Tumour response to hypercapnia and hyperoxia monitored by FLOOD magnetic resonance imaging

NMR in Biomedicine

Volumn 12, Issue 2, 1999, Pages 98-106

  Robinson, Simon P ^a   Collingridge, David R ^b,c   Howe, Franklyn A ^a   Rodrigues, Loreta M ^a   Chaplin, David J ^b   Griffiths, John R ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b MOUNT VERNON HOSPITAL   (United Kingdom)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blood flow; Carbogen; MRI; Oxygenation; Radiotherapy

Indexed keywords

ANIMAL TISSUE; ARTERIAL OXYGEN TENSION; ARTICLE; BREATHING; CANCER RADIOTHERAPY; CELL HYPOXIA; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FEMALE; HYPERCAPNIA; HYPEROXIA; IMAGE ANALYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGENATION; PRIORITY JOURNAL; PROLACTINOMA; RAT; TUMOR BLOOD FLOW; TUMOR VOLUME; VASODILATATION;

ANIMALS; CARBON DIOXIDE; CELL HYPOXIA; FEMALE; HYDROGEN-ION CONCENTRATION; HYPERCAPNIA; MAGNETIC RESONANCE IMAGING; MONITORING, PHYSIOLOGIC; OXYGEN; PARTIAL PRESSURE; PITUITARY NEOPLASMS; PROLACTINOMA; RADIATION-SENSITIZING AGENTS; RATS; RATS, INBRED WF;

ANIMALIA;

EID: 0032930139     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(199904)12:2<98::AID-NBM556>3.0.CO;2-I     Document Type: Article

References (53)

1. Thomlinson, R. H. and Gray, L. H. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br. J. Cancer 9, 539-549 (1955).
2. Gray, L. H., Conger, A. D., Ebert, M., Hornsey, S. and Scott, O. C. A. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br. J. Radiol. 26, 638-648 (1953).
3. Teicher, B. A., Lazo, J. S. and Sartorelli, A. C. Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells. Cancer Res. 41, 73-81 (1981).
4. Rojas, A., Carl, U. and Reghebi, K. Effect of normobaric oxygen on tumor radiosensitivity: fractionated studies. Int. J. Radiat Oncol. Biol. Phys. 18, 547-553 (1990).
5. Rojas, A. Radiosensitisation with normobaric oxygen and carbogen. Radiother. Oncol. (Suppl.) 20, 65-70 (1991).
6. Chaplin, D. J., Horsman, M. R. and Aoki, D. S. Nicotinamide, Fluosol DA and carbogen: a strategy to reoxygenate acutely and chronically hypoxic cells in vivo. Br. J. Cancer 63, 109-113 (1991).
7. Kjellen, E., Joiner, M. C., Collier, J. M., Johns, H. and Rojas, A. A therapeutic benefit from combining normobaric carbogen or oxygen with nicotinamide in fractionated X-ray treatments. Radiother. Oncol. 22, 81-91 (1991).
8. Grau, C., Horsman, M. R. and Overgaard, J. Improving the radiation response in a C3H mouse mammary carcinoma by normobaric oxygen or carbogen breathing. Int. J. Radiat. Oncol. Biol. Phys. 22, 415-419 (1992).
9. Rider, W. D., Kersesteci, A. G. and Hawkins, N. V., A trial of "orthobaric" oxygen as an adjunct of radiotherapy of bladder cancer. Proceedings of Radiological Society of North America. 5th Scientific Assembly (1969).
10. Rubin, P., Hanley, J., Keys, H. M., Marcial, V. and Brady, L. Carbogen breathing during radiation therapy. Int. J. Radiat. Oncol. Biol. Phys. 5, 1963-1970 (1979).
11. Dische, S., Rojas, A., Rugg, T., Hong, A. and Michael, B. D. Carbogen breathing: a system for use in man. Br. J. Radiol 65, 87-90 (1992).
12. 2) on the in vivo radiation response of a murine sarcoma. Int. J. Radiat. Oncol. Biol. Phys. 2, 903-911 (1977).
13. Chaplin, D. J., Horsman, M. R. and Siemann, D. W. Further evaluation of nicotinamide and carbogen as a strategy to reoxygenate hypoxic cells in vivo: importance of nicotinamide dose and pre-irradiation breathing time. Br. J. Cancer 68, 269-273 (1993).
14. 2 histography. Br. J. Cancer 66, 919-924 (1992).
15. Guichard, M., Lartigau, E., Martin, L., Thomas, C., Weeger, P., Lambin, P., Le Ridant, A. M., Lusinchi, A., Wibault, P., Luboinski, B. and Eschwege, F. Tumour oxygenation after (1) carbogen administration and/or perflubron emulsion administration in tumour xenografts, (2) carbogen administration in patients. Art. Cells, Blood Subs. Immob. Biotech. 22, 1355-1360 (1994).
16. Laurence, V. M., Ward, R., Dennis, I. F. and Bleehen, N. M. Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients. Br. J. Cancer 72, 198-205 (1995).
17. Rojas, A. ARCON: accelerated radiotherapy with carbogen and nicotinamide. Br. J. Radiol. (Suppl.) 24, 174-178 (1992).
18. Saunders, M. and Dische, S. Clinical results of hypoxic cell radiosensitisation from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide. Br. J. Cancer 74 (Suppl XXVII), S271-S278 (1996).
19. McCoy, C. L., McIntyre, D. J. O., Robinson, S. P., Aboagye, E. O. and Griffiths, J. R. Magnetic resonance spectroscopy and imaging methods for measuring tumour and tissue oxygenation. Br. J. Cancer 74 (Suppl. XXVII), S226-S231 (1996).
20. 2 histography. Int. J. Radiat. Oncol. Biol. Phys. 19, 953-961 (1990).
21. Ogawa, S., Lee, T.-M., Nayak, A. S. and Glynn, P. Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields. Magn. Reson. Med. 14, 68-78 (1990).
22. Kwong, K. K., Belliveau, J. W., Chesler, D. A., Goldberg, I. E., Weisskoff, R. M., Poncelet, B. P., Kennedy, D. N., Hoppel, B. E., Cohen, M. S., Turner, R., Cheng, H.-M., Brady, T. J. and Rosen, B. R. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl Acad. Sci. USA 89, 5675-5679 (1992).
23. Turner, R., Jezzard, P., Wen, H., Kwong, K. K., Le Bihan, D., Zeffiro, T. and Balaban, R. S. Functional mapping of the human visual cortex at 4 and 1.5 Tesla using deoxygenation contrast EPI. Magn. Reson. Med. 29, 277-279 (1993).
24. Howe, F. A., Robinson, S. P. and Griffiths, J. R., Discrimination of blood flow and oxygenation changes in rat tumors in response to carbogen breathing. 3rd Annual Meeting of the Society of Magnetic Resonance, Abstr., p. 64 (1995).
25. Robinson, S. P., Howe, F. A. and Griffiths, J. R. Noninvasive monitoring of carbogen-induced changes in tumor blood flow and oxygenation by functional magnetic resonance imaging. Int. J. Radiat. Oncol. Biol. Phys. 33, 855-859 (1995).
26. 31P MRS. NMR Biomed. 9, 208-216 (1996).
27. Robinson, S. P., Rodrigues, L. M., Ojugo, A. S. E., Mcsheehy, P. M. J., Howe, F. A., Griffiths, J. R. The response to carbogen breathing in experimental tumour models monitored by gradient-recalled magnetic resonance imaging. Br. J. Cancer 75, 1000-1006 (1997).
28. 2* and resonance frequency weighted magnetic resonance images of rodent tumours. NMR Biomed. 7, 3-11 (1994).
29. 2*-weighted images during hyperoxia differentiate tumors from normal tissue. Magn. Reson. Med. 33, 318-325 (1995).
30. Lemieux, S. K., Dorie, M. J., Glover, G. H., Moseley, M. M., Brown, J. M. and Spielman, D. M. Tumor response to changes of breathing gas mapped by the functional magnetic resonance imaging technique. 3rd Annual Meeting of the Society of Magnetic Resonance, Abstr., p. 898 (1995).
31. Bhujwalla, Z. M., Shungu, D. C. and Glickson, J. D., Susceptibility maps of tumours and their relationship to histopathological characteristics and flow. 12th Annual Meeting of the Society of Magnetic Resonance in Medicine, Abstr., p. 142 (1993).
32. Vexler, V. S., de Crespigny, A. J. S., Wendland, M. F., Kuwatsuru, R., Muhler, A., Brasch, R. C. and Moseley, M. E. MR imaging of blood oxygenation-dependent changes in focal renal ischemia and transplanted liver tumor in rat. J. Magn. Reson. Imag. 3, 483-490 (1993).
33. Griffiths, J. R., Taylor, N. J., Howe, F. A., Saunders, M. I., Robinson, S. P., Hoskin, P. J., Powell, M. E. B., Thoumine, M., Caine, L. A. and Baddeley, H The response of human tumors to carbogen breathing, monitored by gradient-recalled echo magnetic resonance imaging. Int. J. Radiat. Oncol. Biol. Phys. 39, 697-701 (1997).
34. Prysor-Jones, R. A. and Jenkins, J. S. Effect of bromocriptine on DNA synthesis, growth and hormone secretion of spontaneous pituitary tumours in the rat. J. Endocrinol. 88, 463-469 (1981).
35. Menke, H. and Vaupel, P. Effect of injectable or inhalational anesthetics and of neuroleptic, neuroleptanalgesic, and sedative agents on tumor blood flow. Radiat. Res. 114, 64-76 (1988).
36. 31P MRS of tumour metabolism in anaesthetized vs conscious mice. NMR Biomed. 7, 167-171 (1994).
37. Haase, A., Frahm, J., Matthaei, D., Hanicke, W. and Merboldt, K.-D. FLASH imaging: rapid NMR imaging using low flip angle pulses. J. Magn. Reson. 67, 258-266 (1986).
38. Ganong, W. F. Review of Medical Physiology. Appleton-Lange, Connecticut (1989).
39. Duyn, J. H., Moonen, C. T. W., van Yperen, G. E., de Boer, R. W. and Luyten, P. R. Inflow versus deoxyhaemoglobin effects in "BOLD" functional MRI using gradient echoes at 1.5T. NMR Biomed. 7, 83-88 (1994).
40. Oikawa, H., Al-Hallaq, H. A., Lewis, M. Z., River, J. N., Kovar, D. A. and Karczmar, G. S. Spectroscopic imaging of the water resonance with short repetition time to study tumor response to hyperoxia. Magn. Reson. Med. 38, 27-32 (1997).
41. Tadamura, E., Hatabu, H., Li, W., Prasad, P. V. and Edelman, R. R. Effect of oxygen inhalation on relaxation times in various tissues. J. Magn. Reson. Imag. 7, 220-225 (1997).
42. Day, E. D. Vascular relationships of tumor and host. Prog. Exp. Tumor Res. 4, 57-97 (1964).
43. Vaupel, P., Kallinowski, F. and Okunieff, P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res. 49, 6449-6465 (1989).
44. Brizel, D. M., Lin, S., Johnson, J. L., Brooks, J., Dewhirst, M. W. and Piantadosi, C. A. The mechanisms by which hyperbaric oxygen and carbogen improve tumour oxygenation. Br. J. Cancer 72, 1120-1124 (1995).
45. Dewhirst, M. W., Ong, E. T., Rosner, G. L., Rehmus, S. W., Shan, S., Braun, R. D., Brizel, D. M. and Secomb, T. W. Arteriolar oxygenation in tumour and subcutaneous arterioles: effects of inspired air oxygen content. Br. J. Cancer 74, (Suppl. XXVII), S241-S246 (1996).
46. Brizel, D. M., Hage, W. D., Dodge, R. K., Munley, M. T., Piantadosi, C. A. and Dewhirst, M. W. Hyperbaric oxygen improves tumor radiation response significantly more than carbogen/nicotinamide. Radiat Res. 147, 715-720 (1997).
47. Lyng, H., Sunfor, K., Trope, C. and Rofstad, E. K. Oxygen tension and vascular density in human cervix carcinoma. Br. J. Cancer 74, 1559-1563 (1996).
48. 2, microcirculatory function and radiosensitivity. Int. J. Radiat. Oncol. Biol. Phys. 40, 943-951 (1998).
49. 2) and radiosensitivity. Cancer Res. 56, 5590-5593 (1996).
50. Sasai, K. and Brown, J. M. Discrepancies between measured changes of radiobiological hypoxic fraction and oxygen-tension monitoring using 2 assay systems. Int. J. Radiat. Oncol. Biol. Phys. 30, 355-361 (1994).
51. Abramovitch, R., Frenkiel, D. and Neeman, M. Analysis of subcutaneous angiogenesis by gradient echo magnetic resonance imaging. Magn. Reson. Med. 39, 813-824 (1998).
52. Al-Hallaq, H. A., River, J. N., Zamora, M., Oikawa, H. and Karczmar, G. S. Correlation of magnetic resonance and oxygen microelectrode measurements of carbogen-induced changes in tumour oxygenation. Int. J. Radiat. Oncol. Biol. Phys. 41, 151-159 (1998).
53. 2 using a fibre-optic oxygen sensor in rodent tumours and their response to carbogen breathing. 6th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Abstr., p. 1665 (1998).