Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori

FEBS Journal

Volumn 273, Issue 20, 2006, Pages 4682-4692

  Han, Cong ^a   Wang, Lirui ^a   Yu, Kunqian ^a   Chen, Lili ^a   Hu, Lihong ^a   Chen, Kaixian ^a   Jiang, Hualiang ^a,b   Shen, Xu ^a,b  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Antibacterial agent; Drug target; Enzyme inhibition; Helicobacter pylori; Shikimate dehydrogenase

Indexed keywords

2 [[2 [[2[(2 (2,3 DIMETHYLANILINO) 2 OXOETHYL]SULFANYL] 1,3 BENZOTHIAZOL 6 YL]AMINO] 2 OXOETHYL]SULFANYL] N (2 NAPHTHYL)ACETAMIDE; 3 (2 NAPHTHYLOXY) 4 OXO 2 (TRIFLUOROMETHYL) 4H CHROMEN 7 YL 3 CHLOROBENZOATE; BACTERIAL ENZYME; BUTYL 2 [[3 (2 NAPHTHYLOXY) 4 OXO 2 (TRIFLUOROMETHYL) 4H CHROMEN 7 YL]OXY]PROPANOATE; CURCUMIN; ENZYME INHIBITOR; MAESAQUINONE DIACETATE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RECOMBINANT ENZYME; SHIKIMATE DEHYDROGENASE; SHIKIMATE DEHYDROGENASE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE IDENTIFICATION; GROWTH INHIBITION; HELICOBACTER PYLORI; HIGH THROUGHPUT SCREENING; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CIRCULAR DICHROISM; CLONING, MOLECULAR; ENZYME INHIBITORS; GENE EXPRESSION; HELICOBACTER PYLORI; MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT;

ESCHERICHIA COLI; HELICOBACTER PYLORI;

EID: 33749396618     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05469.x     Document Type: Article

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