Leukotriene synthesis is required for hedgehog-dependent neurite projection in neuralized embryoid bodies but not for motor neuron differentiation

Stem Cells

Volumn 26, Issue 5, 2008, Pages 1138-1145

  Bijlsma, Maarten F ^a,b   Peppelenbosch, Maikel P ^c   Spek, C Arnold ^a   Roelink, Henk ^b  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Cytoskeleton; Development; Leukotrienes; Neurons; Stem cells

Indexed keywords

ARACHIDONIC ACID; LEUKOTRIENE; LIPOXYGENASE INHIBITOR; PROTEIN GLI; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONATE 5 LIPOXYGENASE; BETA3 TUBULIN, MOUSE; ENZYME INHIBITOR; G PROTEIN COUPLED RECEPTOR; GLI PROTEIN, MOUSE; INDOLE DERIVATIVE; KRUPPEL LIKE FACTOR; SHH PROTEIN, MOUSE; SMO PROTEIN, MOUSE; SONIC HEDGEHOG PROTEIN; TUBULIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; FIBROBLAST; MOUSE; NERVE CELL; NEURITE; NONHUMAN; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; EMBRYO (ANATOMY); ENZYMOLOGY; IN VITRO STUDY; METABOLISM; MOTONEURON; QUAIL;

ERINACEIDAE;

ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACID; CELL DIFFERENTIATION; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; HEDGEHOG PROTEINS; INDOLES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LEUKOTRIENES; MICE; MOTOR NEURONS; NEURITES; QUAIL; RECEPTORS, G-PROTEIN-COUPLED; TUBULIN;

EID: 47949124528     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0841     Document Type: Article

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