Water-based ligand screening for paramagnetic metalloproteins

Angewandte Chemie - International Edition

Volumn 47, Issue 24, 2008, Pages 4533-4537

  Bertini, Ivano ^a   Fragai, Marco ^a   Luchinat, Claudio ^a   Talluri, Eleonora ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Drug design; Metalloenzymes; Metalloproteins; NMR spectroscopy; Proton relaxation

Indexed keywords

BINDING ENERGY; BINDING SITES; CONCENTRATION (PROCESS); ELECTRIC POWER PLANTS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARAMAGNETIC MATERIALS; PROTEINS; PROTONS;

DRUG DESIGN; METALLOENZYMES; METALLOPROTEINS; NMR SPECTROSCOPY; PROTON RELAXATION;

LIGANDS;

LIGAND; METALLOPROTEIN; NUCLEAR PROTEIN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN PHOSPHATASE 5; WATER;

ARTICLE; CHEMISTRY; DRUG ANTAGONISM; DRUG SCREENING; MAGNETISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

DRUG EVALUATION, PRECLINICAL; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MAGNETICS; METALLOPROTEINS; NUCLEAR PROTEINS; PHOSPHOPROTEIN PHOSPHATASES; WATER;

EID: 47149110009     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200800327     Document Type: Article

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