Restricted intestinal absorption of some β-lactam antibiotics by an energy-dependent efflux system in rat intestine

Pharmaceutical Research

Volumn 14, Issue 5, 1997, Pages 645-649

  Saitoh, Hiroshi ^a,c   Fujisaki, Hiroko ^a   Aungst, Bruce J ^b   Miyazaki, Katsumi ^a  

^a HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

^b DUPONT COMPANY   (United States)

^c HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

Amino group; Lactam antibiotics; Intestinal efflux; Restricted absorption

Indexed keywords

4 AMINOHIPPURIC ACID; AMOXICILLIN; AMPICILLIN; BETA LACTAM ANTIBIOTIC; CEFALEXIN; CEFALORIDINE; CEFOPERAZONE; GLUCOSE; PENICILLIN G; PROBENECID; SODIUM AZIDE; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; INTESTINE ABSORPTION; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSPORT KINETICS;

ANIMALS; ANTI-BACTERIAL AGENTS; BETA-LACTAMS; CALCIUM CHANNEL BLOCKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENERGY METABOLISM; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; P-AMINOHIPPURIC ACID; PROBENECID; RATS; SPECTROPHOTOMETRY, ULTRAVIOLET; URICOSURIC AGENTS; VERAPAMIL;

EID: 0030915306     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012113430539     Document Type: Article

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