Nick recognition by DNA ligases

Journal of Molecular Biology

Volumn 296, Issue 1, 2000, Pages 43-56

  Doherty, Aidan J ^a,b   Dafforn, Timothy R ^a,b  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

DNA footprinting; DNA ligase; Molecular modelling; Nick recognition; Photocrosslinking

Indexed keywords

POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA FOOTPRINTING; DNA NICK TRANSLATION; ENZYME ANALYSIS; ENZYME BINDING; ENZYME MECHANISM; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION;

PHOCIDAE;

EID: 0034635347     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3423     Document Type: Article

References (34)

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3. Mutational analysis of messenger RNA capping enzyme identifies amino acids involved in GTP binding, enzyme-guanylate formation, and GMP transfer to RNA
4. Correlation of the enzyme activities of Bacillus stearothermophilus lactate dehydrogenase on three substrates with the results of molecular dynamics/energy minimization conformational searching
5. Photochemical coupling of 5-bromouracil (BU) to a peptide linkage. A model for BU-DNA protein photocrosslinking
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7. Functional domains of ATP-dependent DNA ligases
8. Bacteriophage T7 DNA ligase: Cloning, over-expression, crystallisation and characterisation
9. Characterisation of proteolytic fragments of bacteriophage T7 DNA ligase
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13. Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide-gel electrophoresis
14. X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes
15. Effect of single amino acid changes in the region of the adenylylation site of T4 RNA ligase
16. Expression and characterization of an RNA capping enzyme encoded by Chlorella virus PBCV-1
17. Molecular characterization of a DNA ligase gene of the extremely thermophilic archaeon Desulfurolobus ambivalens shows close phylogenetic relationship to eukaryotic ligases
18. Molscript: A program to produce both detailed and schematic plots of protein structures
19. DNA ligase: Structure, mechanism, and function
20. Raster3D photorealistic molecular graphics
21. OB (oligonucleotide oligosaccharide binding)-fold: Common structural and functional solution for nonhomologous sequences
22. A rapid finite-difference algoritim, utilizing successive over-relaxation to solve the Poisson-Boltzmann equation
23. Vaccinia virus DNA ligase: Specifity, fidelity, and inhibition
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26. RNA capping enzyme and DNA ligase: A superfamily of covalent nucleotidyl transferases
27. Covalent catalysis in nucleotidyl transfer reactions: Essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases
28. Chlorella virus DNA ligase: Nick recognition and mutational analysis
29. Crystal structure of an ATP-dependent ligase from bacteriophage T7
30. Common fold, common function, common origin?
31. Location of the active-site for enzyme-adenylate formation in DNA ligases
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33. Phylogeny of mRNA capping enzymes
34. Photocrosslinking of 5-iodo-uracil-substituted RNA and DNA to proteins