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Volumn 28, Issue 4, 2008, Pages 385-396

Review article: Probiotics and prebiotics in irritable bowel syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BETA GALACTOSIDASE; BIOLOGICAL MARKER; BUTYRIC ACID; CISAPRIDE; CORTICOTROPIN RELEASING FACTOR; FRUCTOSE; FRUCTOSE OLIGOSACCHARIDE; GALACTOSE OLIGOSACCHARIDE; INTERLEUKIN 10; INTERLEUKIN 6; INULIN; INULIN OLIGOSACCHARIDE; LACTULOSE; METRONIDAZOLE; MORPHINE; PREBIOTIC AGENT; PROBIOTIC AGENT; PROBIOTIC AGENT VSL 3; PROPIONIC ACID; SHORT CHAIN FATTY ACID; SORBITOL; SUBSTANCE P; TUMOR NECROSIS FACTOR; VANILLOID RECEPTOR 1;

EID: 47749090554     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2008.03750.x     Document Type: Review
Times cited : (159)

References (96)
  • 1
    • 0141628734 scopus 로고    scopus 로고
    • The effect of Lactobacillus plantarum 299v on the bacterial composition and metabolic activity in faeces of healthy volunteers: A placebo-controlled study on the onset and duration of effects
    • Goossens D, Jonkers D, Russel M, Stobberingh E, Van Den BA, Stockbrugger R. The effect of Lactobacillus plantarum 299v on the bacterial composition and metabolic activity in faeces of healthy volunteers: a placebo-controlled study on the onset and duration of effects. Aliment Pharmacol Ther 2003 18 : 495 505.
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 495-505
    • Goossens, D.1    Jonkers, D.2    Russel, M.3    Stobberingh, E.4    Van Den, B.A.5    Stockbrugger, R.6
  • 2
    • 0032954214 scopus 로고    scopus 로고
    • Persistence of colonization of human colonic mucosa by a probiotic strain, Lactobacillus rhamnosus GG, after oral consumption
    • Alander M, Satokari R, Korpela R, et al. Persistence of colonization of human colonic mucosa by a probiotic strain, Lactobacillus rhamnosus GG, after oral consumption. Appl Environ Microbiol 1999 65 : 351 4.
    • (1999) Appl Environ Microbiol , vol.65 , pp. 351-4
    • Alander, M.1    Satokari, R.2    Korpela, R.3
  • 3
    • 34249790127 scopus 로고    scopus 로고
    • Small intestinal bacterial overgrowth in patients with irritable bowel syndrome
    • Posserud I, Stotzer PO, Bjornsson E, Abrahamsson H, Simren M. Small intestinal bacterial overgrowth in patients with irritable bowel syndrome. Gut 2007 56 : 802 8.
    • (2007) Gut , vol.56 , pp. 802-8
    • Posserud, I.1    Stotzer, P.O.2    Bjornsson, E.3    Abrahamsson, H.4    Simren, M.5
  • 4
    • 0034894451 scopus 로고    scopus 로고
    • Polymerase chain reaction and denaturing gradient gel electrophoresis monitoring of fecal bifidobacterium populations in a prebiotic and probiotic feeding trial
    • Satokari RM, Vaughan EE, Akkermans AD, Saarela M, De Vos WM. Polymerase chain reaction and denaturing gradient gel electrophoresis monitoring of fecal bifidobacterium populations in a prebiotic and probiotic feeding trial. Syst Appl Microbiol 2001 24 : 227 31.
    • (2001) Syst Appl Microbiol , vol.24 , pp. 227-31
    • Satokari, R.M.1    Vaughan, E.E.2    Akkermans, A.D.3    Saarela, M.4    De Vos, W.M.5
  • 5
    • 0031684010 scopus 로고    scopus 로고
    • Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria
    • Zoetendal EG, Akkermans AD, De Vos WM. Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl Environ Microbiol 1998 64 : 3854 9.
    • (1998) Appl Environ Microbiol , vol.64 , pp. 3854-9
    • Zoetendal, E.G.1    Akkermans, A.D.2    De Vos, W.M.3
  • 7
    • 0032505571 scopus 로고    scopus 로고
    • Abnormal colonic fermentation in irritable bowel syndrome
    • King TS, Elia M, Hunter JO. Abnormal colonic fermentation in irritable bowel syndrome. Lancet 1998 352 : 1187 9.
    • (1998) Lancet , vol.352 , pp. 1187-9
    • King, T.S.1    Elia, M.2    Hunter, J.O.3
  • 9
    • 1842580496 scopus 로고    scopus 로고
    • Lactulose ingestion increases faecal bifidobacterial counts: A randomised double-blind study in healthy humans
    • Bouhnik Y, Attar A, Joly FA, Riottot M, Dyard F, Flourie B. Lactulose ingestion increases faecal bifidobacterial counts: a randomised double-blind study in healthy humans. Eur J Clin Nutr 2004 58 : 462 6.
    • (2004) Eur J Clin Nutr , vol.58 , pp. 462-6
    • Bouhnik, Y.1    Attar, A.2    Joly, F.A.3    Riottot, M.4    Dyard, F.5    Flourie, B.6
  • 10
    • 0021954682 scopus 로고
    • Influence of chronic lactulose ingestion on the colonic metabolism of lactulose in man (an in vivo study)
    • Florent C, Flourie B, Leblond A, et al. Influence of chronic lactulose ingestion on the colonic metabolism of lactulose in man (an in vivo study). J Clin Invest 1985 75 : 608 13.
    • (1985) J Clin Invest , vol.75 , pp. 608-13
    • Florent, C.1    Flourie, B.2    Leblond, A.3
  • 11
    • 16544392539 scopus 로고    scopus 로고
    • The capacity of nondigestible carbohydrates to stimulate fecal bifidobacteria in healthy humans: A double-blind, randomized, placebo-controlled, parallel-group, dose-response relation study
    • Bouhnik Y, Raskine L, Simoneau G, et al. The capacity of nondigestible carbohydrates to stimulate fecal bifidobacteria in healthy humans: a double-blind, randomized, placebo-controlled, parallel-group, dose-response relation study. Am J Clin Nutr 2004 80 : 1658 64.
    • (2004) Am J Clin Nutr , vol.80 , pp. 1658-64
    • Bouhnik, Y.1    Raskine, L.2    Simoneau, G.3
  • 13
    • 0033862083 scopus 로고    scopus 로고
    • Relationships between transit time in man and in vitro fermentation of dietary fiber by fecal bacteria
    • Oufir LE, Barry JL, Flourie B, et al. Relationships between transit time in man and in vitro fermentation of dietary fiber by fecal bacteria. Eur J Clin Nutr 2000 54 : 603 9.
    • (2000) Eur J Clin Nutr , vol.54 , pp. 603-9
    • Oufir, L.E.1    Barry, J.L.2    Flourie, B.3
  • 14
    • 0030882208 scopus 로고    scopus 로고
    • Increasing butyrate concentration in the distal colon by accelerating intestinal transit
    • Lewis SJ, Heaton KW. Increasing butyrate concentration in the distal colon by accelerating intestinal transit. Gut 1997 41 : 245 51.
    • (1997) Gut , vol.41 , pp. 245-51
    • Lewis, S.J.1    Heaton, K.W.2
  • 15
    • 0032714223 scopus 로고    scopus 로고
    • Wheat bran affects the site of fermentation of resistant starch and luminal indexes related to colon cancer risk: A study in pigs
    • Govers MJ, Gannon NJ, Dunshea FR, Gibson PR, Muir JG. Wheat bran affects the site of fermentation of resistant starch and luminal indexes related to colon cancer risk: a study in pigs. Gut 1999 45 : 840 7.
    • (1999) Gut , vol.45 , pp. 840-7
    • Govers, M.J.1    Gannon, N.J.2    Dunshea, F.R.3    Gibson, P.R.4    Muir, J.G.5
  • 16
    • 0025650699 scopus 로고
    • Physicochemical characteristics and flora of diarrhoeal and recovery faeces in children with acute gastro-enteritis in Kenya
    • Fujita K, Kaku M, Yanagase Y, et al. Physicochemical characteristics and flora of diarrhoeal and recovery faeces in children with acute gastro-enteritis in Kenya. Ann Trop Paediatr 1990 10 : 339 45.
    • (1990) Ann Trop Paediatr , vol.10 , pp. 339-45
    • Fujita, K.1    Kaku, M.2    Yanagase, Y.3
  • 17
    • 47749146106 scopus 로고    scopus 로고
    • IBS patients have a poorer quality diet and exercise less than organic GI disease patients or normal controls
    • Irvine EJ, Kim J, Alders GECE. IBS patients have a poorer quality diet and exercise less than organic GI disease patients or normal controls. Gastroenterology 2008 134 : A284.
    • (2008) Gastroenterology , vol.134
    • Irvine, E.J.1    Kim, J.2    Alders, G.E.C.E.3
  • 18
    • 0024340831 scopus 로고
    • Food intolerance and the irritable bowel syndrome
    • Nanda R, James R, Smith H, Dudley CR, Jewell DP. Food intolerance and the irritable bowel syndrome. Gut 1989 30 : 1099 104.
    • (1989) Gut , vol.30 , pp. 1099-104
    • Nanda, R.1    James, R.2    Smith, H.3    Dudley, C.R.4    Jewell, D.P.5
  • 19
    • 0029000350 scopus 로고
    • Management of patients with food intolerance in irritable bowel syndrome: The development and use of an exclusion diet
    • Parker TJ, Naylor SJ, Riordan AM, Hunter JO. Management of patients with food intolerance in irritable bowel syndrome: the development and use of an exclusion diet. J Hum Nutr Diet 1995 8 : 159 66.
    • (1995) J Hum Nutr Diet , vol.8 , pp. 159-66
    • Parker, T.J.1    Naylor, S.J.2    Riordan, A.M.3    Hunter, J.O.4
  • 20
    • 4644287837 scopus 로고    scopus 로고
    • Food elimination based on IgG antibodies in irritable bowel syndrome: A randomised controlled trial
    • Atkinson W, Sheldon TA, Shaath N, Whorwell PJ. Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial. Gut 2004 53 : 1459 64.
    • (2004) Gut , vol.53 , pp. 1459-64
    • Atkinson, W.1    Sheldon, T.A.2    Shaath, N.3    Whorwell, P.J.4
  • 21
    • 0020398686 scopus 로고
    • The fecal microbial population in the irritable bowel syndrome
    • Balsari A, Ceccarelli A, Dubini F. The fecal microbial population in the irritable bowel syndrome. Microbiologica 1982 5 : 185 94.
    • (1982) Microbiologica , vol.5 , pp. 185-94
    • Balsari, A.1    Ceccarelli, A.2    Dubini, F.3
  • 22
    • 0023150160 scopus 로고
    • Instability in the faecal flora of a patient suffering from food-related irritable bowel syndrome
    • Bradley HK, Wyatt GM, Bayliss CE, Hunter JO. Instability in the faecal flora of a patient suffering from food-related irritable bowel syndrome. J Med Microbiol 1987 23 : 29 32.
    • (1987) J Med Microbiol , vol.23 , pp. 29-32
    • Bradley, H.K.1    Wyatt, G.M.2    Bayliss, C.E.3    Hunter, J.O.4
  • 23
    • 12844273701 scopus 로고    scopus 로고
    • Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome - A longitudinal study in IBS and control subjects
    • Matto J, Maunuksela L, Kajander K, et al. Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome - a longitudinal study in IBS and control subjects. FEMS Immunol Med Microbiol 2005 43 : 213 22.
    • (2005) FEMS Immunol Med Microbiol , vol.43 , pp. 213-22
    • Matto, J.1    Maunuksela, L.2    Kajander, K.3
  • 24
    • 0034124615 scopus 로고    scopus 로고
    • Irritable bowel syndrome in general practice: Prevalence, characteristics, and referral
    • Thompson WG, Heaton KW, Smyth GT, Smyth C. Irritable bowel syndrome in general practice: prevalence, characteristics, and referral. Gut 2000 46 : 78 82.
    • (2000) Gut , vol.46 , pp. 78-82
    • Thompson, W.G.1    Heaton, K.W.2    Smyth, G.T.3    Smyth, C.4
  • 25
    • 0031907894 scopus 로고    scopus 로고
    • Antibiotic use, childhood affluence and irritable bowel syndrome (IBS)
    • Mendall MA, Kumar D. Antibiotic use, childhood affluence and irritable bowel syndrome (IBS). Eur J Gastroenterol Hepatol 1998 10 : 59 62.
    • (1998) Eur J Gastroenterol Hepatol , vol.10 , pp. 59-62
    • Mendall, M.A.1    Kumar, D.2
  • 27
    • 13944255868 scopus 로고    scopus 로고
    • Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR
    • Malinen E, Rinttila T, Kajander K, et al. Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR. Am J Gastroenterol 2005 100 : 373 82.
    • (2005) Am J Gastroenterol , vol.100 , pp. 373-82
    • Malinen, E.1    Rinttila, T.2    Kajander, K.3
  • 28
    • 34447104397 scopus 로고    scopus 로고
    • The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects
    • Kassinen A, Krogius-Kurikka L, Makivuokko H, et al. The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects. Gastroenterology 2007 133 : 24 33.
    • (2007) Gastroenterology , vol.133 , pp. 24-33
    • Kassinen, A.1    Krogius-Kurikka, L.2    Makivuokko, H.3
  • 30
    • 0035812167 scopus 로고    scopus 로고
    • In vitro adherence properties of Lactobacillus rhamnosus DR20 and Bifidobacterium lactis DR10 strains and their antagonistic activity against an enterotoxigenic Escherichia coli
    • Gopal PK, Prasad J, Smart J, Gill HS. In vitro adherence properties of Lactobacillus rhamnosus DR20 and Bifidobacterium lactis DR10 strains and their antagonistic activity against an enterotoxigenic Escherichia coli. Int J Food Microbiol 2001 67 : 207 16.
    • (2001) Int J Food Microbiol , vol.67 , pp. 207-16
    • Gopal, P.K.1    Prasad, J.2    Smart, J.3    Gill, H.S.4
  • 31
    • 0032937629 scopus 로고    scopus 로고
    • Purification and characterization of a novel protein produced by Bifidobacterium longum SBT2928 that inhibits the binding of enterotoxigenic Escherichia coli Pb176 (CFA/II) to gangliotetraosylceramide
    • Fujiwara S, Hashiba H, Hirota T, Forstner JF. Purification and characterization of a novel protein produced by Bifidobacterium longum SBT2928 that inhibits the binding of enterotoxigenic Escherichia coli Pb176 (CFA/II) to gangliotetraosylceramide. J Appl Microbiol 1999 86 : 615 21.
    • (1999) J Appl Microbiol , vol.86 , pp. 615-21
    • Fujiwara, S.1    Hashiba, H.2    Hirota, T.3    Forstner, J.F.4
  • 32
    • 0042344991 scopus 로고    scopus 로고
    • Inhibitory effect of probiotic Escherichia coli strain Nissle 1917 on adhesion to and invasion of intestinal epithelial cells by adherent-invasive E. coli strains isolated from patients with Crohn's disease
    • Boudeau J, Glasser AL, Julien S, Colombel JF, Darfeuille-Michaud A. Inhibitory effect of probiotic Escherichia coli strain Nissle 1917 on adhesion to and invasion of intestinal epithelial cells by adherent-invasive E. coli strains isolated from patients with Crohn's disease. Aliment Pharmacol Ther 2003 18 : 45 56.
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 45-56
    • Boudeau, J.1    Glasser, A.L.2    Julien, S.3    Colombel, J.F.4    Darfeuille-Michaud, A.5
  • 33
    • 4143069158 scopus 로고    scopus 로고
    • High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
    • Rfeuille-Michaud A, Boudeau J, Bulois P, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology 2004 127 : 412 21.
    • (2004) Gastroenterology , vol.127 , pp. 412-21
    • Rfeuille-Michaud, A.1    Boudeau, J.2    Bulois, P.3
  • 35
    • 0034831139 scopus 로고    scopus 로고
    • Probiotic bacteria enhance murine and human intestinal epithelial barrier function
    • Madsen K, Cornish A, Soper P, et al. Probiotic bacteria enhance murine and human intestinal epithelial barrier function. Gastroenterology 2001 121 : 580 91.
    • (2001) Gastroenterology , vol.121 , pp. 580-91
    • Madsen, K.1    Cornish, A.2    Soper, P.3
  • 36
    • 0036118586 scopus 로고    scopus 로고
    • Lactobacillus plantarum 299v inhibits Escherichia coli-induced intestinal permeability
    • Mangell P, Nejdfors P, Wang M, et al. Lactobacillus plantarum 299v inhibits Escherichia coli-induced intestinal permeability. Dig Dis Sci 2002 47 : 511 6.
    • (2002) Dig Dis Sci , vol.47 , pp. 511-6
    • Mangell, P.1    Nejdfors, P.2    Wang, M.3
  • 37
    • 0032581102 scopus 로고    scopus 로고
    • Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats
    • Johansson ML, Nobaek S, Berggren A, et al. Survival of Lactobacillus plantarum DSM 9843 (299v), and effect on the short-chain fatty acid content of faeces after ingestion of a rose-hip drink with fermented oats. Int J Food Microbiol 1998 42 : 29 38.
    • (1998) Int J Food Microbiol , vol.42 , pp. 29-38
    • Johansson, M.L.1    Nobaek, S.2    Berggren, A.3
  • 38
    • 0036845692 scopus 로고    scopus 로고
    • Effect of Lactobacillus plantarum 299v on colonic fermentation and symptoms of irritable bowel syndrome
    • Sen S, Mullan MM, Parker TJ, Woolner JT, Tarry SA, Hunter JO. Effect of Lactobacillus plantarum 299v on colonic fermentation and symptoms of irritable bowel syndrome. Dig Dis Sci 2002 47 : 2615 20.
    • (2002) Dig Dis Sci , vol.47 , pp. 2615-20
    • Sen, S.1    Mullan, M.M.2    Parker, T.J.3    Woolner, J.T.4    Tarry, S.A.5    Hunter, J.O.6
  • 40
    • 17644376854 scopus 로고    scopus 로고
    • Do interventions which reduce colonic bacterial fermentation improve symptoms of irritable bowel syndrome?
    • Dear KL, Elia M, Hunter JO. Do interventions which reduce colonic bacterial fermentation improve symptoms of irritable bowel syndrome? Dig Dis Sci 2005 50 : 758 66.
    • (2005) Dig Dis Sci , vol.50 , pp. 758-66
    • Dear, K.L.1    Elia, M.2    Hunter, J.O.3
  • 42
    • 0035038535 scopus 로고    scopus 로고
    • Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat
    • Santos J, Yang PC, Soderholm JD, Benjamin M, Perdue MH. Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat. Gut 2001 48 : 630 6.
    • (2001) Gut , vol.48 , pp. 630-6
    • Santos, J.1    Yang, P.C.2    Soderholm, J.D.3    Benjamin, M.4    Perdue, M.H.5
  • 43
    • 34548107027 scopus 로고    scopus 로고
    • Synergy between Lactobacillus paracasei and its bacterial products to counteract stress-induced gut permeability and sensitivity increase in rats
    • Eutamene H, Lamine F, Chabo C, et al. Synergy between Lactobacillus paracasei and its bacterial products to counteract stress-induced gut permeability and sensitivity increase in rats. J Nutr 2007 137 : 1901 7.
    • (2007) J Nutr , vol.137 , pp. 1901-7
    • Eutamene, H.1    Lamine, F.2    Chabo, C.3
  • 44
    • 33750364231 scopus 로고    scopus 로고
    • Probiotics prevent bacterial translocation and improve intestinal barrier function in rats following chronic psychological stress
    • Zareie M, Johnson-Henry K, Jury J, et al. Probiotics prevent bacterial translocation and improve intestinal barrier function in rats following chronic psychological stress. Gut 2006 55 : 1553 60.
    • (2006) Gut , vol.55 , pp. 1553-60
    • Zareie, M.1    Johnson-Henry, K.2    Jury, J.3
  • 45
    • 33746110481 scopus 로고    scopus 로고
    • Lactobacillus farciminis treatment suppresses stress induced visceral hypersensitivity: A possible action through interaction with epithelial cell cytoskeleton contraction
    • Ait-Belgnaoui A, Han W, Lamine F, et al. Lactobacillus farciminis treatment suppresses stress induced visceral hypersensitivity: a possible action through interaction with epithelial cell cytoskeleton contraction. Gut 2006 55 : 1090 4.
    • (2006) Gut , vol.55 , pp. 1090-4
    • Ait-Belgnaoui, A.1    Han, W.2    Lamine, F.3
  • 47
    • 0038121809 scopus 로고    scopus 로고
    • Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance
    • Mccarthy J, O'mahony L, O'callaghan L, et al. Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance. Gut 2003 52 : 975 80.
    • (2003) Gut , vol.52 , pp. 975-80
    • McCarthy, J.1    O'Mahony, L.2    O'Callaghan, L.3
  • 48
    • 37549072218 scopus 로고    scopus 로고
    • Lactobacillus fermentum ACA-DC 179 displays probiotic potential in vitro and protects against trinitrobenzene sulfonic acid (TNBS)-induced colitis and Salmonella infection in murine models
    • Zoumpopoulou G, Foligne B, Christodoulou K, Grangette C, Pot B, Tsakalidou E. Lactobacillus fermentum ACA-DC 179 displays probiotic potential in vitro and protects against trinitrobenzene sulfonic acid (TNBS)-induced colitis and Salmonella infection in murine models. Int J Food Microbiol 2008 121 : 18 26.
    • (2008) Int J Food Microbiol , vol.121 , pp. 18-26
    • Zoumpopoulou, G.1    Foligne, B.2    Christodoulou, K.3    Grangette, C.4    Pot, B.5    Tsakalidou, E.6
  • 49
    • 10644290669 scopus 로고    scopus 로고
    • Colonic responses to Lactobacillus farciminis treatment in trinitrobenzene sulphonic acid-induced colitis in rats
    • Lamine F, Eutamene H, Fioramonti J, Bueno L, Theodorou V. Colonic responses to Lactobacillus farciminis treatment in trinitrobenzene sulphonic acid-induced colitis in rats. Scand J Gastroenterol 2004 39 : 1250 8.
    • (2004) Scand J Gastroenterol , vol.39 , pp. 1250-8
    • Lamine, F.1    Eutamene, H.2    Fioramonti, J.3    Bueno, L.4    Theodorou, V.5
  • 50
    • 33847109825 scopus 로고    scopus 로고
    • A comparative study of the preventative effects exerted by two probiotics, Lactobacillus reuteri and Lactobacillus fermentum, in the trinitrobenzenesulfonic acid model of rat colitis
    • Peran L, Sierra S, Comalada M, et al. A comparative study of the preventative effects exerted by two probiotics, Lactobacillus reuteri and Lactobacillus fermentum, in the trinitrobenzenesulfonic acid model of rat colitis. Br J Nutr 2007 97 : 96 103.
    • (2007) Br J Nutr , vol.97 , pp. 96-103
    • Peran, L.1    Sierra, S.2    Comalada, M.3
  • 51
    • 40149084454 scopus 로고    scopus 로고
    • Lactic acid bacteria inhibit proinflammatory cytokine expression and bacterial glycosaminoglycan degradation activity in dextran sulfate sodium-induced colitic mice
    • Lee HS, Han SY, Bae EA, et al. Lactic acid bacteria inhibit proinflammatory cytokine expression and bacterial glycosaminoglycan degradation activity in dextran sulfate sodium-induced colitic mice. Int Immunopharmacol 2008 8 : 574 80.
    • (2008) Int Immunopharmacol , vol.8 , pp. 574-80
    • Lee, H.S.1    Han, S.Y.2    Bae, E.A.3
  • 52
    • 10744233159 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis
    • Rachmilewitz D, Katakura K, Karmeli F, et al. Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis. Gastroenterology 2004 126 : 520 8.
    • (2004) Gastroenterology , vol.126 , pp. 520-8
    • Rachmilewitz, D.1    Katakura, K.2    Karmeli, F.3
  • 53
    • 14844349149 scopus 로고    scopus 로고
    • Probiotics ameliorate recurrent Th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells
    • Di GC, Marinaro M, Sanchez M, Strober W, Boirivant M. Probiotics ameliorate recurrent Th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells. J Immunol 2005 174 : 3237 46.
    • (2005) J Immunol , vol.174 , pp. 3237-46
    • Di, G.C.1    Marinaro, M.2    Sanchez, M.3    Strober, W.4    Boirivant, M.5
  • 54
    • 20444503737 scopus 로고    scopus 로고
    • Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin
    • Smits HH, Engering A, Van der KD, et al. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J Allergy Clin Immunol 2005 115 : 1260 7.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 1260-7
    • Smits, H.H.1    Engering, A.2    Van Der, K.D.3
  • 55
    • 0037843521 scopus 로고    scopus 로고
    • Immunomodulatory consequences of oral administration of Lactobacillus rhamnosus strain GG in healthy volunteers
    • Schultz M, Linde HJ, Lehn N, et al. Immunomodulatory consequences of oral administration of Lactobacillus rhamnosus strain GG in healthy volunteers. J Dairy Res 2003 70 : 165 73.
    • (2003) J Dairy Res , vol.70 , pp. 165-73
    • Schultz, M.1    Linde, H.J.2    Lehn, N.3
  • 56
    • 0034537411 scopus 로고    scopus 로고
    • Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG
    • Pessi T, Sutas Y, Hurme M, Isolauri E. Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG. Clin Exp Allergy 2000 30 : 1804 8.
    • (2000) Clin Exp Allergy , vol.30 , pp. 1804-8
    • Pessi, T.1    Sutas, Y.2    Hurme, M.3    Isolauri, E.4
  • 57
    • 44349095801 scopus 로고    scopus 로고
    • Probiotic administration in patients with ileal pouch-anal anastomosis for ulcerative colitis is associated with expansion of mucosal regulatory cells
    • Pronio A, Montesani C, Butteroni C, et al. Probiotic administration in patients with ileal pouch-anal anastomosis for ulcerative colitis is associated with expansion of mucosal regulatory cells. Inflamm Bowel Dis 2008 14 : 662 8.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 662-8
    • Pronio, A.1    Montesani, C.2    Butteroni, C.3
  • 58
    • 0033860601 scopus 로고    scopus 로고
    • Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A double-blind, placebo-controlled trial
    • Gionchetti P, Rizzello F, Venturi A, et al. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology 2000 119 : 305 9.
    • (2000) Gastroenterology , vol.119 , pp. 305-9
    • Gionchetti, P.1    Rizzello, F.2    Venturi, A.3
  • 59
    • 9144254035 scopus 로고    scopus 로고
    • Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis
    • Mimura T, Rizzello F, Helwig U, et al. Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. Gut 2004 53 : 108 14.
    • (2004) Gut , vol.53 , pp. 108-14
    • Mimura, T.1    Rizzello, F.2    Helwig, U.3
  • 60
    • 34547604857 scopus 로고    scopus 로고
    • Irritable bowel syndrome: Bacteria and inflammation - Clinical relevance now
    • Spiller RC. Irritable bowel syndrome: bacteria and inflammation - clinical relevance now. Curr Treat Options Gastroenterol 2007 10 : 312 21.
    • (2007) Curr Treat Options Gastroenterol , vol.10 , pp. 312-21
    • Spiller, R.C.1
  • 61
    • 33748324506 scopus 로고    scopus 로고
    • Transgenomic metabolic interactions in a mouse disease model: Interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation
    • Martin FP, Verdu EF, Wang Y, et al. Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation. J Proteome Res 2006 5 : 2185 93.
    • (2006) J Proteome Res , vol.5 , pp. 2185-93
    • Martin, F.P.1    Verdu, E.F.2    Wang, Y.3
  • 62
    • 20044379763 scopus 로고    scopus 로고
    • Effect of E. coli Nissle 1917 on post-inflammatory visceral sensory function in a rat model
    • Liebregts T, Adam B, Bertel A, et al. Effect of E. coli Nissle 1917 on post-inflammatory visceral sensory function in a rat model. Neurogastroenterol Motil 2005 17 : 410 4.
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 410-4
    • Liebregts, T.1    Adam, B.2    Bertel, A.3
  • 63
    • 30944444119 scopus 로고    scopus 로고
    • Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice
    • Verdu EF, Bercik P, Verma-Gandhu M, et al. Specific probiotic therapy attenuates antibiotic induced visceral hypersensitivity in mice. Gut 2006 55 : 182 90.
    • (2006) Gut , vol.55 , pp. 182-90
    • Verdu, E.F.1    Bercik, P.2    Verma-Gandhu, M.3
  • 64
    • 3242680477 scopus 로고    scopus 로고
    • Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis
    • Wang LH, Fang XC, Pan GZ. Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis. Gut 2004 53 : 1096 101.
    • (2004) Gut , vol.53 , pp. 1096-101
    • Wang, L.H.1    Fang, X.C.2    Pan, G.Z.3
  • 65
    • 46349106355 scopus 로고    scopus 로고
    • Increased capsaicin receptor TRPV1 expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain
    • in press.
    • Akbar A, Yiangou Y, Facer P, Walters JR, Anand P, Ghosh S. Increased capsaicin receptor TRPV1 expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain. Gut 2008 in press.
    • (2008) Gut
    • Akbar, A.1    Yiangou, Y.2    Facer, P.3    Walters, J.R.4    Anand, P.5    Ghosh, S.6
  • 66
    • 33846100339 scopus 로고    scopus 로고
    • Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors
    • Rousseaux C, Thuru X, Gelot A, et al. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nat Med 2007 13 : 35 7.
    • (2007) Nat Med , vol.13 , pp. 35-7
    • Rousseaux, C.1    Thuru, X.2    Gelot, A.3
  • 67
    • 0032854720 scopus 로고    scopus 로고
    • Stool water content and colonic drug absorption: Contrasting effects of lactulose and codeine
    • Hebden JM, Gilchrist PJ, Perkins AC, Wilson CG, Spiller RC. Stool water content and colonic drug absorption: contrasting effects of lactulose and codeine. Pharm Res 1999 16 : 1254 9.
    • (1999) Pharm Res , vol.16 , pp. 1254-9
    • Hebden, J.M.1    Gilchrist, P.J.2    Perkins, A.C.3    Wilson, C.G.4    Spiller, R.C.5
  • 68
    • 0026687667 scopus 로고
    • Scintigraphic demonstration of lactulose-induced accelerated proximal colon transit
    • Barrow L, Steed KP, Spiller RC, et al. Scintigraphic demonstration of lactulose-induced accelerated proximal colon transit. Gastroenterology 1992 103 : 1167 73.
    • (1992) Gastroenterology , vol.103 , pp. 1167-73
    • Barrow, L.1    Steed, K.P.2    Spiller, R.C.3
  • 69
    • 0019779556 scopus 로고
    • The laxative effects of lactulose in normal and constipated subjects
    • Bass P, Dennis S. The laxative effects of lactulose in normal and constipated subjects. J Clin Gastroenterol 1981 3 (Suppl. 1 23 8.
    • (1981) J Clin Gastroenterol , vol.3 , Issue.1 , pp. 23-8
    • Bass, P.1    Dennis, S.2
  • 70
    • 0030781311 scopus 로고    scopus 로고
    • Tolerance and efficacy of polyethylene glycol 3350/electrolyte solution versus lactulose in relieving opiate induced constipation: A double-blinded placebo-controlled trial
    • Freedman MD, Schwartz HJ, Roby R, Fleisher S. Tolerance and efficacy of polyethylene glycol 3350/electrolyte solution versus lactulose in relieving opiate induced constipation: a double-blinded placebo-controlled trial. J Clin Pharmacol 1997 37 : 904 7.
    • (1997) J Clin Pharmacol , vol.37 , pp. 904-7
    • Freedman, M.D.1    Schwartz, H.J.2    Roby, R.3    Fleisher, S.4
  • 71
    • 33644963788 scopus 로고    scopus 로고
    • Low-dose lactulose produces a tonic contraction in the human colon
    • Jouet P, Sabate JM, Cuillerier E, et al. Low-dose lactulose produces a tonic contraction in the human colon. Neurogastroenterol Motil 2006 18 : 45 52.
    • (2006) Neurogastroenterol Motil , vol.18 , pp. 45-52
    • Jouet, P.1    Sabate, J.M.2    Cuillerier, E.3
  • 72
    • 34250765606 scopus 로고    scopus 로고
    • Lactobacillus casei rhamnosus Lcr35 in children with chronic constipation
    • Bu LN, Chang MH, Ni YH, Chen HL, Cheng CC. Lactobacillus casei rhamnosus Lcr35 in children with chronic constipation. Pediatr Int 2007 49 : 485 90.
    • (2007) Pediatr Int , vol.49 , pp. 485-90
    • Bu, L.N.1    Chang, M.H.2    Ni, Y.H.3    Chen, H.L.4    Cheng, C.C.5
  • 73
    • 0025355777 scopus 로고
    • Effect of Lactobacillus GG yoghurt in prevention of antibiotic associated diarrhoea
    • Siitonen S, Vapaatalo H, Salminen S, et al. Effect of Lactobacillus GG yoghurt in prevention of antibiotic associated diarrhoea. Ann Med 1990 22 : 57 9.
    • (1990) Ann Med , vol.22 , pp. 57-9
    • Siitonen, S.1    Vapaatalo, H.2    Salminen, S.3
  • 74
    • 0025266067 scopus 로고
    • Prevention of travellers' diarrhoea by Lactobacillus GG
    • Oksanen PJ, Salminen S, Saxelin M, et al. Prevention of travellers' diarrhoea by Lactobacillus GG. Ann Med 1990 22 : 53 6.
    • (1990) Ann Med , vol.22 , pp. 53-6
    • Oksanen, P.J.1    Salminen, S.2    Saxelin, M.3
  • 75
    • 0034059773 scopus 로고    scopus 로고
    • Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome
    • Nobaek S, Johansson ML, Molin G, Ahrne S, Jeppsson B. Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome. Am J Gastroenterol 2000 95 : 1231 8.
    • (2000) Am J Gastroenterol , vol.95 , pp. 1231-8
    • Nobaek, S.1    Johansson, M.L.2    Molin, G.3    Ahrne, S.4    Jeppsson, B.5
  • 76
    • 33646259477 scopus 로고    scopus 로고
    • Prevalence and temporal stability of selected clostridial groups in irritable bowel syndrome in relation to predominant faecal bacteria
    • Maukonen J, Satokari R, Matto J, Soderlund H, Mattila-Sandholm T, Saarela M. Prevalence and temporal stability of selected clostridial groups in irritable bowel syndrome in relation to predominant faecal bacteria. J Med Microbiol 2006 55 : 625 33.
    • (2006) J Med Microbiol , vol.55 , pp. 625-33
    • Maukonen, J.1    Satokari, R.2    Matto, J.3    Soderlund, H.4    Mattila-Sandholm, T.5    Saarela, M.6
  • 77
    • 0027397765 scopus 로고
    • Administration of different Lactobacillus strains in fermented oatmeal soup: In vivo colonization of human intestinal mucosa and effect on the indigenous flora
    • Johansson ML, Molin G, Jeppsson B, Nobaek S, Ahrne S, Bengmark S. Administration of different Lactobacillus strains in fermented oatmeal soup: in vivo colonization of human intestinal mucosa and effect on the indigenous flora. Appl Environ Microbiol 1993 59 : 15 20.
    • (1993) Appl Environ Microbiol , vol.59 , pp. 15-20
    • Johansson, M.L.1    Molin, G.2    Jeppsson, B.3    Nobaek, S.4    Ahrne, S.5    Bengmark, S.6
  • 78
    • 25844477007 scopus 로고    scopus 로고
    • A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating
    • Kim HJ, Vazquez Roque MI, Camilleri M, et al. A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating. Neurogastroenterol Motil 2005 17 : 687 96.
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 687-96
    • Kim, H.J.1    Mi, V.R.2    Camilleri, M.3
  • 79
    • 15744374565 scopus 로고    scopus 로고
    • Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles
    • O'mahony L, Mccarthy J, Kelly P, et al. Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology 2005 128 : 541 51.
    • (2005) Gastroenterology , vol.128 , pp. 541-51
    • O'Mahony, L.1    McCarthy, J.2    Kelly, P.3
  • 80
    • 36749082433 scopus 로고    scopus 로고
    • Clinical trial: Multispecies probiotic supplementation alleviates the symptoms of irritable bowel syndrome and stabilizes intestinal microbiota
    • Kajander K, Myllyluoma E, Rajilic-Stojanovic M, et al. Clinical trial: multispecies probiotic supplementation alleviates the symptoms of irritable bowel syndrome and stabilizes intestinal microbiota. Aliment Pharmacol Ther 2008 27 : 48 57.
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 48-57
    • Kajander, K.1    Myllyluoma, E.2    Rajilic-Stojanovic, M.3
  • 81
    • 33846027467 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled trial of Lactobacillus GG for abdominal pain disorders in children
    • Gawronska A, Dziechciarz P, Horvath A, Szajewska H. A randomized double-blind placebo-controlled trial of Lactobacillus GG for abdominal pain disorders in children. Aliment Pharmacol Ther 2007 25 : 177 84.
    • (2007) Aliment Pharmacol Ther , vol.25 , pp. 177-84
    • Gawronska, A.1    Dziechciarz, P.2    Horvath, A.3    Szajewska, H.4
  • 82
    • 28944452948 scopus 로고    scopus 로고
    • The efficacy of Lactobacillus reuteri ATCC
    • 55730 in the treatment of patients with irritable bowel syndrome-a double blind, placebo-controlled, randomized study.
    • Niv E, Naftali T, Hallak R, Vaisman N. The efficacy of Lactobacillus reuteri ATCC 55730 in the treatment of patients with irritable bowel syndrome-a double blind, placebo-controlled, randomized study. Clin Nutr 2005 24 : 925 31.
    • (2005) Clin Nutr , vol.24 , pp. 925-31
    • Niv, E.1    Naftali, T.2    Hallak, R.3    Vaisman, N.4
  • 83
    • 0033921870 scopus 로고    scopus 로고
    • Bacterial supplementation in the irritable bowel syndrome. a randomised double-blind placebo-controlled crossover study
    • O'sullivan MA, O'morain CA. Bacterial supplementation in the irritable bowel syndrome. A randomised double-blind placebo-controlled crossover study. Dig Liver Dis 2000 32 : 294 301.
    • (2000) Dig Liver Dis , vol.32 , pp. 294-301
    • O'Sullivan, M.A.1    O'Morain, C.A.2
  • 84
    • 24344472329 scopus 로고    scopus 로고
    • A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: A controlled 6-month intervention
    • Kajander K, Hatakka K, Poussa T, Farkkila M, Korpela R. A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6-month intervention. Aliment Pharmacol Ther 2005 22 : 387 94.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 387-94
    • Kajander, K.1    Hatakka, K.2    Poussa, T.3    Farkkila, M.4    Korpela, R.5
  • 85
    • 23944459103 scopus 로고    scopus 로고
    • The use of Lactobacillus GG in irritable bowel syndrome in children: A double-blind randomized control trial
    • Bausserman M, Michail S. The use of Lactobacillus GG in irritable bowel syndrome in children: a double-blind randomized control trial. J Pediatr 2005 147 : 197 201.
    • (2005) J Pediatr , vol.147 , pp. 197-201
    • Bausserman, M.1    Michail, S.2
  • 86
    • 33745569311 scopus 로고    scopus 로고
    • Efficacy of an encapsulated probiotic Bifidobacterium infantis
    • 35624 in women with irritable bowel syndrome.
    • Whorwell PJ, Altringer L, Morel J, et al. Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. Am J Gastroenterol 2006 101 : 1581 90.
    • (2006) Am J Gastroenterol , vol.101 , pp. 1581-90
    • Whorwell, P.J.1    Altringer, L.2    Morel, J.3
  • 87
    • 24344472329 scopus 로고    scopus 로고
    • A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: A controlled 6-month intervention
    • Kajander K, Hatakka K, Poussa T, Farkkila M, Korpela R. A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6-month intervention. Aliment Pharmacol Ther 2005 22 : 387 94.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 387-94
    • Kajander, K.1    Hatakka, K.2    Poussa, T.3    Farkkila, M.4    Korpela, R.5
  • 88
    • 0028171608 scopus 로고    scopus 로고
    • Brain supplementation in the treatment of irritable bowel syndrome
    • Snook J., Shepherd H.A. Brain supplementation in the treatment of irritable bowel syndrome. Aliment Pharmacol Ther 1997 8 : 511 4.
    • (1997) Aliment Pharmacol Ther , vol.8 , pp. 511-4
    • Snook, J.1    Shepherd, H.A.2
  • 89
    • 0028876803 scopus 로고
    • Effect of wheat bran in treatment of chronic nonorganic constipation. a double-blind controlled trial
    • Badiali D, Corazziari E, Habib FI, et al. Effect of wheat bran in treatment of chronic nonorganic constipation. A double-blind controlled trial. Dig Dis Sci 1995 40 : 349 56.
    • (1995) Dig Dis Sci , vol.40 , pp. 349-56
    • Badiali, D.1    Corazziari, E.2    Habib, F.I.3
  • 90
    • 36249026366 scopus 로고    scopus 로고
    • Effects of symbiotic preparations on constipated irritable bowel syndrome symptoms
    • Dughera L, Elia C, Navino M, Cisaro F. Effects of symbiotic preparations on constipated irritable bowel syndrome symptoms. Acta Biomed 2007 78 : 111 6.
    • (2007) Acta Biomed , vol.78 , pp. 111-6
    • Dughera, L.1    Elia, C.2    Navino, M.3    Cisaro, F.4
  • 91
    • 20044379425 scopus 로고    scopus 로고
    • The placebo effect in irritable bowel syndrome trials: A meta-analysis
    • Patel SM, Stason WB, Legedza A, et al. The placebo effect in irritable bowel syndrome trials: a meta-analysis. Neurogastroenterol Motil 2005 17 : 332 40.
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 332-40
    • Patel, S.M.1    Stason, W.B.2    Legedza, A.3
  • 92
    • 0025001816 scopus 로고
    • Role of fructose-sorbitol malabsorption in the irritable bowel syndrome
    • Nelis GF, Vermeeren MAP, Jansen W. Role of fructose-sorbitol malabsorption in the irritable bowel syndrome. Gastroenterology 1990 99 : 1016 20.
    • (1990) Gastroenterology , vol.99 , pp. 1016-20
    • Nelis, G.F.1    Vermeeren, M.A.P.2    Jansen, W.3
  • 93
    • 0026447936 scopus 로고
    • Symptom provocation in irritable bowel syndrome. Effects of differing doses of fructose-sorbitol
    • Symons P, Jones MP, Kellow JE. Symptom provocation in irritable bowel syndrome. Effects of differing doses of fructose-sorbitol. Scand J Gastroenterol 1992 27 : 940 4.
    • (1992) Scand J Gastroenterol , vol.27 , pp. 940-4
    • Symons, P.1    Jones, M.P.2    Kellow, J.E.3
  • 94
    • 39449089584 scopus 로고    scopus 로고
    • Probiotic prophylaxis in predicted severe acute pancreatitis: A randomised, double-blind, placebo-controlled trial
    • Besselink MG, Van Santvoort HC, Buskens E, et al. Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. Lancet 2008 371 : 651 9.
    • (2008) Lancet , vol.371 , pp. 651-9
    • Besselink, M.G.1    Van Santvoort, H.C.2    Buskens, E.3
  • 95
    • 0141961575 scopus 로고    scopus 로고
    • A randomized, controlled exploratory study of clonidine in diarrhea-predominant irritable bowel syndrome
    • Camilleri M, Kim DY, Mckinzie S, et al. A randomized, controlled exploratory study of clonidine in diarrhea-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol 2003 1 : 111 21.
    • (2003) Clin Gastroenterol Hepatol , vol.1 , pp. 111-21
    • Camilleri, M.1    Kim, D.Y.2    McKinzie, S.3
  • 96
    • 34447298145 scopus 로고    scopus 로고
    • Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: A multicentre, randomized, double-blind, controlled trial
    • Guyonnet D, Chassany O, Ducrotte P, et al. Effect of a fermented milk containing Bifidobacterium animalis DN-173 010 on the health-related quality of life and symptoms in irritable bowel syndrome in adults in primary care: a multicentre, randomized, double-blind, controlled trial. Aliment Pharmacol Ther 2007 26 : 475 86.
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 475-86
    • Guyonnet, D.1    Chassany, O.2    Ducrotte, P.3


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