A novel sorting nexin modulates endocytic trafficking and α-secretase cleavage of the amyloid precursor protein

Journal of Biological Chemistry

Volumn 283, Issue 21, 2008, Pages 14257-14268

  Schöbel, Susanne ^a   Neumann, Stephanie ^a   Hertweck, Maren ^b   Dislich, Bastian ^a   Kuhn, Peer Hendrik ^a   Kremmer, Elisabeth ^d   Seed, Brian ^e   Baumeister, Ralf ^b,c   Haass, Christian ^a   Lichtenthaler, Stefan F ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Institute of Biology 3   (United States)

^c UNIVERSITY OF FREIBURG   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CELL MEMBRANES; CLONING; GENETIC ENGINEERING; GLYCOPROTEINS;

ALZHEIMER DISEASES; AMYLOID PRECURSOR PROTEINS; CELLULAR MECHANISMS; CONTROL FACTORS; CULTURED CELLS; DO-MAINS; DOMINANT NEGATIVES; DYNAMIN; ECTODOMAIN SHEDDING; ENDOCYTIC PROTEINS; EXPRESSION CLONINGS; PLASMA MEMBRANES; SECRETASE; TRAFFICKING PROTEINS;

PUMPING PLANTS;

ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; DYNAMIN; PHOSPHOPROTEIN; PROTEIN NEXIN; PROTEIN SNX33; PROTEIN SNX9; UNCLASSIFIED DRUG; CARRIER PROTEIN; SECRETASE; SORTING NEXINS; TRANSFERRIN; VESICULAR TRANSPORT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; ENDOCYTOSIS; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TARGETING; ANIMAL; CAENORHABDITIS ELEGANS; CELL LINE; CERCOPITHECUS; CHEMISTRY; GENE EXPRESSION REGULATION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TRANSGENIC ANIMAL;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CARRIER PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; DYNAMINS; ENDOCYTOSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFERRIN; VESICULAR TRANSPORT PROTEINS;

EID: 47249093676     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801531200     Document Type: Article

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