Differential gene expression in the human ciliary epithelium

Progress in Retinal and Eye Research

Volumn 18, Issue 3, 1999, Pages 403-429

  Coca Prados, Miguel ^a   Escribano, Julio ^a   Ortego, Javier ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 MACROGLOBULIN; ANGIOTENSINOGEN; ANTIOXIDANT; APOLIPOPROTEIN D; ATRIAL NATRIURETIC FACTOR; COMPLEMENTARY DNA; FREE RADICAL; FURIN; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HORMONE PRECURSOR; NEUROPEPTIDE; NEUROTENSIN; NEUROTROPHIC FACTOR; PLASMA PROTEIN; PROTEINASE; PROTEINASE INHIBITOR; REGULATOR PROTEIN; RETINOID BINDING PROTEIN; SELENIUM; SELENOPROTEIN;

AQUEOUS HUMOR; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CILIARY BODY; CILIARY BODY EPITHELIUM; CIRCADIAN RHYTHM; DNA SEQUENCE; GENE EXPRESSION; GENE LIBRARY; GENE SEQUENCE; HUMAN; IMMUNOHISTOCHEMISTRY; INTRAOCULAR PRESSURE; MOLECULAR CLONING; NEUROENDOCRINOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN ANGLE GLAUCOMA; PARACRINE SIGNALING; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

EID: 0033056139     PISSN: 13509462     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1350-9462(98)00026-3     Document Type: Review

References (72)

1. Ahmad H., Singh S. V., Srivastava S. K., Awasthi Y. C. Glutathione S-transferase of bovine iris and ciliary body: characterization of isoenzymes. Curr. Eye Res. 8:1989;175-184.
2. Anand-Srivastava M. B. Atrial natriuretic peptide-C receptor and membrane signalling in hypertension. J. Hypertens. 15:1997;815-826.
3. Bal R., Anholt R. R. H. Formation of the extracellular mucous matrix of olfactory neuroepithelium: identification of partially glycosylated and nonglycosylated precursors of olfactomedin. Biochem. 32:1993;1047-1053.
4. Becerra S. P., Sagasti A., Spinella P., Notario V. Pigment epithelium-derived factor (PEDF) behaves like a noninhibitory serpin: Neurotrophic activity does not require the serpin reactive loop. J. Biol. Chem. 270:1995;25992-25999.
5. Braks J. A., Broers C. E., Danger J. M. H. A., Martens G. J. M. Structural organization of the gene encoding the neuroendocrine chaperone 7B2. Eur. J. Biochem. 236:1996;60-67.
6. Brubaker R. F. Flow of aqueous humor in humans. Invest. Ophthalmol. Vis. Sci. 32:1991;3145-3166.
7. Carraway R., Leeman S. E. The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J. Biol. Chem. 248:1973;6854-6861.
8. Carraway R. E., Mitra S. P., Spaulding G. Posttranslational processing of the Neurotensin/Neuromedin-N precursor. Ann. NY Acad. Sci. 668:1992;1-16.
9. Carré D. A., Civan M. M. cGMP modulates transport across the ciliary epithelium. J. Membr. Biol. 146:1995;293-305.
10. Chang A. T., Polansky J. R., Crook R. B. Natriuretic peptide receptors on human trabecular meshwork cells. Curr. Eye Res. 15:1996;137-143.
11. Cole D. F. Secretion of the aqueous humor. Exp. Eye Res. 25(Suppl.):1977;161-176.
12. Constad W. H., Fiore P., Samson C., Cinotti A. A. Use of an angiotensin converting enzyme inhibitor in ocular hypertension and primary open-angle glaucoma. American J. Ophthalmol. 105:1988;674-677.
13. Crook R. B., Chang A. T. Differential regulation of natriuretic peptide receptors on ciliary body epithelial cells. Biochem J. 324:1997;49-55.
14. Eipper B. A., Mains R. E. Peptide α-amidation. Ann. Re. Physiol. 50:1988;333-344.
15. Elbadri A. A., Shaw C., Johnston C. F., Archer D. B., Buchanan K. D. The distribution of neuropeptides in the ocular tissues of several mammals: a comparative study. Comp. Biolchem. Physiol. 100C:1991;625-627.
16. Escribano J., Hernando N., Ghosh S., Crabb J., Coca-Prados M. cDNA from human ocular ciliary epithelium homologous to big-h3 is preferentially expressed as an extracellular protein in the corneal epithelium. J. Cell. Physiol. 160:1994;511-521.
17. Escribano J., Ortego J., Coca-Prados M. Isolation and characterization of cell-specific cDNA clones from a subtractive library of the ocular ciliary body of a single normal human donor: transcription and synthesis of plasma proteins. J. Biochem. 118:1995;921-931.
18. Fernández-Durango R., Ramirez J. M., Trivino A., Sanchez D., Paraiso P., Garcia De Lacoba M., Ramirez A., Salazar J. J., Fernández-Cruz A., Gutkowska J. Experimental glaucoma significally decreases atrial natriuretic factor (ANF) receptors in the ciliary processes of the rabbit eye. Exp. Eye Res. 53:1991;591-596.
19. Fernández-Durango R., Nuñez D. J., Brown M. J. Messenger RNAs encoding the natriuretic peptides and their receptors are expressed in the eye. Exp. Eye Res. 61:1995;723-729.
20. Fournie-Zaluski M. C., Lucas E., Waksman G.et al. Differences in the structural requirements for selective interaction with neutral metalloendopeptidase (enkephalinase) or angiotensin-converting enzyme. Molecular investigation by use of new thiol inhibitors. Eur. J. Biochem. 139:1984;267-274.
21. Fricker L. D. Carboxypeptidase E. Ann. Rev. Physiol. 50:1988;309-321.
22. Gaspar L., Fernández-Durango R., Seidah N. G., Chretien M., Gutkowska J. ANF mRNA is detected by the polymerase chain reaction technique in the chorioidea and bodies but not in the retina of the rat eye. J. Endocrinology. 129:1991;559-561.
23. +-ATPase in the ocular ciliary epithelium. J. Biol. Chem. 265:1990;2935-2940.
24. +-ATPase genes reveals a gradient of isoforms along the nonpigmented ciliary epithelium: Functional implications in aqueous humor secretion. J. Cell. Physiol. 149:1991;184-194.
25. Gully D., Lespy L., Canton M., Rostene W., Kitabgi P., Le Fur G., Maffrand J. P. Effect of the neurotensin receptor antagonist SR48692 on rat blood pressure modulation by neurotensin. Life Sciences. 58:1996;665-674.
26. Hayes R. G., Shaw C., Kitabgi P., Buchanan K. D. Different relative abundance of neurotensin and neuromedin N in bovine ocular tissues. Regul. pept. 39:1992;147-155.
27. Hernández D. E., Simmons K. B., Pfeiffer R. L., Prange A. J., Nemeroff C. H. Intracameral administration of neurotensin induced miosis in the rabbit. Neuropeptides. 4:1983;31-40.
28. Hernando N., Martín-Alonso J. M., Ghosh S., Coca-Prados M. Isolation of a cDNA encoding a glutathione S-transferase (GST) class-π from the bovine ocular ciliary epithelium. Exp. Eye Res. 55:1992;711-718.
29. Hirota A., Kiuchi Y., Nii H., Gregory D. S. Response and level of beta-adrenergic, vasoactive intestinal peptide, and PACAP receptors during the circadian cycle. Invest. Ophthalmol. Vis. Sci. 38:1997;1708-1718.
30. Hollister A. S., Inagami T. Atrial natriuretic factor and hypertension. A review and metaanalysis. Am. J. Hypert. 4:1991;850-865.
31. Iguchi H., Chan J. S., Seidah N. G., Chretien M. Tissue distribution and molecular forms of a novel pituitary protein in the rat. Neuroendocrinology. 39:1984;453-458.
32. Kawahara J., Buzney S. M., Doyle J. W. The role of the aqueous humor in retinoid transport in rabbits. Invest. Opthalmol. Vis. Sci. 33(Suppl.):1992;1007.
33. Kishimoto I., Dubois S. K., Garbrs D. L. The heart communicates with the kidney exclusively through the guanylyl cyclase-A receptor: acute handling of sodium and water in response to volume expansion. Proc. Natl. Acad. Sci. U.S.A. 93:1996;6215-6219.
34. Kislauskis E., Bullock B., McNeil S., Dobner P. R. The rat gene encoding neurotensin and neuromedin N. Structure, tissue-specific expression, and evolution of exon sequences. J. Biol. Chem. 263:1988;4963-4968.
35. Kubota R., Noda S., Wang Y., Minoshima S., Asakawa S., Kudoh J., Mashima Y., Oguchi Y., Shimizu N. A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping. Genomics. 41:1997;360-369.
36. Leeman S. E., Carraway R. E. Neurotensin: discovery, isolation, characterization, synthesis and possible physiological roles. Ann. NY Acad. Sci. 400:1982;1-16.
37. Lin, C., Stone, R. A. and Wax, M. B. (1990) Angiotensin binding sites in rabbit anterior uvea and human ciliary epithelial cells. Invest. Ophthalmol. Vis. Sci. 31, 147-152.
38. Lynch K. B., Peach M. J. Molecular biology of angiotensinogen. Hypertension. 17:1991;263-269.
39. Martín-Alonso J. M., Ghosh S., Coca-Prados M. Cloning of the bovine plasma selenium-dependent glutathione peroxidase (GP) cDNA from the ocular ciliary epithelium: expression of the plasma and cellular forms within the mammalian eye. J. Biochem. 114:1993;284-291.
40. Martín-Alonso J. M., Ghosh S., Hernando N., Crabb J. W., Coca-Prados M. Differential expression of the cellular retinaldehyde-binding protein in bovine ciliary epithelium. Exp. Eye Res. 56:1993;659-669.
41. Martin-Vasallo P., Ghosh S., Coca-Prados M. Expression of Na, K-ATPase alpha subunit isoforms in the human ciliary body and cultured ciliary epithelial cells. J. Cell. Physiol. 141:1989;243-252.
42. Maw M. A., Kennedy B., Knight A., Bridges R., Roth K. E., Mani E. J., Mukkadan J. K., Nancarrow D., Crabb J. W., Denton M. J. Mutation of the gene encoding cellular retinaldehyde-binding protein in autosomal recessive retinitis pigmentosa. Nat. Genet. 17:1997;198-200.
43. Naggert J. K., Fricker L. D., Varlamov O., Nishina P. M., Rouillé Y., Steiner D. F., Carroll R. J., Paigen B. J., Leiter E. H. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity. Nature Genetics. 10:1995;135-142.
44. Nathanson J. A. Atriopeptin-activated guanylate cyclase in the anterior segment. Identification, localization, and effects of atriopeptins on IOP. Invest. Ophthalmol. Vis. Sci. 28:1987;1357-1364.
45. Olins G. M., Spear K. L., Siegel N. R.et al. Inactivation of atrial natriuretic factor by the renal brush border. Biochim. Biophys. Acta. 901:1987;97-100.
46. Ortego J., Escribano J., Patricia Becerra P., Coca-Prados M. Gene expression of the neurotrophic factor PEDF in the human ciliary epithelium: synthesis and secretion into the aqueous humor. Invest. Ophthalmol. Vis. Sci. 37:1996;2759-2767.
47. Ortego J., Escribano J., Crabb J., Coca-Prados M. Identification of a neuropeptide and neuropeptide processing enzymes in aqueous humor confers neuroendocrine features to the human ocular ciliary epithelium. J. Neurochem. 66:1996;787-796.
48. Ortego J., Coca-Prados M. Molecular characterization and differential gene induction of the neuroendocrine specific genes neurotensin, neurotensin receptor, PC1, PC2 and 7B2 in the human ocular ciliary epithelium. J. Neurochem. 69:1997;1829-1839.
49. Ortego J., Escribano J., Coca-Prados M. Gene expression of proteases and protease inhibitors in the human ciliary epithelium: synthesis and secretion. Exp. Eye Res. 65:1997;289-299.
50. Ortego J., Escribano J., Coca-Prados M. Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR, a protein involved in Juvenile Open Angle Glaucoma with homology to Myosin and Olfactomedin. FEBS Letters. 413:1997;349-353.
51. Ortego J., Coca-Prados M. Molecular identification and co-expression of galanin and GalR-1 galanin receptor in the human ocular ciliary epithelium: differential modulation of their expression by the activation of α2- and β2-adrenergic receptors in cultured ciliary epithelial cells. J. Neurochem. 71:1998;2260-2270.
52. Patil R. V., Han Z., Wax M. B. Regulation of water channel activity of aquaporin 1 by arginine vasopressin and atrial natriuretic peptide. Biochem. Biophys. Res. Commun. 238:1997;392-396.
53. Polansky J. R., Fauss D. J., Chen P., Chen H., Lütjen-Drecoll E., Johnson D., Kurtz R. M., Ma Z.-D., Bloom E., Nguyen T. D. Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product. Ophthalmologica. 211:1997;126-139.
54. Prasanna G., Dibas A., Tao W., White K., Yorio T. Regulation of endothelin-1 in human non-pigmented ciliary epithelial cells by tumor necrosis factor-alpha. Exp. Eye Res. 66:1998;9-18.
55. Raviola G. The structural basis of the blood-ocular barriers. Exp. Eye Res. 25(Suppl):1977;27-63.
56. Raviola G., Raviola E. Intercellular junctions in the ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 17:1978;958-981.
57. Roques B. P., Lucas-Soroca E., Chaillet P.,et al. Complete differentiation between enkephalinase and angiotensin-converting enzyme inhibition by retro-thiorphan. Proc. Natl. Acad. Sci. U.S.A. 80:1983;3178-3182.
58. Rostene W. H., Alexander M. J. Neurotensin and neuroendocrine regulation. Frontiers in Neuroendocrinology. 18:1997;115-173.
59. Rouillé Y., Duguay S. J., Lund K., Furuta M., Gong Q., Lipkind G., Oliva A. A. Jr., Chan S. J., Steiner D. F. Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases. Front Neuroendocrinol. 16:1995;322-361.
60. Rovere C., Barbero P., Kitabgi P. Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin. J. Biol. Chem. 271:1996;11368-11375.
61. Saari J. C., Huang J., Possin D. E., Fariss R. N., Leonard J., Garwin G. G., Crabb J. W., Milam A. H. Cellular retinaldehyde-binding protein is expressed by oligodendrocytes in optic nerve and brain. Glia. 21:1997;259-268.
62. Samuelsson-Almen M., Nilsson S. F., Maepea O., Bill A. Effects of atrial natriuretic factor (ANF) on intraocular pressure and aqueous humor flow in the cynomolgus monkey. Exp. Eye Res. 53:1991;253-260.
63. Schlamp C. L., Nickells R. W. Light and dark cause a shift in the spatial expression of a neuropeptide-processing enzyme in the rat retina. J. Neurosci. 16:1996;2164-2171.
64. 2-terminal sequence of a highly conserved human and porcine pituitary protein belonging to a new superfamily. Immunocytochemical localization in pars distalis and pars nervosa of the pituitary and in the supraoptic nucleus of the hypothalamus. Arch. Biochem. Biophys. 225:1983;525-553.
65. Stone E. M., Fingert J. H., Alward W. L., Nguyen T. D., Polansky J. R., Sunden S. L. F., Nishimura D., Clark A. F., Nystuen A., Nichols B. E., Mackey D. A., Ritch R., Kalenak J. W., Craven E. E., Sheffield V. C. Identification of a gene that causes primary open angle glaucoma. Science. 275:1997;668-670.
66. Tanaka K., Masu M., Nakanishi S. Structure and functional expression of the cloned rat neurotensin receptor. Neuron. 4:1990;847-854.
67. Taniwaki T., Becerra S. P., Chader G. J., Schwartz J. P. Pigment epithelium-derived factor is a survival factor for cerebellargranule cells in culture. J. Neurochem. 64:1995;2509-2517.
68. Tao W., Prasanna G., Dimitrijevich S., Yorio T. Endothelin receptor A is expressed and mediates the [Ca2+]i mobilization of cells in human ciliary smooth muscle, ciliary nonpigmented epithelium, and trabecular meshwork. Curr. Eye Res. 17:1998;31-38.
69. Vincent J.-P. Neurotensin receptors: binding properties, transduction pathways, and structure. Cellular and Molecular Neurobiology. 15:1995;501-512.
70. Wagner J., Jan Danser A. H., Derkx F. H., de Jong T. V., Paul M., Mullins J. J., Schalekamp M. A., Ganten D. Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular renin-angiotensin system. British J. Ophthal. 80:1996;159-163.
71. Wiederholt, M. and Stumpff, F. (1998) The trabecular meshwork and aqueous humor reabsorption. In Current Topics in Membranes. The Eye's Aqueous Humor. From Secretion to Glaucoma. (ed. M. M. Civan) Vol. 45, pp. 163-202. Academic Press.
72. Zhu X., Lindberg I. 7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity. J. Cell Biol. 129:1995;1611-1650.