AtRECQ2, a RecQ helicase homologue from Arabidopsis thaliana, is able to disrupt various recombinogenic DNA structures in vitro

Plant Journal

Volumn 55, Issue 3, 2008, Pages 397-405

  Kobbe, Daniela ^a   Blanck, Sandra ^a   Demand, Katharina ^a   Focke, Manfred ^a   Puchta, Holger ^a  

^a UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

D loop; DNA recombination; DNA repair; Holliday junction; RecQ; WRN

Indexed keywords

ARABIDOPSIS PROTEIN; CRUCIFORM DNA; PLANT DNA; RECQ HELICASE;

ARABIDOPSIS; ARTICLE; CHEMISTRY; CONFORMATION; ENZYMOLOGY; ESCHERICHIA COLI; GENETIC RECOMBINATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; PH; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; DNA, CRUCIFORM; DNA, PLANT; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; NUCLEIC ACID CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINATION, GENETIC; RECQ HELICASES;

ARABIDOPSIS; ARABIDOPSIS THALIANA; EUKARYOTA;

EID: 47749108328     PISSN: 09607412     EISSN: 1365313X     Source Type: Journal    
DOI: 10.1111/j.1365-313X.2008.03511.x     Document Type: Article

References (41)

1. Bachrati, C.Z. Hickson, I.D. (2003) RecQ helicases: suppressors of tumorigenesis and premature aging. Biochem. J. 374, 577 606.
2. Bachrati, C.Z. Hickson, I.D. (2006) Analysis of the DNA unwinding activity of RecQ family helicases. Methods Enzymol. 409, 86 100.
3. Bachrati, C.Z., Borts, R.H. Hickson, I.D. (2006) Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase. Nucleic Acids Res. 34, 2269 2279.
4. Bagherieh-Najjar, M.B., de Vries, O.M., Hille, J. Dijkwel, P.P. (2005) Arabidopsis RecQl4A suppresses homologous recombination and modulates DNA damage responses. Plant J. 43, 789 798.
5. Bennett, R.J., Sharp, J.A. Wang, J.C. (1998) Purification and characterization of the Sgs1 DNA helicase activity of Saccharomyces cerevisiae. J. Biol. Chem. 273, 9644 9650.
6. van Brabant, A.J., Ye, T., Sanz, M., German, I.J., Ellis, N.A. Holloman, W.K. (2000) Binding and melting of D-loops by the Bloom syndrome helicase. Biochemistry, 39, 14617 14625.
7. Brosh, R.M. Jr, Orren, D.K., Nehlin, J.O., Ravn, P.H., Kenny, M.K., Machwe, A. Bohr, V.A. (1999) Functional and physical interaction between WRN helicase and human replication protein A. J. Biol. Chem. 274, 18341 18350.
8. Brosh, R.M. Jr, Waheed, J. Sommers, J.A. (2002) Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase. J. Biol. Chem. 277, 23236 23245.
9. Brosh, R.M. Jr, Opresko, P.L. Bohr, V.A. (2006) Enzymatic mechanism of the WRN helicase/nuclease. Methods Enzymol. 409, 52 85.
10. Cheng, W.H., Kusumoto, R., Opresko, P.L., Sui, X., Huang, S., Nicolette, M.L., Paull, T.T., Campisi, J., Seidman, M. Bohr, V.A. (2006) Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links. Nucleic Acids Res. 34, 2751 2760.
11. Constantinou, A., Tarsounas, M., Karow, J.K., Brosh, R.M., Bohr, V.A., Hickson, I.D. West, S.C. (2000) Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Rep. 1, 80 84.
12. Cox, M.M. (2002) The nonmutagenic repair of broken replication forks via recombination. Mutat. Res. 510, 107 120.
13. Garcia, P.L., Liu, Y., Jiricny, J., West, S.C. Janscak, P. (2004) Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide. EMBO J. 23, 2882 2891.
14. Haber, J.E. (1999) DNA recombination: the replication connection. Trends Biochem. Sci. 24, 271 275.
15. Hanada, K. Hickson, I.D. (2007) Molecular genetics of RecQ helicase disorders. Cell. Mol. Life Sci. 64, 2306 2322.
16. Hartung, F. Puchta, H. (2006) The RecQ gene family in plants. J. Plant Physiol. 163, 287 296.
17. Hartung, F., Plchova, H. Puchta, H. (2000) Molecular characterisation of RecQ homologues in Arabidopsis thaliana. Nucleic Acids Res. 28, 4275 4282.
18. Hartung, F., Suer, S., Bergmann, T. Puchta, H. (2006) The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRecQ4A. Nucleic Acids Res. 34, 4438 4448.
19. Hartung, F., Suer, S. Puchta, H. (2007) Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana. Proc. Natl Acad. Sci. USA, 104, 18836 18841.
20. Hickson, I.D. (2003) RecQ helicases: caretakers of the genome. Nature Rev. Cancer, 3, 169 178.
21. Janscak, P., Garcia, P.L., Hamburger, F., Makuta, Y., Shiraishi, K., Imai, Y., Ikeda, H. Bickle, T.A. (2003) Characterization and mutational analysis of the RecQ core of the bloom syndrome protein. J. Mol. Biol. 330, 29 42.
22. Karow, J.K., Constantinou, A., Li, J.L., West, S.C. Hickson, I.D. (2000) The Bloom's syndrome gene product promotes branch migration of Holliday junctions. Proc. Natl Acad. Sci. USA, 97, 6504 6508.
23. Kawasaki, K., Maruyama, S., Nakayama, M., Matsumoto, K. Shibata, T. (2002) Drosophila melanogaster RECQ5/QE DNA helicase: stimulation by GTP binding. Nucleic Acids Res. 30, 3682 3691.
24. Kowalczykowski, S.C. (2000) Initiation of genetic recombination and recombination-dependent replication. Trends Biochem. Sci. 25, 156 165.
25. Lanzetta, P.A., Alvarez, L.J., Reinach, P.S. Candia, O.A. (1979) An improved assay for nanomole amounts of inorganic phosphate. Anal. Biochem. 100, 95 97.
26. Li, B., Conway, N., Navarro, S., Comai, L. Comai, L. (2005) A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis. Nucleic Acids Res. 33, 6861 6867.
27. Macris, M.A., Krejci, L., Bussen, W., Shimamoto, A. Sung, P. (2006) Biochemical characterization of the RECQ4 protein, mutated in Rothmund-Thomson syndrome. DNA Repair, 5, 172 180.
28. Mazin, A.V., Zaitseva, E., Sung, P. Kowalczykowski, S.C. (2000) Tailed duplex DNA is the preferred substrate for Rad51 protein-mediated homologous pairing. EMBO J. 19, 1148 1156.
29. Mohaghegh, P., Karow, J.K., Brosh, R.M. Jr, Bohr, V.A. Hickson, I.D. (2001) The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases. Nucleic Acids Res. 29, 2843 2849.
30. Opresko, P.L., Cheng, W.H. Bohr, V.A. (2004) Junction of RecQ helicase biochemistry and human disease. J. Biol. Chem. 279, 18099 18102.
31. Orren, D.K., Theodore, S. Machwe, A. (2002) The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro. Biochemistry, 41, 13483 13488.
32. Özsoy, A.Z., Sekelsky, J.J. Matson, S.W. (2001) Biochemical characterization of the small isoform of Drosophila melanogaster RECQ5 helicase. Nucleic Acids Res. 29, 2986 2993.
33. Plchova, H., Hartung, F. Puchta, H. (2003) Biochemical characterization of an exonuclease from Arabidopsis thaliana reveals similarities to the DNA exonuclease of the human Werner syndrome protein. J. Biol. Chem. 278, 44128 44138.
34. Puchta, H. (1998) Repair of genomic double-strand breaks in somatic plant cells by one-sided invasion of homologous sequences. Plant J. 13, 331 339.
35. Puchta, H. (2005) The repair of double-strand breaks in plants: mechanisms and consequences for genome evolution. J. Exp. Bot. 56, 1 14.
36. Sambrook, J. Russell, D.W. (2001) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press.
37. Sharma, S., Sommers, J.A., Choudhary, S., Faulkner, J.K., Cui, S., Andreoli, L., Muzzolini, L., Vindigni, A. Brosh, R.M. Jr (2005) Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1. J. Biol. Chem. 280, 28072 28084.
38. Sharma, S., Doherty, K.M. Brosh, R.M. Jr (2006) Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability. Biochem. J. 398, 319 337.
39. Shen, J.C., Gray, M.D., Oshima, J. Loeb, L.A. (1998) Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A. Nucleic Acids Res. 26, 2879 2885.
40. Umezu, K., Nakayama, K. Nakayama, H. (1990) Escherichia coli RecQ protein is a DNA helicase. Proc. Natl Acad. Sci. USA, 87, 5363 5367.
41. Wu, L. Hickson, I.D. (2003) The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature, 426, 870 874.