Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis

Carcinogenesis

Volumn 29, Issue 6, 2008, Pages 1290-1297

  van Boxtel, Ruben ^a   Toonen, Pim W ^a   van Roekel, Henk S ^a   Verheul, Mark ^a   Smits, Bart M G ^a,c   Korving, Jeroen ^a   de Bruin, Alain ^b   Cuppen, Edwin ^a  

^a HUBRECHT INSTITUTE   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHYLNITROSOUREA; PROTEIN MSH6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; GENE DELETION; GENE FREQUENCY; GENE INACTIVATION; GENE INSERTION; GENOMICS; GENOTOXICITY; GERM LINE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MUTAGENESIS; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; RAT;

ALKYLATING AGENTS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOTTING, WESTERN; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; ETHYLNITROSOUREA; GENOTYPE; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; POLYMERASE CHAIN REACTION; RATS;

EID: 46949102955     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn094     Document Type: Article

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