Effects of deletion and site-directed mutations on ligation steps of NAD+-dependent DNA ligase: A biochemical analysis of BRCA1 C-terminal domain

Biochemistry

Volumn 43, Issue 39, 2004, Pages 12648-12659

  Feng, Hong ^a   Parker, Jeremy M ^a   Lu, Jing ^a   Cao, Weiguo ^a  

^a CLEMSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; LIGAMENTS; MOLECULAR BIOLOGY; MUTAGENESIS; PROTEINS; SUBSTRATES;

ADENYLATION; DNA STRANDS; LIGATION; SITE-DIRECTED MUTAGENESIS;

DNA;

ADENOSINE PHOSPHATE; NICOTINAMIDE ADENINE DINUCLEOTIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ADENYLATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DNA BINDING; DNA STRAND; ENZYME SUBSTRATE; GEL MOBILITY SHIFT ASSAY; GENE DELETION; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; THERMUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BASE PAIR MISMATCH; BASE SEQUENCE; BRCA1 PROTEIN; DNA LIGASES; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NAD; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; SUBSTRATE SPECIFICITY; THERMUS;

THERMUS;

EID: 4744361819     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049451c     Document Type: Article

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