Overexpression of human hydroxysteroid (17β) dehydrogenase 2 induces disturbance in skeletal development in young male mice

Journal of Bone and Mineral Research

Volumn 23, Issue 8, 2008, Pages 1217-1226

  Shen, ZhongYi ^a   Peng, ZhiQi ^a,b   Sun, Yi ^a   Väänänen, H Kalervo ^a   Poutanen, Matti ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b Pharmatest Services Ltd   (Finland)

Author keywords

Growth retardation; Hydroxysteroid (17 ) dehydrogenase 2; Sex steroids; Skeletal development; Transgenic mice

Indexed keywords

HYDROXYSTEROID DEHYDROGENASE; HYDROXYSTEROID DEHYDROGENASE 2; OSTEOCALCIN; SOMATOMEDIN C; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BONE DENSITY; BONE DEVELOPMENT; BONE GROWTH; CELL DIFFERENTIATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CORTICAL BONE; DIAPHYSIS; FEMUR; GENE OVEREXPRESSION; GROWTH RETARDATION; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PERIOSTEUM; PREPUBERTY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TESTOSTERONE BLOOD LEVEL; TIBIA; TRABECULAR BONE; TRANSGENIC MOUSE;

17-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; BIOLOGICAL MARKERS; BIOMECHANICS; BODY WEIGHT; BONE DEVELOPMENT; CELL DIFFERENTIATION; FEMUR; GENE EXPRESSION REGULATION; GROWTH PLATE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; OSTEOBLASTS; OSTEOCALCIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TESTOSTERONE; TIBIA; TOMOGRAPHY, X-RAY COMPUTED;

EID: 47849108030     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.080322     Document Type: Article

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