Locking the two ends of tetrapeptidic HTLV-I protease inhibitors inside the enzyme

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 14, 2008, Pages 6880-6890

  Zhang, Meihui ^a,b   Nguyen, Jeffrey Tri ^a   Kumada, Henri Obadja ^a   Kimura, Tooru ^a   Cheng, Maosheng ^b   Hayashi, Yoshio ^a,c   Kiso, Yoshiaki ^a  

^a Center for Frontier Research in Medicinal Science   (Japan)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Aspartic protease inhibitor; ATL; HIV 1; HTLV I

Indexed keywords

PROTEINASE; PROTEINASE INHIBITOR;

ARTICLE; DRUG ACTIVITY; DRUG INHIBITION; DRUG STRUCTURE; GENE MUTATION; HUMAN T CELL LEUKEMIA VIRUS 1; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

HTLV-I INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; PEPTIDES; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 47349104095     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.05.052     Document Type: Article

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