-
1
-
-
33947420519
-
Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
-
Bailey D.G., Dresser G.K., Leake B.F., and Kim R.B. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin. Pharmacol. Ther. 81 (2007) 495-502
-
(2007)
Clin. Pharmacol. Ther.
, vol.81
, pp. 495-502
-
-
Bailey, D.G.1
Dresser, G.K.2
Leake, B.F.3
Kim, R.B.4
-
2
-
-
0032793959
-
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
-
Cvetkovic M., Leake B., Fromm M.F., Wilkinson G.R., and Kim R.B. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab. Dispos. 27 (1999) 866-871
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 866-871
-
-
Cvetkovic, M.1
Leake, B.2
Fromm, M.F.3
Wilkinson, G.R.4
Kim, R.B.5
-
3
-
-
0344665555
-
ABC of oral bioavailability: transporters as gatekeepers in the gut
-
Dietrich C.G., Geier A., and Oude Elferink R.P. ABC of oral bioavailability: transporters as gatekeepers in the gut. Gut 52 (2003) 1788-1795
-
(2003)
Gut
, vol.52
, pp. 1788-1795
-
-
Dietrich, C.G.1
Geier, A.2
Oude Elferink, R.P.3
-
4
-
-
0036159433
-
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
-
Dresser G.K., Bailey D.G., Leake B.F., Schwarz U.I., Dawson P.A., Freeman D.J., and Kim R.B. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin. Pharmacol. Ther. 71 (2002) 11-20
-
(2002)
Clin. Pharmacol. Ther.
, vol.71
, pp. 11-20
-
-
Dresser, G.K.1
Bailey, D.G.2
Leake, B.F.3
Schwarz, U.I.4
Dawson, P.A.5
Freeman, D.J.6
Kim, R.B.7
-
5
-
-
33750181267
-
Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with Caco-2 cells
-
Englund G., Rorsman F., Ronnblom A., Karlbom U., Lazorova L., Grasjo J., Kindmark A., and Artursson P. Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with Caco-2 cells. Eur. J. Pharm. Sci. 29 (2006) 269-277
-
(2006)
Eur. J. Pharm. Sci.
, vol.29
, pp. 269-277
-
-
Englund, G.1
Rorsman, F.2
Ronnblom, A.3
Karlbom, U.4
Lazorova, L.5
Grasjo, J.6
Kindmark, A.7
Artursson, P.8
-
6
-
-
25144450046
-
Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport
-
Ito K., Suzuki H., Horie T., and Sugiyama Y. Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport. Pharm. Res. 22 (2005) 1559-1577
-
(2005)
Pharm. Res.
, vol.22
, pp. 1559-1577
-
-
Ito, K.1
Suzuki, H.2
Horie, T.3
Sugiyama, Y.4
-
7
-
-
19444367783
-
In vivo effects of cyclosporine A and ketoconazole on the pharmacokinetics of representative substrate for P-glycoprotein and cytochrome P450 (CYP) 3A in rats
-
Kageyama M., Namiki H., Fukushima H., Ito Y., Shibata N., and Takada K. In vivo effects of cyclosporine A and ketoconazole on the pharmacokinetics of representative substrate for P-glycoprotein and cytochrome P450 (CYP) 3A in rats. Biol. Pharm. Bull. 28 (2005) 316-322
-
(2005)
Biol. Pharm. Bull.
, vol.28
, pp. 316-322
-
-
Kageyama, M.1
Namiki, H.2
Fukushima, H.3
Ito, Y.4
Shibata, N.5
Takada, K.6
-
8
-
-
34548628779
-
Transporter-mediated intestinal absorption of fexofenadine in rats
-
Kikuchi A., Nozawa T., Wakasawa T., Maeda T., and Tamai I. Transporter-mediated intestinal absorption of fexofenadine in rats. Drug Metab. Pharmacokinet. 21 (2006) 308-314
-
(2006)
Drug Metab. Pharmacokinet.
, vol.21
, pp. 308-314
-
-
Kikuchi, A.1
Nozawa, T.2
Wakasawa, T.3
Maeda, T.4
Tamai, I.5
-
9
-
-
4544292987
-
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans
-
Molimard M., Diquet B., and Benedetti M.S. Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans. Fundam. Clin. Pharmacol. 18 (2004) 399-411
-
(2004)
Fundam. Clin. Pharmacol.
, vol.18
, pp. 399-411
-
-
Molimard, M.1
Diquet, B.2
Benedetti, M.S.3
-
10
-
-
0036146666
-
Involvement of mutidrug resistance-associated protein 2 in intestinal secretion of grepafloxacin in rats
-
Naruhashi K., Tamai I., Inoue N., Muraoka H., Sai Y., Suzuki N., and Tsuji A. Involvement of mutidrug resistance-associated protein 2 in intestinal secretion of grepafloxacin in rats. Antimicrob. Agents Chemother. 46 (2002) 344-349
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 344-349
-
-
Naruhashi, K.1
Tamai, I.2
Inoue, N.3
Muraoka, H.4
Sai, Y.5
Suzuki, N.6
Tsuji, A.7
-
11
-
-
1642457252
-
Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human
-
Nozawa T., Imai K., Nezu J., Tsuji A., and Tamai I. Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human. J. Pharmacol. Exp. Ther. 308 (2004) 438-445
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 438-445
-
-
Nozawa, T.1
Imai, K.2
Nezu, J.3
Tsuji, A.4
Tamai, I.5
-
12
-
-
0036839477
-
Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir
-
Perloff M.D., von Moltke L.L., and Greenblatt D.J. Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir. J. Clin. Phrmacol. 42 (2002) 1269-1274
-
(2002)
J. Clin. Phrmacol.
, vol.42
, pp. 1269-1274
-
-
Perloff, M.D.1
von Moltke, L.L.2
Greenblatt, D.J.3
-
13
-
-
4344594700
-
Transport characteristics of fexofenadine in the Caco-2 cell model
-
Petri N., Tannergren C., Rungstad D., and Lennernas H. Transport characteristics of fexofenadine in the Caco-2 cell model. Pharm. Res. 21 (2004) 1398-1404
-
(2004)
Pharm. Res.
, vol.21
, pp. 1398-1404
-
-
Petri, N.1
Tannergren, C.2
Rungstad, D.3
Lennernas, H.4
-
14
-
-
0030915306
-
Restricted intestinal absorption of some beta-lactam antibiotics by an energy-dependent efflux system in rat intestine
-
Saitoh H., Fujisaki H., Aungst B.J., and Miyazaki K. Restricted intestinal absorption of some beta-lactam antibiotics by an energy-dependent efflux system in rat intestine. Pharm. Res. 14 (1997) 645-649
-
(1997)
Pharm. Res.
, vol.14
, pp. 645-649
-
-
Saitoh, H.1
Fujisaki, H.2
Aungst, B.J.3
Miyazaki, K.4
-
15
-
-
0031938630
-
Involvement of intestinal P-glycoprotein in the restricted absorption of methylprednisolone from rat small intestine
-
Saitoh H., Hatakeyama M., Eguchi O., Oda M., and Takada M. Involvement of intestinal P-glycoprotein in the restricted absorption of methylprednisolone from rat small intestine. J. Pharm. Sci. 87 (1998) 73-75
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 73-75
-
-
Saitoh, H.1
Hatakeyama, M.2
Eguchi, O.3
Oda, M.4
Takada, M.5
-
16
-
-
33646263124
-
Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein
-
Shimizu M., Uno T., Sugawara K., and Tateishi T. Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein. Br. J. Clin. Pharmacol. 61 (2006) 538-544
-
(2006)
Br. J. Clin. Pharmacol.
, vol.61
, pp. 538-544
-
-
Shimizu, M.1
Uno, T.2
Sugawara, K.3
Tateishi, T.4
-
17
-
-
0034028814
-
Fexofenadine. A review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria
-
Simpson K., and Jarvis B. Fexofenadine. A review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria. Drugs 59 (2000) 301-321
-
(2000)
Drugs
, vol.59
, pp. 301-321
-
-
Simpson, K.1
Jarvis, B.2
-
18
-
-
22344436690
-
P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion
-
Tahara H., Kusuhara H., Fuse E., and Sugiyama Y. P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion. Drug Metab. Dispos. 33 (2005) 963-968
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 963-968
-
-
Tahara, H.1
Kusuhara, H.2
Fuse, E.3
Sugiyama, Y.4
-
19
-
-
0141569628
-
Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily mRNAS in small intestine
-
Takara K., Ohnishi N., Horibe S., and Yokohama T. Expression profiles of drug-metabolizing enzyme CYP3A and drug efflux transporter multidrug resistance 1 subfamily mRNAS in small intestine. Drug Metab. Dispos. 31 (2003) 1235-1239
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 1235-1239
-
-
Takara, K.1
Ohnishi, N.2
Horibe, S.3
Yokohama, T.4
-
20
-
-
0344687432
-
The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique
-
Tannergren C., Knutson T., Knutson L., and Lennernas H. The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique. Br. J. Clin. Pharmacol. 55 (2003) 182-190
-
(2003)
Br. J. Clin. Pharmacol.
, vol.55
, pp. 182-190
-
-
Tannergren, C.1
Knutson, T.2
Knutson, L.3
Lennernas, H.4
-
21
-
-
0242351210
-
Multiple transport mechanism involved in the intestinal absorption and fires-pass extraction of fexofenadine
-
Tannergren C., Petri N., Knutson L., Hedeland M., Bondesson U., and Lennernas H. Multiple transport mechanism involved in the intestinal absorption and fires-pass extraction of fexofenadine. Clin. Pharmacol. Ther. 74 (2003) 423-436
-
(2003)
Clin. Pharmacol. Ther.
, vol.74
, pp. 423-436
-
-
Tannergren, C.1
Petri, N.2
Knutson, L.3
Hedeland, M.4
Bondesson, U.5
Lennernas, H.6
-
22
-
-
0141815941
-
Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter
-
Volk E.L., and Schneider E. Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter. Cancer Res. 63 (2003) 5538-5543
-
(2003)
Cancer Res.
, vol.63
, pp. 5538-5543
-
-
Volk, E.L.1
Schneider, E.2
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