메뉴 건너뛰기




Volumn 23, Issue 5, 2004, Pages 665-670

Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells

Author keywords

Apoptosis; Cell cycle; Intracellular localisation; p27Kipl; Phosphorylation

Indexed keywords

COMPLEMENTARY DNA; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1B; SERINE; SMALL INTERFERING RNA; THREONINE; UNCLASSIFIED DRUG;

EID: 2442545704     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.04.00096204     Document Type: Article
Times cited : (17)

References (27)
  • 1
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999; 13: 1501-1512.
    • (1999) Genes Dev. , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 2
    • 0034092911 scopus 로고    scopus 로고
    • Regulation of the Cdk inhibitor p27 and its deregulation in cancer
    • Slingerland J, Pagano M. Regulation of the Cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol 2000; 183: 10-17.
    • (2000) J. Cell. Physiol. , vol.183 , pp. 10-17
    • Slingerland, J.1    Pagano, M.2
  • 3
    • 14444268041 scopus 로고    scopus 로고
    • Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
    • Esposito V, Baldi A, De Luca A, et al. Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res 1997; 57: 3381-3385.
    • (1997) Cancer Res. , vol.57 , pp. 3381-3385
    • Esposito, V.1    Baldi, A.2    De Luca, A.3
  • 4
    • 0035881618 scopus 로고    scopus 로고
    • An adenovirus expressing mutant p27 showed more potent antitumor effects than adenovirus-p27 wild type
    • Park KH, Seol Y, Kim TY, et al. An adenovirus expressing mutant p27 showed more potent antitumor effects than adenovirus-p27 wild type. Cancer Res 2001; 61: 6163-6169.
    • (2001) Cancer Res. , vol.61 , pp. 6163-6169
    • Park, K.H.1    Seol, Y.2    Kim, T.Y.3
  • 5
    • 0031283291 scopus 로고    scopus 로고
    • p27Kip1 overexpression causes apoptotic death of mammalian cells
    • Wang X, Gorospe M, Huang Y, Holbrook N. p27Kip1 overexpression causes apoptotic death of mammalian cells. Oncogene 1997; 15: 2991-2997.
    • (1997) Oncogene , vol.15 , pp. 2991-2997
    • Wang, X.1    Gorospe, M.2    Huang, Y.3    Holbrook, N.4
  • 6
    • 0033522231 scopus 로고    scopus 로고
    • Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1, and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity
    • Schreiber M, Muller WJ, Singh G, Graham FL. Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21WAF1/CIP1, and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity. Oncogene 1999; 18: 1663-1676.
    • (1999) Oncogene , vol.18 , pp. 1663-1676
    • Schreiber, M.1    Muller, W.J.2    Singh, G.3    Graham, F.L.4
  • 8
    • 0035144958 scopus 로고    scopus 로고
    • Protective function of p27 (KIP1) against apoptosis in small cell lung cancer cells in unfavorable microenvironment
    • Masuda A, Osada H, Yatabe Y, et al. Protective function of p27 (KIP1) against apoptosis in small cell lung cancer cells in unfavorable microenvironment. Am J Pathol 2001; 158: 87-96.
    • (2001) Am. J. Pathol. , vol.158 , pp. 87-96
    • Masuda, A.1    Osada, H.2    Yatabe, Y.3
  • 9
    • 0033580135 scopus 로고    scopus 로고
    • p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells
    • Eymin B, Haugg M, Droin N, Sordet O, Dimanche-Boitrel MT, Solary E. p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells. Oncogene 1999; 18: 1411-1418.
    • (1999) Oncogene , vol.18 , pp. 1411-1418
    • Eymin, B.1    Haugg, M.2    Droin, N.3    Sordet, O.4    Dimanche-Boitrel, M.T.5    Solary, E.6
  • 10
    • 0342646964 scopus 로고    scopus 로고
    • Synergistic antitumor effect of chemotherapy and antisense-mediated ablation of the cell cycle inhibitor p27KIP-1
    • Achenbach TV, Muller R, Slater EP. Synergistic antitumor effect of chemotherapy and antisense-mediated ablation of the cell cycle inhibitor p27KIP-1. Clin Cancer Res 2000; 6: 3006-3014.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3006-3014
    • Achenbach, T.V.1    Muller, R.2    Slater, E.P.3
  • 12
    • 0033176887 scopus 로고    scopus 로고
    • SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
    • Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nature Cell Biol 1999; 1: 193-199.
    • (1999) Nature Cell Biol. , vol.1 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3    Pagano, M.4
  • 13
    • 0034682818 scopus 로고    scopus 로고
    • Phosphorylation at serine 10, a major phosphorylation site of p27Kip1, increases its protein stability
    • Ishida N, Kitagawa M, Hatakeyama S, Nakayama K. Phosphorylation at serine 10, a major phosphorylation site of p27Kip1, increases its protein stability. J Biol Chem 2000; 275: 25146-25154.
    • (2000) J. Biol. Chem. , vol.275 , pp. 25146-25154
    • Ishida, N.1    Kitagawa, M.2    Hatakeyama, S.3    Nakayama, K.4
  • 14
    • 0037177386 scopus 로고    scopus 로고
    • Phosphorylation of p27Kip1 on Serine 10 is required for its binding to CRM1 and nuclear export
    • Ishida N, Hara T, Kamura T, Yoshida M, Nakayama K, Nakayama KI. Phosphorylation of p27Kip1 on Serine 10 is required for its binding to CRM1 and nuclear export. J Biol Chem 2002; 277: 14355-14358.
    • (2002) J. Biol. Chem. , vol.277 , pp. 14355-14358
    • Ishida, N.1    Hara, T.2    Kamura, T.3    Yoshida, M.4    Nakayama, K.5    Nakayama, K.I.6
  • 15
    • 0036799377 scopus 로고    scopus 로고
    • PKB/Akt mediates cell-cycle progression by phosphorylation of p27Kip1 at threonine 157 and modulation of its cellular localization
    • Shin I, Yakes M, Rojo F, et al PKB/Akt mediates cell-cycle progression by phosphorylation of p27Kip1 at threonine 157 and modulation of its cellular localization. Nature Med 2002; 8: 1145-1152.
    • (2002) Nature Med. , vol.8 , pp. 1145-1152
    • Shin, I.1    Yakes, M.2    Rojo, F.3
  • 16
    • 0037047268 scopus 로고    scopus 로고
    • Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization
    • Fujita N, Sato S, Katayama K, Tsuruo T. Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization. J Biol Chem 2002; 277: 28706-28713.
    • (2002) J. Biol. Chem. , vol.277 , pp. 28706-28713
    • Fujita, N.1    Sato, S.2    Katayama, K.3    Tsuruo, T.4
  • 18
    • 0033063666 scopus 로고    scopus 로고
    • Recombinant E1-deleted adenovirus vector induces apoptosis in two lung cancer cell lines
    • Teramoto S, Matsuse T, Matsui H, Ohga E, Ishii T, Ouchi Y. Recombinant E1-deleted adenovirus vector induces apoptosis in two lung cancer cell lines. Eur Respir J 1999; 13: 1125-1132.
    • (1999) Eur. Respir. J. , vol.13 , pp. 1125-1132
    • Teramoto, S.1    Matsuse, T.2    Matsui, H.3    Ohga, E.4    Ishii, T.5    Ouchi, Y.6
  • 19
    • 0033623439 scopus 로고    scopus 로고
    • Over-expression of p27Kip1 induces growth arrest and apoptosis mediated by changes of pRb expression in lung cancer cell lines
    • Naruse I, Hoshino H, Dobashi K, Minato K, Saito R, Mori M. Over-expression of p27Kip1 induces growth arrest and apoptosis mediated by changes of pRb expression in lung cancer cell lines. Int J Cancer 2000; 88: 377-383.
    • (2000) Int. J. Cancer , vol.88 , pp. 377-383
    • Naruse, I.1    Hoshino, H.2    Dobashi, K.3    Minato, K.4    Saito, R.5    Mori, M.6
  • 20
    • 18644376449 scopus 로고    scopus 로고
    • PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest
    • Lian J, Zubovitz J, Petrocelli T, et al. PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest. Nature Med 2002; 8: 1153-1160.
    • (2002) Nature Med. , vol.8 , pp. 1153-1160
    • Lian, J.1    Zubovitz, J.2    Petrocelli, T.3
  • 21
    • 0033987204 scopus 로고    scopus 로고
    • Involvement of retinoblastoma protein in p27Kip1-induced apoptosis
    • Oh S, Kim TK, Hwang DS, Yim J. Involvement of retinoblastoma protein in p27Kip1-induced apoptosis. Cancer Letts 2000; 148: 105-110.
    • (2000) Cancer Letts. , vol.148 , pp. 105-110
    • Oh, S.1    Kim, T.K.2    Hwang, D.S.3    Yim, J.4
  • 22
    • 0033606960 scopus 로고    scopus 로고
    • Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity
    • Eymin B, Sordet O, Droin N, et al. Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity. Oncogene 1999; 18: 4839-4847.
    • (1999) Oncogene , vol.18 , pp. 4839-4847
    • Eymin, B.1    Sordet, O.2    Droin, N.3
  • 23
    • 0042197268 scopus 로고    scopus 로고
    • Are p27 and p21 cytoplasmic oncoproteins?
    • Blagosklonny MV. Are p27 and p21 cytoplasmic oncoproteins? Cell Cycle 2002; 1: 391-393.
    • (2002) Cell Cycle , vol.1 , pp. 391-393
    • Blagosklonny, M.V.1
  • 24
    • 0037304898 scopus 로고    scopus 로고
    • New roles for p21 and p27 cell-cycle inhibitors: A function for each cell compartment?
    • Coqueret O. New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol 2003; 13: 65-70.
    • (2003) Trends Cell Biol. , vol.13 , pp. 65-70
    • Coqueret, O.1
  • 25
    • 0034745353 scopus 로고    scopus 로고
    • Cytoplasmic localization of p21Cip1/WAD1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
    • Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, Hung MC. Cytoplasmic localization of p21Cip1/WAD1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nature Cell Biol 2001; 3: 245-252.
    • (2001) Nature Cell Biol. , vol.3 , pp. 245-252
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Spohn, B.4    Lee, M.H.5    Hung, M.C.6
  • 26
    • 0037019830 scopus 로고    scopus 로고
    • Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio
    • Javelaud D, Besancon F. Inactivation of p21WAF1 sensitizes cells to apoptosis via an increase of both p14ARF and p53 levels and an alteration of the Bax/Bcl-2 ratio. J Biol Chem 2002; 277: 37949-37954.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37949-37954
    • Javelaud, D.1    Besancon, F.2
  • 27
    • 0035145007 scopus 로고    scopus 로고
    • Adenovirus expressing p27Kip1 induces growth arrest of lung cancer cell lines and suppresses the growth of established lung cancer xenografts
    • Park KH, Seol JY, Yoo CG, et al. Adenovirus expressing p27Kip1 induces growth arrest of lung cancer cell lines and suppresses the growth of established lung cancer xenografts. Lung Cancer 2001; 31: 149-155.
    • (2001) Lung Cancer , vol.31 , pp. 149-155
    • Park, K.H.1    Seol, J.Y.2    Yoo, C.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.