-
1
-
-
45249107325
-
-
WHO, WHO/CDS/TB/2004.331. Geneva, Switzerland: World Health Organization;
-
WHO. WHO report, WHO/CDS/TB/2004.331. Geneva, Switzerland: World Health Organization; 2004.
-
(2004)
WHO report
-
-
-
2
-
-
4644349770
-
Identification and validation of novel drug targets in tuberculosis
-
Duncan K. Identification and validation of novel drug targets in tuberculosis. Curr Pharm Des 2004;10:3185-3194.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 3185-3194
-
-
Duncan, K.1
-
3
-
-
33644991496
-
Global epidemiology of tuberculosis
-
Dye C. Global epidemiology of tuberculosis. Lancet 2006;367:938-940.
-
(2006)
Lancet
, vol.367
, pp. 938-940
-
-
Dye, C.1
-
4
-
-
0026686943
-
Tuberculosis: Commentary on a reemergent killer
-
Bloom BR, Murray CJL. Tuberculosis: commentary on a reemergent killer. Science 1998;257:1055-1064.
-
(1998)
Science
, vol.257
, pp. 1055-1064
-
-
Bloom, B.R.1
Murray, C.J.L.2
-
5
-
-
33645119729
-
Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs - worldwide, 2000-2004
-
CDC Centers for Disease Control and Prevention
-
CDC (Centers for Disease Control and Prevention). Emergence of Mycobacterium tuberculosis with extensive resistance to second-line drugs - worldwide, 2000-2004. MMWR Morb Mortal Wkly Rep 2006;55:301-305.
-
(2006)
MMWR Morb Mortal Wkly Rep
, vol.55
, pp. 301-305
-
-
-
6
-
-
33846657271
-
XDR-TB in South Africa: No time for denial or complacency
-
Singh JA, Upshurs R, Padayatchi N. XDR-TB in South Africa: no time for denial or complacency. PLoS Med 2007;4:e50.
-
(2007)
PLoS Med
, vol.4
-
-
Singh, J.A.1
Upshurs, R.2
Padayatchi, N.3
-
7
-
-
0028006393
-
(6S)-6-fluoroshikimic acid, an antibacterial agent acting on the aromatic biosynthetic pathway
-
Davies GM, Barret-Bee KJ, Jude DA, Lehan M, Nichols WW, Pinder PE, Thain JL, Watkins WJ, Wilson RG. (6S)-6-fluoroshikimic acid, an antibacterial agent acting on the aromatic biosynthetic pathway. Antimicrob Agents Chemother 1994;38:403-406.
-
(1994)
Antimicrob Agents Chemother
, vol.38
, pp. 403-406
-
-
Davies, G.M.1
Barret-Bee, K.J.2
Jude, D.A.3
Lehan, M.4
Nichols, W.W.5
Pinder, P.E.6
Thain, J.L.7
Watkins, W.J.8
Wilson, R.G.9
-
8
-
-
0003164468
-
The shikimate pathway as a target for herbicides
-
Dodge A, editor, Cambridge, UK: Cambridge University Press;
-
Coggins JR. The shikimate pathway as a target for herbicides. In: Dodge A, editor. Herbicides and plant metabolism. Cambridge, UK: Cambridge University Press; 1989. pp 97-112.
-
(1989)
Herbicides and plant metabolism
, pp. 97-112
-
-
Coggins, J.R.1
-
9
-
-
0025581736
-
The shikimate pathway - metabolic tree with many branches
-
Bentley R. The shikimate pathway - metabolic tree with many branches. Crit Rev Biochem Mol Biol 1990;25:307-384.
-
(1990)
Crit Rev Biochem Mol Biol
, vol.25
, pp. 307-384
-
-
Bentley, R.1
-
10
-
-
0037083107
-
The shikimate pathway and its branches in apicomplexan parasites
-
Roberts CW, Roberts F, Lyons RE, Kirisits MJ, Mui EJ, Finnerty J, Johnson JJ, Ferguson DJ, Coggins JR, Krell T, Coombs GH, Milhous WK, Kyle DE, Tzipori S, Barnwell J, Dame JB, Carlton J, McLeod R. The shikimate pathway and its branches in apicomplexan parasites. J Infect Dis 2002;185:S25-S36.
-
(2002)
J Infect Dis
, vol.185
-
-
Roberts, C.W.1
Roberts, F.2
Lyons, R.E.3
Kirisits, M.J.4
Mui, E.J.5
Finnerty, J.6
Johnson, J.J.7
Ferguson, D.J.8
Coggins, J.R.9
Krell, T.10
Coombs, G.H.11
Milhous, W.K.12
Kyle, D.E.13
Tzipori, S.14
Barnwell, J.15
Dame, J.B.16
Carlton, J.17
McLeod, R.18
-
12
-
-
0000055469
-
Nutrition, growth and metabolism
-
Ratledge C, Stanford JL, editors, London: Academic Press;
-
Ratledge C. Nutrition, growth and metabolism. In: Ratledge C, Stanford JL, editors. The biology of the Mycobacteria, Vol. 1. London: Academic Press; 1982. pp 185-271.
-
(1982)
The biology of the Mycobacteria
, vol.1
, pp. 185-271
-
-
Ratledge, C.1
-
13
-
-
0036773752
-
The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis
-
Parish T, Stoker NG. The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis. Microbiology 2002;148:3069-3077.
-
(2002)
Microbiology
, vol.148
, pp. 3069-3077
-
-
Parish, T.1
Stoker, N.G.2
-
14
-
-
0038265866
-
Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities
-
Michel G, Roszak AW, Sauve V, Maclean J, Matte A, Coggins JR, Cygler M, Lapthorn AJ. Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities. J Biol Chem 2003;278:19463-19472.
-
(2003)
J Biol Chem
, vol.278
, pp. 19463-19472
-
-
Michel, G.1
Roszak, A.W.2
Sauve, V.3
Maclean, J.4
Matte, A.5
Coggins, J.R.6
Cygler, M.7
Lapthorn, A.J.8
-
15
-
-
0042665195
-
Crystal structure of shikimate 5-dehydrogenase (Sdh) bound to Nadp: Insights into function and evolution
-
Padyana AK, Burley SK. Crystal structure of shikimate 5-dehydrogenase (Sdh) bound to Nadp: insights into function and evolution. Structure 2003;11:1005-10013.
-
(2003)
Structure
, vol.11
, pp. 1005-10013
-
-
Padyana, A.K.1
Burley, S.K.2
-
16
-
-
0038154081
-
The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode
-
Ye S, Von Delft F, Brooun A, Knuth MW, Swanson RV, McRee DE. The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode. J Bacteriol 2003;185:4144-4151.
-
(2003)
J Bacteriol
, vol.185
, pp. 4144-4151
-
-
Ye, S.1
Von Delft, F.2
Brooun, A.3
Knuth, M.W.4
Swanson, R.V.5
McRee, D.E.6
-
17
-
-
33749396618
-
Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori
-
Han C, Wang L, Yu K, Chen L, Hu L, Chen K, Jiang H, Shen X. Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori. FEBS J 2006;273:4682-4692.
-
(2006)
FEBS J
, vol.273
, pp. 4682-4692
-
-
Han, C.1
Wang, L.2
Yu, K.3
Chen, L.4
Hu, L.5
Chen, K.6
Jiang, H.7
Shen, X.8
-
18
-
-
0036424063
-
-
Magalhães MLB, Pereira CP, Basso LA, Santos DS, Cloning and expression of functional shikimate dehydrogenase (EC 1.1.1.25) from Mycobacterium tuberculosis H37Rv. Protein Expr Purif 2002;26:59-64.
-
Magalhães MLB, Pereira CP, Basso LA, Santos DS, Cloning and expression of functional shikimate dehydrogenase (EC 1.1.1.25) from Mycobacterium tuberculosis H37Rv. Protein Expr Purif 2002;26:59-64.
-
-
-
-
19
-
-
33645450273
-
Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: Purification and characterization
-
Fonseca IO, Magalhães ML, Oliveira JS, Silva RG, Mendes MA, Palma MS, Santos DS, Basso LA. Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: purification and characterization. Protein Expr Purif 2006;46:429-437.
-
(2006)
Protein Expr Purif
, vol.46
, pp. 429-437
-
-
Fonseca, I.O.1
Magalhães, M.L.2
Oliveira, J.S.3
Silva, R.G.4
Mendes, M.A.5
Palma, M.S.6
Santos, D.S.7
Basso, L.A.8
-
20
-
-
33845989426
-
Kinetic and chemical mechanisms of shikimate dehydrogenase from Mycobacterium tuberculosis
-
Fonseca IO, Silva RG, Fernandes CL, Souza ON, Basso LA, Santos DS. Kinetic and chemical mechanisms of shikimate dehydrogenase from Mycobacterium tuberculosis. Arch Biochem Biophys 2007;457:123-133.
-
(2007)
Arch Biochem Biophys
, vol.457
, pp. 123-133
-
-
Fonseca, I.O.1
Silva, R.G.2
Fernandes, C.L.3
Souza, O.N.4
Basso, L.A.5
Santos, D.S.6
-
21
-
-
0028871804
-
How to measure and predict the molar absorption coefficient of a protein
-
Pace CN, Vajdos F, Fee L, Grimsley G, Gray T. How to measure and predict the molar absorption coefficient of a protein. Protein Sci 1995;4:2411-2423.
-
(1995)
Protein Sci
, vol.4
, pp. 2411-2423
-
-
Pace, C.N.1
Vajdos, F.2
Fee, L.3
Grimsley, G.4
Gray, T.5
-
22
-
-
0026530383
-
Quantitative analysis of protein far UV circular dichroism spectra by neural networks
-
Böhm G, Muhr R, Jaenicke R. Quantitative analysis of protein far UV circular dichroism spectra by neural networks. Protein Eng 1992;5:191-195.
-
(1992)
Protein Eng
, vol.5
, pp. 191-195
-
-
Böhm, G.1
Muhr, R.2
Jaenicke, R.3
-
23
-
-
33747076386
-
Phosphate induces conformational changes in 5-enol-pyruvylshikimate-3-phosphate synthase from Mycobacterium tuberculosis
-
Borges JC, Pereira JH, Oliveira JS, Santos GC, Olivieri JR, Ramos CHI, Palma MS, Basso LA, Santos DS, de Azevedo WF, Jr. Phosphate induces conformational changes in 5-enol-pyruvylshikimate-3-phosphate synthase from Mycobacterium tuberculosis. Arch Biochem Biophys 2006;452:156-164.
-
(2006)
Arch Biochem Biophys
, vol.452
, pp. 156-164
-
-
Borges, J.C.1
Pereira, J.H.2
Oliveira, J.S.3
Santos, G.C.4
Olivieri, J.R.5
Ramos, C.H.I.6
Palma, M.S.7
Basso, L.A.8
Santos, D.S.9
de Azevedo Jr., W.F.10
-
24
-
-
0035878724
-
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements
-
Schaffer AA, Aravind L, Madden TL, Shavirin S, Spouge JL, Wolf YI, Koonin EV, Altschul SF. Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements. Nucleic Acids Res 2001;29:2994-3005.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 2994-3005
-
-
Schaffer, A.A.1
Aravind, L.2
Madden, T.L.3
Shavirin, S.4
Spouge, J.L.5
Wolf, Y.I.6
Koonin, E.V.7
Altschul, S.F.8
-
25
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 1997;25:3389-3402.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
26
-
-
0033954256
-
The protein data bank
-
Berman HM, Westbrook I, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE. The protein data bank. Nucleic Acids Res 2000;28:235-242.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, I.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
27
-
-
33847781998
-
Targets for development of drugs against orphan diseases
-
De Azevedo WF. Targets for development of drugs against orphan diseases. Curr Drug Targets 2007;8:387-387.
-
(2007)
Curr Drug Targets
, vol.8
, pp. 387-387
-
-
De Azevedo, W.F.1
-
28
-
-
33847705622
-
Mycobacterial shikimate pathway enzymes as targets for drug design
-
Ducati RG, Basso LA, Santos DS. Mycobacterial shikimate pathway enzymes as targets for drug design. Curr Drug Targets 2007;8:424-435.
-
(2007)
Curr Drug Targets
, vol.8
, pp. 424-435
-
-
Ducati, R.G.1
Basso, L.A.2
Santos, D.S.3
-
29
-
-
0027968068
-
CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position specific gap penalties and weight matrix choice
-
Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position specific gap penalties and weight matrix choice. Nucleic Acids Res 1994;22:4673-4680.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
31
-
-
0034663597
-
Application of multiple sequence alignment profiles to improve protein secondary structure prediction
-
Cuff JA, Barton GJ. Application of multiple sequence alignment profiles to improve protein secondary structure prediction. Proteins 2000;40:502-511.
-
(2000)
Proteins
, vol.40
, pp. 502-511
-
-
Cuff, J.A.1
Barton, G.J.2
-
32
-
-
0029768873
-
Predition of the three-dimensional structure of human interleukin-7 by homology modeling
-
Kroemer RT, Doughty SW, Robinson AJ, Richards WG. Predition of the three-dimensional structure of human interleukin-7 by homology modeling. Protein Eng 1996;9:493-498.
-
(1996)
Protein Eng
, vol.9
, pp. 493-498
-
-
Kroemer, R.T.1
Doughty, S.W.2
Robinson, A.J.3
Richards, W.G.4
-
33
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
Sali A, Blundell TL. Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 1993;234:779-815.
-
(1993)
J Mol Biol
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
34
-
-
0028051828
-
Derivation of rules for comparative protein modeling from a database of protein structure alignments
-
Sali A, Overington JP. Derivation of rules for comparative protein modeling from a database of protein structure alignments. Protein Sci 1994;3:1582-1596.
-
(1994)
Protein Sci
, vol.3
, pp. 1582-1596
-
-
Sali, A.1
Overington, J.P.2
-
35
-
-
0028871814
-
Evaluation of comparative protein modeling by MODELLER
-
Sali A, Potterton L, Yuan F, van Vlijmen H, Karplus M. Evaluation of comparative protein modeling by MODELLER. Proteins 1995;23:318-326.
-
(1995)
Proteins
, vol.23
, pp. 318-326
-
-
Sali, A.1
Potterton, L.2
Yuan, F.3
van Vlijmen, H.4
Karplus, M.5
-
36
-
-
0028991962
-
Modeling mutations and homologous proteins
-
Sali A. Modeling mutations and homologous proteins. Curr Opin Biotechnol 1995;6:437-451.
-
(1995)
Curr Opin Biotechnol
, vol.6
, pp. 437-451
-
-
Sali, A.1
-
37
-
-
84986512474
-
-
Brooks BR, Bruccoleri RE, Olafson BD, States DJ, Swaminathan S, Karplus M. CHARMM: a program for macromolecular energy minimization and dynamics calculations. J Comput Chem 1993;4:187-217.
-
Brooks BR, Bruccoleri RE, Olafson BD, States DJ, Swaminathan S, Karplus M. CHARMM: a program for macromolecular energy minimization and dynamics calculations. J Comput Chem 1993;4:187-217.
-
-
-
-
38
-
-
26844527626
-
High order analytic translation matrix elements for real space six-dimensional polar fourier correlations
-
Ritchie DW. High order analytic translation matrix elements for real space six-dimensional polar fourier correlations. J Appl Crystallogr 2005;38:808-818.
-
(2005)
J Appl Crystallogr
, vol.38
, pp. 808-818
-
-
Ritchie, D.W.1
-
39
-
-
0022336792
-
Calculation of protein conformations by proton-proton distance constraints. A new efficient algorithm
-
Braun W, Go N. Calculation of protein conformations by proton-proton distance constraints. A new efficient algorithm. J Mol Biol 1986;186:611-626.
-
(1986)
J Mol Biol
, vol.186
, pp. 611-626
-
-
Braun, W.1
Go, N.2
-
40
-
-
8844259837
-
-
Uchôa HB, Jorge GE, da Silveira NJ, Câmera JC, Canduri F, De Azevedo WF. Parmodel: a web server for automated comparative modeling of proteins. Biochem Biophys Res Commun 2004;325:1481-1486.
-
Uchôa HB, Jorge GE, da Silveira NJ, Câmera JC, Canduri F, De Azevedo WF. Parmodel: a web server for automated comparative modeling of proteins. Biochem Biophys Res Commun 2004;325:1481-1486.
-
-
-
-
41
-
-
46449124842
-
-
Laskowski RA, MacArthur MW, Smith DK, Jones DT, Hutchinson EG, Morris AL, Naylor D, Moss DS, Thornton JM. PROCHECK v. 3.0 - program to check the stereochemistry quality of protein structures - operating instructions. 1994.
-
Laskowski RA, MacArthur MW, Smith DK, Jones DT, Hutchinson EG, Morris AL, Naylor D, Moss DS, Thornton JM. PROCHECK v. 3.0 - program to check the stereochemistry quality of protein structures - operating instructions. 1994.
-
-
-
-
42
-
-
46449084415
-
-
Brünger AT. X-PLOR Version 3.1: a system for crystallography and NMR. New Haven, CT: Yale University Press; 1992
-
Brünger AT. X-PLOR Version 3.1: a system for crystallography and NMR. New Haven, CT: Yale University Press; 1992.
-
-
-
-
43
-
-
0028103275
-
4. The CCP4 suite: Programs for proteins crystallography
-
Collaborative Computational Project No
-
Collaborative Computational Project No. 4. The CCP4 suite: programs for proteins crystallography. Acta Crystallogr D Biol Crystallogr 1994;50:760-763.
-
(1994)
Acta Crystallogr D Biol Crystallogr
, vol.50
, pp. 760-763
-
-
-
45
-
-
0025830469
-
A method to identify protein sequences that fold into a known three-dimensional structure
-
Bowie JU, Luthy R, Eisenberg D. A method to identify protein sequences that fold into a known three-dimensional structure. Science 1991;253:164-170.
-
(1991)
Science
, vol.253
, pp. 164-170
-
-
Bowie, J.U.1
Luthy, R.2
Eisenberg, D.3
-
46
-
-
0026610767
-
Assessment of protein models with three-dimensional profiles
-
Luthy R, Bowie J, Eisenberg D, Assessment of protein models with three-dimensional profiles. Nature 1992;356:83-85.
-
(1992)
Nature
, vol.356
, pp. 83-85
-
-
Luthy, R.1
Bowie, J.2
Eisenberg, D.3
-
47
-
-
0020997912
-
Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
-
Kabsch W, Sander C. Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. Biopolymers 1983;22:2577-2637.
-
(1983)
Biopolymers
, vol.22
, pp. 2577-2637
-
-
Kabsch, W.1
Sander, C.2
-
48
-
-
0001229341
-
Calculation of hydrodynamic properties of globular proteins from their atomic-level structure
-
García de la Torre J, Huertas ML, Carrasco B. Calculation of hydrodynamic properties of globular proteins from their atomic-level structure. Biophys J 2000;78:719-730.
-
(2000)
Biophys J
, vol.78
, pp. 719-730
-
-
García de la Torre, J.1
Huertas, M.L.2
Carrasco, B.3
-
49
-
-
32644444805
-
Expression, purification and properties of shikimate dehydrogenase from Mycobacterium tuberculosis
-
Zhang X, Zhang S, Hao F, Lai X, Yu H, Huang Y, Wang H. Expression, purification and properties of shikimate dehydrogenase from Mycobacterium tuberculosis. J Biochem Mol Biol 2005;38:624-631.
-
(2005)
J Biochem Mol Biol
, vol.38
, pp. 624-631
-
-
Zhang, X.1
Zhang, S.2
Hao, F.3
Lai, X.4
Yu, H.5
Huang, Y.6
Wang, H.7
-
50
-
-
0042131870
-
Shikimate dehydrogenase structure reveals novel fold
-
Vogan E. Shikimate dehydrogenase structure reveals novel fold. Structure 2003;11:902-903.
-
(2003)
Structure
, vol.11
, pp. 902-903
-
-
Vogan, E.1
-
51
-
-
0030028728
-
Principles of protein-protein interactions derived from structural studies
-
Jones S, Thornton JM. Principles of protein-protein interactions derived from structural studies. Proc Natl Acad Sci USA 1996;93:13-20.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13-20
-
-
Jones, S.1
Thornton, J.M.2
|