Cytochrome P450 inhibition profile in liver of veal calves administered a combination of 17β-estradiol, clenbuterol, and dexamethasone for growth-promoting purposes

Food and Chemical Toxicology

Volumn 46, Issue 8, 2008, Pages 2849-2855

  Cantiello, Michela ^a   Carletti, Monica ^a   Dacasto, Mauro ^b   Martin, Pascal G P ^c   Pineau, Thierry ^c   Capolongo, Francesca ^b   Gardini, Giulia ^a   Nebbia, Carlo ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b Istituto di Patologia e Igiene Veterinaria   (Italy)

^c CEMAGREF   (France)

Author keywords

Calves; Drug metabolism; Growth promoters; Inhibition; Liver; mRNA expression

Indexed keywords

CLENBUTEROL; CYTOCHROME P450; CYTOCHROME P450 2C; CYTOCHROME P450 3A; DEXAMETHASONE; ESTRADIOL; GROWTH PROMOTOR; MESSENGER RNA; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CALF (BOVINE); CONTROLLED STUDY; CROSS BREEDING; IN VITRO STUDY; LIVER METABOLISM; MALE; MILK; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; WESTERN BLOTTING;

ADRENERGIC BETA-AGONISTS; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CARBOXYLIC ESTER HYDROLASES; CATTLE; CLENBUTEROL; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSOL; DEXAMETHASONE; DNA, COMPLEMENTARY; ENZYME INHIBITORS; ESTRADIOL; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; GROWTH; LIVER; MALE; MICROSOMES, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; RNA; STIMULATION, CHEMICAL; SULFHYDRYL COMPOUNDS;

FRIESIA;

EID: 47249115190     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.05.018     Document Type: Article

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