In vivo determination of tumor oxygenation during growth and in response to carbogen breathing using 15C5-loaded alginate capsules as fluorine-19 magnetic resonance imaging oxygen sensors

International Journal of Radiation Oncology Biology Physics

Volumn 60, Issue 3, 2004, Pages 909-919

  Nöth, Ulrike ^a,d   Rodrigues, Loreta M ^a   Robinson, Simon P ^a   Jork, Anette ^b   Zimmermann, Ulrich ^b   Newell, Barry ^c   Griffiths, John R ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c Farnborough Hospital   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

19F MRI; Carbogen; Hypoxia; Magnetic resonance imaging; Perfluorocarbon; Tumor Po2

Indexed keywords

TUMOR MICROENVIRONMENT; TUMOR OXYGENATION; TUMOR PHYSIOLOGY;

OXYGEN; PHYSIOLOGY; PROBABILITY; SENSORS; TUMORS;

MAGNETIC RESONANCE IMAGING;

ALGINIC ACID; CARBOGEN; CROWN ETHER DERIVATIVE; HYDRALAZINE; NICOTINAMIDE; OXYGEN; PERFLUORO 15 CROWN 5 ETHER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; MICROENVIRONMENT; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROLACTINOMA; RAT; STATISTICAL SIGNIFICANCE; TISSUE OXYGENATION; TUMOR GROWTH; TUMOR NECROSIS; TUMOR VASCULARIZATION; TUMOR VOLUME;

ALGINATES; ANIMALS; CARBON DIOXIDE; CELL HYPOXIA; CROWN ETHERS; FLUORINE; GLUCURONIC ACID; HEXURONIC ACIDS; HYDRALAZINE; MAGNETIC RESONANCE IMAGING; NEOPLASMS; NIACINAMIDE; OXYGEN; PARTIAL PRESSURE; RADIATION-SENSITIZING AGENTS; RATS; RATS, INBRED WF; VASODILATOR AGENTS;

EID: 4744366184     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2004.07.671     Document Type: Article

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