000, 5(2), 403-410.
    • (2000) Mol Cell , vol.5 , Issue.2 , pp. 403-410
    • Sheaff, R.J.1    Singer, J.D.2    Swanger, J.3
  • 41
    • 0035872863 scopus 로고    scopus 로고
    • A degradation signal located in the C-terminus of p21WAF1/ CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome
    • Touitou, R.; Richardson, J.; Bose, S.; et al. A degradation signal located in the C-terminus of p21WAF1/ CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome. Embo J 2001, 20(10), 2367-2375.
    • (2001) Embo J , vol.20 , Issue.10 , pp. 2367-2375
    • Touitou, R.1    Richardson, J.2    Bose, S.3
  • 42
    • 0031015044 scopus 로고    scopus 로고
    • Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation
    • Maki, C.G.; Howley, P.M. Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol Cell Biol 1997, 17(1), 355-363.
    • (1997) Mol Cell Biol , vol.17 , Issue.1 , pp. 355-363
    • Maki, C.G.1    Howley, P.M.2
  • 43
    • 0033176887 scopus 로고    scopus 로고
    • SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
    • Carrano, A.C.; Eytan, E.; Hershko, A.; et al. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nature Cell Biol 1999, 1(4), 193-199.
    • (1999) Nature Cell Biol , vol.1 , Issue.4 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3
  • 44
    • 11144352753 scopus 로고    scopus 로고
    • Generic low-molecular-weight heparins: Some practical considerations
    • Fareed, J.; Leong, W.L.; Hoppensteadt, D.A.; et al. Generic low-molecular-weight heparins: some practical considerations. Semin Thromb Hemost 2004, 30(6), 703-713.
    • (2004) Semin Thromb Hemost , vol.30 , Issue.6 , pp. 703-713
    • Fareed, J.1    Leong, W.L.2    Hoppensteadt, D.A.3
  • 45
    • 0142200006 scopus 로고    scopus 로고
    • The cytoprotective role of a low-molecular-weight heparin fragment studied in an experimental model of glomerulotoxicity
    • Deepa, P.R.; Varalakshmi, P. The cytoprotective role of a low-molecular-weight heparin fragment studied in an experimental model of glomerulotoxicity. Eur J Pharmacol 2003, 478(2-3), 199-205.
    • (2003) Eur J Pharmacol , vol.478 , Issue.2-3 , pp. 199-205
    • Deepa, P.R.1    Varalakshmi, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.