Antibody-targeted RNase fusion proteins (ImmunoRNases) for cancer therapy

Current Pharmaceutical Biotechnology

Volumn 9, Issue 3, 2008, Pages 231-234

  Krauss, Jürgen ^a   Arndt, Michaela A E ^a   Dübel, Stefan ^b   Rybak, Susanna M ^c  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c Bionanomics LLC   (United States)

Author keywords

Antibody RNase fusion protein; ImmunoRNase; Immunotherapeutics; Onconase ; RNase

Indexed keywords

HYBRID PROTEIN; IMMUNORIBONUCLEASE; MONOCLONAL ANTIBODY; RANPIRNASE; RIBONUCLEASE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANTINEOPLASTIC ACTIVITY; CANCER CHEMOTHERAPY; CANCER PATIENT; CELL KILLING; CLINICAL TRIAL; DRUG CONJUGATION; GENETIC ENGINEERING; HUMAN; IMMUNOGENICITY; IN VITRO STUDY; INTERNALIZATION; MESOTHELIOMA; NONHUMAN; PROTEIN FAMILY; REVIEW;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; HUMANS; IMMUNOCONJUGATES; NEOPLASMS; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; RIBONUCLEASE, PANCREATIC;

ANIMALIA;

EID: 47749097538     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920108784567317     Document Type: Review

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