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Volumn 37, Issue 2, 1997, Pages 67-73

Improved high-performance liquid chromatographic procedure for the separation and quantification of hydrotestosterone metabolites

Author keywords

Cytochrome P 450; HPLC; Testosterone

Indexed keywords

ANDROSTENEDIONE; CORTODOXONE; CYTOCHROME P450 ISOENZYME; DRUG METABOLITE; PHENOBARBITAL; TESTOSTERONE; TESTOSTERONE DERIVATIVE;

EID: 0030918659     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(97)00013-0     Document Type: Article
Times cited : (49)

References (22)
  • 1
    • 0026324283 scopus 로고
    • Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function
    • Arlott MP, Trant JM, Estabrook RW (1991) Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function. Methods Enzymol 206:454-462.
    • (1991) Methods Enzymol , vol.206 , pp. 454-462
    • Arlott, M.P.1    Trant, J.M.2    Estabrook, R.W.3
  • 2
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 3
    • 0000428146 scopus 로고
    • Analysis and characterization of enzymes
    • Ed. AW Hayes. NY: Raven Press, Ltd.
    • Guengerich FP (1989) Analysis and characterization of enzymes. In Principles and Methods of Toxicology, second edition. (Ed. AW Hayes. NY: Raven Press, Ltd., pp. 777-814.
    • (1989) Principles and Methods of Toxicology, Second Edition , pp. 777-814
    • Guengerich, F.P.1
  • 4
    • 0017833012 scopus 로고
    • Steroid hydroxylations catalyzed by cytochrome P-450
    • Gustafsson J-A (1978) Steroid hydroxylations catalyzed by cytochrome P-450. Methods Enzymol 52:377-388.
    • (1978) Methods Enzymol , vol.52 , pp. 377-388
    • Gustafsson, J.-A.1
  • 5
    • 0026801607 scopus 로고    scopus 로고
    • Role of residue 478 as a determinant of the substrate specificity of cytochrome P450 2B1
    • 19992
    • He Y, Balfour CA, Kedzie KM, Halpert JR (19992) Role of residue 478 as a determinant of the substrate specificity of cytochrome P450 2B1. Biochemistry 31:9220-9226.
    • Biochemistry , vol.31 , pp. 9220-9226
    • He, Y.1    Balfour, C.A.2    Kedzie, K.M.3    Halpert, J.R.4
  • 6
    • 0026662330 scopus 로고
    • Brain cytochrome P450 and testosterone metabolism by rat brain subcellular fractions: Presence of cytochrome P450 3A immunoreactive protein in rat brain mitochondria
    • Jayyosi Z, Cooper KO, Thomas PE (1992) Brain cytochrome P450 and testosterone metabolism by rat brain subcellular fractions: Presence of cytochrome P450 3A immunoreactive protein in rat brain mitochondria. Arch Biochem Biophys 298:265-270.
    • (1992) Arch Biochem Biophys , vol.298 , pp. 265-270
    • Jayyosi, Z.1    Cooper, K.O.2    Thomas, P.E.3
  • 7
    • 0024976419 scopus 로고
    • Alteration of mouse cytochrome P450 coh substrate specificity by mutation of a single amino-acid residue
    • Lindberg RLP, Negishi M (1989) Alteration of mouse cytochrome P450 coh substrate specificity by mutation of a single amino-acid residue. Nature 339:632-634.
    • (1989) Nature , vol.339 , pp. 632-634
    • Lindberg, R.L.P.1    Negishi, M.2
  • 9
    • 0023664028 scopus 로고
    • Rat testosterone 7-alpha hydroxylase. Isolation, sequence, and expression of cDNA and its developmental regulation and induction by 3-methylcholanthrene
    • Nagata K, Matsunaga T, Gillette J, Gelbion HV, Gonzalez FJ (1987) Rat testosterone 7-alpha hydroxylase. Isolation, sequence, and expression of cDNA and its developmental regulation and induction by 3-methylcholanthrene. J Biol Chem 262:2787-2793.
    • (1987) J Biol Chem , vol.262 , pp. 2787-2793
    • Nagata, K.1    Matsunaga, T.2    Gillette, J.3    Gelbion, H.V.4    Gonzalez, F.J.5
  • 11
    • 0026452946 scopus 로고
    • Improved sample preparation for the testosterone hydroxylation assay using disposable extraction columns
    • Oesch F, Wagner H, Platt KL, Arand M (1992) Improved sample preparation for the testosterone hydroxylation assay using disposable extraction columns. J Chromatogr 582:232-235.
    • (1992) J Chromatogr , vol.582 , pp. 232-235
    • Oesch, F.1    Wagner, H.2    Platt, K.L.3    Arand, M.4
  • 12
    • 0026766231 scopus 로고
    • Evaluation of loratidine as an inducer of liver microsomal cytochrome P450 in rats and mice
    • Parkinson A, Clement RP, Casciano CN, Cayen MN (1992) Evaluation of loratidine as an inducer of liver microsomal cytochrome P450 in rats and mice. Biochem Pharmacol 43:2169-2182.
    • (1992) Biochem Pharmacol , vol.43 , pp. 2169-2182
    • Parkinson, A.1    Clement, R.P.2    Casciano, C.N.3    Cayen, M.N.4
  • 13
    • 0026781890 scopus 로고
    • Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: Effect on coumarin, dicumarol and testoserone oxidation
    • Pearce R, Greenway D, Parkinson A (1992) Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: Effect on coumarin, dicumarol and testoserone oxidation. Arch Biochem Biophsy 298:211-225.
    • (1992) Arch Biochem Biophsy , vol.298 , pp. 211-225
    • Pearce, R.1    Greenway, D.2    Parkinson, A.3
  • 14
    • 0025734213 scopus 로고
    • Measurement of enzyme activities of cytochrome P-450 isoenzymes by high performance liquid chromatographic analysis of products
    • Reinerink EJM, Doom L, Jansen EHJM, Vanlersel AAJ (1991) Measurement of enzyme activities of cytochrome P-450 isoenzymes by high performance liquid Chromatographic analysis of products. J Chromatogr 553:233-241.
    • (1991) J Chromatogr , vol.553 , pp. 233-241
    • Reinerink, E.J.M.1    Doom, L.2    Jansen, E.H.J.M.3    Vanlersel, A.A.J.4
  • 15
    • 0028811181 scopus 로고
    • Isocratic high-performance liquid chromatographic method for the separation of testosterone metabolites
    • Sanwald P, Blankson EA, Dulery BD, Schoun J, Huebert ND, Dow J (1995) Isocratic high-performance liquid Chromatographic method for the separation of testosterone metabolites. J Chromatogr 672: 207-215.
    • (1995) J Chromatogr , vol.672 , pp. 207-215
    • Sanwald, P.1    Blankson, E.A.2    Dulery, B.D.3    Schoun, J.4    Huebert, N.D.5    Dow, J.6
  • 17
    • 0023778344 scopus 로고
    • Inhibition of steroid 5α-reductase and its effects on testosterone hydroxylation by rat liver microsomal cytochrome P-450
    • Sonderfan AJ, Parkinson A (1988) Inhibition of steroid 5α-reductase and its effects on testosterone hydroxylation by rat liver microsomal cytochrome P-450. Arch Biochem Biophys 265:208-218.
    • (1988) Arch Biochem Biophys , vol.265 , pp. 208-218
    • Sonderfan, A.J.1    Parkinson, A.2
  • 18
    • 0023643411 scopus 로고
    • Regioselective progesterone hydroxylation catalyzed by eleven rat hepatic cytochrome P-450 isozymes
    • Swinney DC, Ryan DE, Thomas PE, Levin W (1987) Regioselective progesterone hydroxylation catalyzed by eleven rat hepatic cytochrome P-450 isozymes. Biochemistry 6:7073-7083.
    • (1987) Biochemistry , vol.6 , pp. 7073-7083
    • Swinney, D.C.1    Ryan, D.E.2    Thomas, P.E.3    Levin, W.4
  • 19
    • 0021350036 scopus 로고
    • Assay of hepatic microsomal testosterone hydroxylases by high-performance liquid chromatography
    • van der Hoeven T (1984) Assay of hepatic microsomal testosterone hydroxylases by high-performance liquid chromatography. Anal Biochem 138:57-65.
    • (1984) Anal Biochem , vol.138 , pp. 57-65
    • Van Der Hoeven, T.1
  • 20
    • 0023837746 scopus 로고
    • Interactions of hepatic cytochromes P-450 with steroid hormones
    • Waxman DJ (1988) Interactions of hepatic cytochromes P-450 with steroid hormones. Biochem Pharmacol 31:71-84.
    • (1988) Biochem Pharmacol , vol.31 , pp. 71-84
    • Waxman, D.J.1
  • 21
    • 0026324284 scopus 로고
    • P450-catalyzed steroid hydroxylation: Assay and product identification by thin-layer chromatography
    • Waxman DJ (1991) P450-catalyzed steroid hydroxylation: Assay and product identification by thin-layer chromatography. Methods Enzymol 206:462-476.
    • (1991) Methods Enzymol , vol.206 , pp. 462-476
    • Waxman, D.J.1
  • 22
    • 0021112308 scopus 로고
    • 19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes
    • 19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes. J Biol Chem 258:8839-8847.
    • (1983) J Biol Chem , vol.258 , pp. 8839-8847
    • Wood, A.W.1    Ryan, D.E.2    Thomas, P.E.3    Levin, W.4


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