메뉴 건너뛰기




Volumn 189, Issue 1, 2008, Pages 71-77

Minocycline protects motor but not autonomic neurons after cauda equina injury

Author keywords

Apoptosis; Conus medullaris; Neuroprotection; Preganglionic parasympathetic neuron; Spinal cord injury; Ventral root avulsion

Indexed keywords

CASPASE 3; CHOLINE ACETYLTRANSFERASE; MINOCYCLINE;

EID: 46649120495     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-008-1398-5     Document Type: Article
Times cited : (13)

References (46)
  • 1
    • 1542320276 scopus 로고    scopus 로고
    • Differential expression of mGluR5 in human lumbosacral motoneurons
    • Anneser JMH, Ince PG, Shaw PJ, Borasio GD (2004) Differential expression of mGluR5 in human lumbosacral motoneurons. NeuroReport 15:271-273
    • (2004) NeuroReport , vol.15 , pp. 271-273
    • Anneser, J.M.H.1    Ince, P.G.2    Shaw, P.J.3    Borasio, G.D.4
  • 2
    • 33847259174 scopus 로고    scopus 로고
    • At-level neuropathic pain is induced by lumbosacral ventral root avulsion injury and ameliorated by root reimplantation into the spinal cord
    • Bigbee AJ, Hoang TX, Havton LA (2007) At-level neuropathic pain is induced by lumbosacral ventral root avulsion injury and ameliorated by root reimplantation into the spinal cord. Exp Neurol 204:273-282
    • (2007) Exp Neurol , vol.204 , pp. 273-282
    • Bigbee, A.J.1    Hoang, T.X.2    Havton, L.A.3
  • 4
    • 0032588816 scopus 로고    scopus 로고
    • Re-expression of p75NTR by adult motor neurons after axotomy is triggered by retrograde transport of a positive signal from axons regrowing through damaged or denervated peripheral nerve tissue
    • Bussmann KA, Sofroniew MV (1999) Re-expression of p75NTR by adult motor neurons after axotomy is triggered by retrograde transport of a positive signal from axons regrowing through damaged or denervated peripheral nerve tissue. Neuroscience 91:273-281
    • (1999) Neuroscience , vol.91 , pp. 273-281
    • Bussmann, K.A.1    Sofroniew, M.V.2
  • 5
    • 0022981406 scopus 로고
    • Reinnervation of hindlimb muscles after ventral root avulsion and implantation in the lumbar spinal cord in the adult rat
    • Carlstedt T, Lindå H, Cullheim S, Risling M (1986) Reinnervation of hindlimb muscles after ventral root avulsion and implantation in the lumbar spinal cord in the adult rat. Acta Physiol Scand 128:645-646
    • (1986) Acta Physiol Scand , vol.128 , pp. 645-646
    • Carlstedt, T.1    Lindå, H.2    Cullheim, S.3    Risling, M.4
  • 6
    • 0034433905 scopus 로고    scopus 로고
    • Spinal nerve root repair and reimplantation of avulsed ventral roots into the spinal cord after brachial plexus injury
    • Carlstedt T, Anand P, Hallin R, Misra PV, Noren G, Seferlis T (2000) Spinal nerve root repair and reimplantation of avulsed ventral roots into the spinal cord after brachial plexus injury. J Neurosurg 93:237-247
    • (2000) J Neurosurg , vol.93 , pp. 237-247
    • Carlstedt, T.1    Anand, P.2    Hallin, R.3    Misra, P.V.4    Noren, G.5    Seferlis, T.6
  • 7
    • 0035809758 scopus 로고    scopus 로고
    • Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats
    • Chan YM, Wu W, Yip HK, So KF, Oppenheim RW (2001) Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats. Neuroreport 12:541-545
    • (2001) Neuroreport , vol.12 , pp. 541-545
    • Chan, Y.M.1    Wu, W.2    Yip, H.K.3    So, K.F.4    Oppenheim, R.W.5
  • 8
    • 0031278147 scopus 로고    scopus 로고
    • Lumbosacral nerve root avulsion
    • Chin CH, Chew KC (1997) Lumbosacral nerve root avulsion. Injury 28:674-678
    • (1997) Injury , vol.28 , pp. 674-678
    • Chin, C.H.1    Chew, K.C.2
  • 9
    • 0030027461 scopus 로고    scopus 로고
    • Methods for determining numbers of cells and synapses: A case for more uniform standards of review
    • Coggeshall RE, Lekan HA (1996) Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J Comp Neurol 364:6-15
    • (1996) J Comp Neurol , vol.364 , pp. 6-15
    • Coggeshall, R.E.1    Lekan, H.A.2
  • 10
    • 0024374643 scopus 로고
    • Motoneurons reinnervate skeletal muscle after ventral root implantation into the spinal cord of the cat
    • Cullheim S, Carlstedt T, Linda H, Risling M, Ulfhake B (1989) Motoneurons reinnervate skeletal muscle after ventral root implantation into the spinal cord of the cat. Neuroscience 29:725-733
    • (1989) Neuroscience , vol.29 , pp. 725-733
    • Cullheim, S.1    Carlstedt, T.2    Linda, H.3    Risling, M.4    Ulfhake, B.5
  • 11
    • 25844492098 scopus 로고    scopus 로고
    • Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury
    • de Groat WC, Yoshimura N (2006) Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury. Prog Brain Res 152:59-84
    • (2006) Prog Brain Res , vol.152 , pp. 59-84
    • De Groat, W.C.1    Yoshimura, N.2
  • 13
    • 33646598662 scopus 로고    scopus 로고
    • Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury
    • Festoff BW, Ameenuddin S, Arnold PM, Wong A, Santacruz KS, Citron BA (2006) Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury. J Neurochem 97:1314-1326
    • (2006) J Neurochem , vol.97 , pp. 1314-1326
    • Festoff, B.W.1    Ameenuddin, S.2    Arnold, P.M.3    Wong, A.4    Santacruz, K.S.5    Citron, B.A.6
  • 14
    • 0020053068 scopus 로고
    • Afferent and efferent connections of the rat tail flick reflex (a model used to analyze pain control mechanisms)
    • Grossman ML, Basbaum AI, Fields HL (1982) Afferent and efferent connections of the rat tail flick reflex (a model used to analyze pain control mechanisms). J Comp Neurol 206:9-16
    • (1982) J Comp Neurol , vol.206 , pp. 9-16
    • Grossman, M.L.1    Basbaum, A.I.2    Fields, H.L.3
  • 15
    • 0031149046 scopus 로고    scopus 로고
    • The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration
    • Herdegen T, Skene P, Bähr M (1997) The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration. TINS 20:227-231
    • (1997) TINS , vol.20 , pp. 227-231
    • Herdegen, T.1    Skene, P.2    Bähr, M.3
  • 16
    • 25844459516 scopus 로고    scopus 로고
    • Novel repair strategies to restore bladder function following cauda equina/conus medullaris injuries
    • Hoang TX, Havton LA (2006) Novel repair strategies to restore bladder function following cauda equina/conus medullaris injuries. Prog Brain Res 152:195-204
    • (2006) Prog Brain Res , vol.152 , pp. 195-204
    • Hoang, T.X.1    Havton, L.A.2
  • 17
    • 0345017009 scopus 로고    scopus 로고
    • Autonomic and motor neuron death is progressive and parallel in a lumbosacral ventral root avulsion model of cauda equina injury
    • Hoang TX, Nieto JH, Tillakaratne NJK, Havton LA (2003) Autonomic and motor neuron death is progressive and parallel in a lumbosacral ventral root avulsion model of cauda equina injury. J Comp Neurol 467:477-486
    • (2003) J Comp Neurol , vol.467 , pp. 477-486
    • Hoang, T.X.1    Nieto, J.H.2    Tillakaratne, N.J.K.3    Havton, L.A.4
  • 18
    • 33748266273 scopus 로고    scopus 로고
    • Functional reinnervation of the rat lower urinary tract after cauda equina injury and repair
    • 34
    • Hoang TX, Pikov V, Havton LA (2006) Functional reinnervation of the rat lower urinary tract after cauda equina injury and repair. J Neurosci 26(34):8672-8679
    • (2006) J Neurosci , vol.26 , pp. 8672-8679
    • Hoang, T.X.1    Pikov, V.2    Havton, L.A.3
  • 19
    • 3543092682 scopus 로고    scopus 로고
    • Minocycline safety and tolerability in Huntington disease
    • Huntington Study Group
    • Huntington Study Group (2004) Minocycline safety and tolerability in Huntington disease. Neurology 63:547-549
    • (2004) Neurology , vol.63 , pp. 547-549
  • 21
    • 0028269017 scopus 로고
    • Ventral root avulsion: An experimental model of death of adult motor neurons
    • Koliatsos VE, Price WL, Pardo CA, Price DL (1994) Ventral root avulsion: an experimental model of death of adult motor neurons. J Comp Neurol 342:35-44
    • (1994) J Comp Neurol , vol.342 , pp. 35-44
    • Koliatsos, V.E.1    Price, W.L.2    Pardo, C.A.3    Price, D.L.4
  • 22
    • 0029133815 scopus 로고
    • Differential regulation of motor neuron survival and choline acetyltransferase expression following axotomy
    • Kou SY, Chiu AY, Patterson PH (1995) Differential regulation of motor neuron survival and choline acetyltransferase expression following axotomy. J Neurobiol 27:561-572
    • (1995) J Neurobiol , vol.27 , pp. 561-572
    • Kou, S.Y.1    Chiu, A.Y.2    Patterson, P.H.3
  • 23
    • 0024246783 scopus 로고
    • Loss of transmitter-associated enzyme staining following axotomy does not indicate death of brainstem cholinergic neurons
    • Lams BE, Isacson O, Sofroniew MV (1988) Loss of transmitter-associated enzyme staining following axotomy does not indicate death of brainstem cholinergic neurons. Brain Res 475:401-406
    • (1988) Brain Res , vol.475 , pp. 401-406
    • Lams, B.E.1    Isacson, O.2    Sofroniew, M.V.3
  • 25
    • 0032578036 scopus 로고    scopus 로고
    • Characterization of spinal motoneuron degeneration following different types of peripheral nerve injury in neonatal and adult mice
    • Li L, Houenou LJ, Wu W, Lei M, Prevette DM, Oppenheim RW (1998) Characterization of spinal motoneuron degeneration following different types of peripheral nerve injury in neonatal and adult mice. J Comp Neurol 396:158-168
    • (1998) J Comp Neurol , vol.396 , pp. 158-168
    • Li, L.1    Houenou, L.J.2    Wu, W.3    Lei, M.4    Prevette, D.M.5    Oppenheim, R.W.6
  • 26
    • 0036244959 scopus 로고    scopus 로고
    • Effect of lumbar 5 ventral root transection on pain behaviors: A novel rat model for neuropathic pain without axotomy to primary sensory neurons
    • Li L, Xian CJ, Zhong JH, Zhou XF (2002) Effect of lumbar 5 ventral root transection on pain behaviors: A novel rat model for neuropathic pain without axotomy to primary sensory neurons. Exp Neurol 175:23-34
    • (2002) Exp Neurol , vol.175 , pp. 23-34
    • Li, L.1    Xian, C.J.2    Zhong, J.H.3    Zhou, X.F.4
  • 27
    • 0015197354 scopus 로고
    • The axon reaction: A review of the principal features of perikaryal responses to axon injury
    • Lieberman AR (1971) The axon reaction: a review of the principal features of perikaryal responses to axon injury. Int Rev Neurobiol 14:49-124
    • (1971) Int Rev Neurobiol , vol.14 , pp. 49-124
    • Lieberman, A.R.1
  • 28
    • 0037083204 scopus 로고    scopus 로고
    • Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent
    • Martin LJ, Liu Z (2002) Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent. J Neurobiol 50:181-197
    • (2002) J Neurobiol , vol.50 , pp. 181-197
    • Martin, L.J.1    Liu, Z.2
  • 30
    • 23044445185 scopus 로고    scopus 로고
    • Titanium mesh implantation-a method to stabilize the spine and protect the spinal cord following a multilevel laminectomy in the adult rat
    • Nieto JH, Hoang TX, Warner EA, Franchini BT, Westerlund U, Havton LA (2005) Titanium mesh implantation-a method to stabilize the spine and protect the spinal cord following a multilevel laminectomy in the adult rat. J Neurosci Methods 147:1-7
    • (2005) J Neurosci Methods , vol.147 , pp. 1-7
    • Nieto, J.H.1    Hoang, T.X.2    Warner, E.A.3    Franchini, B.T.4    Westerlund, U.5    Havton, L.A.6
  • 31
    • 0028853885 scopus 로고
    • Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion
    • Novikov L, Novikova L, Kellerth J-O (1995) Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion. Neurosci Lett 200:45-48
    • (1995) Neurosci Lett , vol.200 , pp. 45-48
    • Novikov, L.1    Novikova, L.2    Kellerth, J.-O.3
  • 32
    • 14844343640 scopus 로고    scopus 로고
    • Constitutive nuclear localization of activated caspase 3 in subpopulations of the astroglial family of cells
    • Noyan-Ashraf MH, Brandizzi F, Juurlink BHJ (2005) Constitutive nuclear localization of activated caspase 3 in subpopulations of the astroglial family of cells. Glia 49:588-593
    • (2005) Glia , vol.49 , pp. 588-593
    • Noyan-Ashraf, M.H.1    Brandizzi, F.2    Juurlink, B.H.J.3
  • 33
    • 31344482594 scopus 로고    scopus 로고
    • Complement activation after lumbosacral ventral root avulsion injury
    • Ohlsson M, Havton LA (2006) Complement activation after lumbosacral ventral root avulsion injury. Neurosci Lett 394:179-183
    • (2006) Neurosci Lett , vol.394 , pp. 179-183
    • Ohlsson, M.1    Havton, L.A.2
  • 34
    • 33644993675 scopus 로고    scopus 로고
    • Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury
    • Piao ZG, Cho IH, Park CK, Hong JP, Choi SY, Lee SJ, Lee S, Park K, Kim JS, Oh SB (2006) Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury. Pain 121:219-231
    • (2006) Pain , vol.121 , pp. 219-231
    • Piao, Z.G.1    Cho, I.H.2    Park, C.K.3    Hong, J.P.4    Choi, S.Y.5    Lee, S.J.6    Lee, S.7    Park, K.8    Kim, J.S.9    Oh, S.B.10
  • 35
    • 0942287085 scopus 로고    scopus 로고
    • Programmed cell death in amyotrophic lateral sclerosis: A mechanism of pathogenic and therapeutic importance
    • Przedborski S (2004) Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance. Neurologist 10:1-7
    • (2004) Neurologist , vol.10 , pp. 1-7
    • Przedborski, S.1
  • 36
    • 0037622717 scopus 로고    scopus 로고
    • Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy
    • Raghavendra V, Tanga F, Deleo JA (2003) Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J Pharmacol Exp Ther 306:624-630
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 624-630
    • Raghavendra, V.1    Tanga, F.2    Deleo, J.A.3
  • 37
    • 0028868789 scopus 로고
    • Axotomy induces a different modulation of both low-affinity nerve growth factor receptor and choline acetyltransferase between adult rat spinal and brainstem motoneurons
    • Rende M, Giambanco I, Buratta M, Tonali P (1995) Axotomy induces a different modulation of both low-affinity nerve growth factor receptor and choline acetyltransferase between adult rat spinal and brainstem motoneurons. J Comp Neurol 363:249-263
    • (1995) J Comp Neurol , vol.363 , pp. 249-263
    • Rende, M.1    Giambanco, I.2    Buratta, M.3    Tonali, P.4
  • 38
    • 0018960054 scopus 로고
    • Organization of the motoneurons innervating the pelvic muscles of the male rat
    • Schrøder HD (1980) Organization of the motoneurons innervating the pelvic muscles of the male rat. J Comp Neurol 192:567-587
    • (1980) J Comp Neurol , vol.192 , pp. 567-587
    • Schrøder, H.D.1
  • 40
    • 1542376941 scopus 로고    scopus 로고
    • Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury
    • Stirling DP, Khodarahmi K, Liu J, McPhail LT, McBride CB, Steeves JD, Ramer MS, Tetzlaff W (2004) Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury. J Neurosci 24:2182-2190
    • (2004) J Neurosci , vol.24 , pp. 2182-2190
    • Stirling, D.P.1    Khodarahmi, K.2    Liu, J.3    McPhail, L.T.4    McBride, C.B.5    Steeves, J.D.6    Ramer, M.S.7    Tetzlaff, W.8
  • 43
    • 0033083082 scopus 로고    scopus 로고
    • Stereological methods for estimating the total number of neurons and synapses: Issues of precision and bias
    • West MJ (1999) Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias. TINS 22:51-61
    • (1999) TINS , vol.22 , pp. 51-61
    • West, M.J.1
  • 44
  • 45
    • 34447643571 scopus 로고    scopus 로고
    • Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury
    • Yune TY, Lee JY, Jung GY, Kim SJ, Jiang MH, Kim YC, Oh YJ, Markelonis GJ, Oh TH (2007) Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury. J Neurosci 27:7751-7761
    • (2007) J Neurosci , vol.27 , pp. 7751-7761
    • Yune, T.Y.1    Lee, J.Y.2    Jung, G.Y.3    Kim, S.J.4    Jiang, M.H.5    Kim, Y.C.6    Oh, Y.J.7    Markelonis, G.J.8    Oh, T.H.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.